Featured Research

from universities, journals, and other organizations

Building better brain implants: The challenge of longevity

Date:
August 20, 2013
Source:
Journal of Visualized Experiments (JOVE)
Summary:
A new technique accommodates two challenges inherent in brain-implantation technology: gauging the property changes that occur during implantation and measuring them on a micro-scale.

In this experiment, we describe a method for environmentally-controlled microtensile testing of mechanically-adaptive polymer nanocomposites for ex-vivo characterization.
Credit: The Journal of Visualized Experiments

On August 20, JoVE, the Journal of Visualized Experiments will publish a technique from the Capadona Lab at Case Western Reserve University to accommodate two challenges inherent in brain-implantation technology, gauging the property changes that occur during implantation and measuring on a micro-scale. These new techniques open the doors for solving a great challenge for bioengineers -- crafting a device that can withstand the physiological conditions in the brain for the long-term.

"We created an instrument to measure the mechanical properties of micro-scale biomedical implants, after being explanted from living animals," explained the lab's principal investigator, Dr. Jeffrey R. Capadona. By preserving the changing properties that occurred during implantation even after removal, the technique offers potential to create and test new materials for brain implant devices. It could result in producing longer lasting and better suited devices for the highly-tailored functions.

For implanted devices, withstanding the high-temperatures, moisture, and other in-vivo properties poses a challenge to longevity. Resulting changes in stiffness, etc, of an implanted material can trigger a greater inflammatory response. "Often, the body's reaction to those implants causes the device to prematurely fail," says Dr. Capadona, "In some cases, the patient requires regular brain surgery to replace or revise the implants."

New implantation materials may help find solutions to restore motor function in individuals who have suffered from spinal cord injuries, stroke or multiple sclerosis. "Microelectrodes embedded chronically in the brain could hold promise for using neural activity to restore motor function in individuals who have, suffered from spinal cord injuries," said Dr. Capadona.

Furthermore, Capadona and his colleagues' method allows for measurement of mechanical properties using microsize scales. Previous methods typically require large or nano-sized samples of material, and data has to be scaled, which doesn't always work.

When asked why Dr. Capadona and his colleagues published their methods with JoVE, he responded "We choose JoVE because of the novel format to show readers visually what we are doing. If a picture is worth [a] thousand words, a video is worth a million."


Story Source:

The above story is based on materials provided by Journal of Visualized Experiments (JOVE). Note: Materials may be edited for content and length.


Journal Reference:

  1. Allison E. Hess, Kelsey A. Potter, Dustin J. Tyler, Christian A. Zorman, Jeffrey R. Capadona. Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization. Journal of Visualized Experiments, 2013; (78) DOI: 10.3791/50078

Cite This Page:

Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. ScienceDaily, 20 August 2013. <www.sciencedaily.com/releases/2013/08/130820094418.htm>.
Journal of Visualized Experiments (JOVE). (2013, August 20). Building better brain implants: The challenge of longevity. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2013/08/130820094418.htm
Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. www.sciencedaily.com/releases/2013/08/130820094418.htm (accessed August 30, 2014).

Share This




More Matter & Energy News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Australian Airlines Relax Phone Ban Too

Australian Airlines Relax Phone Ban Too

Reuters - Business Video Online (Aug. 26, 2014) Qantas and Virgin say passengers can use their smartphones and tablets throughout flights after a regulator relaxed a ban on electronic devices during take-off and landing. As Hayley Platt reports the move comes as the two domestic rivals are expected to post annual net losses later this week. Video provided by Reuters
Powered by NewsLook.com
Hurricane Marie Brings Big Waves to California Coast

Hurricane Marie Brings Big Waves to California Coast

Reuters - US Online Video (Aug. 26, 2014) Huge waves generated by Hurricane Marie hit the Southern California coast. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Chinese Researchers Might Be Creating Supersonic Submarine

Chinese Researchers Might Be Creating Supersonic Submarine

Newsy (Aug. 26, 2014) Chinese researchers have expanded on Cold War-era tech and are closer to building a submarine that could reach the speed of sound. Video provided by Newsy
Powered by NewsLook.com
Breakingviews: India Coal Strained by Supreme Court Ruling

Breakingviews: India Coal Strained by Supreme Court Ruling

Reuters - Business Video Online (Aug. 26, 2014) An acute coal shortage is likely to be aggravated as India's supreme court declared government coal allocations illegal, says Breakingviews' Peter Thal Larsen. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins