Cancer News
September 4, 2015

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updated 10:53am EDT

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September 4, 2015

Sep. 3, 2015 — In the breast, cancer stem cells and normal stem cells can arise from different cell types and tap into distinct yet related stem cell programs, according to researchers. The differences between ... read more

Drug for Fungal Infections in Lung Transplant Recipients Increases Risk for Cancer, Death

Sep. 3, 2015 — Voriconazole, a prescription drug commonly used to treat fungal infections in lung transplant recipients, significantly increases the risk for skin cancer and even death, according to a new ... read more

Telomerase Targeting Drug Demonstrates Benefit in Myelofibrosis Treatment

Sep. 2, 2015 — Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a new ... read more

Cellular Recycling Complexes May Hold Key to Chemotherapy Resistance

Sep. 2, 2015 — Upsetting the balance between protein synthesis, misfolding, and degradation drives cancer and neurodegeneration. Recent cancer treatments take advantage of this knowledge with a class of drugs that ... read more

Researchers Develop a Likely New Combo Treatment for the Deadliest Form of Brain Cancer

Sep. 1, 2015 — Scientists have developed a potentially promising new combination therapy for glioblastoma, the deadliest form of brain cancer. Glioblastoma, also known as grade IV glioma, is the most aggressive ... read more

New Treatment Strategy Identified for Tumors Associated With Diabetes

Sep. 1, 2015 — If you have diabetes and cancer, here's some hope. In a new research report, scientists reveal a newly discovered tissue- and organ-specific mechanism that regulates blood vessel growth, and ... read more

Sep. 1, 2015 — Statins are a popular and easy-to-swallow option for people looking to lower their cholesterol. But for a quarter of patients, statins come with muscle pain, stiffness, cramps, or weakness without ... read more

Genetic Landscape Can Impact Treatment for Children With Rare, Aggressive Cancer

Sep. 1, 2015 — For children with rare, aggressive and advanced cancer, precision medicine may help doctors determine their best treatment options, a new study finds. Using information from a patient’s entire ... read more

Modified CAR T Cells Can Preferentially Target Cancer Cells, Spare Normal Cells

Sep. 1, 2015 — Engineering chimeric antigen receptor (CAR) T cells to lower their affinity for the protein epithelial growth factor receptor (EGFR) made the cells preferentially recognize and eliminate tumor cells ... read more

Newly Engineered CAR T Cells Can Better Discriminate Between Cancer and Normal Cells

Sep. 1, 2015 — A new development in engineering chimeric antigen receptor (CAR) T cells, called affinity tuning, can make the CAR T cells spare normal cells and better recognize and attack cancer cells, which may ... read more

Statistical Model May Identify Patients Most Likely to Benefit from Surgery for Mesothelioma

Sep. 1, 2015 — A new statistical model may help predict which patients are most likely to receive life-extending benefits from surgical treatment for malignant pleural mesothelioma, scientists ... read more

Some With Low-Risk Prostate Cancer Not Likely to Succumb to the Disease

Aug. 31, 2015 — Men with relatively unaggressive prostate tumors and whose disease is carefully monitored by urologists are unlikely to develop metastatic prostate cancer or die of their cancers, according to ... read more

Researchers Examine Risk Factors/patient Outcomes Associated With Colorectal Cancer

Aug. 31, 2015 — About 20 percent of colorectal cancer patients have cancers that have spread beyond the colon at the time of their diagnosis. In a new study, researchers provide a detailed comparison of patient ... read more

Aug. 31, 2015 — HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to research. In the study, researchers analyzed large sample sets ... read more

Aug. 31, 2015 — Blocking glycolysis -- the molecular mechanism that makes it possible to extract energy from glucose -- is especially damaging to the division of cancer cells, research shows. Specifically acting on ... read more

'Eat Me' Signal Whets Appetites for Tumor-Devouring Dendritic Cells

Aug. 31, 2015 — The therapeutic effect of CD47 blockade as a cancer treatment relies more on dendritic cells than macrophages, scientists report. Anti-CD47-mediated tumor rejection will require both innate and ... read more

Fatal Bleeding Rare With Extended Dual Antiplatelet Therapy

Aug. 31, 2015 — Fatal bleeding is rare with extended dual antiplatelet therapy, according to a secondary analysis of the DAPT Study. Bleeding-related mortality accounted for a minority of deaths in patients treated ... read more

Aug. 31, 2015 — Cancer cells survive the stressful environment inside a tumor in part through autophagy, the controlled digestion and recycling of damaged components. However, blocking the process doesn't kill ... read more

Research Team Creates Model to Predict Cellular Evolution

Aug. 31, 2015 — Scientists have not been able to understand and predict how cells evolve in our bodies, and this process is important because evolving cell populations are at the core of drug-resistant infections ... read more

New Synthetic Tumor Environments Make Cancer Research More Realistic

Aug. 28, 2015 — Tumors are notoriously difficult to study in their natural habitat -- body tissues -- but a new synthetic tissue environment may give cancer researchers the next-best look at tumor growth and ... read more

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