Genes News
October 13, 2015

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October 13, 2015

Researchers Use Gut Bacteria Composition to Genetically Classify Colorectal Tumors

Oct. 9, 2015 — By analyzing the types of gut bacteria present around colorectal tumors, researchers have found a way to predict key genetic mutations in the tumors themselves, a method that could eventually inform ... read more

Oct. 9, 2015 — Genomicists have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone. The researchers show that a new nanopore sequencer can ... read more

Researchers Gauge Heritability of Childhood-Onset Autoimmune Diseases

Oct. 9, 2015 — Scientists have calculated more precise measurements of heritability -- the influence of underlying genes -- in nine autoimmune diseases that begin in childhood. The research may strengthen ... read more

Immune Gene Prevents Parkinson's Disease, Dementia

Oct. 9, 2015 — An estimated seven to ten million people worldwide are living with Parkinson's disease (PD). More than half of PD patients develop progressive disease showing signs of dementia similar to ... read more

Common Gene Variant Linked to Chromosome Errors, Early Pregnancy Loss

Oct. 8, 2015 — Researchers have identified a common genetic variant strongly associated with chromosome gains and losses during the early stages of human embryonic development. These errors in cell division, which ... read more

Researchers Create 'Leukemia in a Dish' to Better Study It

Oct. 8, 2015 — Scientists engineered stem cells to better understand the mechanisms behind a form of leukemia caused by changes in a key gene, according to a new ... read more

A Convergence of Deadly Signals

Oct. 8, 2015 — A team of Ludwig Cancer Research scientists has mapped out how a mutant version of the epidermal growth factor receptor (EGFR) known as EGFRvIII specifically drives critical processes that alter the ... read more

Oct. 8, 2015 — Biochemists have long known that crucial cell processes depend on a highly regulated cleanup system known as proteolysis, where specialized proteins called proteases degrade damaged or ... read more

Genetic Variation Is Key to Fighting Viruses

Oct. 8, 2015 — Using a genome-wide association study, scientists have identified subtle genetic changes that can cause substantial differences to how we fight viral infections. The new work connects genetics to ... read more

Oct. 8, 2015 — Our cells contain proteins, essential to functions like protein creation and DNA repair but also involved in forms of ALS and cancer, that never take a characteristic shape, a new study shows. ... read more

Breast Cancer Genomic Analysis Reveals Invasive Lobular Carcinoma Subtypes

Oct. 8, 2015 — Researchers analyzed hundreds of breast cancer samples to reveal genetic drivers of invasive lobular carcinoma, the second most commonly diagnosed invasive form of breast cancer. The work, the ... read more

Oct. 8, 2015 — A new technique allows scientists to study diseases like Alzheimer's and Parkinson's using cells from human patients. Historically, animal models -- from fruit flies to mice -- have been ... read more

Oct. 8, 2015 — Compared with direct gene injection, cell-mediated GDNF gene delivery led to considerably more pronounced preservation of myelinated fibers in the remote segments of the spinal cord (5 vs 3 mm from ... read more

Oct. 8, 2015 — The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers have found that the structure of translocations in cancer cells shows ... read more

'Alarm Clock' of a Leukemia-Causing Oncogene Identified

Oct. 8, 2015 — Mutations in DNMT3A gene cause MEIS1 activacion, triggering leukemia, a research team ... read more

Oct. 8, 2015 — The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers from the Universitat Autònoma de Barcelona have found that the ... read more

'Chromosomal Chaos:' Complex Array of Mutations Found in Rare, Aggressive Leukemia

Oct. 7, 2015 — Sezary syndrome (SS), an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected. With a poor prognosis and limited options for targeted therapies, this ... read more

Oct. 7, 2015 — In a hospital, what you can’t see could hurt you. Healthcare facilities continue to battle drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA) that loiter on ... read more

Researchers Develop Classification Model for Cancers Caused by Most Frequently Mutated Cancer Gene

Oct. 7, 2015 — Researchers have developed a classification for cancers caused by KRAS, the most frequently mutated gene in cancer, that could eventually help oncologists choose more effective, customized cancer ... read more

Shaking Up the Foundations of Epigenetics

Oct. 7, 2015 — Cells of multicellular organisms contain identical genetic material (the genome) yet can have drastic differences in their structural arrangements and functions. This variation of the distinct cell ... read more

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