Featured Research

from universities, journals, and other organizations

Formal Education Lessens Impact Of Alzheimer’s Disease -- Even If Brain Volume Is Already Reduced

Date:
August 12, 2009
Source:
IOS Press
Summary:
Researchers in Europe investigated the effects of formal education on the symptoms of Alzheimer's disease. They were able to show that education diminishes the impact of Alzheimer's disease on cognition even if a manifest brain volume loss has already occurred.

Researchers at the Department of Psychiatry, Klinikum rechts der Isar, Technische Universitδt Mόnchen, investigated the effects of formal education on the symptoms of Alzheimer's disease. They were able to show that education diminishes the impact of Alzheimer's disease on cognition even if a manifest brain volume loss has already occurred.

The results are published in the current issue of the Journal of Alzheimer's Disease.

Dr. Robert Perneczky, Department of Psychiatry at Klinikum rechts der Isar explains: "We know that there is not always a close association between brain damage due to Alzheimer's disease and the resulting symptoms of dementia. In fact, there are individuals with severe brain pathology with almost no signs of dementia, whereas others with only minor brain lesions exhibit a considerable degree of clinical symptoms."

These phenomena are often ascribed to the theoretical concept of cognitive reserve. A high level of cognitive reserve results in a strong individual resilience against symptoms of brain damage; cognitive reserve can therefore be seen as protective against brain damage.

In support of this, previous studies demonstrated that duration of formal education is associated with cognitive reserve such that comparison of individuals with the same degree of brain damage shows that those with more years of formal education suffer from less severe symptoms of dementia.

Prior to the current study, brain damage was assessed after death using brain autopsy measures or using very sensitive functional imaging measures in live individuals.

Perneczky comments: "Our study is the first to show that formal education also modifies the association between brain damage and clinical symptoms of dementia in Alzheimer's disease if brain damage is defined as volume loss on magnetic resonance imaging scans. The relevance of our findings is strengthened by the large sample including 270 patients with Alzheimer's disease. Furthermore, factors with a potential negative influence on cognition and brain volume loss, such as genetic characteristics, age, gender, and brain infarction were also considered."

These research results show for the first time that the modifying effect of formal education is robust enough to reduce the negative effects of structural brain damage on cognitive function. Further studies are planned that will include a larger patient cohort and more precise measurement of brain volume reduction.


Story Source:

The above story is based on materials provided by IOS Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. Perneczky R, Wagenpfeil S, Lunetta KL, Cupples LA, Green RC, Decarli C, Farrer LA, Kurz A. Education Attenuates the Effect of Medial Temporal Lobe Atrophy on Cognitive Function in Alzheimer's Disease: The MIRAGE Study. J Alzheimers Dis, 17:4 (August 2009)

Cite This Page:

IOS Press. "Formal Education Lessens Impact Of Alzheimer’s Disease -- Even If Brain Volume Is Already Reduced." ScienceDaily. ScienceDaily, 12 August 2009. <www.sciencedaily.com/releases/2009/08/090811161339.htm>.
IOS Press. (2009, August 12). Formal Education Lessens Impact Of Alzheimer’s Disease -- Even If Brain Volume Is Already Reduced. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2009/08/090811161339.htm
IOS Press. "Formal Education Lessens Impact Of Alzheimer’s Disease -- Even If Brain Volume Is Already Reduced." ScienceDaily. www.sciencedaily.com/releases/2009/08/090811161339.htm (accessed September 2, 2014).

Share This




More Mind & Brain News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) — New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
Coffee Then Napping: The (New) Key To Alertness

Coffee Then Napping: The (New) Key To Alertness

Newsy (Aug. 30, 2014) — Researchers say having a cup of coffee then taking a nap is more effective than a nap or coffee alone. Video provided by Newsy
Powered by NewsLook.com
Young Entrepreneurs Get $100,000, If They Quit School

Young Entrepreneurs Get $100,000, If They Quit School

AFP (Aug. 29, 2014) — Twenty college-age students are getting 100,000 dollars from a Silicon Valley leader and a chance to live in San Francisco in order to work on the start-up project of their dreams, but they have to quit school first. Duration: 02:20 Video provided by AFP
Powered by NewsLook.com
Baby Babbling Might Lead To Faster Language Development

Baby Babbling Might Lead To Faster Language Development

Newsy (Aug. 29, 2014) — A new study suggests babies develop language skills more quickly if their parents imitate the babies' sounds and expressions and talk to them often. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins