https://www.sciencedaily.com/news/health_medicine/psoriasis/ Psoriasis research. Learn about psoriasis medication as well as the effect of smoking, diet and genetics on psoriasis symptoms. Read about new treatment strategies for skin disorders. en-us Wed, 22 Apr 2026 09:22:15 EDT Wed, 22 Apr 2026 09:22:15 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/health_medicine/psoriasis/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/02/260225081142.htm A gel-like sugar coating on immune cells has been found to play a starring role in psoriasis. Researchers discovered that immune cells shed this outer layer to help them exit the bloodstream and enter inflamed skin. This challenges the long-held idea that only blood vessel walls changed during this process. The finding could help guide new therapies aimed at controlling harmful inflammation. Wed, 25 Feb 2026 08:11:42 EST https://www.sciencedaily.com/releases/2026/02/260225081142.htm https://www.sciencedaily.com/releases/2025/09/250914205829.htm Dry eyes are far more common than previously believed, with over half of adults in the US and Europe experiencing symptoms, yet most remain undiagnosed for years. The large-scale NESTS study reveals that sufferers often endure daily discomfort that disrupts work, driving, and even surgery outcomes. Many accept the condition as part of aging, unaware that simple treatments could provide relief. Mon, 15 Sep 2025 01:05:42 EDT https://www.sciencedaily.com/releases/2025/09/250914205829.htm https://www.sciencedaily.com/releases/2025/05/250527124637.htm Researchers have found that central body fat, especially around the abdomen, is more strongly linked to psoriasis risk than total body fat, particularly in women. This link between central fat and psoriasis remained consistent regardless of genetic predisposition, indicating that abdominal fat is an independent risk factor. The study provides insights that could help improve early risk prediction and guide personalized prevention strategies. Tue, 27 May 2025 12:46:37 EDT https://www.sciencedaily.com/releases/2025/05/250527124637.htm https://www.sciencedaily.com/releases/2025/04/250415144012.htm A new study could lead to more widespread use of imaging technique to improve survival and prevent complications. Tue, 15 Apr 2025 14:40:12 EDT https://www.sciencedaily.com/releases/2025/04/250415144012.htm https://www.sciencedaily.com/releases/2025/04/250403122801.htm Scientists have shown that a sequence of just three amino acids may reduce the severity of psoriasis, when applied topically in an emollient cream. Thu, 03 Apr 2025 12:28:01 EDT https://www.sciencedaily.com/releases/2025/04/250403122801.htm https://www.sciencedaily.com/releases/2025/03/250303141858.htm Psoriasis is one of the most common chronic inflammatory skin diseases, affecting around 250,000 people in Austria. While previous treatment approaches have mainly focused on inhibiting pro-inflammatory immune cells, a study shows that it is possible to restore the function of certain anti-inflammatory immune cells in a targeted manner. The results pave the way for the development of a therapy that not only works more precisely but is also associated with fewer side effects. Mon, 03 Mar 2025 14:18:58 EST https://www.sciencedaily.com/releases/2025/03/250303141858.htm https://www.sciencedaily.com/releases/2025/02/250221125549.htm A diet of fruits and vegetables, whole grains, low-fat dairy foods and lean meats, low in salt and sugar, is associated with reduced psoriasis severity, new research finds. Fri, 21 Feb 2025 12:55:49 EST https://www.sciencedaily.com/releases/2025/02/250221125549.htm https://www.sciencedaily.com/releases/2025/02/250203142254.htm Psoriasis is a chronic skin disease that manifests itself mainly with skin symptoms (dryness, itching, scaly skin, abnormal patches and plaques). It affects about 2% of the population and is mediated by an altered immune system response that triggers the proliferation of skin cells. Depending on the severity, there are different therapeutic options (topical medications, phototherapy, systemic drugs, etc.), but some conventional treatments can have harmful effects on patients. Mon, 03 Feb 2025 14:22:54 EST https://www.sciencedaily.com/releases/2025/02/250203142254.htm https://www.sciencedaily.com/releases/2025/01/250131110435.htm In a new study, researchers have determined that a protein called NF-kB c-Rel can intensify the symptoms of psoriasis when activated by signals from the body's immune system. Understanding how 'c-Rel' affects skin inflammation could lead to new treatments. Fri, 31 Jan 2025 11:04:35 EST https://www.sciencedaily.com/releases/2025/01/250131110435.htm https://www.sciencedaily.com/releases/2025/01/250120113812.htm People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for 'leaky gut', according to new research. These changes in the gut could explain why psoriasis sufferers often have gastrointestinal problems and are more prone to developing Crohn's disease. Mon, 20 Jan 2025 11:38:12 EST https://www.sciencedaily.com/releases/2025/01/250120113812.htm https://www.sciencedaily.com/releases/2025/01/250102162511.htm A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research shows that TTP controls the stability of mRNAs for inflammatory molecules, preventing their overproduction. Using TTP-deficient mice, the team found heightened allergic inflammation, suggesting TTP as a promising therapeutic target for treating allergic and inflammatory diseases. Thu, 02 Jan 2025 16:25:11 EST https://www.sciencedaily.com/releases/2025/01/250102162511.htm https://www.sciencedaily.com/releases/2024/11/241114125648.htm Collecting images of suspicious-looking skin growths and sending them off-site for specialists to analyze is as accurate in identifying skin cancers as having a dermatologist examine them in person, a new study shows. Thu, 14 Nov 2024 12:56:48 EST https://www.sciencedaily.com/releases/2024/11/241114125648.htm https://www.sciencedaily.com/releases/2024/11/241113123311.htm Why do some people develop severe flu symptoms? A study points the finger at an unsung portion of the antibodies our immune systems generate to fend off invading pathogens. Wed, 13 Nov 2024 12:33:11 EST https://www.sciencedaily.com/releases/2024/11/241113123311.htm https://www.sciencedaily.com/releases/2024/11/241112123220.htm Researchers have developed a patch for easier and more effective treatment of psoriasis. The method may also be used in treatment of other inflammatory skin diseases. Tue, 12 Nov 2024 12:32:20 EST https://www.sciencedaily.com/releases/2024/11/241112123220.htm https://www.sciencedaily.com/releases/2024/10/241016115854.htm Prenatal human skin atlas and organoid will accelerate research into congenital diseases and lead to clinical applications for regenerative medicine. Wed, 16 Oct 2024 11:58:54 EDT https://www.sciencedaily.com/releases/2024/10/241016115854.htm https://www.sciencedaily.com/releases/2024/09/240926131933.htm Scientists believe the hormone hepcidin, when produced in the skin, may be the root cause of psoriasis -- a chronic and sometimes debilitating skin disease that affects 2-3% of the global population. Thu, 26 Sep 2024 13:19:33 EDT https://www.sciencedaily.com/releases/2024/09/240926131933.htm https://www.sciencedaily.com/releases/2024/09/240904130825.htm The most frequently used mpox vaccine provides partial immunity to the disease but isn't always able to prevent severe symptoms or disease transmission. A new vaccine candidate from Moderna, mRNA-1769, more effectively limits symptoms and disease duration in primates that were infected with a lethal strain of the mpox virus when compared to a currently licensed modified vaccinia Ankara (MVA) vaccine. Wed, 04 Sep 2024 13:08:25 EDT https://www.sciencedaily.com/releases/2024/09/240904130825.htm https://www.sciencedaily.com/releases/2024/05/240520155512.htm A certain biological pathway drives the inflammation seen in the skin disease psoriasis. Mon, 20 May 2024 15:55:12 EDT https://www.sciencedaily.com/releases/2024/05/240520155512.htm https://www.sciencedaily.com/releases/2024/03/240327182533.htm Artificial intelligence (AI) may serve as a future tool for neurologists to help locate where in the brain a stroke occurred. In a new study, AI processed text from health histories and neurologic examinations to locate lesions in the brain. The study looked specifically at the large language model called generative pre-trained transformer 4 (GPT-4). Wed, 27 Mar 2024 18:25:33 EDT https://www.sciencedaily.com/releases/2024/03/240327182533.htm https://www.sciencedaily.com/releases/2024/03/240325114127.htm Scientists have discovered a gene mutation is responsible for causing psoriasis -- a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. According to researchers, if two copies of this mutated gene (known as IKBKB) are present, patients with psoriasis may go on to develop psoriatic arthritis, leaving them with joint pain, stiffness and swelling. It's hoped the findings will lead to improved diagnosis and treatment for patients with psoriasis and psoriatic arthritis -- conditions that patients say carry stigma in the community. Mon, 25 Mar 2024 11:41:27 EDT https://www.sciencedaily.com/releases/2024/03/240325114127.htm https://www.sciencedaily.com/releases/2024/03/240320122438.htm A mobile app that uses artificial intelligence, AI, to analyze images of suspected skin lesions can diagnose melanoma with very high precision, according to a new study. Wed, 20 Mar 2024 12:24:38 EDT https://www.sciencedaily.com/releases/2024/03/240320122438.htm https://www.sciencedaily.com/releases/2024/03/240320122408.htm Using advanced methodology, scientists have been able to reveal at the cellular level how lesions in multiple sclerosis develop. Wed, 20 Mar 2024 12:24:08 EDT https://www.sciencedaily.com/releases/2024/03/240320122408.htm https://www.sciencedaily.com/releases/2024/02/240222122339.htm A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold. Thu, 22 Feb 2024 12:23:39 EST https://www.sciencedaily.com/releases/2024/02/240222122339.htm https://www.sciencedaily.com/releases/2024/01/240124191459.htm New research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood intervention. Wed, 24 Jan 2024 19:14:59 EST https://www.sciencedaily.com/releases/2024/01/240124191459.htm https://www.sciencedaily.com/releases/2024/01/240103154231.htm Traumatic brain injuries (TBIs) can cause lasting damage, but stopping the rampant brain inflammation they cause is difficult. A team at the Wyss, @SEAS and @MGH led by Samir Mitragotri has made a new treatment using macrophages -- immune cells that migrate to the brain. By attaching microparticle 'backpacks' that kept the macrophages in a healing state, they reduced the size of brain lesions by 56% in pigs with a mock TBI. Wed, 03 Jan 2024 15:42:31 EST https://www.sciencedaily.com/releases/2024/01/240103154231.htm https://www.sciencedaily.com/releases/2023/11/231130184245.htm For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt. Thu, 30 Nov 2023 18:42:45 EST https://www.sciencedaily.com/releases/2023/11/231130184245.htm https://www.sciencedaily.com/releases/2023/10/231026131431.htm Genetic analysis of psoriasis shows somatic mutations are not linked to the development or the spread of the condition. Thu, 26 Oct 2023 13:14:31 EDT https://www.sciencedaily.com/releases/2023/10/231026131431.htm https://www.sciencedaily.com/releases/2023/05/230525141313.htm Patients with MS show structural abnormalities in their white matter even before MS inflammation develops. Could this finding lead to a target for a new treatment to prevent MS inflammation? Thu, 25 May 2023 14:13:13 EDT https://www.sciencedaily.com/releases/2023/05/230525141313.htm https://www.sciencedaily.com/releases/2023/04/230421122637.htm Multiple sclerosis (MS) is an autoimmune disease that destroys the protective myelin covering around nerves. Every five minutes, someone is diagnosed with the disease around the world, adding to about 2.8 million individuals that currently have to live with it. Now researchers have developed a cell therapy that leverages myeloid cells, the very type of immune cells that cause MS-triggering nerve inflammation in patients. By attaching 'backpacks' loaded with anti-inflammatory drugs to the cells, and infusing them into a mouse model of MS, they were able to partially reverse paralysis and restore movement. Fri, 21 Apr 2023 12:26:37 EDT https://www.sciencedaily.com/releases/2023/04/230421122637.htm https://www.sciencedaily.com/releases/2023/01/230104085301.htm A common fatty acid found in the Western diet breaks down into compounds that contribute to increased temperature and pain -- but not itch -- sensitivity in psoriatic lesions. Wed, 04 Jan 2023 08:53:01 EST https://www.sciencedaily.com/releases/2023/01/230104085301.htm https://www.sciencedaily.com/releases/2022/11/221129134412.htm New research yields a novel method to use ultrasound to enhance machine learning's ability to accurately diagnose -- or rule out -- ovarian cancer. Tue, 29 Nov 2022 13:44:12 EST https://www.sciencedaily.com/releases/2022/11/221129134412.htm https://www.sciencedaily.com/releases/2022/09/220923153043.htm Two recent studies reveal how skin forms differently across different areas of the body from the face and underarms to the palms of our hands and feet. By profiling the changes in skin, researchers found that the differences have a direct impact for how various skin diseases form across the body. Fri, 23 Sep 2022 15:30:43 EDT https://www.sciencedaily.com/releases/2022/09/220923153043.htm https://www.sciencedaily.com/releases/2022/08/220829112839.htm An international consortium of researchers has identified genetic variants in 10 genes that elevate a person's susceptibility to Crohn's disease, a form of inflammatory bowel disease. The findings highlight the causal role of mesenchymal cells in intestinal inflammation, helping to zero in on the genetic roots of inflammatory bowel disease. Mon, 29 Aug 2022 11:28:39 EDT https://www.sciencedaily.com/releases/2022/08/220829112839.htm https://www.sciencedaily.com/releases/2022/08/220826131220.htm Researchers have published one of the earliest studies assessing the use of tecovirimat to treat monkeypox symptoms and skin lesions. The antiviral drug approved for smallpox treatment appeared to be safe and effective in 25 patients with monkeypox (MPX). Fri, 26 Aug 2022 13:12:20 EDT https://www.sciencedaily.com/releases/2022/08/220826131220.htm https://www.sciencedaily.com/releases/2022/07/220714165814.htm Researchers have shown that treating precancerous anal growths called high-grade squamous intraepithelial lesions (HSILs) in persons living with HIV significantly decreased the progression to anal cancer. Thu, 14 Jul 2022 16:58:14 EDT https://www.sciencedaily.com/releases/2022/07/220714165814.htm https://www.sciencedaily.com/releases/2022/07/220713114639.htm The treatment of inflammatory bowel disease (IBD)-associated dysplasia is often challenging due to diagnostic techniques that are unable to accurately differentiate and classify the severity of neoplastic lesions. Now, researchers have developed an AI-system based on a conventional neural network, by training it with endoscopic images of neoplastic lesions. This system displayed a higher diagnostic ability in the classification of the lesions, as compared to that of endoscopists. Wed, 13 Jul 2022 11:46:39 EDT https://www.sciencedaily.com/releases/2022/07/220713114639.htm https://www.sciencedaily.com/releases/2022/07/220706133304.htm About one third of those who suffer from psoriasis develop inflammation in their joints (psoriatic arthritis) as a result of the chronic skin condition. A research team has now discovered a key starting point for inhibiting inflammation in both psoriasis and psoriatic arthritis. The researchers' findings may form the basis for developing new treatment, diagnostic and prevention strategies. Wed, 06 Jul 2022 13:33:04 EDT https://www.sciencedaily.com/releases/2022/07/220706133304.htm https://www.sciencedaily.com/releases/2022/06/220601170205.htm A study suggests that substances touted to improve athletic performance can activate a receptor that accelerates the progression of pre-cancerous lesions to pancreatic cancer in mice. Wed, 01 Jun 2022 17:02:05 EDT https://www.sciencedaily.com/releases/2022/06/220601170205.htm https://www.sciencedaily.com/releases/2022/05/220512092631.htm Researchers have identified a new enzyme involved in controlling cell death, in findings that could lead to better treatment options for a range of inflammatory conditions, cancers and viruses. Thu, 12 May 2022 09:26:31 EDT https://www.sciencedaily.com/releases/2022/05/220512092631.htm https://www.sciencedaily.com/releases/2022/04/220418143840.htm Scientists have developed a new nanotechnology approach for locating and removing the painful and dangerous lesions associated with endometriosis, a common gynecological condition in women of childbearing age. Mon, 18 Apr 2022 14:38:40 EDT https://www.sciencedaily.com/releases/2022/04/220418143840.htm https://www.sciencedaily.com/releases/2022/03/220322122822.htm The appearance of ovarian lesions on ultrasound is an effective predictor of cancer risk that can help women avoid unnecessary surgery, according to a new study. Tue, 22 Mar 2022 12:28:22 EDT https://www.sciencedaily.com/releases/2022/03/220322122822.htm https://www.sciencedaily.com/releases/2021/12/211217172730.htm As our brains age, small lesions begin to pop up in the bundles of white matter that carry messages between our neurons. The lesions can damage this white matter and lead to cognitive deficits. Now, researchers not only provide an explanation for the location of these lesions but also how they develop in the first place. Fri, 17 Dec 2021 17:27:30 EST https://www.sciencedaily.com/releases/2021/12/211217172730.htm https://www.sciencedaily.com/releases/2021/12/211217102842.htm A proof-of-concept trial has identified a drug that may offer benefit some patients hospitalized with COVID-19 pneumonia. Fri, 17 Dec 2021 10:28:42 EST https://www.sciencedaily.com/releases/2021/12/211217102842.htm https://www.sciencedaily.com/releases/2021/11/211119155451.htm About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies -- and for many, the relief is temporary. Scientists have discovered how a key protein called TWEAK damages skin cells in psoriasis patients. Their findings, in mice and with human skin cells, suggest targeting TWEAK may help control the disease. Fri, 19 Nov 2021 15:54:51 EST https://www.sciencedaily.com/releases/2021/11/211119155451.htm https://www.sciencedaily.com/releases/2021/10/211027122125.htm Researchers look at the use of intravenous immunoglobulin for treatment of Kawasaki disease and multisystem inflammatory syndrome in children, a rare reaction to SARS-CoV-2. Wed, 27 Oct 2021 12:21:25 EDT https://www.sciencedaily.com/releases/2021/10/211027122125.htm https://www.sciencedaily.com/releases/2021/10/211026124318.htm An international team of scientists has identified a new connection between certain molecules produced by the microbiome and the function of a protein that impacts gut inflammation. Tue, 26 Oct 2021 12:43:18 EDT https://www.sciencedaily.com/releases/2021/10/211026124318.htm https://www.sciencedaily.com/releases/2021/10/211022171455.htm Interleukin-12 -- a messenger molecule of immune cells -- was long considered to trigger the development of psoriasis. Now, researchers have shown that interleukin-12 does not actually cause the skin disease but protects against it. This also explains why common psoriasis drugs that block the messenger show insufficient treatment efficacy. Fri, 22 Oct 2021 17:14:55 EDT https://www.sciencedaily.com/releases/2021/10/211022171455.htm https://www.sciencedaily.com/releases/2021/10/211004104229.htm Patients with psoriasis have reported that glycerin, an inexpensive, harmless, slightly sweet liquid high on the list of ingredients in many skin lotions, is effective at combating their psoriasis and now scientists have objective evidence to support their reports. Mon, 04 Oct 2021 10:42:29 EDT https://www.sciencedaily.com/releases/2021/10/211004104229.htm https://www.sciencedaily.com/releases/2021/08/210812092737.htm Results from a new study reveal that targeting interferon kappa, a protein made by skin cells, may reduce the severity of psoriasis.  Researchers say the findings will bring physicians one step closer to optimizing treatments for patients with the autoimmune disease. Thu, 12 Aug 2021 09:27:37 EDT https://www.sciencedaily.com/releases/2021/08/210812092737.htm https://www.sciencedaily.com/releases/2021/08/210803175229.htm Identification of protein signatures of remodeled airways may help develop therapies to improve long-term outcomes, according to new research. Tue, 03 Aug 2021 17:52:29 EDT https://www.sciencedaily.com/releases/2021/08/210803175229.htm https://www.sciencedaily.com/releases/2021/06/210622161046.htm Diet rich in sugar and fat leads to disruption in the gut's microbial culture and contributes to inflammatory skin diseases such as psoriasis. Research shows that switching to a more balanced diet restores the gut's health and suppresses inflammation. Tue, 22 Jun 2021 16:10:46 EDT https://www.sciencedaily.com/releases/2021/06/210622161046.htm https://www.sciencedaily.com/releases/2021/05/210521115349.htm Chronic skin itch affects 7% of U.S. adults but until recently neuroscientists considered the mechanisms of skin itch the same. Researchers have uncovered differences in itch on hairy versus non-hairy skin that could lead to more effective treatments for patients with persistent skin itching. Fri, 21 May 2021 11:53:49 EDT https://www.sciencedaily.com/releases/2021/05/210521115349.htm https://www.sciencedaily.com/releases/2021/05/210518114214.htm In sports, it is common practice to apply ice to sore muscles in order to reduce inflammation. However, a new study on mice has revealed that icing severe muscle injuries may actually prolong the healing process. The results indicate that cooling the injury makes it difficult for macrophages to enter the damaged cells in order to repair them. Tue, 18 May 2021 11:42:14 EDT https://www.sciencedaily.com/releases/2021/05/210518114214.htm https://www.sciencedaily.com/releases/2021/04/210426140754.htm People who take a commonly-prescribed drug for inflammatory bowel disease (IBD) should not assume they are protected after a first dose of COVID-19 vaccine, after a large-scale study found many had poor antibody responses. Mon, 26 Apr 2021 14:07:54 EDT https://www.sciencedaily.com/releases/2021/04/210426140754.htm https://www.sciencedaily.com/releases/2021/04/210414202446.htm Biomedical engineers have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system. In mouse models of psoriasis, the team showed that their nanofiber-based drug could effectively mitigate damaging inflammation as effectively as a gold-standard therapy. Wed, 14 Apr 2021 20:24:46 EDT https://www.sciencedaily.com/releases/2021/04/210414202446.htm https://www.sciencedaily.com/releases/2021/03/210322195835.htm Infliximab, a powerful biologic that is used to treat inflammatory bowel disease (IBD), blunts the body's immune response to COVID-19 infection, new research indicates. Mon, 22 Mar 2021 19:58:35 EDT https://www.sciencedaily.com/releases/2021/03/210322195835.htm https://www.sciencedaily.com/releases/2021/02/210217151108.htm A deep learning-based system enables dermatologist-level identification of suspicious skin lesions from smartphone photos, allowing better screening. Wed, 17 Feb 2021 15:11:08 EST https://www.sciencedaily.com/releases/2021/02/210217151108.htm https://www.sciencedaily.com/releases/2021/01/210126105903.htm A study indicates that the gut microbiota of patients suffering from inflammatory gastrointestinal disorders can be used to predict whether they will benefit from expensive therapies. The study also confirms the key role of therapies that have a beneficial effect on the gut microbiota in inflammatory bowel diseases. Tue, 26 Jan 2021 10:59:03 EST https://www.sciencedaily.com/releases/2021/01/210126105903.htm https://www.sciencedaily.com/releases/2021/01/210121163142.htm Scientists have created a highly detailed map of skin, which reveals that cellular processes from development are re-activated in cells from patients with eczema and psoriasis inflammatory skin diseases. The study offers potential new drug targets for treating these painful skin diseases and provides a new understanding of inflammatory disease. The research could also provide a template for regenerating healthy skin in the laboratory. Thu, 21 Jan 2021 16:31:42 EST https://www.sciencedaily.com/releases/2021/01/210121163142.htm https://www.sciencedaily.com/releases/2021/01/210112110116.htm Scientists have now demonstrated a connection between inferior physical fitness in young adults and elevated risk of the autoimmune disease psoriasis. For the male recruits to compulsory military training who were rated as the least fit, the risk of developing psoriasis later was 35 percent higher than for the fittest. Tue, 12 Jan 2021 11:01:16 EST https://www.sciencedaily.com/releases/2021/01/210112110116.htm