Stronger muscles make for healthier bone development

A new study, published in the journal Bone, by researchers from the University's Medical Research Council Lifecourse Epidemiology Unit shows a link between the amount of lean muscle and healthy bone development, indicated by the size, shape and density of limb bones, in children at ages six and seven.

Detailed measurements of 200 children enrolled in the Southampton Women's Survey were taken soon after birth and then again at ages six to seven years old. State of the art scanning equipment was used to assess bone mineral density, shape and size of the tibia (the shin bone), and body composition.

"Bone strength and size is important because they are significant factors in long term osteoporosis and fracture risk," says Dr Rebecca Moon, lead investigator of the study.

"A ten per cent increase in peak bone mass will delay the onset of osteoporosis by 13 years. These findings point to the importance of early childhood physical activity to optimise muscle and bone growth."

The team also found that the relationship between changes in lean muscle and bone development was stronger in girls than in boys, despite the ages of the children ruling out the onset of puberty as a factor.

Professor Cyrus Cooper, Director of the MRC Lifecourse Epidemiology Unit, said: "This is a wonderful example of a biomedical discovery made by combining state of the art imaging methodologies with the world leading population science, for which Southampton has an established international reputation."