Mice News

June 15, 2024

Top Headlines

Gonadal Function in Male Mice Disrupted by Prenatal Risk Factors

June 14, 2024 — Researchers have consistently shown that prenatal exposure to Di (2-ethyhexyl) phthalate harms the reproductive system in male mice and causes fertility defects. In a new study, scientists have shown that the combination of DEHP and a high-fat diet ...

The Genetic 'Switches' of Bone Growth

June 14, 2024 — In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are ...

Fasting Primes the Immune System's Natural Killer Cells to Better Fight Cancer, New Study in Mice Finds

June 14, 2024 — A team of researchers has shown for the first time that fasting can reprogram the metabolism of natural killer cells, helping them to survive in the harsh environment in and around tumors, while also ...

First Week After Birth Is Critical for Development of Senses

June 11, 2024 — Researchers have found that the maturation of the senses for smell and touch is closely linked in mice and that this strong interaction takes place within a narrow developmental time window. These findings not only underline the importance of ...

Latest Headlines

updated 7:02pm EDT

Brain's Structure Hangs in 'a Delicate Balance'

June 10, 2024 — Researchers examined anatomy of neurons from humans, mice and fruit flies. They discovered that the cellular structure of the brain is at a critical point, poised between two phases. New insights ...

Gut Microbes from Aged Mice Induce Inflammation in Young Mice, Study Finds

June 10, 2024 — When scientists transplanted the gut microbes of aged mice into young 'germ-free' mice -- raised to have no gut microbes of their own -- the recipient mice experienced an increase in inflammation ...

Exercising During Pregnancy Normalizes Eating Behaviors in Offspring from Obese Mice

June 4, 2024 — Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new ...

New, Modified CRISPR Protein Can Fit Inside Virus Used for Gene Therapy

May 30, 2024 — Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver ...

Unlocking the World Around Us for Next-Gen Antibiotics

June 5, 2024 — An international research team has found almost a million potential sources of antibiotics in the natural ...

Myelination in the Brain May Be Key to 'Learning' Opioid Addiction

June 5, 2024 — Scientists have found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to ...

Father's Diet Before Conception Influences Children's Health

June 5, 2024 — A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health ...

An Anti-Inflammatory Curbs Spread of Fungi Causing Serious Blood Infections

June 4, 2024 — Study finds that mesalamine, a common anti-inflammatory drug, can fight the fungus Candida albicans in the gut, potentially preventing the risk of invasive candidiasis in patients with blood ...

Oral Nucleoside Antiviral Is Progressing Toward Future Pandemic Preparedness

June 3, 2024 — Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future ...

Lighting Up the Brain: What Happens When Our 'Serotonin Center' Is Triggered?

May 31, 2024 — Scientists have studied the main source of serotonin in the brain -- the dorsal raphe nucleus (DRN). By studying how activating the brain's ...

Scientists Invent 'Living Bioelectronics' That Can Sense and Heal Skin

May 30, 2024 — Reaserchers have created a prototype for what they call 'living bioelectronics': a combination of living cells, gel, and electronics that can integrate with living tissue. Tests in mice ...

Blood Flow Makes Waves Across the Surface of the Mouse Brain

May 29, 2024 — Researchers have, for the first time, visualized the full network of blood vessels across the cortex of awake mice, finding that blood vessels rhythmically expand and contract leading to ...

New Antibiotic Kills Pathogenic Bacteria, Spares Healthy Gut Microbes

May 29, 2024 — Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse ...

Bird Flu: Diverse Range of Vaccines Platforms 'Crucial' for Enhancing Human Pandemic Preparedness

May 29, 2024 — Review of research to-date suggests vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across ...

How Killifish Embryos Use Suspended Animation to Survive Over 8 Months of Drought

May 28, 2024 — The African turquoise killifish lives in ephemeral ponds in Zimbabwe and Mozambique. To survive the annual dry season, the fish's embryos enter a state of extreme suspended animation or ...

High H5N1 Influenza Levels Found in Mice Given Raw Milk from Infected Dairy Cows

May 24, 2024 — Mice administered raw milk samples from dairy cows infected with H5N1 influenza experienced high virus levels in their respiratory organs and lower virus levels in other vital organs, according to ...

Tracking Down the Genetic Causes of Lupus to Personalize Treatment

May 23, 2024 — Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these ...

Sweet Move: A Modified Sugar Enhances Antisense Oligonucleotide Safety and Efficacy

May 22, 2024 — Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their ...

Naturally Occurring Substance in Pomegranates Can Improve Treatment of Alzheimer's Disease

May 22, 2024 — A substance naturally occurring in i.a. pomegranates, strawberries and walnuts can improve memory and treatment of Alzheimer's disease, a new study ...

Hope for a Cure for Visceral Leishmaniasis, an Often Fatal Infectious Disease

May 21, 2024 — Leishmaniasis is a tropical disease affecting a growing number of people worldwide. Each year, between 700,000 and 1 million new cases are reported. Caused by a protozoan parasite of the genus ...

Clarifying the Cellular Mechanisms Underlying Periodontitis With an Improved Animal Model

May 21, 2024 — Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed ...

Chronic Wasting Disease Unlikely to Move from Animals to People

May 17, 2024 — A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD) from cervids -- deer, ...

Exploring the Mechanism Behind Drug Eruptions in the Skin

May 15, 2024 — Although drug eruptions are often linked to the human leukocyte antigen (HLA), the mechanism of its involvement in presenting symptoms of the skin remains unclear. In a recent study, researchers used ...

Some Mice May Owe Their Monogamy to a Newly Evolved Type of Cell

May 15, 2024 — What makes the oldfield mouse steadfastly monogamous throughout its life while its closest rodent relatives are promiscuous? The answer may be a previously unknown hormone-generating cell. Scientists ...

Plant Virus Treatment Shows Promise in Fighting Metastatic Cancers in Mice

May 13, 2024 — An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study. The treatment, composed of nanoparticles fashioned ...

New Tool to Boost Battle Against Childhood Undernutrition

May 10, 2024 — The tool will help researchers better understand major challenges that afflict undernourished children, such as changes in cognitive development and higher infection ...

Brain Mechanisms Underlying Sensory Hypersensitivity in a Mouse Model of Autism Spectrum Disorder

May 9, 2024 — A research team has identified the primary cause of sensory hypersensitivity in a mouse model of autism spectrum disorders ...

Intermittent Fasting Protects Against Liver Inflammation and Liver Cancer

May 7, 2024 — Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists have now shown in mice that intermittent fasting on a 5:2 schedule can halt this ...

How a 'Conductor' Makes Sense of Chaos in Early Mouse Embryos

May 7, 2024 — The earliest stages of mammalian embryo development are like an orchestra performance, where everyone must play at the exact right moment and in perfect harmony. New research identifies one of the ...

Using Advanced Genetic Techniques, Scientists Create Mice With Traits of Tourette Disorder

May 6, 2024 — In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists have bred mice that exhibit some of the same behaviors and brain abnormalities seen in ...