Colitis News

June 15, 2024

Top Headlines

Putting the Brakes on Chronic Inflammation

June 12, 2024 — Scientists have discovered a previously unknown link between two key pathways that regulate the immune system in mammals -- a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD). This family of disorders severely ...

An AI-Powered Wearable System Tracks the 3D Movement of Smart Pills in the Gut

June 12, 2024 — Scientists have developed an artificial intelligence (AI)-powered system to track tiny devices that monitor markers of disease in the gut. Devices using the novel system may help at-risk individuals ...

Lab-Grown 'Mini-Guts' Could Help in Development of New and More Personalized Treatments for Crohn's Disease

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in ...

Gut Microbes from Aged Mice Induce Inflammation in Young Mice, Study Finds

June 10, 2024 — When scientists transplanted the gut microbes of aged mice into young 'germ-free' mice -- raised to have no gut microbes of their own -- the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with ...

Latest Headlines

updated 10:45pm EDT

Major Cause of Inflammatory Bowel Disease Discovered

June 5, 2024 — Researchers have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing ...

An Anti-Inflammatory Curbs Spread of Fungi Causing Serious Blood Infections

June 4, 2024 — Study finds that mesalamine, a common anti-inflammatory drug, can fight the fungus Candida albicans in the gut, potentially preventing the risk of invasive candidiasis in patients with blood ...

Computational Insights Into Colonic Motility to Aid Understanding of Ulcerative Colitis

June 3, 2024 — Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis ...

Researchers Uncover Surprising Role of Opioid Receptors in Gut Development

May 29, 2024 — Researchers have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the 'brain in the gut.' This discovery ...

New Antibiotic Kills Pathogenic Bacteria, Spares Healthy Gut Microbes

May 29, 2024 — Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse ...

Celiac Disease: New Findings on the Effects of Gluten

May 16, 2024 — Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population. It is triggered by the consumption of gluten proteins from wheat, barley, rye and some ...

Identifying a New Liver Defender: The Role of Resident Macrophages

Apr. 25, 2024 — Researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal ...

Apply Single-Cell Analysis to Reveal Mechanisms of a Common Complication of Crohn's Disease

Apr. 24, 2024 — Study identifies key pathways underlying perianal fistula, a disease complication that is more prevalent and severe in African American ...

Scientists Discover the Cellular Functions of a Family of Proteins Integral to Inflammatory Diseases

Apr. 22, 2024 — In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) ...

Dietary Treatment More Effective Than Medicines in IBS

Apr. 19, 2024 — Dietary treatment is more effective than medications in irritable bowel syndrome (IBS). With dietary adjustments, more than seven out of ten patients had significantly reduced ...

New Inflammatory Bowel Disease Testing Protocol Could Speed Up Diagnosis

Apr. 16, 2024 — Patients with suspected inflammatory bowel disease (IBD) could benefit from better testing protocols that would reduce the need and lengthy wait for potentially unnecessary colonoscopies, a new study ...

Microplastics Make Their Way from the Gut to Other Organs

Apr. 15, 2024 — Researchers have found that microplastics -- are having a significant impact on our digestive pathways, making their way from the gut and into the tissues of the kidney, liver and ...

Treatment With Anti-Inflammatory Proteins Following Heart Attack Shows Promise to Reduce the Risk of Further Heart Damage

Apr. 4, 2024 — Research into the protective effects of two anti-inflammatory molecules, transforming growth factor-beta1 (TGF 1) and Heligmosomoides polygyrus TGM (HpTGM), following heart attack found that both ...

Hope for Treating Autoimmune Diseases

Apr. 3, 2024 — A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases. The Systemic Inflammation ...

Gene Analysis Generates Spatial Map of Intestinal Cells and Traces Their Trajectories During Gut Inflammation

Apr. 2, 2024 — Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis. Certain chronic disorders are distinctly characterized by gut inflammation, ...

Scientists Pioneer Immunotherapy Technique for Autoimmune Diseases

Apr. 1, 2024 — Scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune ...

Fiber, Genes and the Gut Microbiome: Study Reveals Possible Triggers for Inflammatory Bowel Disease

Mar. 20, 2024 — A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD ...

Implantable Sensor Could Lead to Timelier Crohn's Treatment

Mar. 18, 2024 — Scientists have developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn's disease. The approach offers long-term, real-time monitoring ...

Gut Bacteria Make Neurotransmitters to Shape the Newborn Immune System

Mar. 15, 2024 — Investigators discovered that unique bacteria colonize the gut shortly after birth and make the neurotransmitter serotonin to educate gut immune cells. This prevents allergic reactions to food and ...

New Understanding of the Gut Immune System May Hold Promise for Crohn's Disease Patients

Mar. 15, 2024 — Scientists uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn's disease. The discovery may help define how to treat patients with severe ...

A Sprayable Gel Could Make Minimally Invasive Surgeries Simpler and Safer

Mar. 12, 2024 — The new GastroShield gel can be sprayed through an endoscope after polyps are removed during colonoscopy, protecting the gut and helping prevent complications from weakened gastrointestinal ...

Gut-Brain Communication Turned on Its Axis

Feb. 26, 2024 — The mechanisms by which antidepressants and other emotion-focused medications work could be reconsidered due to an important new breakthrough in the understanding of how the gut communicates with the ...

Treating Newly-Diagnosed Crohn's Patients With Advanced Therapy Leads to Dramatic Improvements in Outcomes

Feb. 22, 2024 — A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, ...

Scientists Discover Link Between Leaky Gut and Accelerated Biological Aging

Feb. 21, 2024 — A professor has demonstrated a connection between viral damage to the gut and premature biological ...

Fecal Microbiota Transplant Recommended for the Majority of Recurrent C. Diff Patients

Feb. 21, 2024 — In the first comprehensive evidence-based guideline on the use of fecal microbiota-based therapies for gastrointestinal disease, the American Gastroenterological Association recommends fecal ...

Do Sugar-Free Candy and Gum Give You Gas? Researchers Think They Know Why

Feb. 15, 2024 — Scientists may have figured out why some people have trouble digesting sorbitol, a sugar alcohol used in sugar-free gum, mints, candy and other ...

Nutrients Direct Intestinal Stem Cell Function and Affect Aging

Feb. 12, 2024 — The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal ...

Healthy Diet Early in Life Seems to Protect Against Inflammatory Bowel Disease

Jan. 31, 2024 — Having a high dietary intake of fish and vegetables at 1 year of age, and a low intake of sugar beverages, seems to protect against inflammatory bowel disease. These are the findings of a study with ...

Mood Interventions May Reduce Inflammation in Crohn's and Colitis

Jan. 24, 2024 — New research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood ...

Researchers Identify Why Cancer Immunotherapy Can Cause Colitis

Jan. 5, 2024 — Researchers have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment, also finding a way to deliver immunotherapy's cancer-killing impact ...