Featured Research

from universities, journals, and other organizations

Building better brain implants: The challenge of longevity

Date:
August 20, 2013
Source:
Journal of Visualized Experiments (JOVE)
Summary:
A new technique accommodates two challenges inherent in brain-implantation technology: gauging the property changes that occur during implantation and measuring them on a micro-scale.

In this experiment, we describe a method for environmentally-controlled microtensile testing of mechanically-adaptive polymer nanocomposites for ex-vivo characterization.
Credit: The Journal of Visualized Experiments

On August 20, JoVE, the Journal of Visualized Experiments will publish a technique from the Capadona Lab at Case Western Reserve University to accommodate two challenges inherent in brain-implantation technology, gauging the property changes that occur during implantation and measuring on a micro-scale. These new techniques open the doors for solving a great challenge for bioengineers -- crafting a device that can withstand the physiological conditions in the brain for the long-term.

"We created an instrument to measure the mechanical properties of micro-scale biomedical implants, after being explanted from living animals," explained the lab's principal investigator, Dr. Jeffrey R. Capadona. By preserving the changing properties that occurred during implantation even after removal, the technique offers potential to create and test new materials for brain implant devices. It could result in producing longer lasting and better suited devices for the highly-tailored functions.

For implanted devices, withstanding the high-temperatures, moisture, and other in-vivo properties poses a challenge to longevity. Resulting changes in stiffness, etc, of an implanted material can trigger a greater inflammatory response. "Often, the body's reaction to those implants causes the device to prematurely fail," says Dr. Capadona, "In some cases, the patient requires regular brain surgery to replace or revise the implants."

New implantation materials may help find solutions to restore motor function in individuals who have suffered from spinal cord injuries, stroke or multiple sclerosis. "Microelectrodes embedded chronically in the brain could hold promise for using neural activity to restore motor function in individuals who have, suffered from spinal cord injuries," said Dr. Capadona.

Furthermore, Capadona and his colleagues' method allows for measurement of mechanical properties using microsize scales. Previous methods typically require large or nano-sized samples of material, and data has to be scaled, which doesn't always work.

When asked why Dr. Capadona and his colleagues published their methods with JoVE, he responded "We choose JoVE because of the novel format to show readers visually what we are doing. If a picture is worth [a] thousand words, a video is worth a million."


Story Source:

The above story is based on materials provided by Journal of Visualized Experiments (JOVE). Note: Materials may be edited for content and length.


Journal Reference:

  1. Allison E. Hess, Kelsey A. Potter, Dustin J. Tyler, Christian A. Zorman, Jeffrey R. Capadona. Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization. Journal of Visualized Experiments, 2013; (78) DOI: 10.3791/50078

Cite This Page:

Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. ScienceDaily, 20 August 2013. <www.sciencedaily.com/releases/2013/08/130820094418.htm>.
Journal of Visualized Experiments (JOVE). (2013, August 20). Building better brain implants: The challenge of longevity. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2013/08/130820094418.htm
Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. www.sciencedaily.com/releases/2013/08/130820094418.htm (accessed July 24, 2014).

Share This




More Matter & Energy News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Creative Makeovers for Ugly Cellphone Towers

Creative Makeovers for Ugly Cellphone Towers

AP (July 24, 2014) Mobile phone companies and communities across the country are going to new lengths to disguise those unsightly cellphone towers. From a church bell tower to a flagpole, even a pencil, some towers are trying to make a point. (July 24) Video provided by AP
Powered by NewsLook.com
Algonquin Power Goes Activist on Its Target Gas Natural

Algonquin Power Goes Activist on Its Target Gas Natural

TheStreet (July 23, 2014) When The Deal's Amanda Levin exclusively reported that Gas Natural had been talking to potential suitors, the Ohio company responded with a flat denial, claiming its board had not talked to anyone about a possible sale. Lo and behold, Canadian utility Algonquin Power and Utilities not only had approached the company, but it did it three times. Its last offer was for $13 per share as Gas Natural's was trading at a 60-day moving average of about $12.50 per share. Now Algonquin, which has a 4.9% stake in Gas Natural, has taken its case to shareholders, calling on them to back its proposals or, possibly, a change in the target's board. Video provided by TheStreet
Powered by NewsLook.com
Robot Parking Valet Creates Stress-Free Travel

Robot Parking Valet Creates Stress-Free Travel

AP (July 23, 2014) 'Ray' the robotic parking valet at Dusseldorf Airport in Germany lets travelers to avoid the hassle of finding a parking spot before heading to the check-in desk. (July 23) Video provided by AP
Powered by NewsLook.com
Boeing Ups Outlook on 52% Profit Jump

Boeing Ups Outlook on 52% Profit Jump

Reuters - Business Video Online (July 23, 2014) Commercial aircraft deliveries rose seven percent at Boeing, prompting the aerospace company to boost full-year profit guidance- though quarterly revenues missed analyst estimates. Bobbi Rebell reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins