Featured Research

from universities, journals, and other organizations

Vascular disease that affects mostly women is 'poorly understood' by many health care providers

Date:
February 25, 2014
Source:
Loyola University Health System
Summary:
A vascular disease called fibromuscular dysplasia (FMD), which can cause high blood pressure, kidney failure, stroke and other symptoms -- mostly in women -- is “poorly understood by many healthcare providers,” according to a Scientific Statement from the American Heart Association. FMD can cause narrowing, enlargement, bulging or tears in medium-size arteries, and occurs most commonly in arteries leading to the kidneys, and in carotid arteries in the neck that carry blood to the brain and eyes. It also can affect arteries supplying blood to the abdominal organs, legs or arms. Neurological complications include headaches, neck pain, tinnitus, strokes and mini strokes. A delay in diagnosis 'can lead to impaired quality of life and poor outcomes.'

A vascular disease called fibromuscular dysplasia, which can cause high blood pressure, kidney failure, stroke and other symptoms -- mostly in women -- is "poorly understood by many healthcare providers," according to a Scientific Statement from the American Heart Association.

Neurologist Jose Biller, MD, of Loyola University Medical Center, is a co-author of the statement, published online ahead of print in the American Heart Association journal Circulation. First author is Jeffrey W. Olin, DO of Mount Sinai School of Medicine.

Biller said FMD "is a relatively uncommon and often undiagnosed arterial condition of unknown cause."

Biller is an internationally known stroke specialist and chair of the Department of Neurology of Loyola University Chicago Stritch School of Medicine. He is a member of the multidisciplinary group of vascular experts who wrote the American Heart Association's Scientific Statement on fibromuscular dysplasia (FMD).

FMD can cause narrowing, enlargement, bulging or tears in medium-size arteries. FMD occurs most commonly in arteries leading to the kidneys, and in carotid arteries in the neck that carry blood to the brain and eyes. It also can affect arteries supplying blood to the abdominal organs, legs or arms. Neurological complications include headaches, neck pain, tinnitus (swishing sounds in the ears), strokes and transient ischemic attacks (mini strokes). FMD may be a predisposing condition for cervical arterial dissections (tears in neck arteries). It also can cause brain aneurysms or bleeding on the surface of the brain.

FMD "is poorly understood by many healthcare providers," the Scientific Statement said. A delay in diagnosis "can lead to impaired quality of life and poor outcomes."

The condition was first described in a medical journal in 1938, and given the name fibromuscular dysplasia in 1958.

Although the prevalence in the general population is unknown, 91 percent of patients with FMD are female, the Scientific Statement said. Although the cause is unknown, there appears to be a genetic basis for susceptibility to FMD.

The Scientific Statement lists several common misconceptions regarding FMD. One misconception is that the most common presentation for FMD in the carotid artery is a stroke or mini stroke. In fact, while strokes and mini strokes can occur with carotid FMD, the most common presentations are nonspecific symptoms such as headaches, dizziness, light-headedness and tinnitus.

FMD often is misdiagnosed as other conditions, such as atherosclerosis and vasculitis. The gold standard for correctly diagnosing FMD is a catheter-based angiogram.

Advances in imaging and therapies "have made the treatment for patients with FMD less invasive, safer and more effective," the Scientific Statement said.

But there is a great need for more research, the statement said. "Significant advances in our understanding of FMD will undoubtedly require collaboration across a large network of research and clinical centers in the United States and abroad," the statement said.

The Fibromuscular Dysplasia Society of America praised the Scientific Statement. "The authors did a great job and covered all areas of FMD, including history of the disease, diagnosis, imaging, treatment and research," the society said on its website.


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. W. Olin, H. L. Gornik, J. M. Bacharach, J. Biller, L. J. Fine, B. H. Gray, W. A. Gray, R. Gupta, N. M. Hamburg, B. T. Katzen, R. A. Lookstein, A. B. Lumsden, J. W. Newburger, T. Rundek, C. J. Sperati, J. C. Stanley. Fibromuscular Dysplasia: State of the Science and Critical Unanswered Questions: A Scientific Statement From the American Heart Association. Circulation, 2014; DOI: 10.1161/01.cir.0000442577.96802.8c

Cite This Page:

Loyola University Health System. "Vascular disease that affects mostly women is 'poorly understood' by many health care providers." ScienceDaily. ScienceDaily, 25 February 2014. <www.sciencedaily.com/releases/2014/02/140225100947.htm>.
Loyola University Health System. (2014, February 25). Vascular disease that affects mostly women is 'poorly understood' by many health care providers. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2014/02/140225100947.htm
Loyola University Health System. "Vascular disease that affects mostly women is 'poorly understood' by many health care providers." ScienceDaily. www.sciencedaily.com/releases/2014/02/140225100947.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com
House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Uganda on Alert for Ebola but No Confirmed Cases

Uganda on Alert for Ebola but No Confirmed Cases

AFP (July 31, 2014) Uganda's health minister said on Thursday that there are no confirmed cases of Ebola in the country, but that it remained on alert for cases of the deadly virus. Uganda has suffered Ebola outbreaks in the past, most recently in 2012. Duration: 00:59 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins