http://www.sciencedaily.com/news/health_medicine/malaria/ Malaria research. Read the latest medical research on malaria, including new control methods and malaria treatments. en-us Sat, 26 May 2012 13:05:01 EDT Sat, 26 May 2012 13:05:01 EDT 60 http://www.sciencedaily.com/images/logosmall.gif http://www.sciencedaily.com/news/health_medicine/malaria/ For more science articles, visit ScienceDaily. http://www.sciencedaily.com/releases/2012/05/120523115049.htm Scientists are reporting development of a new, higher-yield, two-step, less costly process that may ease supply problems and zigzagging prices for the raw material essential for making the mainstay drug for malaria. That disease sickens 300-500 million people annually and kills more than one million. The report on the process uses readily available substances and could be easily implemented by drug companies. Wed, 23 May 2012 11:50:50 EDT http://www.sciencedaily.com/releases/2012/05/120523115049.htm http://www.sciencedaily.com/releases/2012/05/120521164058.htm Researchers have uncovered new knowledge related to host-parasite interaction in severe malaria, concerning how malaria parasites are able to bind to cells in the brain and cause cerebral malaria -- the most lethal form of the disease. Mon, 21 May 2012 16:40:40 EDT http://www.sciencedaily.com/releases/2012/05/120521164058.htm http://www.sciencedaily.com/releases/2012/05/120521103819.htm Researchers have discovered a novel mechanism regulating the development of breast cancer bone metastases and showed that heparin-like compounds can potentially be used to inhibit breast cancer metastasis to bone. Mon, 21 May 2012 10:38:38 EDT http://www.sciencedaily.com/releases/2012/05/120521103819.htm http://www.sciencedaily.com/releases/2012/05/120516174437.htm Biologists have succeeded in engineering algae to produce potential candidates for a vaccine that would prevent transmission of the parasite that causes malaria. Wed, 16 May 2012 17:44:44 EDT http://www.sciencedaily.com/releases/2012/05/120516174437.htm http://www.sciencedaily.com/releases/2012/05/120508152046.htm A scientist and designer from Africa have together created a fashionable hooded bodysuit embedded at the molecular level with insecticides for warding off mosquitoes infected with malaria. The outfit debuted on the runway at the Cornell Fashion Collective spring fashion show, April 28. Tue, 08 May 2012 15:20:20 EDT http://www.sciencedaily.com/releases/2012/05/120508152046.htm http://www.sciencedaily.com/releases/2012/05/120507102328.htm Scientists have developed a larval rearing unit based on a tray and rack system that is expected to be able to successfully rear rear 140,000–175,000 adult mosquitoes per rack. Mon, 07 May 2012 10:23:23 EDT http://www.sciencedaily.com/releases/2012/05/120507102328.htm http://www.sciencedaily.com/releases/2012/04/120427095959.htm Scientists have identified genetic mutations in the deadliest malaria parasite in Africa that are giving it resistance to one of the most powerful anti-malarial drugs. The researchers say their findings are a further warning that the best weapons against malaria could become obsolete. Fri, 27 Apr 2012 09:59:59 EDT http://www.sciencedaily.com/releases/2012/04/120427095959.htm http://www.sciencedaily.com/releases/2012/04/120420105833.htm Scientists have identified a link between different strains of malaria parasites that cause severe disease, which could help develop vaccines or drugs against life-threatening cases of the infection. Fri, 20 Apr 2012 10:58:58 EDT http://www.sciencedaily.com/releases/2012/04/120420105833.htm http://www.sciencedaily.com/releases/2012/04/120408150543.htm The most deadly species of malaria parasite, Plasmodium falciparum, is becoming resistant to the front line treatment for malaria on the border of Thailand and Myanmar, according to new evidence. This increases concern that resistance could now spread to India and then Africa. Eliminating malaria might then prove impossible. Sun, 08 Apr 2012 15:05:05 EDT http://www.sciencedaily.com/releases/2012/04/120408150543.htm http://www.sciencedaily.com/releases/2012/04/120405144240.htm Researchers have developed a "gene chip" to contribute to the identification of malaria drug resistance, an effort that will allow for real-time response in modified treatment strategies for this devastating disease. Thu, 05 Apr 2012 14:42:42 EDT http://www.sciencedaily.com/releases/2012/04/120405144240.htm http://www.sciencedaily.com/releases/2012/04/120402162553.htm A drug candidate that has shown promise for neutralizing dangerous bacteria also prevents the parasite that causes malaria from growing, new research shows. Mon, 02 Apr 2012 16:25:25 EDT http://www.sciencedaily.com/releases/2012/04/120402162553.htm http://www.sciencedaily.com/releases/2012/04/120402112927.htm Malaria infections among infants can be cut by up to 30 percent when antimalarial drugs are given intermittently over a 12-month period, a three-year clinical trial in Papua New Guinea has shown. Mon, 02 Apr 2012 11:29:29 EDT http://www.sciencedaily.com/releases/2012/04/120402112927.htm http://www.sciencedaily.com/releases/2012/02/120227204919.htm A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against many other parasitic protozoa, the drug readily crosses into the red blood cells of malaria-infected mice and kills the malaria parasite. The drug works at very low concentrations with no observed toxicity to the mouse. Mon, 27 Feb 2012 20:49:49 EST http://www.sciencedaily.com/releases/2012/02/120227204919.htm http://www.sciencedaily.com/releases/2012/02/120214100940.htm New research shows how the malaria parasite changes into a banana shape before sexual reproduction, a finding that could provide targets for vaccine or drug development and may explain how the parasite evades the human immune system. Tue, 14 Feb 2012 10:09:09 EST http://www.sciencedaily.com/releases/2012/02/120214100940.htm http://www.sciencedaily.com/releases/2012/02/120209172808.htm A study of almost 3,800 pregnancies has provided the most accurate and direct evidence to date that malaria infection reduces early fetal growth. Low birth weight is the most important risk factor for neonatal mortality in developing countries. The research, carried out on the border of Thailand and Myanmar, highlights the importance of preventing malaria in pregnancy. Thu, 09 Feb 2012 17:28:28 EST http://www.sciencedaily.com/releases/2012/02/120209172808.htm http://www.sciencedaily.com/releases/2012/02/120208220215.htm A species of mosquito has been discovered breeding in the UK that has not been seen in the country since 1945. Populations of the mosquito, found across mainland Europe and known only by its Latin name Culex modestus, were recorded at a number of sites in the marshes of north Kent and south Essex in 2010 and 2011. Wed, 08 Feb 2012 22:02:02 EST http://www.sciencedaily.com/releases/2012/02/120208220215.htm http://www.sciencedaily.com/releases/2012/02/120206092635.htm A new analysis demonstrates that confronting several diseases at once is a viable way to make the most of thinly stretched donor dollars and national health care budgets, and help save more lives. Mon, 06 Feb 2012 09:26:26 EST http://www.sciencedaily.com/releases/2012/02/120206092635.htm http://www.sciencedaily.com/releases/2012/02/120203141505.htm Refugee children have scant access to medical care and are particularly vulnerable to disease. New research from Denmark show that just a few hours of schooling a week may have a pronounced positive impact on their health not only in childhood but later in life when they achieve adulthood. Fri, 03 Feb 2012 14:15:15 EST http://www.sciencedaily.com/releases/2012/02/120203141505.htm http://www.sciencedaily.com/releases/2012/02/120202201740.htm Malaria is killing more people worldwide than previously thought -- 1.2 million -- but the number of deaths has fallen rapidly as efforts to combat the disease have ramped up, according to new research. Researchers say that deaths from malaria have been missed by previous studies because of the assumption that the disease mainly kills children under age five. Thu, 02 Feb 2012 20:17:17 EST http://www.sciencedaily.com/releases/2012/02/120202201740.htm http://www.sciencedaily.com/releases/2012/01/120127135945.htm New research could lead to the design of more effective drugs to combat malaria. The research will enable scientists to learn more about the nature of the enzymes required for vitamin biosynthesis by the malaria causing pathogen Plasmodium. Vitamins are essential nutrients required in small amounts, the lack of which leads to deficiencies. Many pathogenic microorganisms produce vitamins, and these biosynthetic pathways may provide suitable targets for development of new drugs. Fri, 27 Jan 2012 13:59:59 EST http://www.sciencedaily.com/releases/2012/01/120127135945.htm http://www.sciencedaily.com/releases/2012/01/120125113151.htm Researchers have devised a technique to overcome a genetic oddity of Plasmodium falciparum, the major cause of human malaria, which has stymied research into the organism's genes. The technique opens the door to genetic discovery for the entire organism, which should foster a greater understanding of the parasite, and facilitate discovery of new medications for a disease that infects 200 million people and kills nearly 700,000 every year. Wed, 25 Jan 2012 11:31:31 EST http://www.sciencedaily.com/releases/2012/01/120125113151.htm http://www.sciencedaily.com/releases/2012/01/120120184532.htm Researchers have made a fundamental discovery in understanding how malaria parasites cause deadly disease. The researchers show how parasites target proteins to the surface of the red blood cell that enables sticking to and blocking blood vessels. Strategies that prevent this host-targeting process will block disease. Fri, 20 Jan 2012 18:45:45 EST http://www.sciencedaily.com/releases/2012/01/120120184532.htm http://www.sciencedaily.com/releases/2012/01/120118123050.htm Scientists have discovered a molecule that is key to malaria's 'invisibility cloak.' The research will help to better understand how the parasite causes disease and escapes from the defenses mounted by the immune system. Wed, 18 Jan 2012 12:30:30 EST http://www.sciencedaily.com/releases/2012/01/120118123050.htm http://www.sciencedaily.com/releases/2012/01/120117143737.htm In the future it should be possible to produce the best anti-malaria drug, artemisinin, more economically and in sufficient volumes for all patients. Tue, 17 Jan 2012 14:37:37 EST http://www.sciencedaily.com/releases/2012/01/120117143737.htm http://www.sciencedaily.com/releases/2012/01/120112142224.htm Genome sequencing leads to the identification of a protein crucial to the work of two parasites as they spread a pair of deadly diseases, toxoplasmosis and malaria. Thu, 12 Jan 2012 14:22:22 EST http://www.sciencedaily.com/releases/2012/01/120112142224.htm http://www.sciencedaily.com/releases/2012/01/120110114533.htm Virginia Tech researchers have identified a novel anti-viral pathway in the immune system of culicine mosquitoes, the insect family to which mosquitoes that spread yellow fever, West Nile fever, dengue fever, and chikungunya fever belong. Tue, 10 Jan 2012 11:45:45 EST http://www.sciencedaily.com/releases/2012/01/120110114533.htm http://www.sciencedaily.com/releases/2012/01/120107151849.htm A biology lab has successfully cracked the structure of an enzyme made by Plasmodium falciparum, the parasitical protozoan that causes the most lethal form of malaria. Plasmodium cannot live without the enzyme, which is uses to make cell membrane. Because people don't make this enzyme, it is an ideal target for an anti-malarial drug. Such a drug might kill Plasmodium but have minimal side effects for people. Sat, 07 Jan 2012 15:18:18 EST http://www.sciencedaily.com/releases/2012/01/120107151849.htm http://www.sciencedaily.com/releases/2012/01/120105111946.htm Researchers have demonstrated for the first time that the Anopheles mosquito’s innate immune system could be genetically engineered to block the transmission of the malaria-causing parasite to humans. In addition, they showed that the genetic modification had little impact on the mosquito’s fitness under laboratory conditions. Thu, 05 Jan 2012 11:19:19 EST http://www.sciencedaily.com/releases/2012/01/120105111946.htm http://www.sciencedaily.com/releases/2011/12/111229091845.htm The microbes on your skin determine how attractive you are to mosquitoes, which may have important implications for malaria transmission and prevention, according to a new study. Thu, 29 Dec 2011 09:18:18 EST http://www.sciencedaily.com/releases/2011/12/111229091845.htm http://www.sciencedaily.com/releases/2011/12/111220133701.htm A new candidate malaria vaccine has the potential to neutralize all strains of the most deadly species of malaria parasite. Tue, 20 Dec 2011 13:37:37 EST http://www.sciencedaily.com/releases/2011/12/111220133701.htm http://www.sciencedaily.com/releases/2011/12/111218150258.htm The link between malaria and Salmonella infections has been explained for the first time, opening the way to more effective treatments. Sun, 18 Dec 2011 15:02:02 EST http://www.sciencedaily.com/releases/2011/12/111218150258.htm http://www.sciencedaily.com/releases/2011/12/111212220956.htm The largest ever study to assess the effects of malaria and its treatment in the first trimester of pregnancy has shown that the disease significantly increases the risk of miscarriage, but that treating with antimalarial drugs is relatively safe and reduces this risk. Mon, 12 Dec 2011 22:09:09 EST http://www.sciencedaily.com/releases/2011/12/111212220956.htm http://www.sciencedaily.com/releases/2011/12/111212124608.htm Researchers have discovered how malaria manipulates the immune system to allow the parasite to persist in the bloodstream. By rescuing this immune system pathway, the research team was able to cure mice of bloodstream malaria infections. Mon, 12 Dec 2011 12:46:46 EST http://www.sciencedaily.com/releases/2011/12/111212124608.htm http://www.sciencedaily.com/releases/2011/12/111212092655.htm Seabirds often live in large colonies in very confined spaces. Parasites, such as fleas and ticks, take advantage of this ideal habitat with its rich supply of nutrition. As a result, they can transmit blood parasites like avian malaria to the birds. Scientists have investigated whether this affects all seabirds equally, and whether climate conditions, the habitat or particular living conditions influence infection with avian malaria. They discovered that most seabirds are free of malaria parasites; however, some groups, especially frigatebirds, are particularly common hosts to malaria parasites. Mon, 12 Dec 2011 09:26:26 EST http://www.sciencedaily.com/releases/2011/12/111212092655.htm http://www.sciencedaily.com/releases/2011/12/111207152416.htm An antimalarial agent proved effective at clearing infections caused by the malaria parasite most lethal to humans -- by literally starving the parasites to death. Wed, 07 Dec 2011 15:24:24 EST http://www.sciencedaily.com/releases/2011/12/111207152416.htm http://www.sciencedaily.com/releases/2011/12/111205102704.htm Researchers have unraveled the mystery as to how the malaria mosquito uses its sensory powers to find food and spread disease. Mon, 05 Dec 2011 10:27:27 EST http://www.sciencedaily.com/releases/2011/12/111205102704.htm http://www.sciencedaily.com/releases/2011/12/111201105403.htm A mutation on the surface of human red blood cells provides protection against malaria caused by the parasite Plasmodium vivax, new research shows. The investigators found the change makes it harder for the parasite to lock onto the cell and gain entry. Thu, 01 Dec 2011 10:54:54 EST http://www.sciencedaily.com/releases/2011/12/111201105403.htm http://www.sciencedaily.com/releases/2011/11/111119153527.htm IBM's Watson computing system broke new ground earlier this year when it defeated two celebrated human competitors on the Jeopardy! game show. Now, The Scripps Research Institute is hoping to do something equally novel but more critical to human health with part of the prize money from that tournament: Find a cure for drug-resistant malaria. And it's asking for the public's help. Sat, 19 Nov 2011 15:35:35 EST http://www.sciencedaily.com/releases/2011/11/111119153527.htm http://www.sciencedaily.com/releases/2011/11/111118133044.htm Why do people with a hereditary mutation of the red blood pigment hemoglobin (as is the case with sickle-cell anemia prevalent in Africa) not contract severe malaria? Scientists have now solved this mystery. Fri, 18 Nov 2011 13:30:30 EST http://www.sciencedaily.com/releases/2011/11/111118133044.htm http://www.sciencedaily.com/releases/2011/11/111117154637.htm Researchers have discovered a group of chemical compounds that might one day be developed into drugs that can treat malaria infection in both the liver and the bloodstream. Thu, 17 Nov 2011 15:46:46 EST http://www.sciencedaily.com/releases/2011/11/111117154637.htm http://www.sciencedaily.com/releases/2011/11/111117143957.htm The discovery of a new class of dual-acting antimalarial compounds that target both liver and blood infections, attacking the Plasmodium parasite at both stages in its reproduction cycle, to publish. Scientists developed a novel assay to determine liver stage activity of candidate small molecules, then used the assay and other tools to identify and optimize a chemical scaffold with activity on both blood- and liver-stage parasites in malaria mouse models. Thu, 17 Nov 2011 14:39:39 EST http://www.sciencedaily.com/releases/2011/11/111117143957.htm http://www.sciencedaily.com/releases/2011/11/111117135722.htm Scientists have discovered a family of chemical compounds that could lead to a new generation of antimalarial drugs capable of not only alleviating symptoms but also preventing the deadly disease. Thu, 17 Nov 2011 13:57:57 EST http://www.sciencedaily.com/releases/2011/11/111117135722.htm http://www.sciencedaily.com/releases/2011/11/111115175805.htm A study detected contrasting patterns of drug resistance in malaria-causing parasites taken from both humans and mosquitoes. Parasites found in human blood samples showed a high prevalence for pyrimethamine-resistance, which was consistent with the class of drugs widely used to treat malaria. However, parasites taken from mosquitoes themselves had very low prevalence of pyrimethamine-resistance and a high prevalence of cycloguanil-resistant mutants indicating resistance to a newer class of antimalaria drug not widely used in Zambia. Tue, 15 Nov 2011 17:58:58 EST http://www.sciencedaily.com/releases/2011/11/111115175805.htm http://www.sciencedaily.com/releases/2011/11/111102125650.htm One of the most comprehensive analyses yet done of the ancient history of insect-borne disease concludes for the first time that malaria is not only native to the New World, but it has been present long before humans existed and has evolved through birds and monkeys. Wed, 02 Nov 2011 12:56:56 EDT http://www.sciencedaily.com/releases/2011/11/111102125650.htm http://www.sciencedaily.com/releases/2011/11/111102082725.htm With a new, poison-free approach to malaria control, researchers in the Solarmal project have expressed not only the hope to eliminate malaria in Africa at local level, but also to provide the local population with a source of sustainable energy. Wed, 02 Nov 2011 08:27:27 EDT http://www.sciencedaily.com/releases/2011/11/111102082725.htm http://www.sciencedaily.com/releases/2011/11/111101095400.htm A new research technology is revealing how humans develop immunity to malaria, and could assist programs aimed at eradicating this parasitic disease. Tue, 01 Nov 2011 09:54:54 EDT http://www.sciencedaily.com/releases/2011/11/111101095400.htm http://www.sciencedaily.com/releases/2011/10/111028113629.htm Scientists have found a deadly parasite with some of its chromosomes in duplicate, others in triplicate, while still others are present four or even five times. Moreover, the copy number varies between individuals. Such a bizarre occurrence has never before been found in nature, in any organism. As a rule, chromosomes should come in couples. Scientists made the striking discovery while deciphering the genetic code of a series of Leishmania parasites. Fri, 28 Oct 2011 11:36:36 EDT http://www.sciencedaily.com/releases/2011/10/111028113629.htm http://www.sciencedaily.com/releases/2011/10/111028082119.htm After a significant fall in malaria in Africa over recent years, the disease is making a disquieting return. The deployment of new, highly effective treatments and distribution of millions of insecticide treated bednets have helped check this terrible disease’s progress. However, scientists have observed a new leap in the number of cases since the end of 2010 in the village of Dielmo, Senegal. Fri, 28 Oct 2011 08:21:21 EDT http://www.sciencedaily.com/releases/2011/10/111028082119.htm http://www.sciencedaily.com/releases/2011/10/111026175331.htm A new malaria vaccine could be the first to tackle different forms of the disease and help those most vulnerable to infection, a study suggests. Wed, 26 Oct 2011 17:53:53 EDT http://www.sciencedaily.com/releases/2011/10/111026175331.htm http://www.sciencedaily.com/releases/2011/10/111025102326.htm Researchers have shown for the first time in a rodent model that the earliest form of malaria parasites can lay dormant in red blood cells and "wake up," or recover, following treatment with the antimalarial drug artesunate. Tue, 25 Oct 2011 10:23:23 EDT http://www.sciencedaily.com/releases/2011/10/111025102326.htm http://www.sciencedaily.com/releases/2011/10/111020145050.htm After its initial appearance in New York in 1999, West Nile virus spread across the United States in just a few years and is now well established throughout North and South America. Researchers have found that in most places only a few key species of bird "hosts" and mosquito "vectors" are important in transmission of the virus. Thu, 20 Oct 2011 14:50:50 EDT http://www.sciencedaily.com/releases/2011/10/111020145050.htm http://www.sciencedaily.com/releases/2011/10/111018131334.htm First results from a large-scale Phase III trial of RTS,S* show the malaria vaccine candidate to provide young African children with significant protection against clinical and severe malaria with an acceptable safety and tolerability profile. Tue, 18 Oct 2011 13:13:13 EDT http://www.sciencedaily.com/releases/2011/10/111018131334.htm http://www.sciencedaily.com/releases/2011/10/111012124158.htm A new study could lead to improved gene therapies for conditions such as heart disease and cancer as well as more effective vaccines for tuberculosis, malaria and other diseases. Wed, 12 Oct 2011 12:41:41 EDT http://www.sciencedaily.com/releases/2011/10/111012124158.htm http://www.sciencedaily.com/releases/2011/10/111005172635.htm Indoor spraying with the insecticide bendiocarb has dramatically decreased malaria transmission in many parts of Benin, new evidence that insecticides remain a potent weapon for fighting malaria in Africa despite the rapid rise of resistance to an entire class of mosquito-killing compounds, according to a new study. Wed, 05 Oct 2011 17:26:26 EDT http://www.sciencedaily.com/releases/2011/10/111005172635.htm http://www.sciencedaily.com/releases/2011/10/111003151832.htm Researchers have discovered a new function for an enzyme that may protect against organ injury and death from anemia. Mon, 03 Oct 2011 15:18:18 EDT http://www.sciencedaily.com/releases/2011/10/111003151832.htm http://www.sciencedaily.com/releases/2011/09/110927183544.htm Central Asia continues to suffer from a post-Soviet economic breakdown that may have contributed to a re-emergence of several neglected tropical diseases in the area, especially among its most economically disadvantaged groups, according to a new article. Tue, 27 Sep 2011 18:35:35 EDT http://www.sciencedaily.com/releases/2011/09/110927183544.htm http://www.sciencedaily.com/releases/2011/09/110927112417.htm Researchers have validated that two enzymes used by malaria parasites to chew up human hemoglobin are potential anti-malarial drug targets. Tue, 27 Sep 2011 11:24:24 EDT http://www.sciencedaily.com/releases/2011/09/110927112417.htm http://www.sciencedaily.com/releases/2011/09/110926131810.htm Continuing a global effort to prevent malaria infections, researchers have now created a new malaria vaccine -- one that combines the use of a disabled cold virus with an immune system-stimulating gene -- that appears to increase the immune response against the parasite that causes the deadly disease. Mon, 26 Sep 2011 13:18:18 EDT http://www.sciencedaily.com/releases/2011/09/110926131810.htm http://www.sciencedaily.com/releases/2011/09/110926081908.htm A recent article shows a link between changes in the malaria parasite and the absorption of pharmaceutical compounds. Increased knowledge of the malaria parasite and the connection with the development of resistance may contribute to the development of new malaria treatments. Mon, 26 Sep 2011 08:19:19 EDT http://www.sciencedaily.com/releases/2011/09/110926081908.htm http://www.sciencedaily.com/releases/2011/09/110909111451.htm For the first time, a malaria vaccine that uses the entire parasite has proven safe and shown promise to produce a strong immune response in a clinical trial, according to a new study. The vaccine is unique in that it employs the entire malaria parasite. Researchers found that the vaccine could provide unprecedented immune responses when administered intravenously. Fri, 09 Sep 2011 11:14:14 EDT http://www.sciencedaily.com/releases/2011/09/110909111451.htm