Featured Research

from universities, journals, and other organizations

Building better brain implants: The challenge of longevity

Date:
August 20, 2013
Source:
Journal of Visualized Experiments (JOVE)
Summary:
A new technique accommodates two challenges inherent in brain-implantation technology: gauging the property changes that occur during implantation and measuring them on a micro-scale.

In this experiment, we describe a method for environmentally-controlled microtensile testing of mechanically-adaptive polymer nanocomposites for ex-vivo characterization.
Credit: The Journal of Visualized Experiments

On August 20, JoVE, the Journal of Visualized Experiments will publish a technique from the Capadona Lab at Case Western Reserve University to accommodate two challenges inherent in brain-implantation technology, gauging the property changes that occur during implantation and measuring on a micro-scale. These new techniques open the doors for solving a great challenge for bioengineers -- crafting a device that can withstand the physiological conditions in the brain for the long-term.

Related Articles


"We created an instrument to measure the mechanical properties of micro-scale biomedical implants, after being explanted from living animals," explained the lab's principal investigator, Dr. Jeffrey R. Capadona. By preserving the changing properties that occurred during implantation even after removal, the technique offers potential to create and test new materials for brain implant devices. It could result in producing longer lasting and better suited devices for the highly-tailored functions.

For implanted devices, withstanding the high-temperatures, moisture, and other in-vivo properties poses a challenge to longevity. Resulting changes in stiffness, etc, of an implanted material can trigger a greater inflammatory response. "Often, the body's reaction to those implants causes the device to prematurely fail," says Dr. Capadona, "In some cases, the patient requires regular brain surgery to replace or revise the implants."

New implantation materials may help find solutions to restore motor function in individuals who have suffered from spinal cord injuries, stroke or multiple sclerosis. "Microelectrodes embedded chronically in the brain could hold promise for using neural activity to restore motor function in individuals who have, suffered from spinal cord injuries," said Dr. Capadona.

Furthermore, Capadona and his colleagues' method allows for measurement of mechanical properties using microsize scales. Previous methods typically require large or nano-sized samples of material, and data has to be scaled, which doesn't always work.

When asked why Dr. Capadona and his colleagues published their methods with JoVE, he responded "We choose JoVE because of the novel format to show readers visually what we are doing. If a picture is worth [a] thousand words, a video is worth a million."


Story Source:

The above story is based on materials provided by Journal of Visualized Experiments (JOVE). Note: Materials may be edited for content and length.


Journal Reference:

  1. Allison E. Hess, Kelsey A. Potter, Dustin J. Tyler, Christian A. Zorman, Jeffrey R. Capadona. Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization. Journal of Visualized Experiments, 2013; (78) DOI: 10.3791/50078

Cite This Page:

Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. ScienceDaily, 20 August 2013. <www.sciencedaily.com/releases/2013/08/130820094418.htm>.
Journal of Visualized Experiments (JOVE). (2013, August 20). Building better brain implants: The challenge of longevity. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2013/08/130820094418.htm
Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. www.sciencedaily.com/releases/2013/08/130820094418.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Matter & Energy News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Building Google Into Cars

Building Google Into Cars

Reuters - Business Video Online (Dec. 19, 2014) Google's next Android version could become the standard that'll power your vehicle's entertainment and navigation features, Reuters has learned. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
AP Review: Nikon D750 and GoPro Hero 4

AP Review: Nikon D750 and GoPro Hero 4

AP (Dec. 19, 2014) What to buy an experienced photographer or video shooter? There is some strong gear on the market from Nikon and GoPro. The AP's Ron Harris takes a closer look. (Dec. 19) Video provided by AP
Powered by NewsLook.com
Obama: Better Ways to Create Jobs Than Keystone Pipeline

Obama: Better Ways to Create Jobs Than Keystone Pipeline

AFP (Dec. 19, 2014) US President Barack Obama says that construction of the Keystone pipeline would have 'very little impact' on US gas prices and believes there are 'more direct ways' to create construction jobs. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins