Featured Research

from universities, journals, and other organizations

Concussion history associated with risk of Alzheimer's disease

Date:
December 26, 2013
Source:
Mayo Clinic
Summary:
A new study suggests that a history of concussion involving at least a momentary loss of consciousness may be related to the buildup of Alzheimer’s-associated plaques in the brain.

A new study suggests that a history of concussion involving at least a momentary loss of consciousness may be related to the buildup of Alzheimer's-associated plaques in the brain. The research is published in the Dec. 26, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology. "Interestingly, in people with a history of concussion, a difference in the amount of brain plaques was found only in those with memory and thinking problems, not in those who were cognitively normal," says study author Michelle Mielke, Ph.D., a Mayo Clinic researcher.

For the study, people from Olmsted County in Minnesota were given brain scans; these included 448 people without any signs of memory problems and 141 people with memory and thinking problems called mild cognitive impairment. Participants, who were all age 70 or older, were also asked about whether they had ever experienced a brain injury that involved any loss of consciousness or memory.

Of the 448 people without any thinking or memory problems, 17 percent reported a brain injury and 18 percent of the 141 with memory and thinking difficulties reported a concussion or head trauma. The study found no difference in any brain scan measures among the people without memory and thinking impairments, whether or not they had head trauma. However, people with memory and thinking impairments and a history of head trauma had levels of amyloid plaques an average of 18 percent higher than those with no head trauma history.

"Our results add merit to the idea that concussion and Alzheimer's disease brain pathology may be related," Dr. Mielke says. "However, the fact that we did not find a relationship in those without memory and thinking problems suggests that any association between head trauma and amyloid is complex."


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Journal Reference:

  1. M. M. Mielke, R. Savica, H. J. Wiste, S. D. Weigand, P. Vemuri, D. S. Knopman, V. J. Lowe, R. O. Roberts, M. M. Machulda, Y. E. Geda, R. C. Petersen, C. R. Jack. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study. Neurology, 2013; 82 (1): 70 DOI: 10.1212/01.wnl.0000438229.56094.54

Cite This Page:

Mayo Clinic. "Concussion history associated with risk of Alzheimer's disease." ScienceDaily. ScienceDaily, 26 December 2013. <www.sciencedaily.com/releases/2013/12/131226181605.htm>.
Mayo Clinic. (2013, December 26). Concussion history associated with risk of Alzheimer's disease. ScienceDaily. Retrieved August 27, 2014 from www.sciencedaily.com/releases/2013/12/131226181605.htm
Mayo Clinic. "Concussion history associated with risk of Alzheimer's disease." ScienceDaily. www.sciencedaily.com/releases/2013/12/131226181605.htm (accessed August 27, 2014).

Share This




More Mind & Brain News

Wednesday, August 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Stroke in Young Adults

Stroke in Young Adults

Ivanhoe (Aug. 27, 2014) A stroke can happen at any time and affect anyone regardless of age. This mother chose to give her son independence and continue to live a normal life after he had a stroke at 18 years old. Video provided by Ivanhoe
Powered by NewsLook.com
Distracted Adults: ADHD?

Distracted Adults: ADHD?

Ivanhoe (Aug. 27, 2014) Most people don’t realize that ADHD isn’t just for kids. It can affect the work as well as personal lives of many adults, and often times they don’t even know they have it. Video provided by Ivanhoe
Powered by NewsLook.com
The Sight and Sounds of Autism

The Sight and Sounds of Autism

Ivanhoe (Aug. 27, 2014) A new study is explaining why for some people with autism what they see and what they hear is out of sync. Video provided by Ivanhoe
Powered by NewsLook.com
Experiences Make Us Happy, Even Just Waiting For Them

Experiences Make Us Happy, Even Just Waiting For Them

Newsy (Aug. 27, 2014) New research finds we get more excited to buy experiences than we do to buy material things. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins