Featured Research

from universities, journals, and other organizations

New biological find gives consequences for doping offence

Date:
August 20, 2010
Source:
University of Oslo
Summary:
Exercise induces the incorporation of nuclei in muscle fibers that may help the fibers regain size upon retraining after a period of atrophy brought on by muscle disuse, according to a study. Exercise enthusiasts know all too well that strength training of muscles leads to an increase in muscle size that is lost when the training is discontinued; the muscle fibers atrophy because of inactivity. But the mechanism by which previous episodes of training help atrophied fibers regain size relatively soon after retraining has long remained a mystery.

Exercise induces the incorporation of nuclei in muscle fibers that may help the fibers regain size upon retraining after a period of atrophy brought on by muscle disuse, according to a study.

Exercise enthusiasts know all too well that strength training of muscles leads to an increase in muscle size that is lost when the training is discontinued; the muscle fibers atrophy because of inactivity. But the mechanism by which previous episodes of training help atrophied fibers regain size relatively soon after retraining has long remained a mystery.

Professor Kristian Gundersen and colleagues at the Department of Molecular Biosciences, University of Oslo conducted imaging experiments on rodent muscles to find the cellular substrate for such 'muscle memory.'

After an episode of overload exercise that resembled strength training, new nuclei were added to muscle fibers before the fibers grew in size, the authors found. The fibers retained the nuclei for a considerable time of the mouse life span after the overload was discontinued, the authors report. In addition, the nuclei helped delay muscle atrophy. Because the ability to create new muscle nuclei wanes with age, people may benefit from strength training at an early age, the authors suggest.

Further, the relatively long-lasting muscle memory, likely encoded by the nuclei, implies that the length of time for which athletes are banned for a doping offense may need to be reevaluated, according to the authors.


Story Source:

The above story is based on materials provided by University of Oslo. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. C. Bruusgaard, I. B. Johansen, I. M. Egner, Z. A. Rana, K. Gundersen. Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining. Proceedings of the National Academy of Sciences, 2010; DOI: 10.1073/pnas.0913935107

Cite This Page:

University of Oslo. "New biological find gives consequences for doping offence." ScienceDaily. ScienceDaily, 20 August 2010. <www.sciencedaily.com/releases/2010/08/100819074449.htm>.
University of Oslo. (2010, August 20). New biological find gives consequences for doping offence. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2010/08/100819074449.htm
University of Oslo. "New biological find gives consequences for doping offence." ScienceDaily. www.sciencedaily.com/releases/2010/08/100819074449.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins