http://www.sciencedaily.com/news/health_medicine/lymphoma/ Learn about lymphoma. Read the latest research on lymphoma symptoms, diagnosis, current lymphoma treatments. Find information on different lymphoma types including non-Hodgkin's lymphoma. en-us Tue, 24 Nov 2009 17:05:01 EST Tue, 24 Nov 2009 17:05:01 EST 60 http://www.sciencedaily.com/images/logosmall.gif http://www.sciencedaily.com/news/health_medicine/lymphoma/ For more science articles, visit ScienceDaily. http://www.sciencedaily.com/releases/2009/11/091122161753.htm Physician-scientists have discovered a molecular mechanism that may prove to be a powerful target for the treatment of non-Hodgkin's lymphoma, a type of cancer that affects lymphocytes, or white blood cells. By exploiting this mechanism, researchers have been able to powerfully suppress tumor formation in lab testing and in animal models. Mon, 23 Nov 2009 08:00:00 EST http://www.sciencedaily.com/releases/2009/11/091122161753.htm http://www.sciencedaily.com/releases/2009/11/091116103441.htm Cancer researchers in Germany have gained new insights into how cells react to DNA damage. They have shown that the protein PARP-1, which detects DNA damage within seconds, activates the transcription factor NF-kappaB. NF-kappaB triggers a survival program, which blocks programmed cell death. The activation of NF-kappaB is thought to be one of the potential causes for tumor cell resistance to chemo and radiation therapy. Tue, 17 Nov 2009 02:00:00 EST http://www.sciencedaily.com/releases/2009/11/091116103441.htm http://www.sciencedaily.com/releases/2009/11/091102103336.htm High-risk melanoma patients who are treated with radiation after surgery have a significantly lower risk of their cancer returning to the lymph nodes (19 percent), compared to those patients who do not have radiation therapy (31 percent), according to the first randomized study of its kind. Tue, 10 Nov 2009 14:00:00 EST http://www.sciencedaily.com/releases/2009/11/091102103336.htm http://www.sciencedaily.com/releases/2009/11/091105102716.htm A drug already approved for the treatment of lymphoma may also slow the growth of the most deadly bone cancer in children and teens, according to an early-stage study. Mon, 09 Nov 2009 02:00:00 EST http://www.sciencedaily.com/releases/2009/11/091105102716.htm http://www.sciencedaily.com/releases/2009/11/091106145410.htm A small group of patients with severe Graves' eye disease experienced rapid improvement of their symptoms -- and improved vision -- following treatment with the drug rituximab. Inflammation around their eyes and damage to the optic nerve were significantly reduced. The same patients had not previously responded to steroids, a common treatment for Graves' eye disease. Sat, 07 Nov 2009 17:00:00 EST http://www.sciencedaily.com/releases/2009/11/091106145410.htm http://www.sciencedaily.com/releases/2009/10/091027162005.htm A healthy dose of exercise is good medicine, even for lymphoma patients receiving chemotherapy, University of Alberta researchers have found. Sat, 07 Nov 2009 05:00:00 EST http://www.sciencedaily.com/releases/2009/10/091027162005.htm http://www.sciencedaily.com/releases/2009/11/091105121048.htm For the first time, researchers have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options. Fri, 06 Nov 2009 17:00:00 EST http://www.sciencedaily.com/releases/2009/11/091105121048.htm http://www.sciencedaily.com/releases/2009/10/091031002506.htm Targeted immunotherapy has been an attractive new therapeutic area for a number of cancers because it has the potential to destroy tumor cells without damaging surrounding normal tissue. New study results demonstrate high success rates using specialized white blood cells to prevent or treat lymphoma associated with the Epstein-Barr virus (EBV-lymphoma) in patients who have received a hematopoietic stem cell transplant (HSCT). Mon, 02 Nov 2009 14:00:00 EST http://www.sciencedaily.com/releases/2009/10/091031002506.htm http://www.sciencedaily.com/releases/2009/11/091102103332.htm After mastectomy, breast cancer patients who receive radiation treatment to the lymph nodes located behind the breast bone do not live longer than those who do not receive radiation to this hard-to-treat area, according to a randomized 10-year study. Mon, 02 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091102103332.htm http://www.sciencedaily.com/releases/2009/10/091029125534.htm A specific type of T helper cell awakens the immune system to the stealthy threat of cancer and triggers an attack of killer T cells custom-made to destroy the tumors, scientists report. Fri, 30 Oct 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/10/091029125534.htm http://www.sciencedaily.com/releases/2009/10/091026162548.htm In a recent study of possible triggers of cancer among northern New England residents, epidemiologists identified an enhanced risk to the bladders of patients taking drugs that suppress the immune system. Tue, 27 Oct 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/10/091026162548.htm http://www.sciencedaily.com/releases/2009/09/090930132658.htm Researchers have put an end to a 10-year debate over which form of a molecular messenger called Fas ligand is responsible for killing cells during programmed cell death (also called apoptosis). Tue, 27 Oct 2009 02:00:00 EDT http://www.sciencedaily.com/releases/2009/09/090930132658.htm http://www.sciencedaily.com/releases/2009/10/091021133849.htm A new study by cancer researchers shows for the first time that the loss of a gene called PTEN from a type of normal cell in breast tumors can dramatically change the environment within the tumor in ways that foster the tumor's growth. Wed, 21 Oct 2009 17:00:00 EDT http://www.sciencedaily.com/releases/2009/10/091021133849.htm http://www.sciencedaily.com/releases/2009/10/091012225543.htm Scientists say that studying pet dogs with cancer could yield valuable information on how to diagnose and treat human cancers. Tue, 20 Oct 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/10/091012225543.htm http://www.sciencedaily.com/releases/2009/10/091018141723.htm Researchers have identified that Rituxan, a drug previously approved for the treatment of non-Hodgkin's B cell lymphoma and rheumatoid arthritis, can treat severe ANCA-associated vasculitis as effectively as cyclophosphamide, the current standard therapy. Sat, 17 Oct 2009 00:00:00 EDT http://www.sciencedaily.com/releases/2009/10/091018141723.htm http://www.sciencedaily.com/releases/2009/10/091013110048.htm Researchers have uncovered a large, new cache of genes that act as built-in barriers against cancer. Known as tumor suppressors, the newly identified genes and the insight that they provide into devising new therapeutic strategies against lymphoma are described in a new paper. Wed, 14 Oct 2009 20:00:00 EDT http://www.sciencedaily.com/releases/2009/10/091013110048.htm http://www.sciencedaily.com/releases/2009/10/091010120627.htm Scientists have demonstrated that misregulation of the protein SPAK may contribute to B-cell lymphoma development. Sat, 10 Oct 2009 00:00:00 EDT http://www.sciencedaily.com/releases/2009/10/091010120627.htm http://www.sciencedaily.com/releases/2009/09/090921134823.htm An investigative drug deprived non-Hodgkin lymphoma cells of their ability to survive too long and multiply too fast, according to an early study. Sun, 04 Oct 2009 17:00:00 EDT http://www.sciencedaily.com/releases/2009/09/090921134823.htm http://www.sciencedaily.com/releases/2009/09/090930102721.htm Acute lymphatic leukemia is the most common form of blood cancer in children. Even though chemotherapy is improving, the cancer often returns. New research shows that cancer cells that have been exposed to chemotherapy and survived are less vulnerable to chemotherapy, and more aggressive as well. But this research also yielded discoveries that should be able to enhance our treatment of the disease. Thu, 01 Oct 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/09/090930102721.htm http://www.sciencedaily.com/releases/2009/09/090925101957.htm Researchers have found that non-AIDS-defining malignancies such as anal and lung cancer have become more prevalent among HIV-infected patients than non-HIV patients since the introduction of anti-retroviral therapies in the mid-1990s. Mon, 28 Sep 2009 11:00:00 EDT http://www.sciencedaily.com/releases/2009/09/090925101957.htm http://www.sciencedaily.com/releases/2009/09/090907162310.htm In a finding with potentially major implications for identifying a viral cause of prostate cancer, researchers have reported that a type of virus known to cause leukemia and sarcomas in animals has been found for the first time in malignant human prostate cancer cells. Tue, 08 Sep 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/09/090907162310.htm http://www.sciencedaily.com/releases/2009/08/090824204116.htm A study of 7,689 admissions from 178 adult intensive care units in England, Wales and Northern Ireland has revealed the factors associated with a higher mortality rate in hematological malignancy. Researchers found that certain factors have a significant impact on the risk of death. Wed, 02 Sep 2009 23:00:00 EDT http://www.sciencedaily.com/releases/2009/08/090824204116.htm http://www.sciencedaily.com/releases/2009/07/090720163546.htm Surgically removing and evaluating an increasing number of lymph nodes does not appear to identify a greater number of patients with stage III colorectal cancer, according to a new report. Wed, 26 Aug 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090720163546.htm http://www.sciencedaily.com/releases/2009/08/090824151302.htm Two of the most powerful approaches to cancer treatment -- a stem cell transplant and an immune system-stimulating vaccine -- appear to reinforce each other in patients with an aggressive, hard-to-control form of leukemia, scientists have found. Tue, 25 Aug 2009 17:00:00 EDT http://www.sciencedaily.com/releases/2009/08/090824151302.htm http://www.sciencedaily.com/releases/2009/08/090824081115.htm A new analysis has found that adolescents and young adults who were recently diagnosed with blood-related cancers have better long-term survival rates than those who were diagnosed in the 1980s. Tue, 25 Aug 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/08/090824081115.htm http://www.sciencedaily.com/releases/2009/08/090820124127.htm Researchers have developed a new way to split up a dangerous pair of cancer proteins, a finding that could ultimately lead to chemotherapy that is more effective and has fewer side effects. Mon, 24 Aug 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/08/090820124127.htm http://www.sciencedaily.com/releases/2009/07/090730180225.htm The incidence of a rare and deadly tumor called primary central nervous system lymphoma (PCNSL) is two times higher in black Americans, ages 20 to 49, than in white Americans, according to a new study. Wed, 19 Aug 2009 23:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090730180225.htm http://www.sciencedaily.com/releases/2009/08/090803122719.htm Researchers studying an enzyme believed to play a role in allergy onset, instead have discovered its previously unknown role as a tumor suppressor that may be important in myeloproliferative diseases and some types of lymphoma and leukemia. Myeloproliferative diseases are a group of disorders characterized by an overproduction of blood cells by the bone marrow and include chronic myeloid leukemia. Lymphoma and leukemia are cancers of the blood. Wed, 12 Aug 2009 20:00:00 EDT http://www.sciencedaily.com/releases/2009/08/090803122719.htm http://www.sciencedaily.com/releases/2009/08/090805164919.htm A new study shows that certain genes are turned off early in the development of chronic lymphocytic leukemia (CLL), before clinical signs of the disease appear. The study examined cancer cells from CLL patients and from a new strain of mice that develops a very similar disease. The findings suggest that epigenetic alterations might serve as markers for detecting CLL early and for monitoring progression, and that their reversal might delay or prevent progression. Fri, 07 Aug 2009 20:00:00 EDT http://www.sciencedaily.com/releases/2009/08/090805164919.htm http://www.sciencedaily.com/releases/2009/07/090730182705.htm Lymphoma and other cancers may occur when a delicate gene recombination process in antibody-making cells goes awry, according to preliminary studies in mice at the University of Michigan. Thu, 06 Aug 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090730182705.htm http://www.sciencedaily.com/releases/2009/07/090728102308.htm DLX5, a gene crucial for embryonic development, promotes cancer by activating the expression of the known oncogene, MYC, according to researchers. Since the DLX5 gene is inactive in normal adults, it may be an ideal target for future anti-cancer drugs, they reason. Wed, 05 Aug 2009 20:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090728102308.htm http://www.sciencedaily.com/releases/2009/07/090723150830.htm Expression of a single gene programs an immune system helper T cell that fuels rapid growth and diversification of antibodies in a cellular structure implicated in autoimmune diseases and development of B cell lymphoma, scientists report in Science. Wed, 05 Aug 2009 02:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090723150830.htm http://www.sciencedaily.com/releases/2009/07/090727110641.htm Distinctive patterns of genes turned off -- or left on -- in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them scientists say. Tue, 28 Jul 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090727110641.htm http://www.sciencedaily.com/releases/2009/06/090624210847.htm Scientists have identified a stromal marker for breast cancer progression.  Sun, 26 Jul 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090624210847.htm http://www.sciencedaily.com/releases/2009/07/090720134232.htm Carriers have nearly twice the risk of developing follicular lymphoma, according to cancer's first genome-wide association study. Tue, 21 Jul 2009 02:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090720134232.htm http://www.sciencedaily.com/releases/2009/07/090713160521.htm A new chemotherapy regimen for pediatric Hodgkin's lymphoma patients has been identified. The new treatment enhances efficacy through dose-dense drug delivery while simultaneously reducing the long-term risks presented by high cumulative dose chemotherapy. Fri, 17 Jul 2009 11:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090713160521.htm http://www.sciencedaily.com/releases/2009/06/090629200626.htm A recent study focuses on the intersection of these two scientific puzzles, resulting in new discoveries about how one herpes virus known to cause cancer may reactivate when the infected cell senses another type of virus entering it. Tue, 30 Jun 2009 11:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090629200626.htm http://www.sciencedaily.com/releases/2009/06/090612092743.htm Researchers have identified a key mechanism that causes chromosomes within blood cells to break -- an occurrence that marks the first step in the development of human lymphoma. Tue, 30 Jun 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090612092743.htm http://www.sciencedaily.com/releases/2009/06/090617161500.htm Patients treated for Hodgkin lymphoma with radiation therapy have a substantially higher risk of stroke, according to a new study. Thu, 25 Jun 2009 23:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090617161500.htm http://www.sciencedaily.com/releases/2009/06/090624161636.htm Effective drugs for treating a chemotherapy-resistant form of lymphoma might already be on the market according to a study that has pieced together a chemical pathway involved in the disease. By following the trail of several molecular flags that mark this type of cancer, researchers have discovered that anti-inflammatory drugs used to treat arthritis will shrink lymphoma tumors in mice. Thu, 25 Jun 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090624161636.htm http://www.sciencedaily.com/releases/2009/06/090613064344.htm Research has shown for the first time how cancers that spread to the brain establish themselves and begin to grow. Mon, 22 Jun 2009 11:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090613064344.htm http://www.sciencedaily.com/releases/2009/06/090617131402.htm Scientists have uncovered clues to the development of cancers in AIDS patients. Thu, 18 Jun 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090617131402.htm http://www.sciencedaily.com/releases/2009/06/090612092739.htm A single gene can control growth in cancers related to the Epstein-Barr virus and that existing therapeutics can inactivate it, according to new research. Wed, 17 Jun 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090612092739.htm http://www.sciencedaily.com/releases/2009/06/090610133455.htm Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells. Their study suggests that blocking this fatty infiltration could help enhance patients' recovery after transplant. Mon, 15 Jun 2009 02:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090610133455.htm http://www.sciencedaily.com/releases/2009/06/090611160658.htm Investigators have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy -- a process in which cancer cells eat themselves. Sat, 13 Jun 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090611160658.htm http://www.sciencedaily.com/releases/2009/06/090601140930.htm Stem cell researchers have shown that a protein that keeps embryonic stem cells in their stem-like state, called LIN28, is also important in cancer. It offers a new target to attack, especially in resistant and hard-to-treat cases. Mon, 08 Jun 2009 11:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090601140930.htm http://www.sciencedaily.com/releases/2009/05/090527181540.htm Scientist have announced encouraging results for an experimental therapy using elements of the body's immune system to improve cure rates for children with neuroblastoma, a challenging cancer of the nervous system. Children who received monoclonal antibodies and cytokines were 20 percent more likely to be living disease-free two years after treatment, compared to children receiving standard therapy. Thu, 28 May 2009 23:00:00 EDT http://www.sciencedaily.com/releases/2009/05/090527181540.htm http://www.sciencedaily.com/releases/2009/05/090527181544.htm Focusing HIV drug development on immune cells called macrophages could help combat the disease, according to new research. Thu, 28 May 2009 17:00:00 EDT http://www.sciencedaily.com/releases/2009/05/090527181544.htm