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Testosterone deficiency affects male cancer survivors' quality of life

Date:
February 22, 2010
Source:
American Cancer Society
Summary:
A new study has found that many male cancer survivors who develop testosterone deficiency after receiving chemotherapy or radiation therapy have an impaired quality of life and reduced energy levels.

A new study has found that many male cancer survivors who develop testosterone deficiency after receiving chemotherapy or radiation therapy have an impaired quality of life and reduced energy levels. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study suggests that young male cancer survivors with testosterone deficiency may benefit from testosterone replacement therapy.

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Testosterone deficiency is a late side effect of radiation therapy and chemotherapy that occurs in approximately 15 percent of male cancer survivors. Investigators led by Professor Richard Ross, MD, FRCP, of the University of Sheffield in the United Kingdom examined the relationship between testosterone levels, quality of life, self-esteem, fatigue and sexual function in 176 young male cancer survivors compared with 213 young men without cancer.

Young male cancer survivors said they experienced a marked impairment in quality of life, as well as reduced energy levels and quality of sexual function. These experiences were exacerbated in survivors with testosterone deficiency. Psychological distress was not elevated, self-esteem was normal, and sexual relationships were not impaired in male cancer survivors, however.

Professor Ross commented: "This is an important study demonstrating that low testosterone levels are common in male cancer survivors and associated with an impaired quality of life. However, the relationship between testosterone levels and quality of life is complex and appears to depend on a threshold level rather than on a direct correlation. We now need interventional trials with testosterone to determine which young male cancer survivors will benefit from replacement therapy."


Story Source:

The above story is based on materials provided by American Cancer Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Greenfield et al. Quality of life, self-esteem, fatigue, and sexual function in young men after cancer A controlled cross-sectional study. Cancer, 2010 DOI: 10.1002/cncr.24898

Cite This Page:

American Cancer Society. "Testosterone deficiency affects male cancer survivors' quality of life." ScienceDaily. ScienceDaily, 22 February 2010. <www.sciencedaily.com/releases/2010/02/100222081917.htm>.
American Cancer Society. (2010, February 22). Testosterone deficiency affects male cancer survivors' quality of life. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2010/02/100222081917.htm
American Cancer Society. "Testosterone deficiency affects male cancer survivors' quality of life." ScienceDaily. www.sciencedaily.com/releases/2010/02/100222081917.htm (accessed October 30, 2014).

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