Featured Research

from universities, journals, and other organizations

Mathematical models for breast cancer detection with microwave tomography are cheaper and less risky, research finds

Date:
July 12, 2010
Source:
Society for Industrial and Applied Mathematics
Summary:
The most popular method of breast cancer detection today is X-ray mammography, which takes images of a compressed breast by low-dose ionizing radiation. However, there are several disadvantages to using X-rays for breast cancer screening, chief among them being the invasiveness of radiation and the high costs. Microwave tomography can provide a cheaper and less risky alternative to X-ray mammography, according to new research.

The most popular method of breast cancer detection today is X-ray mammography, which takes images of a compressed breast by low-dose ionizing radiation. However, there are several disadvantages to using X-rays for breast cancer screening, chief among them being the invasivity of radiation and the high costs, which limit their wide use and can deter women from getting them. In addition, depending on the age of the patient and tissue density, X-ray mammograms often result in false positives and negatives.

Related Articles


Microwave tomography can provide a cheaper and less risky alternative to X-ray mammography. In a paper published in the SIAM Journal on Applied Mathematics, the authors describe a mathematical model for imaging tumors in the breast using microwave tomography. Microwave tomography detects cancers by measuring inhomogeneities in the electrical conductivity of breast tissue. An array of low-power microwaves are transmitted into the breast from different positions and the resulting scattered signals are collected by antennas surrounding it. The malignant-to-normal tissue contrast arises because cancerous cells have higher water content, and are hence stronger scatterers than normal tissue.

The electrical properties measured by microwaves are sensitive to physiological parameters such as water content, temperature and vascularization. In addition, they can give an estimate of mammographic breast density, which is a crucial factor in evaluating a patient's risk of breast cancer. The distribution of these electrical parameters in space is used to reconstruct the image of the breast with the help of carefully designed algorithms.

There is room for improvement in the mathematical method that currently exists for image reconstruction in microwave tomography. The problem to be solved is an inverse scattering problem. At microwave frequencies, the inverse problem is difficult to solve accurately because it is highly nonlinear. In addition, it is an ill-posed problem, which means that it does not have a solution in the strict sense, the solutions are not usually unique, and may not depend continuously on the data.

Different approaches have been used to circumvent these. One involves linearizing the problem, but this can result in significant loss of accuracy. A second approach uses nonlinear optimization and relies on initial apriori information on object shape and electric properties. While this yields more accurate results, its reliability depends on the accuracy of the initial information and is computationally expensive.

A more recent approach uses a qualitative method utilizing "sets" of linear integral equations of the first kind. While these are faster and don't require apriori information, they can only provide estimates for sets of points. In this paper, the authors use a linear sampling method in combination with a gap functional to take into account near fields instead of far fields. This results in higher accuracy.


Story Source:

The above story is based on materials provided by Society for Industrial and Applied Mathematics. Note: Materials may be edited for content and length.


Journal Reference:

  1. F. Delbary, M. Brignone, G. Bozza, R. Aramini, and M. Piana. A Visualization Method for Breast Cancer Detection Using Microwaves. SIAM J. Appl. Math., Volume 70, Issue 7, pp. 2509-2533; July 6, 2010 DOI: 10.1137/090774720

Cite This Page:

Society for Industrial and Applied Mathematics. "Mathematical models for breast cancer detection with microwave tomography are cheaper and less risky, research finds." ScienceDaily. ScienceDaily, 12 July 2010. <www.sciencedaily.com/releases/2010/07/100707091209.htm>.
Society for Industrial and Applied Mathematics. (2010, July 12). Mathematical models for breast cancer detection with microwave tomography are cheaper and less risky, research finds. ScienceDaily. Retrieved January 29, 2015 from www.sciencedaily.com/releases/2010/07/100707091209.htm
Society for Industrial and Applied Mathematics. "Mathematical models for breast cancer detection with microwave tomography are cheaper and less risky, research finds." ScienceDaily. www.sciencedaily.com/releases/2010/07/100707091209.htm (accessed January 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, January 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Malnutrition on the Rise as Violence Flares in C. Africa

Malnutrition on the Rise as Violence Flares in C. Africa

AFP (Jan. 28, 2015) Violence can flare up at any moment in Bambari with only a bridge separating Muslims and Christians. Malnutrition is on the rise and lack of water means simple cooking fires threaten to destroy makeshift camps where people are living. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Poultry Culled in Taiwan to Thwart Bird Flu

Poultry Culled in Taiwan to Thwart Bird Flu

Reuters - News Video Online (Jan. 28, 2015) Taiwan culls over a million poultry in efforts to halt various strains of avian flu. Julie Noce reports. Video provided by Reuters
Powered by NewsLook.com
Media Criticizing Parents For Not Vaccinating Children

Media Criticizing Parents For Not Vaccinating Children

Newsy (Jan. 28, 2015) As the Disneyland measles outbreak continues to spread, the media says parents who choose not to vaccinate their children are part of the cause. Video provided by Newsy
Powered by NewsLook.com
Shark Bite Victim Making Amazing Recovery

Shark Bite Victim Making Amazing Recovery

AP (Jan. 27, 2015) A Texas woman who lost more than five pounds of flesh to a shark in the Bahamas earlier this month could be released from a Florida hospital soon. Experts believe she was bitten by a bull shark while snorkeling. (Jan. 27) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins