https://www.sciencedaily.com/news/health_medicine/leukemia/ Read the latest medical research and information on leukemia. Learn about the symptoms and diagnosis of chronic myeloid leukemia (CML) and other leukemia types. What new leukemia treatments are under development? en-us Thu, 15 Oct 2026 08:57:36 EDT Thu, 15 Oct 2026 08:57:36 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/health_medicine/leukemia/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/10/261007232940.htm Not all vitamin D supplements are created equal, and new research suggests that one popular form may have an unexpected downside. Scientists found that taking vitamin D2 can actually lower the body's levels of vitamin D3, the form naturally produced by sunlight and more effective at boosting overall vitamin D. Previous studies also suggest that vitamin D3 may provide stronger immune protection against viruses and bacteria. Thu, 08 Oct 2026 00:06:26 EDT https://www.sciencedaily.com/releases/2026/10/261007232940.htm https://www.sciencedaily.com/releases/2026/09/260930225501.htm A vitamin D analog may help break down pancreatic cancer’s protective defenses, potentially making tumors more vulnerable to chemotherapy and immune attack. A small clinical trial found encouraging responses, especially in patients whose tumors had high levels of the vitamin D receptor. Sat, 03 Oct 2026 23:10:23 EDT https://www.sciencedaily.com/releases/2026/09/260930225501.htm https://www.sciencedaily.com/releases/2026/09/260924020408.htm Researchers used CRISPR to remove CD33 from donor stem cells, potentially giving doctors a way to attack aggressive blood cancers without destroying the healthy cells patients need after a transplant. In a 30-patient trial, the edited cells successfully took hold and appeared to shield blood cells from a CD33-targeted cancer treatment. Fri, 25 Sep 2026 09:13:03 EDT https://www.sciencedaily.com/releases/2026/09/260924020408.htm https://www.sciencedaily.com/releases/2026/09/260914042053.htm Low vitamin D levels may make recovery from breast cancer surgery more painful, according to a study of 184 women undergoing mastectomy. Patients with vitamin D deficiency were three times more likely to experience moderate to severe pain during the first 24 hours after surgery and also used substantially more of the opioid painkiller tramadol. They received slightly more fentanyl during surgery and experienced more postoperative nausea as well. Mon, 14 Sep 2026 08:52:54 EDT https://www.sciencedaily.com/releases/2026/09/260914042053.htm https://www.sciencedaily.com/releases/2026/09/260904000326.htm Researchers have mapped breast tumors in striking detail and uncovered hidden pockets of dormant cancer cells that may help explain why cancer can return after treatment. Unlike rapidly dividing cells, these quiet cells can essentially hibernate, allowing them to evade chemotherapy and reactivate later. The team found that they are often surrounded by immune cells and connective tissue cells that may act like a protective shield. Sun, 06 Sep 2026 16:43:10 EDT https://www.sciencedaily.com/releases/2026/09/260904000326.htm https://www.sciencedaily.com/releases/2026/08/260829035227.htm Researchers have produced a form of Spirulina containing biologically active vitamin B12 at levels comparable to beef. By carefully controlling the light used to grow the algae, they overcame a major problem with conventional Spirulina, which mainly contains a form of B12 the human body cannot use. The carbon-neutral system could provide a more sustainable source of the essential vitamin. Sun, 30 Aug 2026 01:17:05 EDT https://www.sciencedaily.com/releases/2026/08/260829035227.htm https://www.sciencedaily.com/releases/2026/08/260827010507.htm The belief that huge doses of vitamin C can ward off colds was popularized more than 50 years ago by Nobel Prize winner Linus Pauling. Since then, larger studies have found that vitamin C does not prevent most people from catching a cold, although regularly taking it may make severe symptoms slightly shorter or milder. Thu, 27 Aug 2026 06:38:30 EDT https://www.sciencedaily.com/releases/2026/08/260827010507.htm https://www.sciencedaily.com/releases/2026/08/260813045554.htm A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesity paired with vitamin D deficiency was linked to a 123% higher risk of death over six years. Each condition was associated with increased risk on its own, but together they appeared to create a dangerous feedback loop, with belly fat reducing the amount of vitamin D available in the bloodstream while low vitamin D may worsen inflammation and other health problems. Thu, 13 Aug 2026 22:29:03 EDT https://www.sciencedaily.com/releases/2026/08/260813045554.htm https://www.sciencedaily.com/releases/2026/08/260806050717.htm Linus Pauling was widely mocked for claiming that vitamin C could fight cancer, especially after trials using vitamin C pills showed no benefit. Researchers now know that intravenous vitamin C reaches vastly higher concentrations and can behave more like an experimental cancer drug than an ordinary supplement. Early studies suggest it may damage vulnerable cancer cells, reduce treatment side effects, and possibly improve outcomes for some patients. Fri, 07 Aug 2026 09:02:16 EDT https://www.sciencedaily.com/releases/2026/08/260806050717.htm https://www.sciencedaily.com/releases/2026/06/260623083116.htm Vitamin B12 is needed in microscopic amounts, but a shortage can have major effects on health and energy. The vitamin was first linked to a lifesaving liver treatment for pernicious anemia nearly 100 years ago. Today, researchers are finding that B12 may also help keep cellular powerhouses called mitochondria functioning properly. This could explain why some people experience fatigue and brain fog even before traditional signs of deficiency show up. Thu, 25 Jun 2026 10:57:39 EDT https://www.sciencedaily.com/releases/2026/06/260623083116.htm https://www.sciencedaily.com/releases/2026/06/260623083104.htm A study of nearly 300 people across northern Britain found that vitamin D levels often stay low all year in groups most at risk. Surprisingly, summer sunshine did not significantly boost vitamin D levels among older adults or people from minoritized ethnic backgrounds. Wed, 24 Jun 2026 00:45:50 EDT https://www.sciencedaily.com/releases/2026/06/260623083104.htm https://www.sciencedaily.com/releases/2026/06/260623014006.htm A massive national study found that nearly half of Americans with kidney failure who are referred for a transplant never even begin the evaluation process, and only 19% make it onto the transplant waitlist. Researchers discovered that factors such as where a person lives, whether they are married, their income level, language, age, and even which transplant center they use can dramatically affect their chances of moving forward. Wed, 01 Jul 2026 16:10:45 EDT https://www.sciencedaily.com/releases/2026/06/260623014006.htm https://www.sciencedaily.com/releases/2026/06/260605023357.htm Scientists have successfully tested an AI-designed universal coronavirus vaccine in humans for the first time, finding it to be safe and well tolerated. The vaccine generated immune responses against multiple coronaviruses, including SARS-CoV-2, SARS, and related bat viruses with pandemic potential. By targeting features shared across an entire virus family, it aims to provide protection even as viruses evolve. Fri, 05 Jun 2026 11:42:19 EDT https://www.sciencedaily.com/releases/2026/06/260605023357.htm https://www.sciencedaily.com/releases/2026/05/260526233433.htm Scientists in Japan have created powerful new vitamin K-based compounds that may help the brain regenerate lost neurons — a breakthrough that could one day change how diseases like Alzheimer’s and Parkinson’s are treated. By combining vitamin K with components related to vitamin A, the researchers developed compounds that were about three times more effective at turning neural stem cells into neurons than natural vitamin K alone. Wed, 27 May 2026 00:02:46 EDT https://www.sciencedaily.com/releases/2026/05/260526233433.htm https://www.sciencedaily.com/releases/2026/05/260523021820.htm A surprising study suggests vitamin D2 supplements may reduce the body’s levels of vitamin D3 — the more effective form of vitamin D. Researchers found D3 not only boosts vitamin D status more efficiently, but may also play a unique role in helping the immune system fight off viruses and bacteria. The discovery is prompting scientists to rethink whether D3 should become the preferred choice for supplementation. Sat, 23 May 2026 02:18:20 EDT https://www.sciencedaily.com/releases/2026/05/260523021820.htm https://www.sciencedaily.com/releases/2026/05/260519224308.htm Low vitamin D levels could be quietly making breast cancer surgery recovery far more painful. In a new study, patients deficient in vitamin D were three times more likely to experience moderate to severe pain after mastectomy surgery and ended up using significantly more opioid medication to cope. Researchers say vitamin D may help regulate how the body processes pain through its effects on inflammation and the immune system. Tue, 19 May 2026 23:30:39 EDT https://www.sciencedaily.com/releases/2026/05/260519224308.htm https://www.sciencedaily.com/releases/2026/05/260515002158.htm Scientists have uncovered a surprising dark side to vitamin B2: it may help cancer cells stay alive. The vitamin supports a cellular shield that protects tumors from ferroptosis, a form of programmed cell death linked to cancer suppression. In lab tests, researchers used a vitamin B2-like compound called roseoflavin to break down that protection and trigger cancer cell death. Fri, 15 May 2026 07:44:45 EDT https://www.sciencedaily.com/releases/2026/05/260515002158.htm https://www.sciencedaily.com/releases/2026/04/260428004119.htm A daily vitamin D supplement may quietly supercharge chemotherapy. In a small study, women who took low doses alongside treatment were far more likely to see their cancer vanish than those who didn’t. Since vitamin D also supports immune function—and many patients are deficient—it could be playing a bigger role than expected. Scientists say this affordable approach deserves much deeper investigation. Tue, 28 Apr 2026 01:03:03 EDT https://www.sciencedaily.com/releases/2026/04/260428004119.htm https://www.sciencedaily.com/releases/2026/04/260407073850.htm Vitamin D levels in midlife may play a bigger role in long-term brain health than previously thought. In a study following nearly 800 people over 16 years, those with higher vitamin D levels in their 30s and 40s had lower levels of tau protein later on, a key marker linked to dementia. Tue, 07 Apr 2026 07:47:09 EDT https://www.sciencedaily.com/releases/2026/04/260407073850.htm https://www.sciencedaily.com/releases/2026/03/260317015933.htm mRNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA nanostructures to better control how the immune system responds. In early studies, it produced strong antibody and T cell responses in both mice and human models. Researchers say it could lead to more stable, easier-to-manufacture vaccines for diseases like COVID-19, HIV, and Ebola. Tue, 17 Mar 2026 01:59:33 EDT https://www.sciencedaily.com/releases/2026/03/260317015933.htm https://www.sciencedaily.com/releases/2026/03/260315001845.htm A major clinical trial has delivered an unexpected twist in the search for ways to fight COVID-19 and its lingering effects. Researchers at Mass General Brigham found that taking high doses of vitamin D3 did not make COVID-19 infections less severe or reduce hospital visits. However, the study uncovered a subtle but intriguing signal suggesting that people who consistently took vitamin D supplements might be slightly less likely to develop long COVID symptoms weeks after infection. Sun, 15 Mar 2026 05:54:54 EDT https://www.sciencedaily.com/releases/2026/03/260315001845.htm https://www.sciencedaily.com/releases/2026/03/260303050624.htm Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control. Tue, 03 Mar 2026 11:33:04 EST https://www.sciencedaily.com/releases/2026/03/260303050624.htm https://www.sciencedaily.com/releases/2026/02/260204114343.htm As bird flu continues to circulate in animals and spill over into humans, researchers are racing to stop it before it adapts to spread widely between people. A new nasal spray vaccine showed strong protection against H5N1 in animal tests, outperforming traditional flu shots. Because it targets the nose and lungs, it may prevent infection at the earliest stage. Wed, 04 Feb 2026 11:43:43 EST https://www.sciencedaily.com/releases/2026/02/260204114343.htm https://www.sciencedaily.com/releases/2026/01/260115022808.htm A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening cancer vaccines. Scientists have now developed a drug that shuts down this pathway, dramatically boosting immune responses and slowing cancer growth in preclinical studies. Fri, 16 Jan 2026 06:06:55 EST https://www.sciencedaily.com/releases/2026/01/260115022808.htm https://www.sciencedaily.com/releases/2025/12/251228020010.htm A randomized trial from Vanderbilt-Ingram Cancer Center reveals that magnesium may be the missing key to keeping vitamin D levels in balance. The study found that magnesium raised vitamin D in people who were deficient while dialing it down in those with overly high levels—suggesting a powerful regulating effect. This could help explain why vitamin D supplements don’t work the same way for everyone and why past studies linking vitamin D to cancer and heart disease have produced mixed results. Sun, 28 Dec 2025 02:00:10 EST https://www.sciencedaily.com/releases/2025/12/251228020010.htm https://www.sciencedaily.com/releases/2025/12/251226045343.htm Vitamin C doesn’t just belong in skincare products—it works even better when you eat it. Scientists discovered that vitamin C from food travels through the bloodstream into every layer of the skin, boosting collagen and skin renewal. People who ate two vitamin C–packed kiwifruit daily showed thicker, healthier skin. The findings suggest glowing skin really does start from within. Fri, 26 Dec 2025 11:18:28 EST https://www.sciencedaily.com/releases/2025/12/251226045343.htm https://www.sciencedaily.com/releases/2025/12/251219093309.htm In a rare and historic achievement, Children’s Hospital Colorado successfully completed its first dual heart and liver transplant in a pediatric patient. The life-saving surgery was performed on 11-year-old Gracie Greenlaw, whose congenital heart condition eventually led to liver failure. Dozens of specialists worked together for years to prepare for a moment like this, executing a complex, 16-hour operation. Now months later, Gracie is home, in school, and thriving. Fri, 19 Dec 2025 10:35:40 EST https://www.sciencedaily.com/releases/2025/12/251219093309.htm https://www.sciencedaily.com/releases/2025/12/251213032619.htm Forskolin, a plant-derived compound, shows surprising potential against one of the most aggressive forms of leukemia. Researchers discovered that it not only stops cancer cells from growing but also makes them far more vulnerable to chemotherapy by preventing them from pumping out the drugs meant to kill them. Experts say this dual action could help create safer, more powerful AML treatments with fewer harsh side effects. Sun, 14 Dec 2025 09:37:38 EST https://www.sciencedaily.com/releases/2025/12/251213032619.htm https://www.sciencedaily.com/releases/2025/12/251211040438.htm A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest forms of blood cancer, T-cell acute lymphoblastic leukaemia. By precisely rewriting tiny sections of DNA, scientists at UCL and Great Ormond Street Hospital created universal CAR T-cells capable of targeting the cancer without harming themselves—a long-standing challenge in T-cell–based therapies. Early trial results show deep, long-lasting remissions, including in patients who had exhausted standard treatment options. Thu, 11 Dec 2025 04:14:40 EST https://www.sciencedaily.com/releases/2025/12/251211040438.htm https://www.sciencedaily.com/releases/2025/12/251203004721.htm A unique vaccine rollout in Wales gave researchers an accidental natural experiment that revealed a striking reduction in dementia among seniors who received the shingles vaccine. The protective effect held steady across multiple analyses and was even stronger in women. Evidence also suggests benefits for people who already have dementia, hinting at a therapeutic effect. Wed, 03 Dec 2025 10:22:27 EST https://www.sciencedaily.com/releases/2025/12/251203004721.htm https://www.sciencedaily.com/releases/2025/11/251126095018.htm Researchers at Stanford found a way to cure or prevent Type 1 diabetes in mice using a combined blood stem cell and islet cell transplant. The procedure creates a hybrid immune system that stops autoimmune attacks and eliminates the need for immune-suppressing drugs. The method uses tools already common in clinical practice, putting human trials within reach. Scientists think the same strategy could transform treatments for autoimmune conditions and organ transplantation. Wed, 26 Nov 2025 12:05:21 EST https://www.sciencedaily.com/releases/2025/11/251126095018.htm https://www.sciencedaily.com/releases/2025/11/251118220049.htm Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and interferon-responsive T cells create a self-sustaining inflammatory loop that weakens blood production. Surprisingly, the mutant cells themselves may not be the main instigators. Tue, 18 Nov 2025 22:00:49 EST https://www.sciencedaily.com/releases/2025/11/251118220049.htm https://www.sciencedaily.com/releases/2025/11/251110021043.htm Intermountain Health researchers discovered that customizing vitamin D3 doses for heart attack survivors slashed their risk of another heart attack by 50%. The strategy involved frequent monitoring and dose adjustments to reach ideal vitamin D levels. Traditional studies didn’t track blood levels, missing this critical link. Mon, 10 Nov 2025 07:45:02 EST https://www.sciencedaily.com/releases/2025/11/251110021043.htm https://www.sciencedaily.com/releases/2025/11/251107010324.htm A Stanford-led team has replaced toxic pre-transplant chemotherapy with a targeted antibody, allowing children with Fanconi anemia to receive stem cell transplants safely. The antibody, briquilimab, removes diseased stem cells without radiation, enabling nearly complete donor cell replacement. The approach also widens donor eligibility and could soon be applied to other bone marrow failure diseases. Fri, 07 Nov 2025 22:28:44 EST https://www.sciencedaily.com/releases/2025/11/251107010324.htm https://www.sciencedaily.com/releases/2025/11/251105050718.htm A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing power while avoiding side effects. This innovation may usher in a new era of precision nanomedicine for cancer and beyond. Wed, 05 Nov 2025 23:23:15 EST https://www.sciencedaily.com/releases/2025/11/251105050718.htm https://www.sciencedaily.com/releases/2025/10/251027224837.htm Researchers found that COVID-19 mRNA vaccines significantly increased survival in lung and skin cancer patients undergoing immunotherapy. The vaccine appears to prime the immune system in a powerful, nonspecific way, enhancing cancer treatment outcomes. If confirmed, the discovery could lead to a universal cancer vaccine and transform oncology care. Tue, 28 Oct 2025 09:47:26 EDT https://www.sciencedaily.com/releases/2025/10/251027224837.htm https://www.sciencedaily.com/releases/2025/10/251019120503.htm A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t. Researchers from the University of Florida and MD Anderson Cancer Center discovered that the vaccine’s immune-activating properties may boost cancer-fighting responses, acting like a nonspecific “flare” that reawakens the immune system. Sun, 19 Oct 2025 12:43:31 EDT https://www.sciencedaily.com/releases/2025/10/251019120503.htm https://www.sciencedaily.com/releases/2025/10/251014014312.htm Researchers have synthesized enhanced vitamin K analogues that outperform natural vitamin K in promoting neuron growth. The new compounds, which combine vitamin K with retinoic acid, activate the mGluR1 receptor to drive neurogenesis. They also efficiently cross the blood-brain barrier and show stability in vivo. This discovery could pave the way for regenerative treatments for Alzheimer’s and related diseases. Tue, 14 Oct 2025 11:08:36 EDT https://www.sciencedaily.com/releases/2025/10/251014014312.htm https://www.sciencedaily.com/releases/2025/10/251004092911.htm Scientists discovered that vitamin D2 supplements can lower levels of vitamin D3, the form the body uses most effectively. Unlike D2, vitamin D3 enhances the immune system’s first line of defense against infections. This raises questions about which type of supplement should be prioritized. Sat, 04 Oct 2025 09:29:11 EDT https://www.sciencedaily.com/releases/2025/10/251004092911.htm https://www.sciencedaily.com/releases/2025/09/250929054920.htm Scientists discovered that inhibiting the enzyme STK17B forces multiple myeloma cells into iron-driven death and makes therapies more effective. Early mouse studies show strong potential for a new treatment approach. Mon, 29 Sep 2025 22:12:19 EDT https://www.sciencedaily.com/releases/2025/09/250929054920.htm https://www.sciencedaily.com/releases/2025/09/250921091002.htm Scientists have discovered that cancer uses a hidden hormone to switch off the body’s natural defenses, allowing tumors to grow unchecked. By uncovering this secret signal, they found a way to block it and restore the immune system’s ability to fight back. The breakthrough not only hints at powerful new cancer treatments but also suggests the same pathway could someday be used to calm autoimmune diseases. Mon, 22 Sep 2025 07:46:47 EDT https://www.sciencedaily.com/releases/2025/09/250921091002.htm https://www.sciencedaily.com/releases/2025/09/250916221917.htm Rogue DNA rings known as ecDNA may hold the key to cracking glioblastoma’s deadly resilience. Emerging before tumors even form, they could offer scientists a crucial early-warning system and a chance to intervene before the disease becomes untreatable. Wed, 17 Sep 2025 21:33:46 EDT https://www.sciencedaily.com/releases/2025/09/250916221917.htm https://www.sciencedaily.com/releases/2025/08/250818102951.htm A breakthrough mRNA cancer vaccine has shown the ability to supercharge the effects of immunotherapy in mice, sparking hope for a universal “off-the-shelf” treatment that could fight multiple cancers. Unlike traditional vaccines designed to target specific tumor proteins, this approach simply revs up the immune system as if it were fighting a virus. The results were dramatic—when paired with checkpoint inhibitors, tumors shrank, and in some cases, the vaccine alone wiped them out. Tue, 19 Aug 2025 02:22:25 EDT https://www.sciencedaily.com/releases/2025/08/250818102951.htm https://www.sciencedaily.com/releases/2025/06/250609060137.htm A breakthrough study from Keck Medicine of USC may have found a powerful new triple therapy for glioblastoma, one of the deadliest brain cancers. By combining Tumor Treating Fields (TTFields), which deliver electric waves into tumors, with immunotherapy and chemotherapy, researchers saw a major boost in survival. Mon, 09 Jun 2025 06:01:37 EDT https://www.sciencedaily.com/releases/2025/06/250609060137.htm https://www.sciencedaily.com/releases/2025/05/250521124803.htm Researchers have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather than in the embryo, as previously thought. Wed, 21 May 2025 12:48:03 EDT https://www.sciencedaily.com/releases/2025/05/250521124803.htm https://www.sciencedaily.com/releases/2025/05/250521124450.htm An international study has uncovered why a widely used treatment for acute myeloid leukemia (AML) doesn't work for everyone. The findings could help doctors better match patients with the therapies most likely to work for them. Wed, 21 May 2025 12:44:50 EDT https://www.sciencedaily.com/releases/2025/05/250521124450.htm https://www.sciencedaily.com/releases/2025/05/250520224245.htm Scientists and medics have developed an ultra-rapid method of genetically diagnosing brain tumors that will cut the time it takes to classify them from 6-8 weeks, to as little as two hours.The team utilized the new approach during 50 brain tumor surgeries to deliver rapid, intraoperative diagnoses. This approach has achieved a 100% success rate, providing diagnostic results in under two hours from surgery and detailed tumor classifications within minutes of sequencing. Tue, 20 May 2025 22:42:45 EDT https://www.sciencedaily.com/releases/2025/05/250520224245.htm https://www.sciencedaily.com/releases/2025/05/250515145628.htm A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional approaches haven't worked -- largely because HIV mutates rapidly and hides key parts of itself from the immune system. Now, a new study combining data from two separate phase 1 clinical trials shows that a targeted vaccine strategy can successfully activate early immune responses relevant to HIV, and, in one trial, further advance them -- a key step toward a long-sought goal in vaccine development. Thu, 15 May 2025 14:56:28 EDT https://www.sciencedaily.com/releases/2025/05/250515145628.htm https://www.sciencedaily.com/releases/2025/05/250514111056.htm A study shows that leukemia cells drink up taurine, which is produced in the body and also consumed through foods and in energy drinks, and use it as fuel for growth. This highlights a potential to block taurine uptake as a possible treatment. Wed, 14 May 2025 11:10:56 EDT https://www.sciencedaily.com/releases/2025/05/250514111056.htm https://www.sciencedaily.com/releases/2025/04/250428220307.htm A highly sensitive bone marrow test could double survival rates for some groups of younger adults with Acute Myeloid Leukemia (AML) by helping doctors identify if they might relapse up to three months earlier. Mon, 28 Apr 2025 22:03:07 EDT https://www.sciencedaily.com/releases/2025/04/250428220307.htm https://www.sciencedaily.com/releases/2025/04/250423185925.htm Researchers have discovered that expansion of mutant blood cells, a phenomenon linked to aging, can be found in cancerous tumors, and this is associated with worse outcomes for patients. Wed, 23 Apr 2025 18:59:25 EDT https://www.sciencedaily.com/releases/2025/04/250423185925.htm https://www.sciencedaily.com/releases/2025/04/250416135226.htm A new study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 months. Wed, 16 Apr 2025 13:52:26 EDT https://www.sciencedaily.com/releases/2025/04/250416135226.htm https://www.sciencedaily.com/releases/2025/04/250411112928.htm A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team identified a monoclonal antibody called KG2032 that reacts with a certain variant of the HLA-DRB1 molecule. KG2032 CAR T cells displayed strong anti-AML effects in a mouse model, and CAR natural killer cells showed similar results. Clinical trials are currently being planned. Fri, 11 Apr 2025 11:29:28 EDT https://www.sciencedaily.com/releases/2025/04/250411112928.htm https://www.sciencedaily.com/releases/2025/04/250410130742.htm Research has shed light on how a new type of antibody treatment reactivates patients' immune cells to fight ovarian cancer. Thu, 10 Apr 2025 13:07:42 EDT https://www.sciencedaily.com/releases/2025/04/250410130742.htm https://www.sciencedaily.com/releases/2025/04/250409155033.htm Chronic myeloid leukemia may seem to appear suddenly, but new research shows it begins years before diagnosis with an explosive surge of growth. Scientists tracked how a single genetic accident—the fusion of two genes into the notorious BCR::ABL1 "Philadelphia chromosome"—can spark runaway cell multiplication at rates up to 100,000% per year. This growth is so aggressive that it outpaces most other cancers, powered by just one mutation rather than the slow accumulation of many. Wed, 09 Apr 2025 15:50:33 EDT https://www.sciencedaily.com/releases/2025/04/250409155033.htm https://www.sciencedaily.com/releases/2025/04/250402122149.htm A unique vaccination rollout in Wales offered researchers a natural experiment: some older adults qualified for the shingles vaccine, while others just missed the cutoff. The results were striking — those who got the shot had a 20% lower risk of developing dementia within seven years. This breakthrough hints that viruses lurking in the nervous system may contribute to dementia and that prevention could be simpler than anyone imagined. Wed, 02 Apr 2025 12:21:49 EDT https://www.sciencedaily.com/releases/2025/04/250402122149.htm https://www.sciencedaily.com/releases/2025/04/250401131309.htm A team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and analyzing their proteins. The team has combined these two techniques to identify and test a drug for a young patient's tumor in time to be used for their treatment. Their success in finding a new drug for the patient shows how the study of proteins, known as proteomics, can be a valuable complement to the established study of genes (genomics) in real-time cancer therapies. Tue, 01 Apr 2025 13:13:09 EDT https://www.sciencedaily.com/releases/2025/04/250401131309.htm https://www.sciencedaily.com/releases/2025/03/250327141419.htm Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued. This transcript that is unique for CML is more sensitive and accurate than the current standard, real-time quantitative PCR (RT-qPCR), for detecting ultralow levels of residual leukemic disease. Thu, 27 Mar 2025 14:14:19 EDT https://www.sciencedaily.com/releases/2025/03/250327141419.htm https://www.sciencedaily.com/releases/2025/03/250319143643.htm A study has found that a single dose of the Imvanex vaccine provides protection against Mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer sufficient protection. All at-risk groups, and people with HIV in particular, should therefore receive the second dose of the vaccine as recommended. Wed, 19 Mar 2025 14:36:43 EDT https://www.sciencedaily.com/releases/2025/03/250319143643.htm https://www.sciencedaily.com/releases/2025/03/250318141818.htm Small amounts of a common antibiotic and anti-inflammatory drug can curb symptoms where a misplaced immune reaction (e.g., autoimmunity) can cause permanent hair loss, a new study shows. This regimen may also come with fewer side effects than higher doses of the medication. Tue, 18 Mar 2025 14:18:18 EDT https://www.sciencedaily.com/releases/2025/03/250318141818.htm