https://www.sciencedaily.com/news/mind_brain/multiple_sclerosis/ Information on multiple sclerosis. Read current research articles and learn about multiple sclerosis diagnosis, symptoms as well as the latest MS treatment options. en-us Wed, 15 Apr 2026 09:41:47 EDT Wed, 15 Apr 2026 09:41:47 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/mind_brain/multiple_sclerosis/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/04/260414075648.htm A lifetime of mental stimulation—like reading, writing, and learning new skills—may help protect the brain as we age. People with the highest levels of cognitive enrichment had a much lower risk of Alzheimer’s and experienced symptoms years later than those with the lowest levels. Wed, 15 Apr 2026 04:09:05 EDT https://www.sciencedaily.com/releases/2026/04/260414075648.htm https://www.sciencedaily.com/releases/2026/04/260409101111.htm Alzheimer’s isn’t just one problem—it’s a tangled mix of biology, aging, and overall health. That’s why drugs targeting a single factor have fallen short, even as new treatments show modest benefits. Scientists are now pushing toward multi-pronged strategies, from gene editing to brain-cell rejuvenation and gut health interventions. The goal: stop treating Alzheimer’s as one disease and start tackling it as a complex system. Fri, 10 Apr 2026 10:12:15 EDT https://www.sciencedaily.com/releases/2026/04/260409101111.htm https://www.sciencedaily.com/releases/2026/03/260311004720.htm Scientists have developed a promising new approach to treating Alzheimer’s disease by turning ordinary brain cells into powerful plaque-clearing machines. Instead of requiring frequent antibody infusions like current therapies, the experimental treatment uses genetically engineered astrocytes — abundant support cells in the brain — that are equipped with a CAR “homing device” similar to those used in cancer immunotherapy. Wed, 11 Mar 2026 17:01:42 EDT https://www.sciencedaily.com/releases/2026/03/260311004720.htm https://www.sciencedaily.com/releases/2026/02/260215225555.htm Researchers have identified two brain receptors that help the brain clear away amyloid beta, a hallmark of Alzheimer’s disease. By stimulating these receptors in mice, scientists increased levels of a natural amyloid-breaking enzyme, reduced buildup in the brain, and improved memory-related behavior. Because these receptors are common drug targets, the findings could open the door to affordable pill-based treatments with fewer side effects. Tue, 17 Feb 2026 05:30:08 EST https://www.sciencedaily.com/releases/2026/02/260215225555.htm https://www.sciencedaily.com/releases/2026/01/260113220915.htm Despite longstanding guidelines, many dementia patients are still prescribed brain-altering medications that can raise the risk of falls and confusion. A new study shows that while prescribing has decreased overall, people with cognitive impairment remain more likely to receive these drugs. In many cases, there was no documented medical justification. The results suggest that medication safety remains a serious concern in dementia care. Tue, 13 Jan 2026 23:17:46 EST https://www.sciencedaily.com/releases/2026/01/260113220915.htm https://www.sciencedaily.com/releases/2026/01/260112001041.htm Researchers have discovered a brain activity pattern that can predict which people with mild cognitive impairment are likely to develop Alzheimer’s disease. Using a noninvasive brain scanning technique and a custom analysis tool, they detected subtle changes in electrical signals tied to memory processing years before diagnosis. The findings point to a new way of spotting Alzheimer’s early—by listening directly to how neurons behave. Mon, 12 Jan 2026 09:24:19 EST https://www.sciencedaily.com/releases/2026/01/260112001041.htm https://www.sciencedaily.com/releases/2025/12/251228020016.htm Researchers discovered that clogged brain “drains” show up early in people at risk of Alzheimer’s disease. These blockages, easily seen on standard MRI scans, are tied to toxic protein buildup linked to memory loss and cognitive decline. In some cases, they may signal Alzheimer’s earlier than other commonly used brain markers. This could help physicians detect the disease earlier, before irreversible damage sets in. Sat, 03 Jan 2026 00:45:11 EST https://www.sciencedaily.com/releases/2025/12/251228020016.htm https://www.sciencedaily.com/releases/2025/12/251222080119.htm New research suggests Alzheimer’s may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early damage in mice and reduces inflammation linked to disease progression. The treatment was given before symptoms appeared, targeting the disease at its earliest stage. Researchers say this approach could reshape how Alzheimer’s is prevented and treated. Mon, 22 Dec 2025 08:11:02 EST https://www.sciencedaily.com/releases/2025/12/251222080119.htm https://www.sciencedaily.com/releases/2025/12/251218060615.htm Spending a few hours a week helping others may slow the aging of the brain. Researchers found that both formal volunteering and informal acts, like helping neighbors or relatives, were linked to noticeably slower cognitive decline over time. The benefits added up year after year and didn’t require a huge time commitment. Even modest, everyday helping packed a powerful mental payoff. Fri, 19 Dec 2025 10:08:36 EST https://www.sciencedaily.com/releases/2025/12/251218060615.htm https://www.sciencedaily.com/releases/2025/11/251127010319.htm Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment. The group showed higher inflammation, signs of liver strain and elevated neurofilament light chain, a marker of neuron injury. Low choline levels appeared closely tied to these changes. The results hint that early metabolic disruptions may quietly influence the brain long before symptoms emerge. Thu, 27 Nov 2025 02:45:12 EST https://www.sciencedaily.com/releases/2025/11/251127010319.htm https://www.sciencedaily.com/releases/2025/11/251123115708.htm Hypertension begins harming the brain surprisingly early, even before measurable blood pressure increases. Key cells related to blood vessels, signaling, and myelin maintenance begin aging prematurely and malfunctioning. These disruptions resemble early patterns seen in cognitive decline and Alzheimer’s. Encouragingly, losartan reversed some of this early damage in mice. Mon, 24 Nov 2025 09:33:36 EST https://www.sciencedaily.com/releases/2025/11/251123115708.htm https://www.sciencedaily.com/releases/2025/11/251121090731.htm Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered plaque levels, reduced inflammation, and improved behavior. Its strong safety record and low cost make it a promising repurposing candidate. The findings hint at a surprisingly simple path toward more accessible AD therapies. Fri, 21 Nov 2025 11:33:04 EST https://www.sciencedaily.com/releases/2025/11/251121090731.htm https://www.sciencedaily.com/releases/2025/11/251118220052.htm Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The treatment restored memory and reduced inflammation in rats, while also proving non-toxic and able to cross the blood–brain barrier. Because it’s far simpler and potentially cheaper than existing drugs, researchers are now pursuing partnerships to begin human trials. Wed, 19 Nov 2025 10:46:50 EST https://www.sciencedaily.com/releases/2025/11/251118220052.htm https://www.sciencedaily.com/releases/2025/11/251116105633.htm Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable tool for supporting cognitive resilience in aging. Mon, 17 Nov 2025 09:31:10 EST https://www.sciencedaily.com/releases/2025/11/251116105633.htm https://www.sciencedaily.com/releases/2025/11/251111005944.htm Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to reverse. Their findings underscore that tackling amyloid alone may not be enough to restore brain function, urging a broader approach to treatment. Tue, 11 Nov 2025 01:47:33 EST https://www.sciencedaily.com/releases/2025/11/251111005944.htm https://www.sciencedaily.com/releases/2025/11/251104013008.htm Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of harmful tau proteins in the brain. The researchers say these results show lifestyle changes can meaningfully delay Alzheimer’s symptoms, especially in early stages. Tue, 04 Nov 2025 09:16:57 EST https://www.sciencedaily.com/releases/2025/11/251104013008.htm https://www.sciencedaily.com/releases/2025/10/251029100154.htm Researchers used supramolecular nanoparticles to repair the brain’s vascular system and reverse Alzheimer’s in mice. Instead of carrying drugs, the nanoparticles themselves triggered natural clearance of amyloid-β proteins. This restored blood-brain barrier function and reversed memory loss. The results point to a revolutionary new path for treating neurodegenerative diseases. Wed, 29 Oct 2025 10:01:54 EDT https://www.sciencedaily.com/releases/2025/10/251029100154.htm https://www.sciencedaily.com/releases/2025/10/251022023113.htm Scientists have uncovered a toxic alliance between Aβ and fibrinogen that may explain how Alzheimer’s disease begins. The two proteins together create stubborn clots that damage blood vessels and spark inflammation in the brain. These effects appear even at very low concentrations and disrupt the blood-brain barrier, paving the way for neurodegeneration. The findings highlight a potential new therapeutic target for early intervention. Wed, 22 Oct 2025 09:19:26 EDT https://www.sciencedaily.com/releases/2025/10/251022023113.htm https://www.sciencedaily.com/releases/2025/09/250924012257.htm For decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue researchers have revealed a hidden culprit: fat. They found that brain immune cells can become clogged with fat, leaving them too weak to fight off disease. By clearing out this fat and restoring the cells’ defenses, researchers may have uncovered an entirely new way to combat Alzheimer’s — shifting the focus from plaques alone to how the brain handles fat. Wed, 24 Sep 2025 23:56:50 EDT https://www.sciencedaily.com/releases/2025/09/250924012257.htm https://www.sciencedaily.com/releases/2025/09/250920214459.htm New studies reveal that lifestyle changes—such as exercise, healthy eating, and social engagement—can help slow or prevent cognitive decline. Experts say this low-cost, powerful approach could transform dementia care and reduce its crushing toll on families and health systems. Sun, 21 Sep 2025 09:42:01 EDT https://www.sciencedaily.com/releases/2025/09/250920214459.htm https://www.sciencedaily.com/releases/2025/09/250913232924.htm Chronic insomnia may do more than leave you groggy, it could speed up brain aging. A large Mayo Clinic study found that people with long-term sleep troubles were 40% more likely to develop dementia or cognitive impairment, with brain scans showing changes linked to Alzheimer’s. Those reporting reduced sleep showed declines comparable to being four years older, while certain genetic risk carriers saw even steeper drops. Sun, 14 Sep 2025 02:02:57 EDT https://www.sciencedaily.com/releases/2025/09/250913232924.htm https://www.sciencedaily.com/releases/2025/09/250909031511.htm Scientists discovered that certain blood proteins linked to brain injury and inflammation strongly correlate with early signs of memory and cognitive decline, especially in Hispanic and Latino adults. This breakthrough points to a future where Alzheimer’s could be detected early with a simple blood test. Tue, 09 Sep 2025 22:05:55 EDT https://www.sciencedaily.com/releases/2025/09/250909031511.htm https://www.sciencedaily.com/releases/2025/08/250829022829.htm Harvard scientists have uncovered that lithium, a naturally occurring element in the brain, may be the missing piece in understanding Alzheimer’s. Their decade-long research shows that lithium depletion—caused by amyloid plaques binding to it—triggers early brain changes that lead to memory loss. By testing new lithium compounds that evade plaque capture, they reversed Alzheimer’s-like damage and restored memory in mice at doses far lower than those used in psychiatric treatments. Fri, 29 Aug 2025 02:57:32 EDT https://www.sciencedaily.com/releases/2025/08/250829022829.htm https://www.sciencedaily.com/releases/2025/08/250822073817.htm St. Jude researchers revealed that midkine blocks amyloid beta from forming harmful clumps linked to Alzheimer’s. Without it, the damaging assemblies accelerate, but with it, growth halts. The finding could inspire new drugs that harness midkine’s protective power. Sat, 23 Aug 2025 10:21:32 EDT https://www.sciencedaily.com/releases/2025/08/250822073817.htm https://www.sciencedaily.com/releases/2025/07/250717013905.htm A massive European study has uncovered a powerful connection between hearing loss, loneliness, and memory decline. Researchers at the University of Geneva found that older adults with hearing impairments who also feel lonely—regardless of actual social isolation—experience faster cognitive decline. Fri, 18 Jul 2025 00:20:12 EDT https://www.sciencedaily.com/releases/2025/07/250717013905.htm https://www.sciencedaily.com/releases/2025/07/250706230311.htm When you're mentally exhausted, your brain might be doing more behind the scenes than you think. In a new study using functional MRI, researchers uncovered two key brain regions that activate when people feel cognitively fatigued—regions that appear to weigh the cost of continuing mental effort versus giving up. Surprisingly, participants needed high financial incentives to push through challenging memory tasks, hinting that motivation can override mental fatigue. These insights may pave the way to treating brain fog in disorders like PTSD and depression using brain imaging and behavior-based therapies. Mon, 07 Jul 2025 04:34:10 EDT https://www.sciencedaily.com/releases/2025/07/250706230311.htm https://www.sciencedaily.com/releases/2025/06/250629033408.htm USC researchers have found a promising new brain scan marker that could better detect Alzheimer’s risk — but only for some. The tau-based benchmark works in Hispanic and White populations when paired with another Alzheimer’s protein, amyloid, but falls short for Black participants, revealing critical gaps in current diagnostics. Sun, 29 Jun 2025 04:13:30 EDT https://www.sciencedaily.com/releases/2025/06/250629033408.htm https://www.sciencedaily.com/releases/2025/06/250622224303.htm A simple blood test could reveal which early Alzheimer’s patients are most at risk for rapid decline. Researchers found that people with high insulin resistance—measured by the TyG index—were four times more likely to experience faster cognitive deterioration. The study highlights a major opportunity: a common lab value already available in hospitals could help guide personalized treatment strategies. This discovery also uncovers a unique vulnerability in Alzheimer’s disease to metabolic stress, offering new possibilities for intervention while the disease is still in its early stages. Sun, 22 Jun 2025 22:43:03 EDT https://www.sciencedaily.com/releases/2025/06/250622224303.htm https://www.sciencedaily.com/releases/2025/05/250516133225.htm While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, researchers provide a new understanding of how Alzheimer's disease affects different tissues across the entire body. The findings reveal new insights into brain-body communication in neurodegeneration and pave the way for identifying novel biomarkers and therapeutic targets for Alzheimer's disease. Fri, 16 May 2025 13:32:25 EDT https://www.sciencedaily.com/releases/2025/05/250516133225.htm https://www.sciencedaily.com/releases/2025/05/250512133656.htm Cancer treatment with a cell-based immunotherapy causes mild cognitive impairment, a Stanford Medicine team found. They also identified compounds that could treat it. Mon, 12 May 2025 13:36:56 EDT https://www.sciencedaily.com/releases/2025/05/250512133656.htm https://www.sciencedaily.com/releases/2025/04/250424120851.htm In a landmark clinical trial people at risk for Alzheimer's who exercised at low or moderate-high intensity showed less cognitive decline when compared to those receiving usual care. Thu, 24 Apr 2025 12:08:51 EDT https://www.sciencedaily.com/releases/2025/04/250424120851.htm https://www.sciencedaily.com/releases/2025/04/250423112628.htm People with Alzheimer's disease may retain their ability to empathize, despite declines in other social abilities, finds a new study. Wed, 23 Apr 2025 11:26:28 EDT https://www.sciencedaily.com/releases/2025/04/250423112628.htm https://www.sciencedaily.com/releases/2025/04/250421162929.htm A new study suggests that risk factors and biomarkers related to Alzheimer's disease are associated with cognition much earlier in life than previously recognized. The study highlights significant associations between cognition and Alzheimer's disease risk factors as young as ages 24 to 44 and underscores the importance of early prevention. This is the first study to systematically examine Alzheimer's disease risk factors, including biomarkers related to cognitive impairment in a large group of generally healthy middle-aged individuals in the U.S. Mon, 21 Apr 2025 16:29:29 EDT https://www.sciencedaily.com/releases/2025/04/250421162929.htm https://www.sciencedaily.com/releases/2025/04/250417145247.htm Among adults ages 18-49 (median age of 41 years) who were born with a hole in the upper chambers of their heart known as patent foramen ovale (PFO), strokes of unknown cause were more strongly associated with nontraditional risk factors, such as migraines, liver disease or cancer, rather than more typical factors such as high blood pressure. Thu, 17 Apr 2025 14:52:47 EDT https://www.sciencedaily.com/releases/2025/04/250417145247.htm https://www.sciencedaily.com/releases/2025/04/250416135456.htm Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms. This is evident in the levels of the protein 'beta-synuclein'. Wed, 16 Apr 2025 13:54:56 EDT https://www.sciencedaily.com/releases/2025/04/250416135456.htm https://www.sciencedaily.com/releases/2025/04/250408121324.htm Experimental drug NU-9 -- a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) -- improves neuron health in animal models of Alzheimer's disease, according to a new study. Tue, 08 Apr 2025 12:13:24 EDT https://www.sciencedaily.com/releases/2025/04/250408121324.htm https://www.sciencedaily.com/releases/2025/04/250403122639.htm There are over six million Americans with heart failure who are at greater risk of losing their cognitive abilities earlier in life, a study suggests. Global cognition and executive functioning declined more rapidly over the years after heart failure diagnosis, as people with the condition mentally aged the equivalent of 10 years within just seven years of a heart failure diagnosis. Thu, 03 Apr 2025 12:26:39 EDT https://www.sciencedaily.com/releases/2025/04/250403122639.htm https://www.sciencedaily.com/releases/2025/03/250331122226.htm A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a new study. Mon, 31 Mar 2025 12:22:26 EDT https://www.sciencedaily.com/releases/2025/03/250331122226.htm https://www.sciencedaily.com/releases/2025/03/250326122658.htm Stroke survivors who have attended some level of higher education may face even steeper mental declines, according to a study. The findings suggest that attending higher education may enable people to retain greater cognitive ability until a critical threshold of brain injury is reached after a stroke. Wed, 26 Mar 2025 12:26:58 EDT https://www.sciencedaily.com/releases/2025/03/250326122658.htm https://www.sciencedaily.com/releases/2025/03/250324141955.htm Researchers developed olfactory tests -- in which participants sniff odor labels that have been placed on a card -- to assess people's ability to discriminate, identify and remember odors. They found that participants could successfully take the test at home and that older adults with cognitive impairment scored lower on the test than cognitively normal adults. Mon, 24 Mar 2025 14:19:55 EDT https://www.sciencedaily.com/releases/2025/03/250324141955.htm https://www.sciencedaily.com/releases/2025/03/250306122929.htm A new study suggests a promising alternative to previous attempts to remove the sticky, toxic amyloid beta plaques from brains with Alzheimer's Disease: enhancing the brain's own immune cells to clear these plaques more effectively. The findings could reshape the future of Alzheimer's treatments, shifting the focus from simply removing plaques to harnessing the brain's natural defenses. Thu, 06 Mar 2025 12:29:29 EST https://www.sciencedaily.com/releases/2025/03/250306122929.htm https://www.sciencedaily.com/releases/2025/03/250304113808.htm Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity - a harmful condition linked to the progression of type 2 diabetes (T2D). These findings could lead to promising treatments targeting beta cell dysfunction. Tue, 04 Mar 2025 11:38:08 EST https://www.sciencedaily.com/releases/2025/03/250304113808.htm https://www.sciencedaily.com/releases/2025/02/250226142618.htm Researchers published a study analyzing more than 30 years of aging and dementia patterns of 678 nuns. Wed, 26 Feb 2025 14:26:18 EST https://www.sciencedaily.com/releases/2025/02/250226142618.htm https://www.sciencedaily.com/releases/2025/02/250224155058.htm A new artificial intelligence model measures how fast a patient's brain is aging and could be a powerful new tool for understanding, preventing and treating cognitive decline and dementia. Mon, 24 Feb 2025 15:50:58 EST https://www.sciencedaily.com/releases/2025/02/250224155058.htm https://www.sciencedaily.com/releases/2025/02/250218203749.htm Meeting the minimum requirement for vitamin B12, needed to make DNA, red blood cells and nerve tissue, may not actually be enough -- particularly if you are older. It may even put you at risk for cognitive impairment. Tue, 18 Feb 2025 20:37:49 EST https://www.sciencedaily.com/releases/2025/02/250218203749.htm https://www.sciencedaily.com/releases/2025/02/250210132601.htm Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms that litter the brain, cerebrospinal fluid and potentially blood, new research suggests. Mon, 10 Feb 2025 13:26:01 EST https://www.sciencedaily.com/releases/2025/02/250210132601.htm https://www.sciencedaily.com/releases/2025/02/250206113504.htm A research team has discovered that the two key pathological hallmarks of Alzheimer's -- tau protein and beta-amyloid -- affect brain circuits in distinct yet synergistic ways, particularly those linked to memory and emotions. The study, using a new animal model of Alzheimer's disease, suggests a potential breakthrough in treatment strategies. Current therapies mainly focus on blocking just one of the toxic proteins associated with the disease, but this discovery could pave the way for more comprehensive approaches. Thu, 06 Feb 2025 11:35:04 EST https://www.sciencedaily.com/releases/2025/02/250206113504.htm https://www.sciencedaily.com/releases/2025/02/250205131556.htm A new study has found that certain bacteria were associated with better memory and attention, while others were linked to an increased risk of Alzheimer's disease. Wed, 05 Feb 2025 13:15:56 EST https://www.sciencedaily.com/releases/2025/02/250205131556.htm https://www.sciencedaily.com/releases/2025/02/250204141840.htm A paradigm-shifting study shows an experimental drug, GL-II-73, has the potential to restore memory and cognitive function in a mouse model of Alzheimer's disease. The study demonstrates that the drug improves memory deficits and reverses brain cell damage, offering hope for improving cognitive functioning, delaying Alzheimer's progression, and potentially preventing some of the brain damages associated with the disease. Tue, 04 Feb 2025 14:18:40 EST https://www.sciencedaily.com/releases/2025/02/250204141840.htm https://www.sciencedaily.com/releases/2025/01/250130172819.htm Being more social by visiting friends, attending parties and going to church may help keep your brain healthy, according to new research. Thu, 30 Jan 2025 17:28:19 EST https://www.sciencedaily.com/releases/2025/01/250130172819.htm https://www.sciencedaily.com/releases/2025/01/250130161709.htm An artificial intelligence (AI) model designed to predict a person's biological age (age of body cells and tissues) based on electrocardiogram (ECG) data found a strong association between ECG-age and cognitive performance. Thu, 30 Jan 2025 16:17:09 EST https://www.sciencedaily.com/releases/2025/01/250130161709.htm https://www.sciencedaily.com/releases/2025/01/250129162139.htm Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a new study. Wed, 29 Jan 2025 16:21:39 EST https://www.sciencedaily.com/releases/2025/01/250129162139.htm https://www.sciencedaily.com/releases/2025/01/250128123926.htm Schizophrenia is a serious mental disorder that affects around 1% of the world's population. Researchers have identified a deficit in contrast perception in people with schizophrenia. According to a review of more than 600 studies, these patients have an impaired ability to see differences in light intensity between adjacent areas, which allows us to identify shapes, textures and details in the environment. Tue, 28 Jan 2025 12:39:26 EST https://www.sciencedaily.com/releases/2025/01/250128123926.htm https://www.sciencedaily.com/releases/2025/01/250122145814.htm New guidelines will help doctors identify patients with a common memory-loss syndrome that is often misdiagnosed as Alzheimer's disease in older adults. The diagnostic criteria for limbic-predominant age-related TDP-43 encephalopathy (LATE) have just been published. These guidelines are an important first step in advancing clinical trials and treatments for this lesser-known, but common type of memory loss disorder. Wed, 22 Jan 2025 14:58:14 EST https://www.sciencedaily.com/releases/2025/01/250122145814.htm https://www.sciencedaily.com/releases/2025/01/250117123453.htm A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual (left) shows a larger brain with more white matter compared with a brain image from a patient with sickle cell disease (right). Healthy individuals experiencing economic deprivation also had more-aged appearing brains. Fri, 17 Jan 2025 12:34:53 EST https://www.sciencedaily.com/releases/2025/01/250117123453.htm https://www.sciencedaily.com/releases/2025/01/250115164828.htm People who eat more red meat, especially processed red meat like bacon, sausage and bologna, are more likely to have a higher risk of cognitive decline and dementia when compared to those who eat very little red meat, according to a new study. Wed, 15 Jan 2025 16:48:28 EST https://www.sciencedaily.com/releases/2025/01/250115164828.htm https://www.sciencedaily.com/releases/2025/01/250115125055.htm An international study has identified three psychological profiles associated with different patterns of cognitive and brain decline in aging. The study, which analyzed more than 1,000 middle-aged and older adults, shows that the specific psychological characteristics of each profile may influence the risk of developing dementia, as well as aspects such as the speed of brain decline and sleep quality. These findings open new perspectives for the design of more personalized prevention strategies. Wed, 15 Jan 2025 12:50:55 EST https://www.sciencedaily.com/releases/2025/01/250115125055.htm https://www.sciencedaily.com/releases/2025/01/250114125250.htm There may be a link between hearing impairment and an increased risk of developing Parkinson's according to new research. This is one of the first studies to examine whether sensory impairments, such as hearing loss, might increase the risk for Parkinson's or serve as an early warning sign. Parkinson's UK reports that an estimated 153,000 people in the UK currently live with Parkinson's, which is the fastest-growing neurological condition in the world. Tue, 14 Jan 2025 12:52:50 EST https://www.sciencedaily.com/releases/2025/01/250114125250.htm https://www.sciencedaily.com/releases/2025/01/250108144144.htm Declining blood levels of two molecules that occur naturally in the body track closely with worsening Alzheimer's disease, particularly in women. Levels were found to drop gradually, from women with no signs of memory, disorientation, and slowed thinking to those with early signs of mild cognitive impairment. Decreases were more prominent in women with moderate or severe stages of the disease. Declines in men were evident in only one molecule, revealing a disease-specific difference between the men and women. Wed, 08 Jan 2025 14:41:44 EST https://www.sciencedaily.com/releases/2025/01/250108144144.htm https://www.sciencedaily.com/releases/2024/12/241219151726.htm A study of more than 2,400 people with atrial fibrillation, who had an average age of 73, found that drinking more than five cups of caffeinated coffee daily was associated with better performance on an array of cognitive tests than drinking less than one cup or avoiding coffee altogether. Thu, 19 Dec 2024 15:17:26 EST https://www.sciencedaily.com/releases/2024/12/241219151726.htm