Genes News
July 6, 2015

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More Genes News
July 6, 2015

Visualizing RNAi at Work

July 6, 2015 — Researchers have revealed the molecular mechanism of RNA interference (RNAi), the phenomenon by which the synthesis of a specific protein is inhibited, by real time observation of target RNA cleavage ... read more

July 6, 2015 — Researchers have identified modes of Sox9 action during cartilage formation by analyzing big data on Sox9 location, chromatin state, and gene expression over the whole mouse genome. This finding will ... read more

Colorectal Cancer: Second-Line Cetuximab Active Beyond Progression in Quadruple Wild-Type Patients With Mcrc

July 4, 2015 — Patients with metastatic colorectal cancer (mCRC) that are mutation-free in the KRAS, NRAS, BRAF and PIK3CA genes showed significant benefit from continuing anti-epidermal growth factor receptor ... read more

July 3, 2015 — The DNA molecule is chemically unstable giving rise to DNA lesions of different nature. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are ... read more

New Understanding of Retinoblastoma Proteins' Role in Cell Death and Cancer Progression

July 2, 2015 — A new review article focuses on RB role in apoptosis provides a comprehensive overview on the role of RB proteins in the coordinated control of cell ... read more

The Sting in Dengue's Tail

July 2, 2015 — Scientists have identified how small changes in dengue's viral genome can affect the virus' ability to manipulate human immune defenses and spread more ... read more

July 2, 2015 — Prions are fascinating, enigmatic, and might teach us not only about rare prion diseases like Creutzfeld-Jakob disease, mad cow disease, or scrapie, but also about other more common neurodgenerative ... read more

Genes May Not Be to Blame for Link Between Migraine, Heart Disease

July 2, 2015 — Genes may not be to blame for the increased risk of heart disease some studies have shown in people with migraine, especially those with migraine with aura, new research shows. Aura are sensations ... read more

July 2, 2015 — A team using electron cryomicroscopy has for the first time revealed at the atomic level the structure of a protein required for viral replication in vesicular stomatitis virus, a virus that is a ... read more

Genetic Variation Determines Response to Anti-Diabetic Drug

July 2, 2015 — In the first study of its kind, researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. They aim to ... read more

July 2, 2015 — Cartilage does a lot more than determine the shapes of people's ears and noses. It also enables people to breathe and to form healthy bones -- two processes essential to life. A new study ... read more

July 2, 2015 — In fruit flies, the abnormal growth induced by Hippo pathway disruption depends on genes involved in responding to the steroid hormone ecdysone. This has potential implications for human biology, ... read more

Telomeres Linked to Origins of Idiopathic Pulmonary Fibrosis

July 2, 2015 — Researchers have now discovered that telomeres, the structures that protect the chromosomes, are at the origin of pulmonary fibrosis. This is the first time that telomere damage has been identified ... read more

July 2, 2015 — Unveiling how the 20,000 or so proteins in the human body work -- and malfunction -- is the key to understanding much of health and disease. Now, researchers have developed a new technique that ... read more

Cause of Acute Liver Failure in Young Children Discovered

July 2, 2015 — Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent of cases it is ... read more

July 2, 2015 — Researchers report that the deletion of the PTEN gene would enhance compensatory sprouting of uninjured CST axons. Furthermore, the deletion up-regulated the activity of another gene, the mammalian ... read more

July 2, 2015 — Spider-like cells inside the brain, spinal cord and eye hunt for invaders, capturing and then devouring them. These cells, called microglia, often play a beneficial role by helping to clear trash and ... read more

Latent Virus and Life Expectancy

July 2, 2015 — Molecular, cellular and clinical changes that arise from an infection with a latent virus can result in a decrease in ... read more

July 1, 2015 — Oftentimes men with a type of infertility called azoospermia don't know the underlying cause of their condition. But new research suggests that mutations in an X chromosome gene called TEX11 are ... read more

Lifelong Learning Is Made Possible by Recycling of Histones, Study Says

July 1, 2015 — A new mechanism that makes neuronal plasticity and, as a result, learning possible has been discovered by researchers. This discovery centers on a specific type of histone, proteins that support DNA ... read more

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