Featured Research

from universities, journals, and other organizations

Blood vessel tangles in brain best left alone, study suggests

Date:
November 20, 2013
Source:
University of Edinburgh
Summary:
Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.

Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.

Related Articles


An international patient trial suggests that the safest way of managing arteriovenous malformations (AVM) of the brain is to treat the patient's symptoms only, and not the AVM.

People with an AVM -- causing disrupted blood flow in the brain -- are three times more likely to suffer stroke from the AVM bursting or die within three years if the tangled vessels are treated, researchers found.

An AVM occurs when blood passes directly from arteries to veins -- normally arteries carry blood from the heart to the brain, while veins take blood back in the opposite direction.

More than 200 patients with a brain AVM were followed for 33 months in a trial, which was led in the UK by the University of Edinburgh.

The risks linked to treatment of AVMs were much higher than those associated with leaving them alone, the trial found.

The findings build on previous research showing that annually, only one in every hundred patients with a brain AVM suffer a stroke, and the other 99 per cent do not.

Doctors say that if a brain AVM ruptures, the initial effects are often mild.

Common symptoms of the condition include headaches and epilepsy.

Professor Rustam Al-Shahi Salman, of the University of Edinburgh's Division of Clinical Neurosciences, said: "We have found clear evidence of harm to patients in the short term from treatments to obliterate AVMs that have never bled in the past. Observation of trial participants must continue for at least another five years to find out if this difference persists."


Story Source:

The above story is based on materials provided by University of Edinburgh. Note: Materials may be edited for content and length.


Journal Reference:

  1. J P Mohr, Michael K Parides, Christian Stapf, Ellen Moquete, Claudia S Moy, Jessica R Overbey, Rustam Al-Shahi Salman, Eric Vicaut, William L Young, Emmanuel Houdart, Charlotte Cordonnier, Marco A Stefani, Andreas Hartmann, Rόdiger von Kummer, Alessandra Biondi, Joachim Berkefeld, Catharina J M Klijn, Kirsty Harkness, Richard Libman, Xavier Barreau, Alan J Moskowitz. Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial. The Lancet, 2013; DOI: 10.1016/S0140-6736(13)62302-8

Cite This Page:

University of Edinburgh. "Blood vessel tangles in brain best left alone, study suggests." ScienceDaily. ScienceDaily, 20 November 2013. <www.sciencedaily.com/releases/2013/11/131120103615.htm>.
University of Edinburgh. (2013, November 20). Blood vessel tangles in brain best left alone, study suggests. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2013/11/131120103615.htm
University of Edinburgh. "Blood vessel tangles in brain best left alone, study suggests." ScienceDaily. www.sciencedaily.com/releases/2013/11/131120103615.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) — Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) — Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) — According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) — A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins