http://www.sciencedaily.com/news/plants_animals/molecular_biology/ Molecular biology. Read the latest research on molecular biology or search thousands of news articles with images from leading universities and research institutes. en-us Wed, 25 Nov 2009 05:05:01 EST Wed, 25 Nov 2009 05:05:01 EST 60 http://www.sciencedaily.com/images/logosmall.gif http://www.sciencedaily.com/news/plants_animals/molecular_biology/ For more science articles, visit ScienceDaily. http://www.sciencedaily.com/releases/2009/11/091114080604.htm Meiosis -- the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell -- is a major crossroads in all organisms reproducing sexually. Yet, how the cell precisely choreographs these chromosomal interactions is a long-standing question. New findings show that the cell's cytoskeleton, which moves things around in the cell, plays a critical role, essentially reaching into the nucleus to bring chromosome pairs together in preparation for recombination and segregation. Wed, 25 Nov 2009 14:00:00 EST http://www.sciencedaily.com/releases/2009/11/091114080604.htm http://www.sciencedaily.com/releases/2009/11/091124113611.htm Scientists have crystallized a protein that may help gut bacteria bind to the gastrointestinal tract. The protein could be used by probiotic producers to identify strains that are likely to be of real benefit to people. Wed, 25 Nov 2009 14:00:00 EST http://www.sciencedaily.com/releases/2009/11/091124113611.htm http://www.sciencedaily.com/releases/2009/11/091120124829.htm A key question in the origin of biological molecules like RNA and DNA is how they first came together billions of years ago from simple precursors. Now, researchers have reconstructed one of the earliest evolutionary steps yet: generating long chains of RNA from individual subunits using nothing but warm water. Wed, 25 Nov 2009 14:00:00 EST http://www.sciencedaily.com/releases/2009/11/091120124829.htm http://www.sciencedaily.com/releases/2009/11/091117094844.htm In order to effectively fight pathogens, even at remote areas of the human body, immune cells have to move quickly and in a flexible manner. Scientists have now deciphered the mechanism that illustrates how these mobile cells move on diverse surfaces. Wed, 25 Nov 2009 08:00:00 EST http://www.sciencedaily.com/releases/2009/11/091117094844.htm http://www.sciencedaily.com/releases/2009/11/091122095419.htm We've all read studies about the health benefits of having a life partner. The same thing is true at the molecular level, where amino acids known as cysteines are much more vulnerable to damage when single than when paired up with other cysteines. Wed, 25 Nov 2009 05:00:00 EST http://www.sciencedaily.com/releases/2009/11/091122095419.htm http://www.sciencedaily.com/releases/2009/11/091123094139.htm Researchers recently offered the sharpest-yet picture of how core biochemical pathways in skeletal muscle cells and fat cells are altered in people who suffer from insulin resistance -- a primary defect in type 2 diabetes and obesity. Taking a systems biology approach, the bioengineers and medical researchers also determined how a common class of drugs for treating insulin resistance -- TZDs -- alter these same core pathways. Wed, 25 Nov 2009 02:00:00 EST http://www.sciencedaily.com/releases/2009/11/091123094139.htm http://www.sciencedaily.com/releases/2009/11/091123132635.htm Two new studies reveal in unprecedented detail how the ribosome interacts with other molecules to assemble new proteins and guide them toward their destination in biological cells. The studies used molecular dynamics flexible fitting to examine the interaction of the ribosome with two prominent molecular partners. Tue, 24 Nov 2009 17:00:00 EST http://www.sciencedaily.com/releases/2009/11/091123132635.htm http://www.sciencedaily.com/releases/2009/11/091124121427.htm The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered using a state-of-the-art protein crystallography beamline at the Advanced Light Source. These protein motors play pivotal roles in gene expression and replication, and are vital to the survival of all biological cells, as well as infectious agents, such as the human papillomavirus, which has been linked to cervical cancer. Tue, 24 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091124121427.htm http://www.sciencedaily.com/releases/2009/11/091120094743.htm Bacteria possess an ingenious mechanism for preventing oxygen from harming the building blocks of the cell, according to new research. Mon, 23 Nov 2009 17:00:00 EST http://www.sciencedaily.com/releases/2009/11/091120094743.htm http://www.sciencedaily.com/releases/2009/11/091116103838.htm Is the indefinite self-renewal of adult cells possible without recourse to stem cell intermediates? Scientists have shown that it is possible, by achieving the ex vivo regeneration of macrophages, specialized cells in the immune system, over several months. Mon, 23 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091116103838.htm http://www.sciencedaily.com/releases/2009/11/091119193933.htm A team of scientists has taken a large step toward unraveling how regulatory proteins control the production of gene products during development and growth. They focused specifically on the complex process of producing red blood cells (erythrocytes). These cells contain large amounts of hemoglobin, a molecule essential for transporting oxygen throughout the body. The research results could help in the development of important new therapies to combat sickle-cell disease. Mon, 23 Nov 2009 02:00:00 EST http://www.sciencedaily.com/releases/2009/11/091119193933.htm http://www.sciencedaily.com/releases/2009/11/091120000553.htm In winemaking, grape juice is turned to wine during the fermentation process by the action of a number of essential beneficial microorganisms -- namely, bacteria. Sometimes, though, harmful bacteria also populate the fermentation vat, spoiling the wine in the process. A researcher in Finland has developed new methods based on DNA identification for rapidly and accurately identifying detrimental lactic acid bacteria and acetic acid bacteria during the earliest stages of the wine fermentation process. Mon, 23 Nov 2009 02:00:00 EST http://www.sciencedaily.com/releases/2009/11/091120000553.htm http://www.sciencedaily.com/releases/2009/11/091123114848.htm Two recent studies investigating the use of human umbilical cord blood stem cell (UCB) transplants for lung and heart disorders in animal models found beneficial results. When human UCB-derived mensenchymal cells were transplanted into newborn laboratory rats with induced oxygen-deprived injury, the effects of the injury lessened. A second study found that UCB mononuclear cells transplanted into sheep with a right ventricular malfunction beneficially altered the malfunction and enhanced diastolic function. Mon, 23 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091123114848.htm http://www.sciencedaily.com/releases/2009/11/091106145254.htm Plasmids, which are DNA molecules capable of independent replication in cells, have played an important role in gene technology. Researchers have now demonstrated that plasmid-based methods, which had been limited to single-cell organisms such as bacteria and yeasts, can be extended to mosses, opening the door to applications of a number of powerful techniques in plant research. Sun, 22 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091106145254.htm http://www.sciencedaily.com/releases/2009/11/091119085216.htm Bird flu viruses would have to make at least two simultaneous genetic mutations before they could be transmitted readily from human to human, according to new research. Sat, 21 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091119085216.htm http://www.sciencedaily.com/releases/2009/11/091119141217.htm Since the discovery in 2007 that a component of human semen called SEVI boosts infectivity of the virus that causes AIDS, researchers have been trying to learn more about SEVI and how it works, in hopes of thwarting its infection-promoting activity. Sat, 21 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091119141217.htm http://www.sciencedaily.com/releases/2009/11/091119111413.htm Scientists have described for the first time how the telomeres and adjacent sequences of the oyster fungus are organized. Sat, 21 Nov 2009 05:00:00 EST http://www.sciencedaily.com/releases/2009/11/091119111413.htm http://www.sciencedaily.com/releases/2009/11/091116165741.htm Scientists have discovered that a dietary antioxidant found in such vegetables as broccoli and cauliflower protects cells from damage caused by chemicals generated during the body's inflammatory response to infection and injury. The finding has implications for such inflammation-based disorders as cystic fibrosis, diabetes, heart disease and neurodegeneration. Fri, 20 Nov 2009 23:00:00 EST http://www.sciencedaily.com/releases/2009/11/091116165741.htm http://www.sciencedaily.com/releases/2009/11/091119101207.htm A nutritionist in Nigeria says that malnutrition and iron deficiency in schoolchildren could be reduced in her country by baking up snail pie. She explains snail is not only cheaper and more readily available than beef but contains more protein. Fri, 20 Nov 2009 17:00:00 EST http://www.sciencedaily.com/releases/2009/11/091119101207.htm http://www.sciencedaily.com/releases/2009/11/091118143255.htm Breakthrough research done earlier this year by a plant cell biologist has greatly accelerated scientists' knowledge on how plants and crops can survive difficult environmental conditions like drought. In drought conditions certain receptor proteins in plants perceive ABA, causing them to inhibit an enzyme called a phosphatase. The receptor protein is at the top of a signaling pathway in plants, functioning like a boss relaying orders to the team below that then executes particular decisions in the cell. Now recent published studies show how those orders are relayed at the molecular level. Fri, 20 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091118143255.htm http://www.sciencedaily.com/releases/2009/11/091119193936.htm Scientists have identified and grouped the genes thought to be responsible for cell wall development in maize, an effort that expands their ability to discover ways to produce the biomass best suited for biofuels production. Fri, 20 Nov 2009 08:00:00 EST http://www.sciencedaily.com/releases/2009/11/091119193936.htm http://www.sciencedaily.com/releases/2009/11/091116163210.htm A modified soybean oil increased the level of an omega-3 fatty acid in humans more than regular soybean oil. The modified oil may provide a plant-based alternative source of omega-3s. However, the oil's health effectiveness as a food ingredient remains to be proven. Thu, 19 Nov 2009 23:00:00 EST http://www.sciencedaily.com/releases/2009/11/091116163210.htm http://www.sciencedaily.com/releases/2009/11/091119111410.htm A protein found in the saliva of ticks helps protect mice from developing Lyme disease, researchers have discovered. The findings may spur development of a new vaccine against infection from Lyme disease, which is spread through tick bites. Thu, 19 Nov 2009 20:00:00 EST http://www.sciencedaily.com/releases/2009/11/091119111410.htm http://www.sciencedaily.com/releases/2009/11/091118143221.htm Viruses are well known for attacking humans and animals, but some viruses instead attack bacteria. Researchers are exploring how hungry viruses, armed with transformer-like weapons, attack bacteria, which may aid in the treatment of bacterial infections. Thu, 19 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091118143221.htm http://www.sciencedaily.com/releases/2009/11/091118160357.htm Biologists and engineers have dramatically improved the speed and accuracy of measuring an enigmatic set of proteins that influences almost every aspect of how cells and tissues function. The new method offers a long-sought tool for studying stem cells, cancer and other problems of fundamental importance to biology and medicine. Thu, 19 Nov 2009 08:00:00 EST http://www.sciencedaily.com/releases/2009/11/091118160357.htm http://www.sciencedaily.com/releases/2009/11/091116165633.htm Scientists have shown how plants can protect themselves against genetic damage caused by environmental stresses. The growing tips of plant roots and shoots have an in-built mechanism that, if it detects damage to the DNA, causes the cell to "commit suicide" rather than pass on its defective DNA. Wed, 18 Nov 2009 23:00:00 EST http://www.sciencedaily.com/releases/2009/11/091116165633.htm http://www.sciencedaily.com/releases/2009/11/091118161639.htm Researchers have uncovered the genetic identity of a cellular receptor for the immune system's first-response antibody, a discovery that sheds new light on infection control and immune disorders. The discovery is such a crucial part of immunology that the researchers are asking that the gene linked to this antibody receptor be renamed to better describe its role in early immune responses. Wed, 18 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091118161639.htm http://www.sciencedaily.com/releases/2009/11/091118101401.htm The regulating protein Srebp2 drives cholesterol formation, which prions need for their propagation, in prion-infected neuronal cells. Scientists anticipate new approaches in drug development to combat prion infection, as a result of these new findings Wed, 18 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091118101401.htm http://www.sciencedaily.com/releases/2009/11/091112103413.htm The AIDS virus inserts its genetic material into the genome of the infected cell. Scientists have now shown for the first time that the virus almost entirely spares particular sites in the human genetic material in this process. This finding may be useful for developing new, specific AIDS drugs. Mon, 16 Nov 2009 23:00:00 EST http://www.sciencedaily.com/releases/2009/11/091112103413.htm http://www.sciencedaily.com/releases/2009/11/091112121559.htm Structural biologists have described the architecture of the complex of protein units that make up the coat surrounding the HIV genome and identified in it a "seam" of functional importance that previously went unrecognized. Those findings could point the way to new treatments for blocking HIV infection. Fri, 13 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091112121559.htm http://www.sciencedaily.com/releases/2009/11/091110171654.htm A plant pathology scientist was researching the molecular basis of bacterial diseases of rice when he discovered how a group of proteins from plant pathogenic bacteria interact with DNA in the plant cell, opening up the possibility for what the scientist calls a "cascade of advances." Fri, 13 Nov 2009 05:00:00 EST http://www.sciencedaily.com/releases/2009/11/091110171654.htm http://www.sciencedaily.com/releases/2009/11/091113083307.htm Coral reefs live in some of the most nutrient deficient waters on the planet, so how do they survive? Marine biologists have discovered that certain sponges could be the key to reef survival. They recycle dissolved organic carbon that is unavailable to other reef residents. Fri, 13 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091113083307.htm http://www.sciencedaily.com/releases/2009/11/091111123618.htm Scientists in Washington, DC, are reporting development and successful tests of a new way for exploring the insides of living cells, the microscopic building blocks of all known plants and animals. They explode the cell while it is still living inside a plant or animal, vaporize its contents, and sniff. Thu, 12 Nov 2009 20:00:00 EST http://www.sciencedaily.com/releases/2009/11/091111123618.htm http://www.sciencedaily.com/releases/2009/11/091111130942.htm If humans are genetically related to chimps, why did our brains develop the innate ability for language and speech while theirs did not? Scientists suspect that part of the answer to the mystery lies in a gene called FOXP2. When mutated, FOXP2 can disrupt speech and language in humans. Now, a new study reveals major differences between how the human and chimp versions of FOXP2 work, perhaps explaining why language is unique to humans. Thu, 12 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091111130942.htm http://www.sciencedaily.com/releases/2009/11/091104123029.htm Engineering researchers have fabricated a palm-sized, automated, micro-injector that can insert proteins, DNA and other biomolecules into individual cells at volumes exponentially higher than current procedures, and at a fraction of the cost. This will allow scientists to vastly increase preclinical trials for drug development and genetic engineering, and provide greater control of the process. Thu, 12 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091104123029.htm http://www.sciencedaily.com/releases/2009/11/091111121249.htm Got food poisoning? The cause might be bacterial spores, en extremely hardy survival form of bacteria, a nightmare for health care and the food industry and an enigma for scientists. Spore-forming bacteria, present almost everywhere in our environment, can also cause serious infectious diseases, such as tetanus, anthrax, and botulism. Now researchers have made a breakthrough in our understanding of the molecular characteristics of spores that in the long term may lead to new methods for sterilizing food and medical equipment. Thu, 12 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091111121249.htm http://www.sciencedaily.com/releases/2009/10/091029151449.htm Using novel techniques, a Dutch researcher has cast new light on the replication of coronaviruses, a family of viruses including the cause of SARS. He has shown, using luminescent viruses, how coronaviruses use host cells and how we can use the intracellular processes to attack the virus. Tue, 10 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/10/091029151449.htm http://www.sciencedaily.com/releases/2009/11/091102171419.htm The search for the holy grail of regenerative medicine -- the ability to "grow back" a perfect body part when one is lost to injury or disease -- has been under way for years, yet the steps involved in this seemingly magic process are still poorly understood. Now researchers have identified an essential cellular pathway in zebrafish that paves the way for limb regeneration by unlocking gene expression patterns last seen during embryonic development. Tue, 10 Nov 2009 05:00:00 EST http://www.sciencedaily.com/releases/2009/11/091102171419.htm http://www.sciencedaily.com/releases/2009/11/091106112119.htm A shot of espresso may rev you up in the morning, but the downside is that it may also ramp up levels of bad cholesterol due to its effects on a unique liver protein called PXR. New research now shows that when chronically activated, the protein rejiggers how cholesterol is broken down in and cleared from the liver, a disturbance that can lead to high levels of the waxy substance or worse, full-blown atherosclerosis. Mon, 09 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091106112119.htm http://www.sciencedaily.com/releases/2009/11/091105092615.htm The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult cells, according to new research. Mon, 09 Nov 2009 08:00:00 EST http://www.sciencedaily.com/releases/2009/11/091105092615.htm http://www.sciencedaily.com/releases/2009/08/090828103930.htm Researchers in Spain have found that several species of lupins from the mountains of Andalusia have a protein content similar to that of other cultivated legumes. Mon, 09 Nov 2009 02:00:00 EST http://www.sciencedaily.com/releases/2009/08/090828103930.htm http://www.sciencedaily.com/releases/2009/11/091109121207.htm A chemical culprit responsible for the rapid, mysterious death of phytoplankton in the North Atlantic Ocean has been found. This same chemical may hold unexpected promise in cancer research. Mon, 09 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091109121207.htm http://www.sciencedaily.com/releases/2009/11/091109121115.htm Scientists have discovered that the key to plants' responses to drought lies in the structure of a protein called PYR1 and how it interacts with the plant hormone abscisic acid. Their study could open up new approaches to increasing crops' resistance to water shortage. Mon, 09 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091109121115.htm http://www.sciencedaily.com/releases/2009/11/091106145300.htm Researchers have discovered a fungal protein that plays a key role in causing disease in plants and animals and which also shields the pathogen from oxidative stress. Sun, 08 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091106145300.htm http://www.sciencedaily.com/releases/2009/11/091104132700.htm Technological advance in the study of gene expression and regulation in the genome's 3-D folding and looping state through the development of a novel technology. Sun, 08 Nov 2009 11:00:00 EST http://www.sciencedaily.com/releases/2009/11/091104132700.htm http://www.sciencedaily.com/releases/2009/10/091019122840.htm Researchers have previously been able to analyse which sugar structures are to be found on certain proteins, but not exactly where on the protein they are positioned. Fri, 06 Nov 2009 05:00:00 EST http://www.sciencedaily.com/releases/2009/10/091019122840.htm http://www.sciencedaily.com/releases/2009/11/091106102548.htm What is the role of proteins called polycystins in patients with polycystic kidney disease? Scientists have elucidated the molecular and cellular mechanisms linked to polycystin malfunctions that cause this common hereditary disease. Fri, 06 Nov 2009 00:00:00 EST http://www.sciencedaily.com/releases/2009/11/091106102548.htm http://www.sciencedaily.com/releases/2009/11/091104132702.htm New insight into how nature handles some fundamental processes is guiding researchers in the design of tailor-made proteins for applications such as artificial photosynthetic centers, long-range electron transfers, and fuel-cell catalysts for energy conversion. Thu, 05 Nov 2009 23:00:00 EST http://www.sciencedaily.com/releases/2009/11/091104132702.htm