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Mouse Model Would Have Predicted Toxicity of Drug That Killed 5 in 1993 Clinical Trial
Apr. 15, 2014 — Over 20 years after the fatal fialuridine trial, a new study demonstrates that mice with humanized livers recapitulate the drug's toxicity. The work suggests that this mouse model should be ... full story -
Breaking Bad Mitochondria: How Hepatitis C Survives for So Long
Apr. 15, 2014 — A mechanism has been discovered that explains why people with the hepatitis C virus get liver disease and why the virus is able to persist in the body for so long. The hard-to-kill pathogen, which ... full story -
Mechanism, Possible Treatment, for Immune Suppression in Liver Disease Uncovered
Apr. 13, 2014 — The mechanism that underlies the susceptibility of liver disease patients to life-threatening infection has been uncovered by medical scientists, who have also suggested a possible treatment to ... full story -
Hepatitis C Treatment Cures Over 90 Percent of Patients Who Also Have Cirrhosis
Apr. 12, 2014 — Twelve weeks of an investigational oral therapy cured hepatitis C infection in more than 90 percent of patients with liver cirrhosis and was well tolerated by these patients, according to a new ... full story -
Low Vitamin D Linked to Fatty Liver Disease in UK Children
Apr. 12, 2014 — A UK study investigating the link between low vitamin D status and non-alcoholic fatty liver disease in British children has identified a genetic variant associated with the disease's ... full story -
Fecal Transplant? Gut Microbiota May Play a Role in Development of Alcoholic Liver Disease
Apr. 12, 2014 — Exciting new data shows that the gut microbiota has a potential role in the development of alcoholic liver disease. Though an early stage animal model, a French study highlights the possibility of ... full story -
Impressive SVR12 Data for Once-Daily Combination to Treat HCV Genotype 1 Patients
Apr. 12, 2014 — Results from three Phase III clinical trials evaluating the investigational once-daily fixed-dose combination of the nucleotide analogue polymerase inhibitor sofosbuvir 400mg and the NS5A inhibitor ... full story -
New Chinese Herbal Medicine Has Significant Potential in Treating Hepatitis C, Study Suggests
Apr. 12, 2014 — A new compound, SBEL1, has the ability to inhibit hepatitis C virus activity in cells at several points in the virus' lifecycle. SBEL1 is a compound isolated from Chinese herbal medicines that ... full story -
Immunotherapy Could Help Tackle Tough Liver Cancer
Apr. 11, 2014 — Significant new data indicate that liver cancer may be treated by adoptive T cell therapy. This new therapeutic approach in the treatment of HCC could be very important as without treatment the 5 ... full story -
Positive Outcomes for Hepatitis C Transplant Patients
Apr. 11, 2014 — There is new hope for the notoriously difficult-to-treat population of liver transplant patients with recurring hepatitis C, researchers have announced. Hepatitis C infection is a common cause of ... full story -
Unexpected Results in Cancer Drug Trial: Combination of Cetuximab, Chemo Had Negative Results
Apr. 8, 2014 — A drug, used in combination with chemotherapy to treat advanced colorectal cancer, is not effective in some settings, and indeed may result in more rapid cancer progression, research has shown. The ... full story -
Ultrathin Collagen Matrix Biomaterial Tool for 3-D Microtissue Engineering
Apr. 3, 2014 — A novel ultrathin collagen matrix assembly allows for the unprecedented maintenance of liver cell morphology and function in a microscale 'organ-on-a-chip' device that is one example of 3D ... full story -
Coffee Consumption Reduces Mortality Risk from Liver Cirrhosis
Apr. 2, 2014 — Consuming two or more cups of coffee each day reduces the risk of death from liver cirrhosis by 66%, specifically cirrhosis caused by non-viral hepatitis, new research reveals. Findings show that ... full story -
Screening for Liver Cancer in Patients With Cirrhosis
Apr. 1, 2014 — In a systematic review and meta-analysis of 47 studies with 15,158 patients, medical researchers found that patients with cirrhosis who underwent surveillance, via liver ultrasound with or without ... full story -
Low Sodium Levels Pre-Transplant Does Not Affect Liver Transplant Recipient Survival
Apr. 1, 2014 — Low levels of sodium, known as hyponatremia, prior to transplantation does not increase the risk of death following liver transplant. Medical evidence shows that low sodium concentration is common in ... full story -
Y-90 Provides New, Safe Treatment for Metastatic Breast Cancer
Mar. 24, 2014 — A minimally invasive treatment that delivers cancer-killing radiation directly to tumors shows promise in treating breast cancer that has spread to the liver when no other treatment options remain. ... full story -
Hepatitis C Remains Major Problem for HIV Patients Despite Antiretroviral Therapy
Mar. 17, 2014 — The risk of hepatitis C-associated serious liver disease persists in HIV patients otherwise benefiting from antiretroviral therapy (ART) to treat HIV, a study has found. It has been suggested that ... full story -
Gene Variants Protect Against Relapse After Treatment for Hepatitis C
Mar. 13, 2014 — Researchers have identified a gene that helps to explain why certain patients with chronic hepatitis C do not experience relapse after treatment. The discovery may contribute to more effective ... full story -
Liver Transplant May Arrest Neurological Damage in Rare, Progressive Form of Autism
Mar. 12, 2014 — A patient with a rare metabolic disease, lathosterolosis, that causes liver failure and autistic behavior experienced significant improvements in both her physical and mental health after receiving a ... full story -
New Hepatitis C Drugs Offer Hope for Effective Treatment, Fewer Side Effects
Mar. 11, 2014 — She had heard the horror stories about early treatments for hepatitis C -- multiple daily pills and weekly shots for up to a year, side effects that could be debilitating, and a cure rate of only ... full story
- Mouse model would have predicted toxicity of drug that killed 5 in 1993 clinical trial
- Breaking bad mitochondria: How hepatitis C survives for so long
- Hepatitis C treatment cures over 90 percent of patients who also have cirrhosis
- Low vitamin D linked to fatty liver disease in UK children
- Fecal transplant? Gut microbiota may play a role in development of alcoholic liver disease
- Impressive SVR12 data for once-daily combination to treat HCV genotype 1 patients
- New Chinese herbal medicine has significant potential in treating hepatitis C, study suggests
- Immunotherapy could help tackle tough liver cancer
- Positive outcomes for hepatitis C transplant patients
- Screening for liver cancer in patients with cirrhosis
- Low sodium levels pre-transplant does not affect liver transplant recipient survival
- Scientists find cell fate switch that decides liver, or pancreas?
- Muscle loss ups mortality, sepsis risk in liver transplant candidates
- More benefits emerging for one type of omega-3 fatty acid: DHA
- Morbidity higher in obese liver transplant recipients with diabetes, survival not impacted
- New study reveals links between alcoholic liver disease, circadian clock
- New proposal for better allocation of donated livers in transplants
- New drug combo cures toughest cases of hepatitis C, hints to future injection-free therapies
- Monitoring inactive hepatitis B patients is cost-effective strategy
- Genetic flaw in males triggers onset of liver cancer, diabetes
- Revised clinical practice guidelines to optimize management of hepatitis C
- Transcription factor may protect against hepatic injury caused by hepatitis C, alcohol
- Could deceased heart attack victims expand donor pool?
- Fast, painless alternative to liver biopsie proves accurate, reliable
- Experimental hepatitis C drug shows promise for preventing recurrence in liver transplant patients
- Effects of liver regenerating protein discovered
- Coffee consumption reduces risk of liver cancer, analysis suggests
- Milk-maker hormone may help liver regenerate
- World first: Lungs awaiting transplant preserved 11 hours outside body
- Kidney failure can complicate long-term outcomes in children receiving solid-organ transplants
- Herbal, weight loss supplements, energy drink associated with liver damage, liver failure
- Researchers identify liver cancer progenitor cells before tumors become visible
- New hepatitis C drug shows potential in phase 2 trials
- Likely culprit behind liver problems linked to intravenous feeding
- Neurological researchers find fat may be linked to memory loss
- Renal risk index: Clinical tool to predict risk of end-stage renal disease
- Genes associated with unhealthy liver function
- Combination therapy for severe alcoholic hepatitis does not result in improved survival
- Researchers link obesity and the body's production of fructose
- Stem cells reach standard for use in drug development
- Partial livers from deceased donors saving the lives of infants
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