http://www.sciencedaily.com/news/health_medicine/ovarian_cancer/ Information about ovarian cancer symptoms and treatments. Explore the latest medical research on ovarian cysts and ovarian cancer including including stages of the disease and new treatment options. en-us Sat, 26 May 2012 13:05:01 EDT Sat, 26 May 2012 13:05:01 EDT 60 http://www.sciencedaily.com/images/logosmall.gif http://www.sciencedaily.com/news/health_medicine/ovarian_cancer/ For more science articles, visit ScienceDaily. http://www.sciencedaily.com/releases/2012/05/120524123201.htm Scientists have developed a compound that enhance cell death in cancer cells. Thu, 24 May 2012 12:32:32 EDT http://www.sciencedaily.com/releases/2012/05/120524123201.htm http://www.sciencedaily.com/releases/2012/04/120403172152.htm Researchers have discovered that blood can help determine the best treatment plan for patients with ovarian cancer. Tue, 03 Apr 2012 17:21:21 EDT http://www.sciencedaily.com/releases/2012/04/120403172152.htm http://www.sciencedaily.com/releases/2012/04/120402094150.htm Stem cells had greater effect than differentiated tumor cells in eliciting antitumor immunity in vivo. Antibodies and T cells targeted cancer stem cells in laboratory models. Data could provide a rationale for a new type of immune therapy. Mon, 02 Apr 2012 09:41:41 EDT http://www.sciencedaily.com/releases/2012/04/120402094150.htm http://www.sciencedaily.com/releases/2012/02/120220102144.htm In a new mouse model that mimics the tumor microenvironment of ovarian cancer, scientists have demonstrated that ovarian tumors don't necessarily break "free" of the immune system, rather dendritic cells of the immune system seem to actively support the tumor's escape. The researchers show that it might be possible to restore the immune system by targeting a patient's own dendritic cells. Mon, 20 Feb 2012 10:21:21 EST http://www.sciencedaily.com/releases/2012/02/120220102144.htm http://www.sciencedaily.com/releases/2012/02/120207133823.htm Genes that are known to be involved in inflammation were found to be related to risk of ovarian cancer. Tue, 07 Feb 2012 13:38:38 EST http://www.sciencedaily.com/releases/2012/02/120207133823.htm http://www.sciencedaily.com/releases/2012/01/120127135444.htm New anti-cancer research has led to the development of a novel class of chemical inhibitors that specifically target cancer cells with pluripotency. Fri, 27 Jan 2012 13:54:54 EST http://www.sciencedaily.com/releases/2012/01/120127135444.htm http://www.sciencedaily.com/releases/2012/01/120124162343.htm Among women with invasive epithelial ovarian cancer, patients having a germline (gene change in a reproductive cell that could be passed to offspring) mutation in the BRCA1 or BRCA2 genes was associated with improved five-year overall survival, with BRCA2 carriers having the best prognosis, according to a new study. Tue, 24 Jan 2012 16:23:23 EST http://www.sciencedaily.com/releases/2012/01/120124162343.htm http://www.sciencedaily.com/releases/2012/01/120113210650.htm A constellation of defective proteins suspected in causing a malfunction in the body's ability to repair its own DNA could be the link scientists need to prove a new class of drugs will be effective in treating a broad range of ovarian cancer patients, a new study found. Fri, 13 Jan 2012 21:06:06 EST http://www.sciencedaily.com/releases/2012/01/120113210650.htm http://www.sciencedaily.com/releases/2012/01/120105161748.htm Pelvic pain and abnormal bleeding aren’t the only signs of gynecologic cancer. Researchers share other symptoms that often are overlooked. Thu, 05 Jan 2012 16:17:17 EST http://www.sciencedaily.com/releases/2012/01/120105161748.htm http://www.sciencedaily.com/releases/2012/01/120104135404.htm The lives of hundreds of women could be saved every year, thanks to a simple online calculator that could help GPs identify women most at risk of having ovarian cancer at a much earlier stage. Wed, 04 Jan 2012 13:54:54 EST http://www.sciencedaily.com/releases/2012/01/120104135404.htm http://www.sciencedaily.com/releases/2011/12/111207133057.htm The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers. Wed, 07 Dec 2011 13:30:30 EST http://www.sciencedaily.com/releases/2011/12/111207133057.htm http://www.sciencedaily.com/releases/2011/12/111205082253.htm Researchers have shown that a tiny genetic variation predicts chances of survival and response to treatment for patients with ovarian cancer. Mon, 05 Dec 2011 08:22:22 EST http://www.sciencedaily.com/releases/2011/12/111205082253.htm http://www.sciencedaily.com/releases/2011/11/111116104524.htm A potential breakthrough in treating late-stage ovarian cancer has come from researchers who have discovered a peptide that shrinks advanced tumors and improves survival rates for this deadly but often undetected disease. Wed, 16 Nov 2011 10:45:45 EST http://www.sciencedaily.com/releases/2011/11/111116104524.htm http://www.sciencedaily.com/releases/2011/11/111108132903.htm Treatment with a recombinant poxviral vaccine showed a positive response in both metastatic breast cancer and ovarian cancer, according to a recent trial. Tue, 08 Nov 2011 13:29:29 EST http://www.sciencedaily.com/releases/2011/11/111108132903.htm http://www.sciencedaily.com/releases/2011/10/111030151549.htm A large pad of abdominal fat cells provides nutrients that promote the spread and growth of ovarian cancer, the fifth leading cause of cancer deaths in women. This fatty tissue, extraordinarily rich in energy-dense lipids, serves as a rich fuel source, enabling cancer cells to multiply rapidly. Sun, 30 Oct 2011 15:15:15 EDT http://www.sciencedaily.com/releases/2011/10/111030151549.htm http://www.sciencedaily.com/releases/2011/10/111011163053.htm Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers report. Tue, 11 Oct 2011 16:30:30 EDT http://www.sciencedaily.com/releases/2011/10/111011163053.htm http://www.sciencedaily.com/releases/2011/10/111011163047.htm Among women with a certain type of high-grade ovarian cancer, having BRCA2 genetic mutations, but not BRCA1, was associated with improved overall survival and improved response to chemotherapy, compared to women with BRCA wild-type (genetic type used as a reference to compare genetic mutations), according to a new study. Tue, 11 Oct 2011 16:30:30 EDT http://www.sciencedaily.com/releases/2011/10/111011163047.htm http://www.sciencedaily.com/releases/2011/09/110920173343.htm Researchers studying ovarian cancer have discovered that, in a substantial fraction of ovarian tumors, a gene closely related to the estrogen receptor is broken and fused to an adjacent gene by a chromosome rearrangement -- a finding that could shed light on how these deadly tumors develop and spread. Identifying a gene fusion in ovarian cancer may provide scientists with a new opportunity to identify ovarian cancers early in their development and perhaps develop new treatments. Tue, 20 Sep 2011 17:33:33 EDT http://www.sciencedaily.com/releases/2011/09/110920173343.htm http://www.sciencedaily.com/releases/2011/09/110919101922.htm Scientists have now deployed a new imaging technology using laser light to detect cancer based on molecular signatures, leading to the localization of even small cancer cell nests that surgeons might otherwise overlook during surgery. The technique has now been successfully tested on nine patients diagnosed with ovarian cancer. There are plans to apply this imaging concept also to minimally invasive and endoscopic procedures. Mon, 19 Sep 2011 10:19:19 EDT http://www.sciencedaily.com/releases/2011/09/110919101922.htm http://www.sciencedaily.com/releases/2011/09/110915163957.htm Ovarian cancer is a rare but often deadly disease that can strike at any time in a woman's life, but researchers have found there are symptoms associated with ovarian cancer that can assist in early detection. Thu, 15 Sep 2011 16:39:39 EDT http://www.sciencedaily.com/releases/2011/09/110915163957.htm http://www.sciencedaily.com/releases/2011/09/110915131645.htm Researchers have identified a molecular pathway that may play a key role in the evolution of chemotherapy resistance. They are hopeful that the discovery may lead to therapies that are tailored to individual patients with ovarian cancer; reversing resistance to chemotherapy and improving survival from the disease. Thu, 15 Sep 2011 13:16:16 EDT http://www.sciencedaily.com/releases/2011/09/110915131645.htm http://www.sciencedaily.com/releases/2011/09/110913103115.htm By combining three previously unrelated imaging tools into one new device, scientists have proposed a new way to diagnose early-stage ovarian cancer in high-risk women through minimally invasive surgery. The new technique may be better than the current standard procedure of preemptively removing the ovaries. Tue, 13 Sep 2011 10:31:31 EDT http://www.sciencedaily.com/releases/2011/09/110913103115.htm http://www.sciencedaily.com/releases/2011/09/110912143508.htm Selectively expressing a cell-killing gene in tumors controls breast cancer stem cells, researchers report. The gene therapy approach, now shown to work in breast, lung, liver, pancreatic and ovarian cancers in animal models, is headed for phase I trial. Mon, 12 Sep 2011 14:35:35 EDT http://www.sciencedaily.com/releases/2011/09/110912143508.htm http://www.sciencedaily.com/releases/2011/09/110906144034.htm Recent approval by the US Food and Drug Administration clears the path for nationwide use of tools that show the greatest specificity in estimating the risk of ovarian cancer in women with a pelvic mass. Tue, 06 Sep 2011 14:40:40 EDT http://www.sciencedaily.com/releases/2011/09/110906144034.htm http://www.sciencedaily.com/releases/2011/09/110903101656.htm Blocking key proteins could improve response to a common chemotherapy drug, suggests a new study which used cancer cells grown in the lab. Sat, 03 Sep 2011 10:16:16 EDT http://www.sciencedaily.com/releases/2011/09/110903101656.htm http://www.sciencedaily.com/releases/2011/08/110825172459.htm Canadian researchers have discovered that a tumor cell marker is a receptor for measles virus, suggesting the possible use of measles virus to help fight cancer. Thu, 25 Aug 2011 17:24:24 EDT http://www.sciencedaily.com/releases/2011/08/110825172459.htm http://www.sciencedaily.com/releases/2011/08/110825090239.htm Tropical plants may contain the basis of new and effective treatments for ovarian cancer, according to new research. Thu, 25 Aug 2011 09:02:02 EDT http://www.sciencedaily.com/releases/2011/08/110825090239.htm http://www.sciencedaily.com/releases/2011/08/110816133059.htm Using a new approach to developing biomarkers for the very early detection of ovarian cancer, researchers have identified a molecule in the bloodstream of infertile women that could one day be used to screen for those at high risk for the disease -- or even those with early-stage ovarian cancer. Tue, 16 Aug 2011 13:30:30 EDT http://www.sciencedaily.com/releases/2011/08/110816133059.htm http://www.sciencedaily.com/releases/2011/08/110808115412.htm Medical researchers have shown for the first time that engineered human T cells can eradicate deadly human ovarian cancer in immune-deficient mice. Mon, 08 Aug 2011 11:54:54 EDT http://www.sciencedaily.com/releases/2011/08/110808115412.htm http://www.sciencedaily.com/releases/2011/08/110801121906.htm Italian and German scientists have designed peptides to target the protein-protein interface of a key enzyme in DNA synthesis crucial for cancer growth. The peptides act by a novel inhibitory mechanism and curb cancer cell growth in drug resistant ovarian cancer cells. Mon, 01 Aug 2011 12:19:19 EDT http://www.sciencedaily.com/releases/2011/08/110801121906.htm http://www.sciencedaily.com/releases/2011/07/110725091705.htm A new analysis has found that many doctors report that they do not appropriately offer breast and ovarian cancer counseling and testing services to their female patients. The study indicates that efforts are needed to encourage these services for high-risk women and discourage them for average-risk women. Mon, 25 Jul 2011 09:17:17 EDT http://www.sciencedaily.com/releases/2011/07/110725091705.htm http://www.sciencedaily.com/releases/2011/07/110719161542.htm Temporarily suppressing ovarian function with use of the hormone analogue triptorelin reduced the occurrence of early menopause induced by chemotherapy among women with breast cancer, according to a new study. Tue, 19 Jul 2011 16:15:15 EDT http://www.sciencedaily.com/releases/2011/07/110719161542.htm http://www.sciencedaily.com/releases/2011/07/110718151554.htm Some of the most aggressive forms of breast cancer are more vulnerable to chemotherapy when it is combined with a new class of anti-cancer agent, researchers have shown. Mon, 18 Jul 2011 15:15:15 EDT http://www.sciencedaily.com/releases/2011/07/110718151554.htm http://www.sciencedaily.com/releases/2011/07/110718132128.htm Researchers have found that a type of normal stem cell fuels ovarian cancer by encouraging cancer stem cells to grow. Mon, 18 Jul 2011 13:21:21 EDT http://www.sciencedaily.com/releases/2011/07/110718132128.htm http://www.sciencedaily.com/releases/2011/07/110712143012.htm Researchers have discovered that a low dose of the opioid antagonist naltrexone (LDN) markedly suppresses progression of human ovarian cancer transplanted into mice. LDN's antitumor action was comparable to that of chemotherapy (cisplatin, taxol). LDN combined with cisplatin but not taxol had an additive inhibitory action on tumorigenesis. LDN offers a non-toxic and efficacious biologic pathway-related treatment that may benefit patients with this deadly cancer. Tue, 12 Jul 2011 14:30:30 EDT http://www.sciencedaily.com/releases/2011/07/110712143012.htm http://www.sciencedaily.com/releases/2011/07/110705183855.htm Using ovarian surface epithelial cells from mice, researchers have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency. Tue, 05 Jul 2011 18:38:38 EDT http://www.sciencedaily.com/releases/2011/07/110705183855.htm http://www.sciencedaily.com/releases/2011/06/110630131834.htm As part of the Cancer Genome Atlas project, North Carolina researchers have contributed to the most comprehensive an integrated view of cancer genes for any cancer type produced to date. Thu, 30 Jun 2011 13:18:18 EDT http://www.sciencedaily.com/releases/2011/06/110630131834.htm http://www.sciencedaily.com/releases/2011/06/110614131946.htm Ovarian cancer cells use mechanical force to move through tissue and colonize additional organs. A new study contributes to a body of work that will inform future treatments. Eventually, it might be possible to prevent or reverse the spread of ovarian cancer to distant sites in the body. Tue, 14 Jun 2011 13:19:19 EDT http://www.sciencedaily.com/releases/2011/06/110614131946.htm http://www.sciencedaily.com/releases/2011/06/110614131944.htm Scientists have created a laboratory model using time-lapse video microscopic technology that allows observation of early stages of ovarian cancer metastasis. Tue, 14 Jun 2011 13:19:19 EDT http://www.sciencedaily.com/releases/2011/06/110614131944.htm http://www.sciencedaily.com/releases/2011/06/110606131721.htm A new study may provide a novel tool for detection of malignant-stage ovarian cancer. Researchers found that positron emission tomography and computed tomography (PET/CT), which images both functional and anatomical changes in the body, was useful for preoperative cancer imaging of ovarian masses when used with a radiotracer that is actively metabolized by cells as fuel. Physicians imaging patients suspected of having malignant tumors can see where cancerous cells are hyper-metabolizing the tracer and accurately predict whether a mass is malignant, cancerous but stable, or benign. Mon, 06 Jun 2011 13:17:17 EDT http://www.sciencedaily.com/releases/2011/06/110606131721.htm http://www.sciencedaily.com/releases/2011/06/110606092518.htm A test that shows how many eggs a woman has in her ovaries may help young women with breast cancer know what their reproductive function will be after chemotherapy, a new study finds. Mon, 06 Jun 2011 09:25:25 EDT http://www.sciencedaily.com/releases/2011/06/110606092518.htm http://www.sciencedaily.com/releases/2011/06/110604181901.htm Among various genetic mutations for individuals with Lynch syndrome, a hereditary cancer syndrome that carries a high risk of colon cancer and an above-normal risk of other cancers, researchers have identified mutations associated with a lower cancer risk and mutations associated with an increased risk for ovarian and endometrial cancer, according to a new study. Sat, 04 Jun 2011 18:19:19 EDT http://www.sciencedaily.com/releases/2011/06/110604181901.htm http://www.sciencedaily.com/releases/2011/06/110604181856.htm In a clinical trial that included nearly 80,000 women, those who received ovarian cancer screening did not have a reduced risk of death from ovarian cancer compared to women who received usual care, but did have an increase in invasive medical procedures and associated harms as a result of being screened, according to a new study. Sat, 04 Jun 2011 18:18:18 EDT http://www.sciencedaily.com/releases/2011/06/110604181856.htm http://www.sciencedaily.com/releases/2011/06/110601152101.htm Women with the BRCA1 or BRCA2 gene mutations, which are linked to a very high risk of breast and ovarian cancer, can safely take hormone-replacement therapy to mitigate menopausal symptoms after surgical removal of their ovaries, according to new research. Wed, 01 Jun 2011 15:21:21 EDT http://www.sciencedaily.com/releases/2011/06/110601152101.htm http://www.sciencedaily.com/releases/2011/05/110531102251.htm Women with ovarian cancer could be helped by a new test that identifies the specific type of tumor they have. Tue, 31 May 2011 10:22:22 EDT http://www.sciencedaily.com/releases/2011/05/110531102251.htm http://www.sciencedaily.com/releases/2011/05/110527080332.htm Five to 10 percent of all breast cancers are monogenic in origin. In other words, there is a mutation of the genes BRCA1, BRCA2 or other high-risk genes. Researchers report on new insights into the pathogenesis and treatment of hereditary breast and ovarian cancer and newly-discovered risk genes. Fri, 27 May 2011 08:03:03 EDT http://www.sciencedaily.com/releases/2011/05/110527080332.htm http://www.sciencedaily.com/releases/2011/05/110519122244.htm A primary reason that head and neck cancer treatments fail is the tumor cells become resistant to chemotherapy drugs. Now, researchers have found that a compound derived from the Indian spice curcumin can help cells overcome that resistance. Thu, 19 May 2011 12:22:22 EDT http://www.sciencedaily.com/releases/2011/05/110519122244.htm http://www.sciencedaily.com/releases/2011/04/110426091130.htm A motor regulatory protein can block human ovarian tumor growth, leading to eventual cancer cell death and possible new therapies to treat the disease, according to researchers. Tue, 26 Apr 2011 09:11:11 EDT http://www.sciencedaily.com/releases/2011/04/110426091130.htm http://www.sciencedaily.com/releases/2011/04/110425135512.htm A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study finds. Mon, 25 Apr 2011 13:55:55 EDT http://www.sciencedaily.com/releases/2011/04/110425135512.htm http://www.sciencedaily.com/releases/2011/04/110418152324.htm High-grade serous ovarian cancer is thought by many scientists to often be a fallopian tube malignancy masquerading as an ovarian one. While most of the evidence linking the cancer to the fallopian tubes has so far been only circumstantial, a new study suggests there is a direct connection, a finding that could aid in the development of better treatments. Mon, 18 Apr 2011 15:23:23 EDT http://www.sciencedaily.com/releases/2011/04/110418152324.htm http://www.sciencedaily.com/releases/2011/04/110415104548.htm An experimental drug that blocks two points of a crucial cancer cell signaling pathway inhibits the growth of ovarian cancer cells and significantly increases survival in an ovarian cancer mouse model, a study has found. Fri, 15 Apr 2011 10:45:45 EDT http://www.sciencedaily.com/releases/2011/04/110415104548.htm http://www.sciencedaily.com/releases/2011/04/110407132612.htm New research suggests that a layer of cells, which serve as the "breeding ground" for ovarian cancer, may be removed yet allow the women to have children. This would be a vast improvement over the current prevention strategy for women at high risk for ovarian cancer: Removal of the ovaries entirely. Thu, 07 Apr 2011 13:26:26 EDT http://www.sciencedaily.com/releases/2011/04/110407132612.htm http://www.sciencedaily.com/releases/2011/04/110404111040.htm Women with ovarian cancer who have the BRCA2 gene mutation are more likely to survive the malignancy than women with the BRCA1 mutation, or women without either mutation, according to new research. Mon, 04 Apr 2011 11:10:10 EDT http://www.sciencedaily.com/releases/2011/04/110404111040.htm http://www.sciencedaily.com/releases/2011/03/110316142630.htm Measuring the mechanical strength of cancer cell mucus layers provides clues about better ways to treat cancer, and also suggests why some cancer cells are more resistant to drugs than others, according to new research. Healthy tissues naturally secrete mucus to protect against infection. Cancer cells, however, produce far more mucus than healthy cells. Wed, 16 Mar 2011 14:26:26 EDT http://www.sciencedaily.com/releases/2011/03/110316142630.htm http://www.sciencedaily.com/releases/2011/03/110302121832.htm Researchers have zeroed in on a genetic process that may allow ovarian cancer to resist chemotherapy. Wed, 02 Mar 2011 12:18:18 EST http://www.sciencedaily.com/releases/2011/03/110302121832.htm http://www.sciencedaily.com/releases/2011/02/110224121936.htm Family doctors can take more than a month to record ovarian cancer, once diagnosed by a specialist, in one in 10 cases examined in the U.K. Thu, 24 Feb 2011 12:19:19 EST http://www.sciencedaily.com/releases/2011/02/110224121936.htm http://www.sciencedaily.com/releases/2011/02/110203113802.htm Cancer researchers have discovered that a type of regulatory RNA may be effective in fighting ovarian cancer. This new discovery may allow physicians to turn back the clock of the tumor's life cycle to a phase where traditional chemotherapy can better do its job. Thu, 03 Feb 2011 11:38:38 EST http://www.sciencedaily.com/releases/2011/02/110203113802.htm http://www.sciencedaily.com/releases/2011/01/110131133131.htm Scientists have synthesized for the first time a chemical compound called lomaiviticin aglycon, leading to the development of a new class of molecules that appear to target and destroy cancer stem cells. Mon, 31 Jan 2011 13:31:31 EST http://www.sciencedaily.com/releases/2011/01/110131133131.htm http://www.sciencedaily.com/releases/2011/01/110127090624.htm A new study could provide the foundation for a new ovarian cancer treatment option -- one that would use an outside-the-body filtration device to remove a large portion of the free-floating cancer cells that often create secondary tumors. Thu, 27 Jan 2011 09:06:06 EST http://www.sciencedaily.com/releases/2011/01/110127090624.htm http://www.sciencedaily.com/releases/2010/12/101220121103.htm Researchers have been able to confirm in tests that ovarian cancer tissue and healthy tissue smell different. Mon, 20 Dec 2010 12:11:11 EST http://www.sciencedaily.com/releases/2010/12/101220121103.htm