Featured Research

from universities, journals, and other organizations

Does germ plasm accelerate evolution?

Date:
April 14, 2014
Source:
University of Nottingham
Summary:
Scientists have challenged a long held belief about the way certain species of vertebrates evolved. They found that genes evolve more rapidly in species containing germ plasm. The results came about as they put to the test a novel theory that early developmental events dramatically alter the vertebrate body plan and the way evolution proceeds.

Tadpoles. According to Dr Johnson's theory, vertebrates such as frogs, fruit flies and birds, which look unlike their ancestors, came about, and remarkably evolved much faster than their ancestors did.
Credit: dabjola / Fotolia

Scientists at The University of Nottingham have published research in the journal Science that challenges a long held belief about the way certain species of vertebrates evolved.

Related Articles


Dr Matt Loose and Dr Andrew Johnson who are experts in genetics and cell development in the School of Life Sciences carried out the research, funded by the Medical Research Council (MRC). It suggests that genes evolve more rapidly in species containing germ plasm. The results came about as they put to the test a novel theory that early developmental events dramatically alter the vertebrate body plan and the way evolution proceeds.

The original theory was proposed by Dr Johnson over 10 years ago. His view is that the relationship between the germ line (hereditary germ cells that create sperm and eggs) and the soma (cells which form the body of an organism) also impacts on species diversity. He argues that once a species evolves a substance called germ plasm, germ cells are independent of other cells, so constraints on somatic development are liberated and this enhances a species' ability to evolve. As a result, he says, vertebrates such as frogs, fruit flies and birds, which look unlike their ancestors, came about, and remarkably they evolved much faster than their ancestors did.

Taking a new look at embryology

Early in animal development a subset of cells in an embryo becomes committed to produce Primordial Germ Cells (PGCs). PGCs develop into sperm or eggs. The remaining cells develop as the soma, a term that describes all of the tissues that make up an individual's body. The germ line is an immortal cell lineage, passed on from generation to generation, and charged solely with producing a new embryo at fertilisation. The soma, on the other hand, dies off in every generation. In the most classic biological sense its job is to interpret the effects of natural selection in order to determine genetic fitness, leading to so called 'survival of the fittest'.

There are two known ways to make a PGC. There is preformation -- material in the egg called germ plasm is inherited directly by a few cells in the embryo, and germ plasm instructs these cells to become PGCs. Alternatively, PGCs can develop without germ plasm. In this case PGCs can be induced to form by signals secreted from other cells, which are part of the soma. This is called epigenesis.

Dr Johnson said: "Biologists are accustomed to thinking about how adult somatic traits impact natural selection and the evolution of new species. What is much less clear is the role of embryological mechanisms in evolution, and how they might contribute to species diversity."

A new computer programme tested their hypothesis In this latest publication Dr Loose put this theory to the test. He said: "To investigate the effect germ plasm has on sequence changes we had to look at as many sequences as possible -- nearly 12 million sequences were analysed and processed from 165 different species including mammals, reptiles, amphibians and fish."

With graduate student Teri Evans, Dr Loose wrote computer programmes to process these sequences and test the hypothesis. They compared DNA sequences from species that contain germ plasm with related species that use epigenesis instead. So, for example, they compared DNA from salamanders (epigenesis) with frogs (germ plasm), both of which are amphibians. Unexpectedly, they found that species with germ plasm have a faster rate of sequence change than those without. Thus, frogs evolve faster than salamanders. Similar comparisons with fish and reptile species identify the same pattern, suggesting it is a generalised feature of animal evolution. These results support the theory that germ plasm provides a selective advantage because it enables more rapid evolution. In addition, they support the view that the relationship between development of the germ line and soma shapes species diversity in the animal kingdom.

Dr Johnson said: "What Matt and I have been working on would not normally have been predicted. This paper shows that animals can evolve more rapidly with germ plasm. Typically evolution is thought to be a gradual process, but this work suggests that the evolution of germ plasm can lead to explosive radiations of species. Importantly, because of the accelerated rate of evolution, genetic similarities between species can differ from that expected from their phylogenetic relationships. This has broad implications across biological disciplines."

But the evolution of germ plasm comes at a price

One of the things that was initially intriguing was that early on we realized that embryos from animals with germ plasm were different than embryos that use epigenesis. In fact, the adult body forms of these animals were not like those of "typical vertebrates." This is why we developed the axolotl as an experimental model. Axolotls are "typical vertebrates," and they don't contain germ plasm. We found that the mechanisms that control axolotl development are conserved in mammalian embryos. However, they are not found in "conventional" models for vertebrate development, all of which have germ plasm. So when germ plasm evolves it leads to evolutionary dead ends. In other words, whereas salamander-like amphibians evolved into reptiles, then mammals, frogs could only evolve into other frogs. A lot of different frogs, but still just frogs. For this reason we think axolotl embryos have a very promising future as a model for human development.


Story Source:

The above story is based on materials provided by University of Nottingham. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. Evans, C. M. Wade, F. A. Chapman, A. D. Johnson, M. Loose. Acquisition of Germ Plasm Accelerates Vertebrate Evolution. Science, 2014; 344 (6180): 200 DOI: 10.1126/science.1249325

Cite This Page:

University of Nottingham. "Does germ plasm accelerate evolution?." ScienceDaily. ScienceDaily, 14 April 2014. <www.sciencedaily.com/releases/2014/04/140414091917.htm>.
University of Nottingham. (2014, April 14). Does germ plasm accelerate evolution?. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2014/04/140414091917.htm
University of Nottingham. "Does germ plasm accelerate evolution?." ScienceDaily. www.sciencedaily.com/releases/2014/04/140414091917.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
The Hottest Food Trends for 2015

The Hottest Food Trends for 2015

Buzz60 (Dec. 17, 2014) Urbanspoon predicts whicg food trends will dominate the culinary scene in 2015. Mara Montalbano (@maramontalbano) has the story. Video provided by Buzz60
Powered by NewsLook.com
Rover Finds More Clues About Possible Life On Mars

Rover Finds More Clues About Possible Life On Mars

Newsy (Dec. 17, 2014) NASA's Curiosity rover detected methane on Mars and organic compounds on the surface, but it doesn't quite prove there was life ... yet. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins