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High levels of vitamin D is suspected of increasing mortality rates

Date:
March 10, 2015
Source:
University of Copenhagen - The Faculty of Health and Medical Sciences
Summary:
The level of vitamin D in our blood should neither be too high nor to low. Scientists have now shown that there is a connection between high levels of vitamin D and cardiovascular deaths.
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The level of vitamin D in our blood should neither be too high nor to low. Scientists from the University of Copenhagen are the first in the world to show that there is a connection between high levels of vitamin D and cardiovascular deaths.

In terms of public health, a lack of vitamin D has long been a focal point. Several studies have shown that too low levels can prove detrimental to our health. However, new research from the University of Copenhagen reveals, for the first time, that also too high levels of vitamin D in our blood is connected to an increased risk of dying from a stroke or a coronary.

The results have just been published in the Journal of Endocrinology and Metabolism.

"We have studied the level of vitamin D in 247,574 Danes, and so far, it constitutes the world's largest basis for this type of study. We have also analysed their mortality rate over a seven-year period after taking the initial blood sample, and in that time 16,645 patients had died. Furthermore, we have looked at the connection between their deaths and their levels of vitamin D," Professor at the Department of Clinical Medicine, Peter Schwarz explains.

The conclusion is clear: the study confirms that there is indeed a correlation between mortality rates and too low levels of vitamin D, but the new thing is that the level of vitamin D can also be too high.

"If your vitamin D level is below 50 or over 100 nanomol per litre, there is an greater connection to deaths. We have looked at what caused the death of patients, and when numbers are above 100, it appears that there is an increased risk of dying from a stroke or a coronary. In other words, levels of vitamin D should not be too low, but neither should they be too high. Levels should be somewhere in between 50 and 100 nanomol per litre, and our study indicates that 70 is the most preferable level," Peter Schwartz states.

That having too much vitamin D in our blood can be bad for our health has never been proven before, and it may have great influence on our future intake of nutritional supplements.

"These are very important results, because there is such great focus on eating vitamin D. We should use this information to ask ourselves whether or not we should continue to eat vitamins and nutritional supplements as if they were sweets. You shouldn't simply up the dose to feel better. We should only consume such vitamins in close coordination with our GP," Peter Schwartz concludes.


Story Source:

Materials provided by University of Copenhagen - The Faculty of Health and Medical Sciences. Note: Content may be edited for style and length.


Journal Reference:

  1. Darshana Durup, Henrik Løvendahl Jørgensen, Jane Christensen, Anne Tjønneland, Anja Olsen, Jytte Halkjær, Bent Lind, Anne-Marie Heegaard, Peter Schwarz. A reverse J-shaped association between serum 25-hydroxyvitamin D and cardiovascular disease mortality – the CopD-study. The Journal of Clinical Endocrinology & Metabolism, 2015; jc.2014-4551 DOI: 10.1210/jc.2014-4551

Cite This Page:

University of Copenhagen - The Faculty of Health and Medical Sciences. "High levels of vitamin D is suspected of increasing mortality rates." ScienceDaily. ScienceDaily, 10 March 2015. <www.sciencedaily.com/releases/2015/03/150310105222.htm>.
University of Copenhagen - The Faculty of Health and Medical Sciences. (2015, March 10). High levels of vitamin D is suspected of increasing mortality rates. ScienceDaily. Retrieved April 24, 2024 from www.sciencedaily.com/releases/2015/03/150310105222.htm
University of Copenhagen - The Faculty of Health and Medical Sciences. "High levels of vitamin D is suspected of increasing mortality rates." ScienceDaily. www.sciencedaily.com/releases/2015/03/150310105222.htm (accessed April 24, 2024).

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