Science News
from research organizations

Pet exposure may reduce allergy and obesity

Research shows having a dog early in life may alter gut bacteria in immune-boosting ways

Date:
April 6, 2017
Source:
University of Alberta Faculty of Medicine & Dentistry
Summary:
If you need a reason to become a dog lover, how about their ability to help protect kids from allergies and obesity? A new study showed that babies from families with pets -- 70 per cent of which were dogs -- showed higher levels of two types of microbes associated with lower risks of allergic disease and obesity.
Share:
FULL STORY

A German shepherd dog licking a baby's face.
Credit: © Christin Lola / Fotolia

If you need a reason to become a dog lover, how about their ability to help protect kids from allergies and obesity?

A new University of Alberta study showed that babies from families with pets -- 70 per cent of which were dogs -- showed higher levels of two types of microbes associated with lower risks of allergic disease and obesity.

But don't rush out to adopt a furry friend just yet.

"There's definitely a critical window of time when gut immunity and microbes co-develop, and when disruptions to the process result in changes to gut immunity," said Anita Kozyrskyj, a U of A pediatric epidemiologist and one of the world's leading researchers on gut microbes -- microorganisms or bacteria that live in the digestive tracts of humans and animals.

The latest findings from Kozyrskyj and her team's work on fecal samples collected from infants registered in the Canadian Healthy Infant Longitudinal Development study build on two decades of research that show children who grow up with dogs have lower rates of asthma.

The theory is that exposure to dirt and bacteria early in life -- for example, in a dog's fur and on its paws -- can create early immunity, though researchers aren't sure whether the effect occurs from bacteria on the furry friends or from human transfer by touching the pets, said Kozyrskyj.

Her team of 12, including study co-author and U of A post-doctoral fellow Hein Min Tun, take the science one step closer to understanding the connection by identifying that exposure to pets in the womb or up to three months after birth increases the abundance of two bacteria, Ruminococcus and Oscillospira, which have been linked with reduced childhood allergies and obesity, respectively.

"The abundance of these two bacteria were increased twofold when there was a pet in the house," said Kozyrskyj, adding that the pet exposure was shown to affect the gut microbiome indirectly -- from dog to mother to unborn baby -- during pregnancy as well as during the first three months of the baby's life. In other words, even if the dog had been given away for adoption just before the woman gave birth, the healthy microbiome exchange could still take place.

The study also showed that the immunity-boosting exchange occurred even in three birth scenarios known for reducing immunity, as shown in Kozyrskyj's previous work: C-section versus vaginal delivery, antibiotics during birth and lack of breastfeeding.

What's more, Kozyrskyj's study suggested that the presence of pets in the house reduced the likelihood of the transmission of vaginal GBS (group B Strep) during birth, which causes pneumonia in newborns and is prevented by giving mothers antibiotics during delivery.

It's far too early to predict how this finding will play out in the future, but Kozyrskyj doesn't rule out the concept of a "dog in a pill" as a preventive tool for allergies and obesity.

"It's not far-fetched that the pharmaceutical industry will try to create a supplement of these microbiomes, much like was done with probiotics," she said.


Story Source:

Materials provided by University of Alberta Faculty of Medicine & Dentistry. Note: Content may be edited for style and length.


Journal Reference:

  1. Hein M. Tun, Theodore Konya, Tim K. Takaro, Jeffrey R. Brook, Radha Chari, Catherine J. Field, David S. Guttman, Allan B. Becker, Piush J. Mandhane, Stuart E. Turvey, Padmaja Subbarao, Malcolm R. Sears, James A. Scott, Anita L. Kozyrskyj. Exposure to household furry pets influences the gut microbiota of infant at 3–4 months following various birth scenarios. Microbiome, 2017; 5 (1) DOI: 10.1186/s40168-017-0254-x

Cite This Page:

University of Alberta Faculty of Medicine & Dentistry. "Pet exposure may reduce allergy and obesity: Research shows having a dog early in life may alter gut bacteria in immune-boosting ways." ScienceDaily. ScienceDaily, 6 April 2017. <www.sciencedaily.com/releases/2017/04/170406143845.htm>.
University of Alberta Faculty of Medicine & Dentistry. (2017, April 6). Pet exposure may reduce allergy and obesity: Research shows having a dog early in life may alter gut bacteria in immune-boosting ways. ScienceDaily. Retrieved April 24, 2017 from www.sciencedaily.com/releases/2017/04/170406143845.htm
University of Alberta Faculty of Medicine & Dentistry. "Pet exposure may reduce allergy and obesity: Research shows having a dog early in life may alter gut bacteria in immune-boosting ways." ScienceDaily. www.sciencedaily.com/releases/2017/04/170406143845.htm (accessed April 24, 2017).