Featured Research

from universities, journals, and other organizations

Higher than normal levels of Vitamin B12 may indicate cancer risk

Date:
November 18, 2013
Source:
Journal of the National Cancer Institute
Summary:
Vitamin B12 (cobalamin [Cbl]) is essential for maintaining healthy bodily function, but higher than normal levels (reference range 200-600 pmol/L) may indicate that a patient is at risk of developing certain cancers, according to a study published. Previous studies had suggested an association between high Cbl levels and specific cancers.

Vitamin B12 (cobalamin [Cbl]) is essential for maintaining healthy bodily function but higher than normal levels (reference range 200-600 pmol/L) may indicate that a patient is at risk of developing certain cancers, according to a study published November 18 in the Journal of the National Cancer Institute. Previous studies had suggested an association between high Cbl levels and specific cancers.

Related Articles


To assess the association between high Cbl levels and risk of cancer of any type, Johan Arendt, BSc, of the Department of Clinical Epidemiology and the Department of Clinical Biochemistry of Aarhus University Hospital in Denmark, and colleagues used Danish Medical registries to review the records of 333,667 patients without cancer who had been referred for Cbl testing and to estimate the incidence of cancer in this population from 1998 to 2010.

The researchers excluded patients who had a cancer diagnosis before the date of plasma measurement and those who were receiving Cbl therapy. They found that the risk of cancer overall increased with higher Cbl levels, especially during the first year after measurement and for those with levels > 800pmol/L. They also found that after five years of follow-up, the risk for hematological and alcohol and smoking-related cancers remained high for those with levels > 800pmol/L.

The authors conclude that "…high plasma Cbl levels increased the risk of subsequently diagnosed cancer, mostly within the first year of follow-up." However, Arendt et al. note that high plasma Cbl levels are probably not related to normal Vitamin B12 intake because consumption of Cbl containing foods or supplements do not increase plasma Cbl levels substantially. Rather, high Cbl levels may result from some unknown malignant process.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. F. B. Arendt, L. Pedersen, E. Nexo, H. T. Sorensen. Elevated Plasma Vitamin B12 Levels as a Marker for Cancer: A Population-Based Cohort Study. JNCI Journal of the National Cancer Institute, 2013; DOI: 10.1093/jnci/djt315

Cite This Page:

Journal of the National Cancer Institute. "Higher than normal levels of Vitamin B12 may indicate cancer risk." ScienceDaily. ScienceDaily, 18 November 2013. <www.sciencedaily.com/releases/2013/11/131118162805.htm>.
Journal of the National Cancer Institute. (2013, November 18). Higher than normal levels of Vitamin B12 may indicate cancer risk. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2013/11/131118162805.htm
Journal of the National Cancer Institute. "Higher than normal levels of Vitamin B12 may indicate cancer risk." ScienceDaily. www.sciencedaily.com/releases/2013/11/131118162805.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins