Featured Research

from universities, journals, and other organizations

Increased prevalence of celiac disease in children with irritable bowel syndrome

Date:
April 21, 2014
Source:
The JAMA Network Journals
Summary:
There appears to be an increased prevalence of celiac disease among children with irritable bowel syndrome. Recurrent abdominal pain affects 10 percent to 15 percent of school-aged children. The prevalence of celiac disease is as high as 1 percent in European countries and patients can present with a wide spectrum of symptoms, including abdominal pain, although the disease is often asymptomatic.

There appears to be an increased prevalence of celiac disease among children with irritable bowel syndrome (IBS).

Recurrent abdominal pain affects 10 percent to 15 percent of school-aged children. The prevalence of celiac disease is as high as 1 percent in European countries and patients can present with a wide spectrum of symptoms, including abdominal pain, although the disease is often asymptomatic.

The authors assessed the prevalence of celiac disease in 992 children with abdominal pain-related disorders: IBS, functional dyspepsia (indigestion) and functional abdominal pain. The final study group included 782 children: 270 with IBS, 201with functional dyspepsia and 311 with functional abdominal pain.

Blood tests were performed on all the children and 15 patients tested positive for celiac: 12 (4.4 percent) of the children with IBS, 2 (1 percent) of the children with functional dyspepsia and 1 (0.3 percent) of the children with functional abdominal pain. The prevalence of celiac among children with IBS was four times higher than the general pediatric population.

"The identification of IBS as a high-risk condition for celiac disease might be of help in pediatric primary care because it might have become routine to test for celiac disease indiscriminately in all children with recurrent abdominal pain, although our finding suggests that the screening should be extended only to those with IBS. This new approach might have important implications for the cost of care because it has been estimated that in children with FGIDs, screening tests are common, costs are substantial, and the yield is minimal."

Editorial: Role of Celiac Disease Screening for Children with Functional Gastrointestinal Disorders

In a related editorial, James E. Squires, M.D., and colleagues from Cincinnati Children's Hospital Medical Center, Ohio, write: "Based on the study by Cristofori et al, we suggest that selective screening for celiac disease is warranted for children with IBS but not for children with other FGIDS [functional gastrointestinal disorders]. However, the lines distinguishing IBS from alternative FGIDS are often blurred. It is within this reality that pediatric health care providers should examine the evidence, evaluate the patient and family, weigh the likelihood of a false positive test result, and make the decision that they believe will benefit the patient most."


Story Source:

The above story is based on materials provided by The JAMA Network Journals. Note: Materials may be edited for content and length.


Journal References:

  1. Fernanda Cristofori, Claudia Fontana, Annamaria Magistΰ, Teresa Capriati, Flavia Indrio, Stefania Castellaneta, Luciano Cavallo, Ruggiero Francavilla. Increased Prevalence of Celiac Disease Among Pediatric Patients With Irritable Bowel Syndrome. JAMA Pediatrics, 2014; DOI: 10.1001/jamapediatrics.2013.4984
  2. Dennis R. Durbin, Jessica Mirman, Allison Curry. Enhancing Our Understanding of Teen-Driver Crashes. JAMA Pediatrics, 2014; DOI: 10.1001/jamapediatrics.2013.5402

Cite This Page:

The JAMA Network Journals. "Increased prevalence of celiac disease in children with irritable bowel syndrome." ScienceDaily. ScienceDaily, 21 April 2014. <www.sciencedaily.com/releases/2014/04/140421164353.htm>.
The JAMA Network Journals. (2014, April 21). Increased prevalence of celiac disease in children with irritable bowel syndrome. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2014/04/140421164353.htm
The JAMA Network Journals. "Increased prevalence of celiac disease in children with irritable bowel syndrome." ScienceDaily. www.sciencedaily.com/releases/2014/04/140421164353.htm (accessed August 22, 2014).

Share This




More Health & Medicine News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) — An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) — Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) — Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) — It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins