Featured Research

from universities, journals, and other organizations

Anxious children have bigger 'fear centers' in the brain

Date:
June 16, 2014
Source:
Elsevier
Summary:
The amygdala is a key “fear center” in the brain. Alterations in the development of the amygdala during childhood may have an important influence on the development of anxiety problems, reports a new study. Researchers recruited 76 children, 7 to 9 years of age, a period when anxiety-related traits and symptoms can first be reliably identified. Using non-invasive magnetic resonance imaging (MRI) scans of brain structure and function, the researchers found that children with high levels of anxiety had enlarged amygdala volume.

The amygdala is a key "fear center" in the brain. Alterations in the development of the amygdala during childhood may have an important influence on the development of anxiety problems, reports a new study in the current issue of Biological Psychiatry.

Related Articles


Researchers at the Stanford University School of Medicine recruited 76 children, 7 to 9 years of age, a period when anxiety-related traits and symptoms can first be reliably identified. The children's parents completed assessments designed to measure the anxiety levels of the children, and the children then underwent non-invasive magnetic resonance imaging (MRI) scans of brain structure and function.

The researchers found that children with high levels of anxiety had enlarged amygdala volume and increased connectivity with other brain regions responsible for attention, emotion perception, and regulation, compared to children with low levels of anxiety. They also developed an equation that reliably predicted the children's anxiety level from the MRI measurements of amygdala volume and amygdala functional connectivity.

The most affected region was the basolateral portion of the amygdala, a subregion of the amygdala implicated in fear learning and the processing of emotion-related information.

"It is a bit surprising that alterations to the structure and connectivity of the amygdala were so significant in children with higher levels of anxiety, given both the young age of the children and the fact that their anxiety levels were too low to be observed clinically," commented Dr. Shaozheng Qin, first author on this study.

Dr. John Krystal, Editor of Biological Psychiatry, commented, "It is critical that we move from these interesting cross-sectional observations to longitudinal studies, so that we can separate the extent to which larger and better connected amygdalae are risk factors or consequences of increased childhood anxiety."

"However, our study represents an important step in characterizing altered brain systems and developing predictive biomarkers in the identification for young children at risk for anxiety disorders," Qin added. "Understanding the influence of childhood anxiety on specific amygdala circuits, as identified in our study, will provide important new insights into the neurodevelopmental origins of anxiety in humans."


Story Source:

The above story is based on materials provided by Elsevier. Note: Materials may be edited for content and length.


Journal Reference:

  1. Shaozheng Qin, Christina B. Young, Xujun Duan, Tianwen Chen, Kaustubh Supekar, Vinod Menon. Amygdala Subregional Structure and Intrinsic Functional Connectivity Predicts Individual Differences in Anxiety During Early Childhood. Biological Psychiatry, 2014; 75 (11): 892 DOI: 10.1016/j.biopsych.2013.10.006

Cite This Page:

Elsevier. "Anxious children have bigger 'fear centers' in the brain." ScienceDaily. ScienceDaily, 16 June 2014. <www.sciencedaily.com/releases/2014/06/140616093200.htm>.
Elsevier. (2014, June 16). Anxious children have bigger 'fear centers' in the brain. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2014/06/140616093200.htm
Elsevier. "Anxious children have bigger 'fear centers' in the brain." ScienceDaily. www.sciencedaily.com/releases/2014/06/140616093200.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com
Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Reuters - Innovations Video Online (Mar. 25, 2015) European researchers say our smartphone use offers scientists an ideal testing ground for human brain plasticity. Dr Ako Ghosh&apos;s team discovered that the brains and thumbs of smartphone users interact differently from those who use old-fashioned handsets. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Many Don't Know They Have Alzheimer's, But Their Doctors Do

Many Don't Know They Have Alzheimer's, But Their Doctors Do

Newsy (Mar. 24, 2015) According to a new study by the Alzheimer&apos;s Association, more than half of those who have the degenerative brain disease aren&apos;t told by their doctors. Video provided by Newsy
Powered by NewsLook.com
A Quick 45-Minute Nap Can Improve Your Memory

A Quick 45-Minute Nap Can Improve Your Memory

Newsy (Mar. 23, 2015) Researchers found those who napped for 45 minutes to an hour before being tested on information recalled it five times better than those who didn&apos;t. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins