https://www.sciencedaily.com/news/health_medicine/ulcers/ Read the latest medical research on ulcers - causes and treatments. Read about the role of bacteria in the gut. en-us Tue, 21 Apr 2026 00:09:54 EDT Tue, 21 Apr 2026 00:09:54 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/health_medicine/ulcers/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/04/260417224527.htm Extra virgin olive oil might help protect your brain by working through your gut. A two-year study found that people who consumed it had better cognitive performance and more diverse gut bacteria than those using refined olive oil. Researchers even identified specific microbes linked to these benefits. The findings suggest that choosing high-quality olive oil could be a simple way to support brain health as you age. Sat, 18 Apr 2026 23:45:14 EDT https://www.sciencedaily.com/releases/2026/04/260417224527.htm https://www.sciencedaily.com/releases/2026/04/260413043131.htm Spending time with close companions might do more than strengthen bonds—it could also reshape your gut bacteria. In a study of island birds, those with stronger social ties shared more gut microbes, especially types that require direct contact to spread. This suggests that social interaction itself—not just shared space—drives microbial exchange. The same process may be happening in human households through everyday closeness. Mon, 13 Apr 2026 23:40:13 EDT https://www.sciencedaily.com/releases/2026/04/260413043131.htm https://www.sciencedaily.com/releases/2026/04/260408225944.htm A new study reveals that gut bacteria may play a key role in triggering ALS and frontotemporal dementia. Harmful sugars produced by these microbes can spark immune responses that damage the brain. This breakthrough explains why some genetically at-risk people develop the diseases while others don’t. Even more promising, reducing these sugars improved brain health in experiments, hinting at new treatment possibilities. Thu, 09 Apr 2026 06:36:40 EDT https://www.sciencedaily.com/releases/2026/04/260408225944.htm https://www.sciencedaily.com/releases/2026/04/260406192907.htm A surprising new study reveals that what you eat could play a powerful role in fighting cholera, a deadly diarrheal disease. Researchers found that diets rich in certain proteins—especially casein from dairy and wheat gluten—can dramatically reduce the ability of cholera bacteria to take hold in the gut, in some cases cutting infection levels by up to 100 times. These proteins appear to disable a key “weapon” the bacteria use to attack other microbes and dominate the gut environment. Tue, 07 Apr 2026 03:22:01 EDT https://www.sciencedaily.com/releases/2026/04/260406192907.htm https://www.sciencedaily.com/releases/2026/03/260328024519.htm Scientists have uncovered how your body actually tells your brain to stop eating when you’re sick. In a new study, researchers found that specialized cells in the gut detect parasites and send signals that ultimately trigger the brain to suppress appetite. This process builds over time, explaining why you may feel fine at first but then suddenly lose interest in food as an infection takes hold. Sat, 28 Mar 2026 04:35:02 EDT https://www.sciencedaily.com/releases/2026/03/260328024519.htm https://www.sciencedaily.com/releases/2026/03/260326080752.htm Gut bacteria aren’t just passive passengers—they can actively send proteins straight into our cells. Using microscopic injection systems, even harmless microbes can influence immune responses and metabolic pathways. Researchers found these interactions may play a role in inflammatory diseases like Crohn’s. It’s a major shift in how scientists understand the microbiome’s power over human health. Fri, 27 Mar 2026 08:23:14 EDT https://www.sciencedaily.com/releases/2026/03/260326080752.htm https://www.sciencedaily.com/releases/2026/03/260317064444.htm Early life stress may set the stage for long-term digestive problems by disrupting the gut-brain connection. Studies in both mice and thousands of children found links to symptoms like pain, constipation, and IBS. Scientists discovered that different biological pathways control different gut issues, hinting at more personalized treatments in the future. The research also highlights how a child’s early environment can have lasting physical effects—not just emotional ones. Tue, 17 Mar 2026 22:08:54 EDT https://www.sciencedaily.com/releases/2026/03/260317064444.htm https://www.sciencedaily.com/releases/2026/03/260314030516.htm Researchers have created “Smart Underwear,” a wearable device that measures flatulence by detecting hydrogen produced by gut microbes. Early tests suggest people may pass gas about 32 times a day—much higher than previous estimates. The device gives scientists a new way to track gut microbial activity in everyday life. It will power a new nationwide study called the Human Flatus Atlas to map normal patterns of gas production. Sat, 14 Mar 2026 18:36:43 EDT https://www.sciencedaily.com/releases/2026/03/260314030516.htm https://www.sciencedaily.com/releases/2026/03/260313002640.htm Researchers have identified two gut bacteria that can produce serotonin, a key chemical that regulates bowel movements. In experiments with mice lacking serotonin, the microbes boosted serotonin levels, increased nerve cells in the colon, and normalized intestinal movement. The study also found that people with IBS have lower levels of one of these bacteria. The discovery suggests gut microbes could become a powerful new target for treating digestive disorders. Fri, 13 Mar 2026 23:28:29 EDT https://www.sciencedaily.com/releases/2026/03/260313002640.htm https://www.sciencedaily.com/releases/2026/02/260225081217.htm Eating nothing but oatmeal for just two days might sound extreme, but it delivered a striking payoff in a new clinical trial. People with metabolic syndrome who followed a short, calorie-reduced oat-based plan saw their harmful LDL cholesterol drop by 10%, along with modest weight loss and lower blood pressure. Even more surprising, the cholesterol benefits were still visible six weeks later. Wed, 25 Feb 2026 11:37:57 EST https://www.sciencedaily.com/releases/2026/02/260225081217.htm https://www.sciencedaily.com/releases/2026/02/260225081159.htm Popular acid reflux drugs such as Prilosec, Nexium, and Protonix may carry hidden risks when taken long term. A new study found that extended use disrupted iron and calcium levels in rats, changes associated with anemia and osteoporosis risk. Researchers also observed shifts in mineral balance across multiple organs. Experts say the medications are effective, but prolonged use without medical guidance could have unintended consequences. Thu, 26 Feb 2026 07:27:39 EST https://www.sciencedaily.com/releases/2026/02/260225081159.htm https://www.sciencedaily.com/releases/2026/02/260222092317.htm Training harder may do more than build muscle—it could transform your gut. Researchers found that intense workouts change the balance of bacteria and important compounds in athletes’ digestive systems. When training loads dropped, diet quality slipped and digestion slowed, triggering different microbial shifts. These hidden changes might influence performance in ways scientists are only beginning to understand. Mon, 23 Feb 2026 23:45:43 EST https://www.sciencedaily.com/releases/2026/02/260222092317.htm https://www.sciencedaily.com/releases/2026/02/260219040745.htm A newly discovered bacterial duo may be the hidden cause of chronic constipation. The two microbes break down the colon’s protective mucus layer, leaving stool dry and hard — a problem traditional laxatives don’t fix. Parkinson’s patients, who often struggle with constipation years before tremors appear, have higher levels of these bacteria. Blocking the bacteria’s mucus-destroying enzyme prevented constipation in mice, hinting at a new treatment strategy. Thu, 19 Feb 2026 08:46:05 EST https://www.sciencedaily.com/releases/2026/02/260219040745.htm https://www.sciencedaily.com/releases/2026/02/260211204210.htm A global study has uncovered a mysterious group of gut bacteria that shows up again and again in healthy people. Known as CAG-170, these microbes were found at lower levels in people with a range of chronic diseases. Genetic clues suggest they help digest food and support the broader gut ecosystem. Researchers say the discovery could reshape how we measure and maintain gut health. Sat, 14 Feb 2026 07:58:31 EST https://www.sciencedaily.com/releases/2026/02/260211204210.htm https://www.sciencedaily.com/releases/2026/02/260208011017.htm Your gut is home to trillions of bacteria that constantly “sense” their surroundings to survive and thrive. New research shows that beneficial gut microbes, especially common Clostridia bacteria, can detect a surprisingly wide range of chemical signals produced during digestion, including byproducts of fats, proteins, sugars, and even DNA. These microbes use specialized sensors to move toward valuable nutrients, with lactate and formate standing out as especially important fuel sources. Sun, 08 Feb 2026 15:56:24 EST https://www.sciencedaily.com/releases/2026/02/260208011017.htm https://www.sciencedaily.com/releases/2026/02/260201231240.htm Chronic stress can damage the gut’s protective lining, triggering inflammation that may worsen depression. New research shows that stress lowers levels of a protein called Reelin, which plays a key role in both gut repair and brain health. Remarkably, a single injection restored Reelin levels and produced antidepressant-like effects in preclinical models. The findings hint at a future treatment that targets depression through the gut–brain connection. Mon, 02 Feb 2026 11:37:15 EST https://www.sciencedaily.com/releases/2026/02/260201231240.htm https://www.sciencedaily.com/releases/2026/01/260131085024.htm Researchers found that small doses of an antibiotic can coax gut bacteria into producing a life-extending compound. In worms, this led to longer lifespans, while mice showed healthier cholesterol and insulin changes. Because the drug stays in the gut, it avoids toxic side effects. The study points to a new way of promoting health by targeting microbes rather than the body itself. Sun, 01 Feb 2026 02:49:48 EST https://www.sciencedaily.com/releases/2026/01/260131085024.htm https://www.sciencedaily.com/releases/2026/01/260127112125.htm A sweeping scientific review highlights wild blueberries as a standout food for cardiometabolic health. The strongest evidence shows improvements in blood vessel function, with encouraging signs for blood pressure, cholesterol, blood sugar, gut health, and cognition. Researchers suggest these benefits may kick in within hours—or build over weeks—thanks to the berries’ unique mix of polyphenols and fiber. Tue, 27 Jan 2026 23:32:03 EST https://www.sciencedaily.com/releases/2026/01/260127112125.htm https://www.sciencedaily.com/releases/2026/01/260122074659.htm Scientists studying genetic data from over a quarter million people have uncovered new clues about what controls how fast the gut moves. They identified multiple DNA regions linked to bowel movement frequency, confirming known gut pathways and revealing new ones. The biggest surprise was a strong connection to vitamin B1, a common nutrient not usually linked to digestion. Thu, 22 Jan 2026 07:53:07 EST https://www.sciencedaily.com/releases/2026/01/260122074659.htm https://www.sciencedaily.com/releases/2026/01/260120015650.htm Scientists have uncovered a surprising reason why some chronic wounds refuse to heal, even when treated with antibiotics. A common bacterium found in long-lasting wounds does not just resist drugs. It actively releases damaging molecules that overwhelm skin cells and stop them from repairing tissue. Researchers discovered that neutralizing these harmful molecules with antioxidants allows skin cells to recover and restart healing. Tue, 20 Jan 2026 02:35:17 EST https://www.sciencedaily.com/releases/2026/01/260120015650.htm https://www.sciencedaily.com/releases/2026/01/260120000305.htm A new study suggests that micro-doses of THC could help counter many long-term side effects of HIV treatment without causing intoxication. In animal models, low-dose THC reduced inflammation, improved gut bacteria, boosted serotonin, and lowered harmful cholesterol and bile acids. Surprisingly, it also reduced circulating levels of antiretroviral drugs while maintaining viral suppression, potentially protecting the liver. Scientists say the results point to a promising new approach for managing chronic complications of HIV. Wed, 21 Jan 2026 01:36:19 EST https://www.sciencedaily.com/releases/2026/01/260120000305.htm https://www.sciencedaily.com/releases/2026/01/260106001916.htm A familiar mouth bacterium best known for causing cavities may also be quietly influencing the brain. Scientists found that when this microbe settles in the gut, it produces compounds that can travel through the bloodstream and harm neurons involved in movement. In animal studies, this process triggered inflammation, motor problems, and brain changes linked to Parkinson’s disease. The findings hint that protecting oral and gut health could help protect the brain as well. Tue, 06 Jan 2026 22:25:32 EST https://www.sciencedaily.com/releases/2026/01/260106001916.htm https://www.sciencedaily.com/releases/2026/01/260105165806.htm New research shows gut bacteria can directly influence how the brain develops and functions. When scientists transferred microbes from different primates into mice, the animals’ brains began to resemble those of the original host species. Microbes from large-brained primates boosted brain energy and learning pathways, while others triggered very different patterns. The results suggest gut microbes may have played a hidden role in shaping the human brain—and could influence mental health. Mon, 05 Jan 2026 18:23:28 EST https://www.sciencedaily.com/releases/2026/01/260105165806.htm https://www.sciencedaily.com/releases/2026/01/260104202815.htm A large study has revealed that dozens of widely used chemicals can damage beneficial gut bacteria. Many of these substances, found in pesticides and everyday industrial products, were never thought to affect living organisms at all. When gut bacteria are stressed by these chemicals, some may also become resistant to antibiotics. The research raises new questions about how chemical exposure could be influencing human health behind the scenes. Mon, 05 Jan 2026 05:46:41 EST https://www.sciencedaily.com/releases/2026/01/260104202815.htm https://www.sciencedaily.com/releases/2025/12/251225080732.htm Scientists discovered that common food emulsifiers consumed by mother mice altered their offspring’s gut microbiome from the very first weeks of life. These changes interfered with normal immune system training, leading to long-term inflammation. As adults, the offspring were more vulnerable to gut disorders and obesity. The findings suggest that food additives may have hidden, lasting effects beyond those who consume them directly. Fri, 26 Dec 2025 03:57:30 EST https://www.sciencedaily.com/releases/2025/12/251225080732.htm https://www.sciencedaily.com/releases/2025/12/251223043938.htm Scientists studying thousands of rats discovered that gut bacteria are shaped by both personal genetics and the genetics of social partners. Some genes promote certain microbes that can spread between individuals living together. When researchers accounted for this social sharing, genetic influence on the microbiome turned out to be much stronger than previously thought. The study suggests genes can affect others indirectly, without DNA ever being exchanged. Tue, 23 Dec 2025 23:31:13 EST https://www.sciencedaily.com/releases/2025/12/251223043938.htm https://www.sciencedaily.com/releases/2025/12/251217082459.htm Sorbitol, a popular sugar-free sweetener, may not be as harmless as its label suggests. Researchers found it can be turned into fructose in the liver, triggering effects similar to regular sugar. Gut bacteria can neutralize some of it—but too much sorbitol or glucose can overwhelm that defense. The result: yet another “healthy” sweetener that may stress the liver. Wed, 17 Dec 2025 08:24:59 EST https://www.sciencedaily.com/releases/2025/12/251217082459.htm https://www.sciencedaily.com/releases/2025/12/251202052215.htm Researchers discovered that 168 common chemicals can disrupt the growth of beneficial gut bacteria, with some also promoting antibiotic resistance. Many of these substances—found in food, water, and household items—weren’t previously suspected of affecting living organisms. A new machine learning model now predicts which chemicals may harm the microbiome. The findings suggest safety testing must expand to consider gut health. Tue, 02 Dec 2025 23:44:07 EST https://www.sciencedaily.com/releases/2025/12/251202052215.htm https://www.sciencedaily.com/releases/2025/11/251112011818.htm Scientists in Seoul have uncovered 15 gut bacterial species linked to coronary artery disease, showing that microbes can influence heart health far beyond digestion. Their findings reveal how shifts in gut microbial function — including inflammation, loss of protective species, and overactive metabolic pathways — may drive disease progression. Intriguingly, even “good” bacteria like Faecalibacterium prausnitzii and Akkermansia muciniphila can become harmful under certain conditions. Wed, 12 Nov 2025 09:22:10 EST https://www.sciencedaily.com/releases/2025/11/251112011818.htm https://www.sciencedaily.com/releases/2025/11/251104094136.htm Researchers have, for the first time, estimated how quickly E. coli bacteria can spread between people — and one strain moves as fast as swine flu. Using genomic data from the UK and Norway, scientists modeled bacterial transmission rates and discovered key differences between strains. Their work offers a new way to monitor and control antibiotic-resistant bacteria in both communities and hospitals. Tue, 04 Nov 2025 23:25:35 EST https://www.sciencedaily.com/releases/2025/11/251104094136.htm https://www.sciencedaily.com/releases/2025/09/250919085235.htm For decades, scientists have puzzled over why smoking makes Crohn’s disease worse but seems to protect people from ulcerative colitis. Now, researchers at RIKEN have discovered that smoking creates metabolites like hydroquinone that allow mouth bacteria—especially Streptococcus mitis—to settle in the gut. These bacteria spark an immune response that reduces inflammation in colitis but worsens Crohn’s. The findings open the door to new therapies using probiotics or targeted compounds that mimic smoking’s protective effects without its deadly risks. Fri, 19 Sep 2025 20:28:11 EDT https://www.sciencedaily.com/releases/2025/09/250919085235.htm https://www.sciencedaily.com/releases/2025/09/250907172649.htm Scientists have uncovered a surprising new pathway behind life-threatening food allergies. Instead of histamine, a different chemical called leukotrienes drives severe reactions in the gut. These molecules, released by specialized mast cells, trigger inflammation and anaphylaxis when food allergens are ingested. Drugs already approved for asthma may block this pathway, opening the door to new ways to prevent or treat food-induced allergic emergencies. Mon, 08 Sep 2025 04:48:45 EDT https://www.sciencedaily.com/releases/2025/09/250907172649.htm https://www.sciencedaily.com/releases/2025/08/250830001207.htm Scientists have uncovered a surprising new healing mechanism in injured cells called cathartocytosis, in which cells "vomit" out their internal machinery to revert more quickly to a stem cell-like state. While this messy shortcut helps tissues regenerate faster, it also leaves behind debris that can fuel inflammation and even cancer. Sat, 30 Aug 2025 06:56:04 EDT https://www.sciencedaily.com/releases/2025/08/250830001207.htm https://www.sciencedaily.com/releases/2025/08/250825015635.htm UBC researchers revealed that gut bacteria can digest cellulose-based food thickeners, once thought indigestible, by using enzymes activated by natural dietary fibers. This discovery suggests these common additives may play a more active role in our nutrition than previously believed. Mon, 25 Aug 2025 04:35:05 EDT https://www.sciencedaily.com/releases/2025/08/250825015635.htm https://www.sciencedaily.com/releases/2025/08/250805041623.htm Your gut may be talking to your brain in ways we never imagined. Scientists have discovered a “neurobiotic sense” — a rapid-response system where colon cells detect microbial proteins and instantly send appetite-suppressing messages to the brain. This breakthrough reveals how our gut microbes might shape not just digestion, but behavior, mood, and even mental health. Wed, 06 Aug 2025 01:14:05 EDT https://www.sciencedaily.com/releases/2025/08/250805041623.htm https://www.sciencedaily.com/releases/2025/07/250730030346.htm A new global study reveals a striking post-pandemic surge in gut-brain disorders like IBS and functional dyspepsia. Researchers compared data from 2017 and 2023 and discovered sharp increases IBS up 28% and dyspepsia nearly 44%. Those suffering from long COVID were especially vulnerable, reporting more anxiety, depression, and worse quality of life. These findings spotlight the urgent need for deeper investigation into the gut-brain axis and revised care models in a post-COVID world. Wed, 30 Jul 2025 03:03:46 EDT https://www.sciencedaily.com/releases/2025/07/250730030346.htm https://www.sciencedaily.com/releases/2025/07/250724040505.htm A new study reveals that swapping a typical nighttime carbohydrate snack for pistachios may beneficially alter gut bacteria in people with prediabetes. Conducted by Penn State researchers, the 12-week clinical trial found that pistachio consumption increased beneficial gut microbes like Roseburia and reduced harmful ones such as Blautia hydrogenotrophica. These microbiome changes could potentially support metabolic health and slow the progression to Type 2 diabetes. While more research is needed to confirm health outcomes, this study positions pistachios as a promising late-night snack with microbiome-boosting potential. Thu, 24 Jul 2025 23:20:00 EDT https://www.sciencedaily.com/releases/2025/07/250724040505.htm https://www.sciencedaily.com/releases/2025/06/250609020625.htm A rare genetic disorder called Werner syndrome causes premature aging and devastating health complications from an early age, yet treatment options have been lacking. New hope emerges from Chiba University, where researchers conducted the first clinical trial using nicotinamide riboside (NR), a precursor to NAD+ that s been linked to anti-aging effects. The double-blind trial revealed that NR not only safely boosted NAD+ levels but also improved cardiovascular health, reduced skin ulcers, and helped protect kidney function in patients. Mon, 09 Jun 2025 02:06:25 EDT https://www.sciencedaily.com/releases/2025/06/250609020625.htm https://www.sciencedaily.com/releases/2025/05/250521124626.htm New research demonstrates how specially engineered bacteria taken orally can operate as a delivery system for vaccines and antiviral therapies. Wed, 21 May 2025 12:46:26 EDT https://www.sciencedaily.com/releases/2025/05/250521124626.htm https://www.sciencedaily.com/releases/2025/05/250519131815.htm A study has become the first in the world to unravel the immediate effects of a high-fat diet on our gut health. Mon, 19 May 2025 13:18:15 EDT https://www.sciencedaily.com/releases/2025/05/250519131815.htm https://www.sciencedaily.com/releases/2025/05/250519131258.htm Feeding the gut acetate, paired with the right Bacteroides bacteria, led mice to shed fat without losing muscle. The combo pushed their metabolism into fat-burning mode, similar to fasting or a keto diet. Tests showed the effect vanished without gut bacteria, proving microbes are essential. Researchers now hope this discovery could inspire new obesity-fighting foods. Mon, 19 May 2025 13:12:58 EDT https://www.sciencedaily.com/releases/2025/05/250519131258.htm https://www.sciencedaily.com/releases/2025/05/250506131151.htm Researchers show how mice fed a Western-style diet are not able to rebuild a 'healthy,' diverse gut microbiome following antibiotic treatment. These mice were also more susceptible to infection by pathogens like Salmonella. However, mice given food loosely mimicking a Mediterranean diet -- high in plant-based fiber from fruits, vegetables, and whole grains -- were able to quickly restore a healthy and resilient gut microbiome after antibiotics. Tue, 06 May 2025 13:11:51 EDT https://www.sciencedaily.com/releases/2025/05/250506131151.htm https://www.sciencedaily.com/releases/2025/05/250501164002.htm A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments. The proof-of-concept study introduced a mechanism called 'GlycoCaging' that releases medicine exclusively to the lower gut at doses up to 10 times lower than current therapies. Thu, 01 May 2025 16:40:02 EDT https://www.sciencedaily.com/releases/2025/05/250501164002.htm https://www.sciencedaily.com/releases/2025/05/250501163952.htm After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of 'good' microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases. Thu, 01 May 2025 16:39:52 EDT https://www.sciencedaily.com/releases/2025/05/250501163952.htm https://www.sciencedaily.com/releases/2025/05/250501122047.htm Scientists inserted DNA-encoding methylmercury detoxification enzymes into the genome of an abundant human gut bacterium. The engineered bacterium detoxified methylmercury in the gut of mice and dramatically reduced the amount that reached other tissues, such as the brain and liver. Mice given an oral probiotic containing the engineered microbe and fed a diet high in bluefin tuna had much lower methylmercury levels than expected, suggesting that a probiotic might eventually make it safer for people to consume fish. Researchers performed the tests using pregnant mice and found lower levels of methylmercury in both maternal and fetal tissues, and lower signs of mercury toxicity in the fetal brain. Thu, 01 May 2025 12:20:47 EDT https://www.sciencedaily.com/releases/2025/05/250501122047.htm https://www.sciencedaily.com/releases/2025/04/250430142243.htm Protein sources appear to have major effects on both the population and function of the mouse gut microbiome. Wed, 30 Apr 2025 14:22:43 EDT https://www.sciencedaily.com/releases/2025/04/250430142243.htm https://www.sciencedaily.com/releases/2025/04/250428221206.htm Scientists built a model that allows them to diminish phage communities from a mouse gut microbiome -- and then bring them back -- without affecting the bacteria. On a test run of their model, researchers found evidence that phages may increase gut bacteria's sensitivity to antibiotics. Mon, 28 Apr 2025 22:12:06 EDT https://www.sciencedaily.com/releases/2025/04/250428221206.htm https://www.sciencedaily.com/releases/2025/04/250423163917.htm The global burden of chronic kidney disease (CKD) is rising, with more than 800 million people affected worldwide. Vascular diseases in patients with CKD are unique and grouped as uremic vascular diseases. One of them, calciphylaxis, typically affects patients with end-stage, advanced kidney disease. It is a condition characterized by severe, painful and non-healing skin ulcers with no known cure. Researchers have now discovered a novel biological pathway, called the IL6 pathway, central to the skin lesion initiation and progression. Blocking this pathway they believe, will likely prevent progression of the skin ulcers and resolve the pain seen in patients with calciphylaxis. Wed, 23 Apr 2025 16:39:17 EDT https://www.sciencedaily.com/releases/2025/04/250423163917.htm https://www.sciencedaily.com/releases/2025/04/250423120659.htm Scientists have discovered a surprising new connection between gut health and blood cancer risk one that could transform how we think about aging, inflammation, and the early stages of leukemia. Wed, 23 Apr 2025 12:06:59 EDT https://www.sciencedaily.com/releases/2025/04/250423120659.htm https://www.sciencedaily.com/releases/2025/04/250416135743.htm Researchers have made significant advancements in understanding the earliest stages of stomach cancer, a leading cause of cancer-related deaths worldwide, through two recent innovative studies. With a prevalence rates particularly high in East Asia, including China, this cancer often stems from chronic inflammation caused by Helicobacter pylori infection, which affects approximately 15% of the Hong Kong population. This inflammation can lead to a pre-cancerous stage known as intestinal metaplasia. The innovative studies have uncovered crucial insights into the earliest changes in the stomach that contribute to the development of stomach cancer, laying the foundation for improved prevention and early detection, ultimately saving lives. Wed, 16 Apr 2025 13:57:43 EDT https://www.sciencedaily.com/releases/2025/04/250416135743.htm https://www.sciencedaily.com/releases/2025/04/250415183436.htm Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study. Tue, 15 Apr 2025 18:34:36 EDT https://www.sciencedaily.com/releases/2025/04/250415183436.htm https://www.sciencedaily.com/releases/2025/04/250407172925.htm Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers show this is an auxiliary function. By maintaining basal levels of genetic activity when the network is in its OFF state, these genes ensure the bacteria remain fit and adaptable to their highly variable environment in the gut. Mon, 07 Apr 2025 17:29:25 EDT https://www.sciencedaily.com/releases/2025/04/250407172925.htm https://www.sciencedaily.com/releases/2025/04/250407114534.htm Scientists have discovered how a diarrhea-causing strain of bacteria uses 'molecular scissors' to cut open and destroy gut cells, leading to severe illness and sometimes death. Mon, 07 Apr 2025 11:45:34 EDT https://www.sciencedaily.com/releases/2025/04/250407114534.htm https://www.sciencedaily.com/releases/2025/04/250403122804.htm A new study shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective. Thu, 03 Apr 2025 12:28:04 EDT https://www.sciencedaily.com/releases/2025/04/250403122804.htm https://www.sciencedaily.com/releases/2025/04/250402122851.htm An AI model trained on large amounts of genetic data can predict whether bacteria will become antibiotic-resistant. The new study shows that antibiotic resistance is more easily transmitted between genetically similar bacteria and mainly occurs in wastewater treatment plants and inside the human body. Wed, 02 Apr 2025 12:28:51 EDT https://www.sciencedaily.com/releases/2025/04/250402122851.htm https://www.sciencedaily.com/releases/2025/04/250401151630.htm A new study examined whether a specialized diet could improve symptoms of gastrointestinal disorders linked to an imbalance in gut microbiota. Tue, 01 Apr 2025 15:16:30 EDT https://www.sciencedaily.com/releases/2025/04/250401151630.htm https://www.sciencedaily.com/releases/2025/03/250325114905.htm The pathogen C. diff -- the most common cause of health care-associated infectious diarrhea -- can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut. A team has discovered how C. diff (Clostridioides difficile) converts the poisonous compound 4-thiouracil, which could come from foods like broccoli, into a usable nutrient. Their findings increase understanding of the molecular drivers of C. diff infection and point to novel therapeutic strategies. Tue, 25 Mar 2025 11:49:05 EDT https://www.sciencedaily.com/releases/2025/03/250325114905.htm https://www.sciencedaily.com/releases/2025/03/250319143031.htm Scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new cause of stomach cancer that needs further research. Wed, 19 Mar 2025 14:30:31 EDT https://www.sciencedaily.com/releases/2025/03/250319143031.htm https://www.sciencedaily.com/releases/2025/03/250318141617.htm Researchers conducted a large-scale online survey of clinicians in the Asia-Pacific region to investigate treatment policies for the gastric cancer-causing bacteria Helicobacter pylori. Tue, 18 Mar 2025 14:16:17 EDT https://www.sciencedaily.com/releases/2025/03/250318141617.htm https://www.sciencedaily.com/releases/2025/03/250318141139.htm Increased antibiotic use can lead, seemingly paradoxically, to more problematic infections, as the bacteria evolve to resist the treatment. The answer to this antimicrobial resistance, which the Centers for Disease Control and Prevention called 'one of the world's most urgent public health problems,' might be a medication used for kidney disease, according to researchers. Tue, 18 Mar 2025 14:11:39 EDT https://www.sciencedaily.com/releases/2025/03/250318141139.htm