Featured Research

from universities, journals, and other organizations

Effective Acne Treatments Remain Elusive, Hopkins Researchers Find

Date:
April 26, 2001
Source:
Johns Hopkins Medical Institutions
Summary:
After a half-century of looking at everything from Accutane to zinc, dermatologists still can't prove which acne treatments and drugs work best, a team at Johns Hopkins Children's Center finds after combing the scientific literature.

After a half-century of looking at everything from Accutane to zinc, dermatologists still can't prove which acne treatments and drugs work best, a team at Johns Hopkins Children's Center finds after combing the scientific literature.

"One of the key questions for dermatologists has been, ‘How should we be treating acne in any given case?'" says pediatrician and medical informatics specialist Harold Lehmann, M.D., Ph.D. "Here we are in the 21st century and we still don't have a clear answer to that question."

Lehmann and his co-authors document the dilemma in a so-called evidence report for the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality (AHRQ). The reports are designed to give the public state-of-the-science information about important health topics.

AHRQ asked Hopkins to analyze the relevant scientific literature and identify the best drugs for treating acne and to determine the strength of acne research findings based on predetermined criteria. The team selected 250 English-language studies that compared 150 acne drugs to each other or to a placebo.

Each study was categorized and rated according to details of how the study was performed, including how patients' acne was assessed and if statistical significance was achieved in each experimental comparison. After rating all the studies, the research team found only 14 of the studies met their criteria for a high "level of evidence", while the other 236 studies were almost equally divided between middle and low levels of evidence based on the group's criteria. "Some of the medicines in the studies we looked at seemed to work quite well," Lehmann says. "But it was impossible to say which medicines were the best for a specific acne condition."

Lehmann suggests that a lack of research standards and a deficiency of studies comparing drugs directly to each other might be to blame for the lack of consensus on best acne therapies.

"Dermatologists know a lot about acne," Lehmann says. "But without standards and guidelines for dermatological research, it's extremely hard to compare one study to another and learn which treatments are best."

Lehmann will work with members of the American Association of Pediatrics and the American Dermatological Society in May to create research standards and guidelines dermatologists can follow to help build consensus on favored acne treatments.

Funding for the report was provided by the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality. Other researchers contributing to the report were Johns Hopkins researchers John Andrews, M.D., Karen Robinson, M.Sc., Victoria Holloway M.D., M.P.H., Steven Goodman, M.D., Ph.D.


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Effective Acne Treatments Remain Elusive, Hopkins Researchers Find." ScienceDaily. ScienceDaily, 26 April 2001. <www.sciencedaily.com/releases/2001/04/010418072759.htm>.
Johns Hopkins Medical Institutions. (2001, April 26). Effective Acne Treatments Remain Elusive, Hopkins Researchers Find. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2001/04/010418072759.htm
Johns Hopkins Medical Institutions. "Effective Acne Treatments Remain Elusive, Hopkins Researchers Find." ScienceDaily. www.sciencedaily.com/releases/2001/04/010418072759.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
American Ebola Patient Apparently Improving, Outbreak Is Not

American Ebola Patient Apparently Improving, Outbreak Is Not

Newsy (Aug. 19, 2014) Nancy Writebol, an American missionary who contracted Ebola, is apparently getting better, according to her husband. The outbreak, however, is not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins