https://www.sciencedaily.com/news/health_medicine/diabetes/ Learn about early diabetes symptoms, diabetic diet information, diabetes care, type 1 diabetes, insulin resistance and type 2 diabetes. Read the latest medical research on diabetes. en-us Wed, 22 Apr 2026 09:22:53 EDT Wed, 22 Apr 2026 09:22:53 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/health_medicine/diabetes/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/03/260330210905.htm Deep sleep does far more than rest the body — it activates a powerful brain-driven system that controls growth hormone, fueling muscle and bone strength, metabolism, and even mental performance. Scientists have now mapped the neural circuits behind this process, uncovering a delicate feedback loop in which sleep boosts growth hormone, and that same hormone helps regulate wakefulness. Mon, 30 Mar 2026 21:39:42 EDT https://www.sciencedaily.com/releases/2026/03/260330210905.htm https://www.sciencedaily.com/releases/2026/03/260303050624.htm Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control. Tue, 03 Mar 2026 11:33:04 EST https://www.sciencedaily.com/releases/2026/03/260303050624.htm https://www.sciencedaily.com/releases/2026/01/260129080432.htm Researchers have discovered how pancreatic cancer reprograms its surroundings to spread quickly and stealthily. By using a protein called periostin, the tumor remodels nearby tissue and invades nerves, which helps cancer cells travel and form metastases. This process also creates a tough, fibrous barrier that makes treatments less effective. Targeting periostin could help stop this invasion before it starts. Fri, 30 Jan 2026 07:44:14 EST https://www.sciencedaily.com/releases/2026/01/260129080432.htm https://www.sciencedaily.com/releases/2026/01/260114084129.htm Pancreatic cancer uses a sugar-coated disguise to evade the immune system, helping explain why it’s so hard to treat. Northwestern scientists discovered this hidden mechanism and created an antibody that strips away the tumor’s protective signal. In animal tests, immune cells sprang back into action and tumors grew much more slowly. The team is now refining the therapy for future human trials. Thu, 15 Jan 2026 02:10:05 EST https://www.sciencedaily.com/releases/2026/01/260114084129.htm https://www.sciencedaily.com/releases/2025/09/250922074954.htm Researchers found that pancreatic pre-cancer cells mimic dementia by forming clumps of proteins due to faulty recycling processes. These insights could shed light on why pancreatic cancer develops so aggressively and why it is difficult to treat. By studying overlaps with neurological diseases, scientists hope to identify new strategies for prevention and treatment. Mon, 22 Sep 2025 23:30:44 EDT https://www.sciencedaily.com/releases/2025/09/250922074954.htm https://www.sciencedaily.com/releases/2025/09/250908175446.htm UC Berkeley researchers mapped the brain circuits that control growth hormone during sleep, uncovering a feedback system where sleep fuels hormone release, and the hormone regulates wakefulness. The discovery helps explain links between poor sleep, obesity, diabetes, and cognitive decline, while opening new paths for treating sleep and metabolic disorders. Mon, 08 Sep 2025 22:23:46 EDT https://www.sciencedaily.com/releases/2025/09/250908175446.htm https://www.sciencedaily.com/releases/2025/07/250709091705.htm MIT engineers have developed a tiny implantable device that could revolutionize emergency treatment for people with Type 1 diabetes. The device contains a powdered form of glucagon and can be remotely triggered—either manually or automatically by a glucose monitor—to release the hormone when blood sugar drops too low. This offers a potentially life-saving safety net, especially during sleep or for young children. Thu, 10 Jul 2025 10:00:04 EDT https://www.sciencedaily.com/releases/2025/07/250709091705.htm https://www.sciencedaily.com/releases/2025/05/250508161144.htm Cryptic peptides, which are expressed in pancreatic cancer cells, could be promising targets for T-cell therapies that attack pancreatic tumors, according to a new study. Thu, 08 May 2025 16:11:44 EDT https://www.sciencedaily.com/releases/2025/05/250508161144.htm https://www.sciencedaily.com/releases/2025/05/250506105340.htm Scientists say they have determined that low blood sugar, or hypoglycemia, may promote a breakdown of the blood-retinal barrier, an important boundary that regulates the flow of nutrients, waste and water in and out of the retina. Tue, 06 May 2025 10:53:40 EDT https://www.sciencedaily.com/releases/2025/05/250506105340.htm https://www.sciencedaily.com/releases/2025/04/250402122018.htm Scientists have found a way to 'intercept' pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to prevent pancreatic cancer from forming in the first place. Wed, 02 Apr 2025 12:20:18 EDT https://www.sciencedaily.com/releases/2025/04/250402122018.htm https://www.sciencedaily.com/releases/2025/03/250314170603.htm Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy. Fri, 14 Mar 2025 17:06:03 EDT https://www.sciencedaily.com/releases/2025/03/250314170603.htm https://www.sciencedaily.com/releases/2025/03/250310134303.htm A Japanese study has found that the use of continuous glucose monitoring (CGM) devices, equipped with sensors that alert diabetics when their blood sugar levels drop, can potentially make diabetic drivers safer on the road. Those who used the devices had lower incidences of low blood sugar and reported increased confidence in driving. Mon, 10 Mar 2025 13:43:03 EDT https://www.sciencedaily.com/releases/2025/03/250310134303.htm https://www.sciencedaily.com/releases/2025/02/250218113655.htm Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. Early detection of PC is the primary concern of most PC research, as it has the potential to make a substantial difference to the treatment and survival of patients. Survival rates, however, remain poor due to the vague nature of the symptoms associated with early-stage PC, and subsequently the late-stage of the disease at diagnosis. Now researchers are focusing on pancreatic cystic lesions to tackle the crucial issue of identifying patients who are at high-risk of developing pancreatic cancer, to improve survival rates. Tue, 18 Feb 2025 11:36:55 EST https://www.sciencedaily.com/releases/2025/02/250218113655.htm https://www.sciencedaily.com/releases/2025/02/250212151511.htm Researchers have proven that antibiotic-resistant strains of a harmful bacteria thrive in a diabetic infection environment. Wed, 12 Feb 2025 15:15:11 EST https://www.sciencedaily.com/releases/2025/02/250212151511.htm https://www.sciencedaily.com/releases/2025/02/250212151141.htm A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers. Wed, 12 Feb 2025 15:11:41 EST https://www.sciencedaily.com/releases/2025/02/250212151141.htm https://www.sciencedaily.com/releases/2025/02/250212134824.htm People with type 1 diabetes require continuous insulin treatment and must regularly measure their glucose levels. With open-loop therapies, insulin administration is manually controlled, while hybrid closed-loop systems automatically regulate insulin delivery. A study showed that hybrid closed-loop systems offer improved long-term blood sugar values (HbA1c levels) and a lower risk of hypoglycemic coma, but lead to a higher rate of diabetic ketoacidosis. Wed, 12 Feb 2025 13:48:24 EST https://www.sciencedaily.com/releases/2025/02/250212134824.htm https://www.sciencedaily.com/releases/2025/02/250207122748.htm Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies, and clues behind why these tumors don't respond to existing immunotherapies. Fri, 07 Feb 2025 12:27:48 EST https://www.sciencedaily.com/releases/2025/02/250207122748.htm https://www.sciencedaily.com/releases/2024/11/241111155232.htm A team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer development. Mon, 11 Nov 2024 15:52:32 EST https://www.sciencedaily.com/releases/2024/11/241111155232.htm https://www.sciencedaily.com/releases/2024/10/241017113538.htm The discovery of a gut-to-brain regulation pathway in flies calls for additional consideration on how certain medications, especially GLP-1 agonists, can be used to treat obesity and diabetes in humans. Thu, 17 Oct 2024 11:35:38 EDT https://www.sciencedaily.com/releases/2024/10/241017113538.htm https://www.sciencedaily.com/releases/2024/10/241002104539.htm People with diabetes take insulin to lower high blood sugar. However, if glucose levels plunge too low -- from taking too much insulin or not eating enough sugar -- people can experience hypoglycemia, which can lead to dizziness, cognitive impairment, seizures or comas. To prevent and treat this condition, researchers report encapsulating the hormone glucagon. In mouse trials, the nanocapsules activated when blood sugar levels dropped dangerously low and quickly restored glucose levels. Wed, 02 Oct 2024 10:45:39 EDT https://www.sciencedaily.com/releases/2024/10/241002104539.htm https://www.sciencedaily.com/releases/2024/09/240905120849.htm Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new study. The finding underscores the urgent need for advancements in diagnostic technology and staging, which could significantly alter early pancreatic cancer treatment and research. Thu, 05 Sep 2024 12:08:49 EDT https://www.sciencedaily.com/releases/2024/09/240905120849.htm https://www.sciencedaily.com/releases/2024/08/240822125859.htm Research in mice sheds light on how thyroid hormone alters wiring in the brain. Findings reveal that thyroid hormone syncs up the brain and body to drive exploratory behavior. Researchers say their work could illuminate new treatments for certain psychiatric conditions. Thu, 22 Aug 2024 12:58:59 EDT https://www.sciencedaily.com/releases/2024/08/240822125859.htm https://www.sciencedaily.com/releases/2024/08/240807122907.htm Researchers found a 'neuro-cancer axis' may promote spread of breast cancer. They also found that an FDA-approved anti-nausea medication may prevent it. Wed, 07 Aug 2024 12:29:07 EDT https://www.sciencedaily.com/releases/2024/08/240807122907.htm https://www.sciencedaily.com/releases/2024/07/240722155157.htm Scientists created new tools to study brain messenger proteins called neuropeptides in the brains of behaving animals, discovering they are the primary messengers in the fear circuit in mouse brains, and that multiple neuropeptides work together to achieve this--explaining why some clinical trials that target just one neuropeptide have failed. The new tools and findings can be used to direct drug development for fear-related neurological disorders like PTSD and anxiety, design better painkillers, and uncover new information for other neural circuits in the brain. Mon, 22 Jul 2024 15:51:57 EDT https://www.sciencedaily.com/releases/2024/07/240722155157.htm https://www.sciencedaily.com/releases/2024/06/240618152955.htm Researchers have developed a 3D genomic profiling technique to identify small precancerous lesions in the pancreas -- called pancreatic intraepithelial neoplasias (PanINs) -- that lead to one of the most aggressive, deadly pancreatic cancers. Tue, 18 Jun 2024 15:29:55 EDT https://www.sciencedaily.com/releases/2024/06/240618152955.htm https://www.sciencedaily.com/releases/2024/06/240618115702.htm An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer cells. Tue, 18 Jun 2024 11:57:02 EDT https://www.sciencedaily.com/releases/2024/06/240618115702.htm https://www.sciencedaily.com/releases/2024/06/240610171018.htm The cost of nutritious food and the lack of access to it are of significant concern to U.S. consumers. New public opinion poll and expert analysis reflect crucial need to make healthy food accessible to avert projected crisis in cardiovascular disease incidence, costs. Mon, 10 Jun 2024 17:10:18 EDT https://www.sciencedaily.com/releases/2024/06/240610171018.htm https://www.sciencedaily.com/releases/2024/06/240607121434.htm One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels. This is because in these insulin-resistant patients, glucose production by the liver is triggered, a process that is still full of questions for the scientific community. Now, a review article presents a comprehensive overview of the most important advances in understanding this mechanism. Fri, 07 Jun 2024 12:14:34 EDT https://www.sciencedaily.com/releases/2024/06/240607121434.htm https://www.sciencedaily.com/releases/2024/06/240605162500.htm Scientists developed a human pancreatic cancer fibrotic barrier 3D cell-culture model to assess treatments for pancreatic ductal adenocarcinoma. By targeting the ROCK2 pathway, they achieved a notable decrease in fibrosis and enhanced tissue permeability to drugs, offering promising avenues for overcoming treatment obstacles in pancreatic cancer. Wed, 05 Jun 2024 16:25:00 EDT https://www.sciencedaily.com/releases/2024/06/240605162500.htm https://www.sciencedaily.com/releases/2024/05/240508161316.htm Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a new study. Wed, 08 May 2024 16:13:16 EDT https://www.sciencedaily.com/releases/2024/05/240508161316.htm https://www.sciencedaily.com/releases/2024/02/240220144644.htm Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to new research. Tue, 20 Feb 2024 14:46:44 EST https://www.sciencedaily.com/releases/2024/02/240220144644.htm https://www.sciencedaily.com/releases/2024/02/240208122018.htm Based solely on driving behavior and head/gaze motion, the newly developed tool recognizes low blood sugar levels. Thu, 08 Feb 2024 12:20:18 EST https://www.sciencedaily.com/releases/2024/02/240208122018.htm https://www.sciencedaily.com/releases/2024/01/240119122649.htm Researchers have found a new way to supply the body with insulin. The medication that can be taken orally has already been tested on baboons, in which it was found to lower the blood sugar levels without causing hypoglycemia. The new insulin is ready to be tested on humans in 2025. If all goes well, diabetics are facing an easier life without injections. Fri, 19 Jan 2024 12:26:49 EST https://www.sciencedaily.com/releases/2024/01/240119122649.htm https://www.sciencedaily.com/releases/2024/01/240113143701.htm In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer. Sat, 13 Jan 2024 14:37:01 EST https://www.sciencedaily.com/releases/2024/01/240113143701.htm https://www.sciencedaily.com/releases/2023/12/231206115918.htm Researchers discovered how anti-cancer drugs called HDAC inhibitors help treat pancreatic cancer by altering scar tissue (fibroblast) development. The findings suggest HDAC inhibitors could be powerful tools in fighting pancreatic cancer -- alone and in combination with other therapies. Wed, 06 Dec 2023 11:59:18 EST https://www.sciencedaily.com/releases/2023/12/231206115918.htm https://www.sciencedaily.com/releases/2023/12/231204135202.htm Pregnancy brings a rise in pancreatic beta cells -- the cells that produce insulin. Shortly after birth, these cells return to their normal levels. The mechanisms behind this process had remained a mystery. But now a research group has revealed that white blood cells called macrophages 'eat' these cells.  Mon, 04 Dec 2023 13:52:02 EST https://www.sciencedaily.com/releases/2023/12/231204135202.htm https://www.sciencedaily.com/releases/2023/11/231128132322.htm Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve damage conditions, like Charcot Marie Tooth disease. Their findings may inspire novel therapeutics that bolster repair function and heal peripheral neuropathy -- even in hereditary and developmental cases. Tue, 28 Nov 2023 13:23:22 EST https://www.sciencedaily.com/releases/2023/11/231128132322.htm https://www.sciencedaily.com/releases/2023/11/231121175349.htm Researchers conducted a gene expression analysis at the single-cell level on pancreatic islets from prediabetic and diabetic mouse models. Analysis results revealed upregulation of Anxa10 expression in pancreatic beta cells during the early phases of diabetes, attributed to elevated blood glucose levels. This elevated Anxa10 expression was found to influence intracellular calcium homeostasis, leading to a reduction in insulin secretory capacity. Tue, 21 Nov 2023 17:53:49 EST https://www.sciencedaily.com/releases/2023/11/231121175349.htm https://www.sciencedaily.com/releases/2023/11/231116140835.htm A new scientific finding is the foundation for the first clinical trial in the U.S. to study an experimental drug's ability to fight pancreatic cancer with metastasis to the liver.   Thu, 16 Nov 2023 14:08:35 EST https://www.sciencedaily.com/releases/2023/11/231116140835.htm https://www.sciencedaily.com/releases/2023/11/231106134809.htm A huge step forward in understanding how neurons communicate through extremely short proteins called neuropeptides will help scientists understand how our emotions and mental states are controlled, as well as widespread neuropsychiatric conditions like eating disorders, OCD and PSTD.   Mon, 06 Nov 2023 13:48:09 EST https://www.sciencedaily.com/releases/2023/11/231106134809.htm https://www.sciencedaily.com/releases/2023/11/231102135130.htm In a new study, scientists show that their synthetic melanin, mimicking the natural melanin in human skin, can be applied topically to injured skin, where it accelerates wound healing. These effects occur both in the skin itself and systemically in the body. Thu, 02 Nov 2023 13:51:30 EDT https://www.sciencedaily.com/releases/2023/11/231102135130.htm https://www.sciencedaily.com/releases/2023/10/231031111538.htm The first detailed explanation of why people with obesity and Type 2 diabetes are at an increased risk of pancreatic cancer has been published. The research demonstrates that excessive insulin levels overstimulate pancreatic acinar cells, which produce digestive juices. This overstimulation leads to inflammation that converts these cells into precancerous cells. The researchers say the findings may have implications for other cancers associated with obesity and Type 2 diabetes, where elevated insulin levels may also play a contributing role in disease initiation. Tue, 31 Oct 2023 11:15:38 EDT https://www.sciencedaily.com/releases/2023/10/231031111538.htm https://www.sciencedaily.com/releases/2023/10/231018161853.htm A new study carried out in mice, has identified cells that drive the spread of pancreatic cancer and discovered a weakness in these cells that could be targeted using existing drugs. This offers a promising new approach for treating pancreatic cancer. Wed, 18 Oct 2023 16:18:53 EDT https://www.sciencedaily.com/releases/2023/10/231018161853.htm https://www.sciencedaily.com/releases/2023/09/230906112428.htm Scientists identified new set of molecules that drive the growth of human pancreatic cancer cell lines, explaining how genetic mutations can activate genetic 'super-enhancers' that promote out-of-control pancreatic cancer growth. They show the efficacy of an experimental drug that targets a super-enhancer related protein, demonstrating the promise of therapeutics that block the effects of super-enhancers. Wed, 06 Sep 2023 11:24:28 EDT https://www.sciencedaily.com/releases/2023/09/230906112428.htm https://www.sciencedaily.com/releases/2023/08/230811115439.htm The skin, hair and eye color of more than eight billion humans is determined by the light-absorbing pigment known as melanin. New research has identified 135 new genes associated with pigmentation. Fri, 11 Aug 2023 11:54:39 EDT https://www.sciencedaily.com/releases/2023/08/230811115439.htm https://www.sciencedaily.com/releases/2023/05/230518120849.htm Researchers have announced a major advance in understanding the fundamental structure of melanin and one of its components that turns light into heat, protecting the body from sun damage. Thu, 18 May 2023 12:08:49 EDT https://www.sciencedaily.com/releases/2023/05/230518120849.htm https://www.sciencedaily.com/releases/2023/04/230421195027.htm Researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little. Fri, 21 Apr 2023 19:50:27 EDT https://www.sciencedaily.com/releases/2023/04/230421195027.htm https://www.sciencedaily.com/releases/2023/04/230410111631.htm For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a new study shows. Researchers say the findings suggest that bariatric surgery likely enables the regeneration of the peripheral nerves and, therefore, may be an effective treatment for millions of individuals with obesity who are at risk of developing diabetes and peripheral neuropathy, Mon, 10 Apr 2023 11:16:31 EDT https://www.sciencedaily.com/releases/2023/04/230410111631.htm https://www.sciencedaily.com/releases/2023/02/230209114732.htm Microexons, tiny fragments of genes that are just 3-27 nucleotides long, are known to play a 'tiny but mighty' role in neuronal cells. Through RNA splicing, microexons sculpt the surfaces of proteins in a highly precise manner, performing microsurgery on the nervous system's proteins. According to a new study, microexons are also crucial for pancreatic function and regulating blood glucose levels. The microexons are located on more than a hundred genes, including some critical for insulin secretion and type-2 diabetes risk. The researchers believe the discovery could lead to new high-precision treatments for type-2 diabetes, for example by repurposing existing treatments that already exploit RNA splicing mechanisms to treat other types of diseases. Thu, 09 Feb 2023 11:47:32 EST https://www.sciencedaily.com/releases/2023/02/230209114732.htm https://www.sciencedaily.com/releases/2023/01/230125121553.htm The study adds to growing evidence that some often-underappreciated, 'non-essential' amino acids play important roles in the nervous system. The findings may provide a new way to identify people at high risk for peripheral neuropathy, as well as a potential treatment option. Wed, 25 Jan 2023 12:15:53 EST https://www.sciencedaily.com/releases/2023/01/230125121553.htm https://www.sciencedaily.com/releases/2022/12/221230142240.htm Researchers have discovered a novel immunotherapy combination, targeting checkpoints in both T cells and myeloid suppressor cells, that successfully reprogrammed the tumor immune microenvironment (TIME) and significantly improved anti-tumor responses in preclinical models of pancreatic cancer. Fri, 30 Dec 2022 14:22:40 EST https://www.sciencedaily.com/releases/2022/12/221230142240.htm https://www.sciencedaily.com/releases/2022/12/221206105900.htm A human factors engineer and health services researcher is developing and testing user-friendly health information tools and technology designed to enhance accessibility and value to older adults with both diabetes and Alzheimer's disease, and their caregivers. Without numerous finger sticks, these tools and technology will be designed to provide patients, caregivers, and clinicians with glucose metrics needed to diagnose hypoglycemia and identify treatment options. Tue, 06 Dec 2022 10:59:00 EST https://www.sciencedaily.com/releases/2022/12/221206105900.htm https://www.sciencedaily.com/releases/2022/11/221130114525.htm New research points to the inactivation of a previously unidentified gene as a likely culprit in the development of pancreatic cancer. The findings could alter the scientific understanding of this deadly disease and inform the establishment of novel treatments. Wed, 30 Nov 2022 11:45:25 EST https://www.sciencedaily.com/releases/2022/11/221130114525.htm https://www.sciencedaily.com/releases/2022/10/221027170415.htm Overall cancer death rates continued to decline among men, women, children, and adolescents and young adults in every major racial and ethnic group in the United States from 2015 to 2019, according to the latest Annual Report to the Nation on the Status of Cancer. Thu, 27 Oct 2022 17:04:15 EDT https://www.sciencedaily.com/releases/2022/10/221027170415.htm https://www.sciencedaily.com/releases/2022/10/221006141500.htm Researchers have discovered that the organization of different types of immune cells within pancreatic tumors is associated with how well patients with pancreatic cancer respond to treatment and how long they survive. Thu, 06 Oct 2022 14:15:00 EDT https://www.sciencedaily.com/releases/2022/10/221006141500.htm https://www.sciencedaily.com/releases/2022/10/221005111910.htm A molecular test called PancreaSeq accurately classifies pancreatic cysts as potentially cancerous or benign, according to a large, multi-center study. Wed, 05 Oct 2022 11:19:10 EDT https://www.sciencedaily.com/releases/2022/10/221005111910.htm https://www.sciencedaily.com/releases/2022/09/220929132540.htm Multiple lipid biomarkers are linked to the development of neuropathy in patients with type 2 diabetes, a new study finds. Participants with high scores for diabetic neuropathy had changes in lipids reflecting impaired energy metabolism. Researchers say the findings bring potential to identify those with the highest risk of developing disease and facilitate more focused management. Thu, 29 Sep 2022 13:25:40 EDT https://www.sciencedaily.com/releases/2022/09/220929132540.htm https://www.sciencedaily.com/releases/2022/09/220914102240.htm Treating mice models of insulin-dependent diabetes mellitus (a condition found primarily in type 1 diabetes) with a combination of leptin and a drug called PTP1B inhibitor, researchers found that blood glucose levels normalized without the use of insulin. Wed, 14 Sep 2022 10:22:40 EDT https://www.sciencedaily.com/releases/2022/09/220914102240.htm https://www.sciencedaily.com/releases/2022/09/220913110443.htm An artificial intelligence (AI) tool is highly effective at detecting pancreatic cancer on CT, according to a new study. Tue, 13 Sep 2022 11:04:43 EDT https://www.sciencedaily.com/releases/2022/09/220913110443.htm https://www.sciencedaily.com/releases/2022/09/220907105426.htm Detailed characterization of human pancreatic islets is key to elucidate the pathophysiology of all forms of diabetes mellitus, including its most common form known as type 2 diabetes (T2D). However, access to pancreatic islets is limited and pancreatic tissue for islet retrieval can be either obtained from cadaveric or brain-dead organ donors or from patients undergoing pancreatectomy, henceforth defined as living donors. Moreover, different protocols for procurement of islets substantially impact their molecular profiles and function. These factors coupled with heterogeneity among individuals result in analytical challenges to separate genuine disease pathology or differences between human donors from experimental noise. Wed, 07 Sep 2022 10:54:26 EDT https://www.sciencedaily.com/releases/2022/09/220907105426.htm