https://www.sciencedaily.com/news/mind_brain/opium/ Read medical research on the effect of opium and related controlled substances such as morphine, codeine, heroin, percocet and methadone on the body. en-us Wed, 22 Apr 2026 05:36:34 EDT Wed, 22 Apr 2026 05:36:34 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/mind_brain/opium/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/03/260328043558.htm Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off switch” that mimics morphine’s benefits but skips its dangerous side effects. In early tests, it delivered lasting relief without affecting normal sensations. The discovery could mark a major step toward safer, non-addictive pain treatments. Sat, 28 Mar 2026 20:57:04 EDT https://www.sciencedaily.com/releases/2026/03/260328043558.htm https://www.sciencedaily.com/releases/2026/03/260305223211.htm Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain. Researchers at Michigan State University discovered that repeated cocaine use rewires communication between the brain’s reward system and the hippocampus, the region responsible for memory. A protein called DeltaFosB builds up with continued drug use and acts like a genetic switch, altering how neurons function and strengthening the brain’s drive to seek cocaine. Fri, 06 Mar 2026 14:45:26 EST https://www.sciencedaily.com/releases/2026/03/260305223211.htm https://www.sciencedaily.com/releases/2025/10/251026021746.htm GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, and nicotine use. Though more research is needed, scientists believe these drugs could open a powerful new front in addiction therapy. Sun, 26 Oct 2025 13:14:29 EDT https://www.sciencedaily.com/releases/2025/10/251026021746.htm https://www.sciencedaily.com/releases/2025/10/251006051124.htm Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the thalamus (PVT) becomes hyperactive when animals learn that alcohol eases the agony of withdrawal. This circuit helps explain why people relapse: their brains learn that alcohol brings relief from stress and anxiety. Mon, 06 Oct 2025 05:11:24 EDT https://www.sciencedaily.com/releases/2025/10/251006051124.htm https://www.sciencedaily.com/releases/2025/09/250929054915.htm Researchers found that middle-aged adults, especially women, are far more likely to be addicted to ultra-processed foods than older generations. Marketing of diet-focused processed foods in the 1980s may have played a major role. Food addiction was linked to poor health, weight issues, and social isolation, highlighting long-term risks. Experts warn that children today could face even higher addiction rates in the future. Mon, 29 Sep 2025 09:57:42 EDT https://www.sciencedaily.com/releases/2025/09/250929054915.htm https://www.sciencedaily.com/releases/2025/09/250901104649.htm Japanese scientists have developed ADRIANA, a non-opioid painkiller that could provide powerful relief without the dangers of addiction. With successful trials already completed, large U.S. studies are now underway, raising hopes for a safer future in pain treatment. Tue, 02 Sep 2025 03:32:58 EDT https://www.sciencedaily.com/releases/2025/09/250901104649.htm https://www.sciencedaily.com/releases/2025/05/250519131126.htm A breakthrough drug from Duke University, SBI-810, promises strong pain relief without the pitfalls of opioids. Unlike traditional painkillers that trigger multiple brain pathways—and often addiction—SBI-810 activates just one specific pathway tied to pain relief, sidestepping the euphoric high, constipation, and tolerance buildup common with opioids. It worked impressively in mice, reducing pain from surgery, fractures, and nerve damage—sometimes outperforming even hospital-grade opioids and gabapentin. Even better, it made opioids more effective at lower doses when used together. Mon, 19 May 2025 13:11:26 EDT https://www.sciencedaily.com/releases/2025/05/250519131126.htm https://www.sciencedaily.com/releases/2025/04/250430142024.htm Researchers found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain's response to natural healthy pleasure, leading to reduced opioid cravings. The findings suggest that MORE could be a promising tool in the fight against opioid use disorder. Wed, 30 Apr 2025 14:20:24 EDT https://www.sciencedaily.com/releases/2025/04/250430142024.htm https://www.sciencedaily.com/releases/2025/04/250430141634.htm Researchers have applied object recognition technology to track changes in brain cell structure and provide new insights into how the brain responds to heroin use, withdrawal and relapse. Wed, 30 Apr 2025 14:16:34 EDT https://www.sciencedaily.com/releases/2025/04/250430141634.htm https://www.sciencedaily.com/releases/2025/04/250428222335.htm Scientists have developed a highly sensitive method to detect illegal opioids and a veterinary sedative in Australia's wastewater system, providing a vital early warning tool to public health authorities. Mon, 28 Apr 2025 22:23:35 EDT https://www.sciencedaily.com/releases/2025/04/250428222335.htm https://www.sciencedaily.com/releases/2025/04/250428220258.htm Ketamine addiction is linked to high levels of physical health problems and psychological consequences, with nearly half of those affected not seeking support or treatment, new research has revealed. Mon, 28 Apr 2025 22:02:58 EDT https://www.sciencedaily.com/releases/2025/04/250428220258.htm https://www.sciencedaily.com/releases/2025/04/250416135606.htm A new imaging study showed that listening to favorite music affects the function of the brain's opioid system. Wed, 16 Apr 2025 13:56:06 EDT https://www.sciencedaily.com/releases/2025/04/250416135606.htm https://www.sciencedaily.com/releases/2025/04/250410130617.htm The heart of the opioid epidemic that killed 665,341 people in the United States between 2005 and 2020 shifted geographically from the Northwest to the East, according to a new geographical analysis. Thu, 10 Apr 2025 13:06:17 EDT https://www.sciencedaily.com/releases/2025/04/250410130617.htm https://www.sciencedaily.com/releases/2025/04/250408191656.htm Scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional pain medications. Tue, 08 Apr 2025 19:16:56 EDT https://www.sciencedaily.com/releases/2025/04/250408191656.htm https://www.sciencedaily.com/releases/2025/04/250407173105.htm Eight weeks of mindfulness or cognitive behavioral therapy were associated with improved pain, physical function and quality of life and reduced daily opioid dose in adults with chronic low back pain that required treated with daily opioids, according to a new study. This is one of the largest studies to date to evaluate mindfulness and cognitive behavioral therapy as treatment for opioid-treated chronic pain. Mon, 07 Apr 2025 17:31:05 EDT https://www.sciencedaily.com/releases/2025/04/250407173105.htm https://www.sciencedaily.com/releases/2025/03/250326122927.htm Researchers have found a unique molecular signature and genes in the orbitofrontal cortex associated with heroin-seeking behavior. A preclinical rodent model implicated a gene called Shisa7 as the key predictor. A new study provides valuable insights into the neurobiological mechanisms underlying heroin addiction and may have implications for the development of innovative strategies to combat the ongoing opioid epidemic. Wed, 26 Mar 2025 12:29:27 EDT https://www.sciencedaily.com/releases/2025/03/250326122927.htm https://www.sciencedaily.com/releases/2025/02/250221125541.htm The combination of prescribed central nervous system stimulants, such as drugs that relieve ADHD symptoms, with prescribed opioid medications is associated with a pattern of escalating opioid intake, a new study has found. Fri, 21 Feb 2025 12:55:41 EST https://www.sciencedaily.com/releases/2025/02/250221125541.htm https://www.sciencedaily.com/releases/2025/02/250220122518.htm With the goal of informing clinician practice, a new study explores the harms and benefits of continuing and of discontinuing the long-term prescription of opioid medicines to adults with chronic pain. Thu, 20 Feb 2025 12:25:18 EST https://www.sciencedaily.com/releases/2025/02/250220122518.htm https://www.sciencedaily.com/releases/2025/02/250219111405.htm In the face of the alarming number of opioid-related deaths in the U.S., there have been national efforts to increase emergency clinician prescribing of buprenorphine, a medication used to treat opioid use disorder. Wed, 19 Feb 2025 11:14:05 EST https://www.sciencedaily.com/releases/2025/02/250219111405.htm https://www.sciencedaily.com/releases/2025/02/250213143309.htm Who hasn't been there? The big meal is over, you're full, but the craving for sweets remains. Researchers have now discovered that what we call the 'dessert stomach' is rooted in the brain. The same nerve cells that make us feel full after a meal are also responsible for our craving for sweets afterwards. Thu, 13 Feb 2025 14:33:09 EST https://www.sciencedaily.com/releases/2025/02/250213143309.htm https://www.sciencedaily.com/releases/2025/01/250113134146.htm A new study found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. However, the findings also show decreases in opioid outcomes after medical marijuana laws existed among people reporting cannabis use. Mon, 13 Jan 2025 13:41:46 EST https://www.sciencedaily.com/releases/2025/01/250113134146.htm https://www.sciencedaily.com/releases/2025/01/250106132328.htm Researchers find an over-the-counter combo is more effective for wisdom tooth extraction pain. Mon, 06 Jan 2025 13:23:28 EST https://www.sciencedaily.com/releases/2025/01/250106132328.htm https://www.sciencedaily.com/releases/2024/12/241211125052.htm Researchers have made a discovery regarding the TRPV1 (transient receptor potential vanilloid 1) ion channel and its role in pain perception. The study reveals how solvent molecules can modulate pain signals, offering a potential pathway for a safer, non-addictive pain management approach. Wed, 11 Dec 2024 12:50:52 EST https://www.sciencedaily.com/releases/2024/12/241211125052.htm https://www.sciencedaily.com/releases/2024/12/241209203738.htm Researchers found that adolescents with more symptoms of gaming addiction showed lower brain activity in the region involved in decision-making and reward processing; this blunted response to reward anticipation is associated with higher symptoms of gaming addiction over time and suggests that reduced sensitivity to rewards, in particular non-gaming rewards, may play a role in problematic gaming. Mon, 09 Dec 2024 20:37:38 EST https://www.sciencedaily.com/releases/2024/12/241209203738.htm https://www.sciencedaily.com/releases/2024/12/241202123655.htm Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ability to relieve pain, according to a new study. Endocannabinoids bind to cannabinoid receptors throughout the body that regulate activities, such as learning and memory, emotions, sleep, immune response and appetite. Mon, 02 Dec 2024 12:36:55 EST https://www.sciencedaily.com/releases/2024/12/241202123655.htm https://www.sciencedaily.com/releases/2024/11/241125145754.htm Research shows that reward-based learning requires the two neuromodulators to balance one another's influence -- like the accelerator and brakes on a car Mon, 25 Nov 2024 14:57:54 EST https://www.sciencedaily.com/releases/2024/11/241125145754.htm https://www.sciencedaily.com/releases/2024/11/241118170700.htm Neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in as little as a few hours with effects lasting for several days. Mon, 18 Nov 2024 17:07:00 EST https://www.sciencedaily.com/releases/2024/11/241118170700.htm https://www.sciencedaily.com/releases/2024/11/241114161513.htm Evidence has been growing to suggest that tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, poses risks to the developing fetus by impacting brain development. Now a new preclinical research study finds that this could increase the risk of addiction to opioids later in life. Thu, 14 Nov 2024 16:15:13 EST https://www.sciencedaily.com/releases/2024/11/241114161513.htm https://www.sciencedaily.com/releases/2024/10/241021133251.htm People with opioid use disorder in British Columbia who received methadone had a 37- to 40-percent lower rate of treatment discontinuation compared with those who received buprenorphine/naloxone. The new research evaluated the risk of treatment discontinuation and mortality in people prescribed opioid agonist treatment (OAT) over a 10-year period. Mon, 21 Oct 2024 13:32:51 EDT https://www.sciencedaily.com/releases/2024/10/241021133251.htm https://www.sciencedaily.com/releases/2024/10/241016120023.htm According to new research, men and women rely on different biological systems for pain relief, which could help explain why our most powerful pain medications are often less effective in women. Wed, 16 Oct 2024 12:00:23 EDT https://www.sciencedaily.com/releases/2024/10/241016120023.htm https://www.sciencedaily.com/releases/2024/10/241009122519.htm Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression. Their illegal use contributes to nearly half a million deaths worldwide each year. Researchers have discovered a molecule, called nanobody NbE, which binds tightly and durably to the cell receptors that usually bind to opioids, thereby blocking the drugs' activity. Moreover, the scientists were able to create even smaller molecules that retain the same properties, which could prove far more effective than current treatments in mitigating the harmful effects of opioids. Wed, 09 Oct 2024 12:25:19 EDT https://www.sciencedaily.com/releases/2024/10/241009122519.htm https://www.sciencedaily.com/releases/2024/09/240925121732.htm Adults with opioid use disorder who receive a higher daily dose of the opioid addiction treatment medication buprenorphine may have a lower risk of subsequent emergency department visits or use of inpatient services related to behavioral health (such as for mental health and substance use disorders) than adults receiving the recommended dose, according to a new analysis. Wed, 25 Sep 2024 12:17:32 EDT https://www.sciencedaily.com/releases/2024/09/240925121732.htm https://www.sciencedaily.com/releases/2024/09/240924165714.htm New findings argue against a direct causal role for dopamine during the experience of a treatment effect in the establishment of positive treatment expectations and placebo analgesia in healthy volunteers, according to a new study. Tue, 24 Sep 2024 16:57:14 EDT https://www.sciencedaily.com/releases/2024/09/240924165714.htm https://www.sciencedaily.com/releases/2024/09/240919120804.htm Drug overdose mortality has risen faster among adolescents than the general population in recent years, largely due to fentanyl, a potent opioid pain medication. A new study sheds light on trends in nonfatal opioid overdoses in youth -- an area that was not as well characterized, but key to formulating prevention strategies to save lives. Thu, 19 Sep 2024 12:08:04 EDT https://www.sciencedaily.com/releases/2024/09/240919120804.htm https://www.sciencedaily.com/releases/2024/09/240917162334.htm A pilot study showed that a small amount of ketamine can reduce or eliminate the withdrawal symptoms associated with quitting fentanyl. Tue, 17 Sep 2024 16:23:34 EDT https://www.sciencedaily.com/releases/2024/09/240917162334.htm https://www.sciencedaily.com/releases/2024/08/240829140754.htm Researchers describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side effects. Thu, 29 Aug 2024 14:07:54 EDT https://www.sciencedaily.com/releases/2024/08/240829140754.htm https://www.sciencedaily.com/releases/2024/08/240816173914.htm A new study that details trends among psychiatric hospitalizations between 2015-2019 finds that while most hospitalizations did not involve any substances, methamphetamine-related hospitalizations have increased while overall number of psychiatric hospitalizations remained stable. Fri, 16 Aug 2024 17:39:14 EDT https://www.sciencedaily.com/releases/2024/08/240816173914.htm https://www.sciencedaily.com/releases/2024/08/240814124451.htm A new implantable sensor could reverse opioid overdoses. The device rapidly releases naloxone when an overdose is detected. Wed, 14 Aug 2024 12:44:51 EDT https://www.sciencedaily.com/releases/2024/08/240814124451.htm https://www.sciencedaily.com/releases/2024/07/240729173344.htm A new study found that adults with chronic pain are more likely to experience symptoms of anxiety and depression than people without chronic pain, yet they access mental health care at lower rates and are less likely to have their mental health needs met in treatment. Mon, 29 Jul 2024 17:33:44 EDT https://www.sciencedaily.com/releases/2024/07/240729173344.htm https://www.sciencedaily.com/releases/2024/07/240725154730.htm Since 2009, U.S. high school seniors have reported steep declines in medical use, misuse and availability of the three most commonly prescribed and misused controlled substances for teens, a new study found. Thu, 25 Jul 2024 15:47:30 EDT https://www.sciencedaily.com/releases/2024/07/240725154730.htm https://www.sciencedaily.com/releases/2024/07/240724123119.htm Researchers have discovered a novel pain control pathway that links the cingulate cortex in the front of the brain, through the pons region of the brainstem, to cerebellum in the back of the brain. Wed, 24 Jul 2024 12:31:19 EDT https://www.sciencedaily.com/releases/2024/07/240724123119.htm https://www.sciencedaily.com/releases/2024/07/240717121049.htm Opioids have long been known as natural substances with substantial pharmacological effect. They have been used as effective painkillers. Researchers have now identified a natural active substance that may prove to be an effective alternative to opioids in the long run and could also help mitigate the opioid crisis. Wed, 17 Jul 2024 12:10:49 EDT https://www.sciencedaily.com/releases/2024/07/240717121049.htm https://www.sciencedaily.com/releases/2024/07/240717121032.htm Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose. Researchers have now identified a strategy to design safer opioids. They showed that an experimental opioid, which binds to an unconventional spot in the receptor, suppresses pain in animal models with fewer side effects -- most notably those linked to fatal overdoses. Wed, 17 Jul 2024 12:10:32 EDT https://www.sciencedaily.com/releases/2024/07/240717121032.htm https://www.sciencedaily.com/releases/2024/07/240716202304.htm Researchers have identified a new way to make opioids safer, increasing the pain-relieving properties of opioids while decreasing unwanted side effects through the spinal inhibition of a Heat shock protein 90 isoform. Tue, 16 Jul 2024 20:23:04 EDT https://www.sciencedaily.com/releases/2024/07/240716202304.htm https://www.sciencedaily.com/releases/2024/07/240715103350.htm New research could transform how we understand the way opioids affect the brain. Despite significant discussion surrounding the ongoing opioid crisis, current understanding of how opioids function in the brain is quite limited. This is primarily due to challenges in observing and measuring opioid effects in the brain in real-time. However, a recent technological breakthrough has overcome these limitations and is set to transform how scientists study opioid signaling in the brain. Mon, 15 Jul 2024 10:33:50 EDT https://www.sciencedaily.com/releases/2024/07/240715103350.htm https://www.sciencedaily.com/releases/2024/07/240711111405.htm A multi-institutional study found that 1 in 6 youths fill an opioid prescription prior to surgery, and 3% of patients were still filling opioid prescriptions three to six months after surgery, indicating persistent opioid use and possible opioid dependence. The study underscores that more guidance is needed to steer clinicians away from prescribing opioids when they are not likely to be needed and recognizing patient-specific risk factors for persistent opioid use. Thu, 11 Jul 2024 11:14:05 EDT https://www.sciencedaily.com/releases/2024/07/240711111405.htm https://www.sciencedaily.com/releases/2024/07/240709184237.htm Even years after they have recovered, a person who once struggled with alcohol or opioid addiction can relapse--and that relapse is more likely to occur during particularly stressful times. Now, scientists have identified an area of the brain that plays a key role in stress-induced oxycodone relapse. Their findings explain why the drug suvorexant, which they previously found to reduce alcohol and oxycodone relapse when administered orally, works so well. Tue, 09 Jul 2024 18:42:37 EDT https://www.sciencedaily.com/releases/2024/07/240709184237.htm https://www.sciencedaily.com/releases/2024/07/240709121705.htm New research has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief. Tue, 09 Jul 2024 12:17:05 EDT https://www.sciencedaily.com/releases/2024/07/240709121705.htm https://www.sciencedaily.com/releases/2024/07/240703131720.htm Researchers have identified a compound that, in mice, makes naloxone much more effective at counteracting a drug overdose. Wed, 03 Jul 2024 13:17:20 EDT https://www.sciencedaily.com/releases/2024/07/240703131720.htm https://www.sciencedaily.com/releases/2024/06/240617173443.htm Researchers found that among a cohort of 137,000 Medicare beneficiaries who experienced a nonfatal overdose in 2020, almost 24,000 (17.4%) experienced a subsequent nonfatal overdose, and about 1,300 (1%) died from overdose in the following year. Mon, 17 Jun 2024 17:34:43 EDT https://www.sciencedaily.com/releases/2024/06/240617173443.htm https://www.sciencedaily.com/releases/2024/06/240605162418.htm Scientists have found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids. Wed, 05 Jun 2024 16:24:18 EDT https://www.sciencedaily.com/releases/2024/06/240605162418.htm https://www.sciencedaily.com/releases/2024/06/240604184208.htm Adolescents with an internet addiction undergo changes in the brain that could lead to additional addictive behavior and tendencies, finds a new study. Tue, 04 Jun 2024 18:42:08 EDT https://www.sciencedaily.com/releases/2024/06/240604184208.htm https://www.sciencedaily.com/releases/2024/05/240529144015.htm Researchers have successfully tested a novel technique for probing deep into the human brain, without surgery, for potential therapeutic purposes. In the rapidly evolving field of neuroscience, non-invasive brain stimulation is a new hope for understanding and treating a myriad of neurological and psychiatric conditions without surgical intervention or implants. Wed, 29 May 2024 14:40:15 EDT https://www.sciencedaily.com/releases/2024/05/240529144015.htm https://www.sciencedaily.com/releases/2024/05/240508113058.htm Starting people with opioid use disorder on extended-release, injectable naltrexone (XR-naltrexone) within five to seven days of seeking treatment is more effective than the standard treatment method of starting within 10-15 days, but requires closer medical supervision, according to results from a clinical trial. The findings suggest that this rapid treatment protocol could make XR-naltrexone more viable as a treatment option for opioid use disorder, which continues to take lives at an alarming rate. Wed, 08 May 2024 11:30:58 EDT https://www.sciencedaily.com/releases/2024/05/240508113058.htm https://www.sciencedaily.com/releases/2024/04/240418165147.htm Researchers have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems. Thu, 18 Apr 2024 16:51:47 EDT https://www.sciencedaily.com/releases/2024/04/240418165147.htm https://www.sciencedaily.com/releases/2024/04/240417182736.htm The US saw a 22% decline in rates of prescription-opioid overdose related emergency department (ED) visits in children 17 and younger between 2008 and 2019, but an uptick in the early part of the COVID-19 pandemic, according to a new study. The authors also note that rates of pediatric opioid overdoses remain high in many populations. Wed, 17 Apr 2024 18:27:36 EDT https://www.sciencedaily.com/releases/2024/04/240417182736.htm https://www.sciencedaily.com/releases/2024/04/240412113052.htm Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a closer look at the molecular mechanisms of these active substances. Fri, 12 Apr 2024 11:30:52 EDT https://www.sciencedaily.com/releases/2024/04/240412113052.htm https://www.sciencedaily.com/releases/2024/01/240110120223.htm Reducing stimulant use was associated with significant improvement in measures of health and recovery among people with stimulant use disorder, even if they did not achieve total abstinence. This finding is according to an analysis of data from 13 randomized clinical trials of treatments for stimulant use disorders involving methamphetamine and cocaine. Wed, 10 Jan 2024 12:02:23 EST https://www.sciencedaily.com/releases/2024/01/240110120223.htm https://www.sciencedaily.com/releases/2023/12/231207161336.htm Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows. Overall, the rate of surgery-related opioid prescriptions dropped by 36% from 2016 to the end of 2022, and the average amount of opioids in those prescriptions dropped by 46%. Thu, 07 Dec 2023 16:13:36 EST https://www.sciencedaily.com/releases/2023/12/231207161336.htm https://www.sciencedaily.com/releases/2023/11/231129112524.htm A 20-year study examined the long term relationship between cannabis and illicit opioid use. Overall results were inconsistent and showed no strong link. The study showed that clinicians and policymakers should be cautious about relying on cannabis to reduce opioid use, especially in the US and Canada. Wed, 29 Nov 2023 11:25:24 EST https://www.sciencedaily.com/releases/2023/11/231129112524.htm