http://www.sciencedaily.com/news/health_medicine/ovarian_cancer/ Information about ovarian cancer symptoms and treatments. Explore the latest medical research on ovarian cysts and ovarian cancer including including stages of the disease and new treatment options. en-us Sat, 11 Jul 2009 01:05:01 EDT Sat, 11 Jul 2009 01:05:01 EDT 60 http://www.sciencedaily.com/images/logosmall.gif http://www.sciencedaily.com/news/health_medicine/ovarian_cancer/ For more science articles, visit ScienceDaily. http://www.sciencedaily.com/releases/2009/07/090709072429.htm Researchers found that survival among women with ovarian cancer is influenced by age of menarche and total number of lifetime ovulatory cycles. Thu, 09 Jul 2009 00:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090709072429.htm http://www.sciencedaily.com/releases/2009/07/090701082917.htm Survivors of childhood cancer run particular risks when pregnant and should be closely monitored, say researchers. Although such women may have conceived spontaneously and considered themselves to be perfectly healthy, their deliveries should always take place in a hospital, experts urge. Wed, 08 Jul 2009 23:00:00 EDT http://www.sciencedaily.com/releases/2009/07/090701082917.htm http://www.sciencedaily.com/releases/2009/06/090629081455.htm Ultra-fast freezing of ovarian tissue from women who have lost their fertility as a result of cancer treatment can lead to it being used in transplants with the same success rate as fresh tissue, according to new research. Scientists said that freezing tissue by the vitrification method, which avoids ice formation, meant that oocyte (egg) viability was almost identical with that seen in fresh oocytes. Wed, 08 Jul 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090629081455.htm http://www.sciencedaily.com/releases/2009/06/090629081453.htm A new technique for transplanting the ovaries of women who have lost their fertility has been developed. The new, two-step method of ovarian transplant has produced excellent results in women whose ovaries have been frozen because of cancer treatment. Tue, 30 Jun 2009 14:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090629081453.htm http://www.sciencedaily.com/releases/2009/06/090630075313.htm Women who have a diminished number of eggs in their ovaries, either because they are older or for some other reason such as ovarian surgery, may be more at risk of a trisomic pregnancy than women with an ovarian reserve within the normal, fertile range, researchers have found. Tue, 30 Jun 2009 00:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090630075313.htm http://www.sciencedaily.com/releases/2009/06/090626191301.htm Researchers believe our oldest mammalian relative may help us to better understand ovarian cancer. DNA mapping of the platypus has uncovered an interesting relationship between their sex chromosomes and DNA sequences found in human ovarian cancer. Sat, 27 Jun 2009 17:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090626191301.htm http://www.sciencedaily.com/releases/2009/06/090624210847.htm Scientists have identified a stromal marker for breast cancer progression.  Wed, 24 Jun 2009 00:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090624210847.htm http://www.sciencedaily.com/releases/2009/06/090610185520.htm Scientists have discovered that there appears to be a single spelling mistake in the genetic code of granulosa cell tumors, a rare and often untreatable form of ovarian cancer. The discovery marks the beginning of a new era of cancer genomics. Mon, 22 Jun 2009 11:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090610185520.htm http://www.sciencedaily.com/releases/2009/06/090601182708.htm Researchers have now identified a way to enhance the in vitro anticancer effects of the commonly used platinum-based drug cisplatin and hope that it might be possible to translate these data into the development of a clinical strategy to enhance the anti-cancer effects of platinum-based drugs. Tue, 02 Jun 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/06/090601182708.htm http://www.sciencedaily.com/releases/2009/04/090419133837.htm The addition of a chemotherapeutic drug for leukemia to a standard regimen of two other chemotherapy drugs appears to enhance the response of certain ovarian cancers to treatment, according to a new study. Sat, 25 Apr 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/04/090419133837.htm http://www.sciencedaily.com/releases/2009/04/090419170032.htm Genetic variations in the micro-RNA processing pathway genes and miRNA binding sites predict a woman's risk for developing ovarian cancer and her prospects for survival, researchers report. Thu, 23 Apr 2009 02:00:00 EDT http://www.sciencedaily.com/releases/2009/04/090419170032.htm http://www.sciencedaily.com/releases/2009/04/090416064504.htm A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to new research. Tue, 21 Apr 2009 08:00:00 EDT http://www.sciencedaily.com/releases/2009/04/090416064504.htm http://www.sciencedaily.com/releases/2009/04/090419170025.htm Pancreatic cancer remains one of the deadliest cancers, but researchers may have found a combination therapy to reduce cancer stem cells and stop pancreatic cancer growth. Treatment with gemcitabine and tigatuzumab resulted in the reduction of pancreatic cancer stem cells, caused tumor remission, and significantly increased time-to-tumor progression in 50 percent of treated cases from a median of 54 days to 103 days. Mon, 20 Apr 2009 11:00:00 EDT http://www.sciencedaily.com/releases/2009/04/090419170025.htm http://www.sciencedaily.com/releases/2009/04/090401164043.htm In female cancer patients of reproductive age, radiation treatment directly to the ovaries should be avoided because there is a direct relationship between certain types of radiation therapy and fertility problems, according to a new review. Sun, 12 Apr 2009 17:00:00 EDT http://www.sciencedaily.com/releases/2009/04/090401164043.htm http://www.sciencedaily.com/releases/2009/04/090401181449.htm Screening regimens that combine ultrasound and a blood test for ovarian cancer fail to detect the disease early enough to make important progress, the authors of a new study reported. The combo screening also led to unnecessary surgery, which reinforces the need for a more sensitive and more specific test, said the lead researcher. Sat, 11 Apr 2009 23:00:00 EDT http://www.sciencedaily.com/releases/2009/04/090401181449.htm http://www.sciencedaily.com/releases/2009/03/090324131452.htm The biology of ovarian cancers discovered at an early stage may render them slower growing and less likely to spread than more aggressive cancers, which typically are discovered in an advanced stage, according to a new study. This finding has implications for the question of whether screening for ovarian cancer could save lives. Fri, 27 Mar 2009 05:00:00 EDT http://www.sciencedaily.com/releases/2009/03/090324131452.htm http://www.sciencedaily.com/releases/2009/02/090210162023.htm Researchers have generated altered immune cells that are able to shrink, and in some cases eradicate, large tumors in mice. The immune cells target mesothelin, a protein that is highly expressed, or translated in large amounts from the mesothelin gene, on the surface of several types of cancer cells. The approach shows promise in the development of immunotherapies for certain tumors. Sat, 14 Feb 2009 05:00:00 EST http://www.sciencedaily.com/releases/2009/02/090210162023.htm http://www.sciencedaily.com/releases/2009/02/090205120406.htm Researchers have found that increased angiogenesis, or blood vessel formation, and vascular endothelial growth factor expression are associated with poor survival in women with sex cord-stromal ovarian tumors. Thu, 12 Feb 2009 23:00:00 EST http://www.sciencedaily.com/releases/2009/02/090205120406.htm http://www.sciencedaily.com/releases/2009/02/090205214414.htm The use of fertility drugs does not increase a woman's risk of developing ovarian cancer, finds a large study. Mon, 09 Feb 2009 23:00:00 EST http://www.sciencedaily.com/releases/2009/02/090205214414.htm http://www.sciencedaily.com/releases/2009/02/090202213317.htm A new study identifies molecular pathways associated with outcomes in ovarian cancer. Currently, outcomes following diagnosis of ovarian cancer are very poor, with up to 65-70 percent of women dying within five years of diagnosis. Tue, 03 Feb 2009 17:00:00 EST http://www.sciencedaily.com/releases/2009/02/090202213317.htm http://www.sciencedaily.com/releases/2009/01/090128104704.htm A new study shows no survival difference between premenopausal women with early-stage endometrial cancer whose ovaries were left intact during cancer surgery compared with those whose ovaries were surgically removed. Mon, 02 Feb 2009 08:00:00 EST http://www.sciencedaily.com/releases/2009/01/090128104704.htm http://www.sciencedaily.com/releases/2009/01/090121144057.htm A new study appearing in the Prostate has found that certain measles virus vaccine strain derivatives, including a strain known as MV-CEA, may prove to be an effective treatment for patients with advanced prostate cancer. Fri, 23 Jan 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/01/090121144057.htm http://www.sciencedaily.com/releases/2008/12/081229104706.htm A new study showed that when actual body weight was used in chemo dosing for epithelial ovarian cancer, the overall survival is 40 months for non-obese patients and 47 months for obese patients, not a significant difference. Similar outcomes are seen in obese and non-obese cancer survivors being monitored for recurrence of their ovarian cancer, the study authors said. Earlier studies found obesity as a negative indicator. Wed, 14 Jan 2009 08:00:00 EST http://www.sciencedaily.com/releases/2008/12/081229104706.htm http://www.sciencedaily.com/releases/2009/01/090113174420.htm Prophylactic salpingo-oophorectomy -- removal of the ovaries and fallopian tubes -- reduces the relative risk of breast cancer by approximately 50 percent and the risk of ovarian and fallopian tube cancer by approximately 80 percent in women who carry a mutation in the BRCA1 or BRCA2 gene, researchers report. Tue, 13 Jan 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/01/090113174420.htm http://www.sciencedaily.com/releases/2009/01/090105090841.htm A new epidemiological study has found that among women who have never used menopausal hormone therapy, obese women are at an increased risk of developing ovarian cancer compared with women of normal weight. Tue, 06 Jan 2009 14:00:00 EST http://www.sciencedaily.com/releases/2009/01/090105090841.htm http://www.sciencedaily.com/releases/2009/01/090102124305.htm A tumor-suppressing gene is a key to understanding, and perhaps killing, dormant ovarian cancer cells that persist after initial treatment only to reawaken later, researchers report. They found that expression of ARHI turns on autophagy, or self-eating, in ovarian cancer cells, which promotes their survival in a dormant state. Mon, 05 Jan 2009 20:00:00 EST http://www.sciencedaily.com/releases/2009/01/090102124305.htm http://www.sciencedaily.com/releases/2008/12/081215140934.htm Ovarian cancer cells are "addicted" to a family of proteins produced by the notorious oncogene, MYC, and blocking these Myc proteins halts cell proliferation in the deadliest cancer of the female reproductive system. Wed, 24 Dec 2008 14:00:00 EST http://www.sciencedaily.com/releases/2008/12/081215140934.htm http://www.sciencedaily.com/releases/2008/12/081201233445.htm In a new analysis of tissue biomarkers expressed in ovarian cancer samples, published in PLoS Medicine, David Huntsman and his colleagues from Vancouver General Hospital suggest that substantial differences exist between ovarian cancer subtypes which should be reflected in patient management. Sun, 14 Dec 2008 08:00:00 EST http://www.sciencedaily.com/releases/2008/12/081201233445.htm http://www.sciencedaily.com/releases/2008/12/081203184527.htm Results of a phase III, international randomized clinical trial demonstrate a new standard of care for treating advanced ovarian cancer that significantly reduces side-effects and post-operative deaths compared to the previously established treatment course. The study has a major impact on many countries where the new standard represents a more practical course of treatment. Wed, 03 Dec 2008 00:00:00 EST http://www.sciencedaily.com/releases/2008/12/081203184527.htm http://www.sciencedaily.com/releases/2008/11/081125113114.htm If you're a cancer cell, you want a protein called Bcl-2 on your side because it decides if you live or die. It's usually a trusted bodyguard, protecting cancer cells from programmed death and allowing them to grow and form tumors. But sometimes it turns into their assassin. Scientists knew it happened, but they didn't know how to actually cause such a betrayal. Now they do and it may lead to the development of new cancer-fighting drugs. Mon, 01 Dec 2008 08:00:00 EST http://www.sciencedaily.com/releases/2008/11/081125113114.htm http://www.sciencedaily.com/releases/2008/11/081120173048.htm Confusingly, the cellular process autophagy (essentially self-eating) has been implicated in both cancer cell death and survival. New insight into this paradox has now been provided by work which indicates that the context in which the process occurs determines the outcome. Fri, 28 Nov 2008 02:00:00 EST http://www.sciencedaily.com/releases/2008/11/081120173048.htm http://www.sciencedaily.com/releases/2008/11/081119120159.htm A new class of compounds called phosphaplatins can effectively kill ovarian, testicular, head and neck cancer cells with potentially less toxicity than conventional drugs, according to a new study in the journal Proceedings of the National Academy of Sciences. Thu, 20 Nov 2008 14:00:00 EST http://www.sciencedaily.com/releases/2008/11/081119120159.htm http://www.sciencedaily.com/releases/2008/11/081115083209.htm A protein known to inhibit the growth of ovarian cancer works in part by forcing cancer cells to eat themselves until they die, researchers report in Cancer Research. Tue, 18 Nov 2008 14:00:00 EST http://www.sciencedaily.com/releases/2008/11/081115083209.htm http://www.sciencedaily.com/releases/2008/10/081007192441.htm Women who have had early stage breast cancer surgically removed, and whose tumor cells are stimulated by the hormone estrogen, can benefit from taking luteinizing hormone releasing hormone antagonists, a Cochrane systematic review has concluded. This medication may be taken alone or alongside the use of tamoxifen. Fri, 10 Oct 2008 20:00:00 EDT http://www.sciencedaily.com/releases/2008/10/081007192441.htm http://www.sciencedaily.com/releases/2008/10/081007120429.htm Scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer. The research may lead to new cancer treatments. Fri, 10 Oct 2008 02:00:00 EDT http://www.sciencedaily.com/releases/2008/10/081007120429.htm http://www.sciencedaily.com/releases/2008/09/080923164539.htm Researchers have identified TEM1 as a specific genetic marker for the vascular cells associated with tumor growth, a finding that could aid in diagnosis and treatment of ovarian cancer. Mon, 29 Sep 2008 11:00:00 EDT http://www.sciencedaily.com/releases/2008/09/080923164539.htm http://www.sciencedaily.com/releases/2008/09/080923121952.htm Investigators have achieved a substantial "kill" of pancreatic cancer cells by using nanoparticles to successfully deliver a deadly diphtheria toxin gene. The findings reflect the first time this unique strategy has been tested in pancreatic cancer cells, and the success seen offers promise for future pre-clinical animal studies, and possibly, a new clinical approach. Wed, 24 Sep 2008 20:00:00 EDT http://www.sciencedaily.com/releases/2008/09/080923121952.htm http://www.sciencedaily.com/releases/2008/09/080915083717.htm An investigational drug that combats ovarian cancer by inhibiting the formation of new blood vessels has shown promise in a phase II trial, according to new research. Tue, 16 Sep 2008 02:00:00 EDT http://www.sciencedaily.com/releases/2008/09/080915083717.htm http://www.sciencedaily.com/releases/2008/09/080915083351.htm Women with recurrent ovarian cancer can be helped by an experimental therapy using a drug already touted for its ability to fight other cancers, a finding that provides hope for improved treatment of this deadly disease. Mon, 15 Sep 2008 20:00:00 EDT http://www.sciencedaily.com/releases/2008/09/080915083351.htm http://www.sciencedaily.com/releases/2008/08/080828093351.htm Researchers have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patient. They have shown that when a variant version of a key protein that normally causes cell death is active, patients may be resistant to the cancer-killing drug. Fri, 29 Aug 2008 14:00:00 EDT http://www.sciencedaily.com/releases/2008/08/080828093351.htm http://www.sciencedaily.com/releases/2008/08/080804190645.htm High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian and pancreatic cancers, researchers report in the Proceedings of the National Academy of Sciences. The researchers traced ascorbate's anti-cancer effect to the formation of hydrogen peroxide in the extracellular fluid surrounding the tumors. Normal cells were unaffected. Tue, 05 Aug 2008 17:00:00 EDT http://www.sciencedaily.com/releases/2008/08/080804190645.htm http://www.sciencedaily.com/releases/2008/07/080716101257.htm Scientists have developed a potential new treatment against cancer that attaches magnetic nanoparticles to cancer cells, allowing them to be captured and carried out of the body. The treatment has been tested in the laboratory and will now be looked at in survival studies. Tue, 22 Jul 2008 02:00:00 EDT http://www.sciencedaily.com/releases/2008/07/080716101257.htm http://www.sciencedaily.com/releases/2008/07/080715071412.htm Researchers connect overexpression of tissue type transglutaminase with poor prognosis in ovarian cancer, identify the relevant pathway, and shut TG2 down with an siRNA liposomal nanoparticle. They previously pinpointed TG2's role in resistant and metastatic melanoma and breast and pancreatic cancers. This crucial protein fuels different cancers through different pathways. Thu, 17 Jul 2008 23:00:00 EDT http://www.sciencedaily.com/releases/2008/07/080715071412.htm http://www.sciencedaily.com/releases/2008/07/080707100201.htm Researchers have shown for the first time that it is possible to stimulate a woman's ovaries to produce eggs for collection during the final phase of the menstrual cycle. The finding offers the chance for more women who have been diagnosed with cancer to restore their fertility following chemotherapy or radiotherapy -- cancer treatments that can seriously damage the ovaries, often permanently. Wed, 09 Jul 2008 11:00:00 EDT http://www.sciencedaily.com/releases/2008/07/080707100201.htm http://www.sciencedaily.com/releases/2008/06/080625112310.htm A recently discovered, but not yet understood, section of chromosome 8, called 8q24, may contain at least five distinct regions that are associated with different cancers, according to a study in the June 24 issue of the Journal of the National Cancer Institute. Thu, 26 Jun 2008 20:00:00 EDT http://www.sciencedaily.com/releases/2008/06/080625112310.htm http://www.sciencedaily.com/releases/2008/06/080626090901.htm New research explored whether ovarian cancer has a scent different from other cancers and whether working dogs could be taught to distinguish it in its different stages. Ovarian cancer has a high mortality rate, primarily due to late diagnosis. Researchers found that early-stage and low grade ovarian cancers emit the same scent as advanced tumors. Thu, 26 Jun 2008 14:00:00 EDT http://www.sciencedaily.com/releases/2008/06/080626090901.htm http://www.sciencedaily.com/releases/2008/06/080623092557.htm Women's reports of persistent, recent-onset symptoms linked to ovarian cancer -- abdominal or pelvic pain, difficulty eating or feeling full quickly and abdominal bloating -- when combined with the CA125 blood test may improve the early detection of ovarian cancer by 20 percent. Tue, 24 Jun 2008 02:00:00 EDT http://www.sciencedaily.com/releases/2008/06/080623092557.htm http://www.sciencedaily.com/releases/2008/06/080616115733.htm Combined positron emission tomography and computed tomography scanning of patients in the early stages of ovarian cancer can enable physicians to determine whether the cancer has spread to nearby lymph nodes without having to perform surgery. As a result, unnecessary surgeries could be reduced, which would also lower morbidity rates and postoperative complications for ovarian cancer patients. Mon, 16 Jun 2008 00:00:00 EDT http://www.sciencedaily.com/releases/2008/06/080616115733.htm