Featured Research

from universities, journals, and other organizations

Burden of antibiotic resistance in Europe

Date:
October 11, 2011
Source:
Public Library of Science
Summary:
Hospital associated infections (HAI) are often in the headlines, but what is the burden of mortality, morbidity and costs due to HAIs? Researchers now report the results of a prospective clinical investigation into the societal burden of HAIs from 31 European countries.

Hospital associated infections (HAI) are often in the headlines, but what is the burden of mortality, morbidity and costs due to HAIs? In this week's PLoS Medicine, Marlieke de Kraker, Peter Davey and Hajo Grundmann, on behalf of the BURDEN (Burden of resistance and disease in European nations) study group, report the results of a prospective clinical investigation into the societal burden of HAIs from 31 European countries.

The researchers combined prospective data on the burden of methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli bloodstream infections with 2007 prevalence data from the European Antibiotic Resistance Surveillance System (EARSS) to calculate excess mortality, excess hospital stay, and hospital expenditure.

Data from 1293 hospitals in 31 countries revealed that an estimated 5,503 excess deaths were associated with bloodstream infections caused by MRSA (with the UK and France predicted to experience the highest excess mortality) and 2,712 excess deaths from bloodstream infections caused by third-generation cephalosporin-resistant E. coli (predicted to be the highest in Turkey and the UK). The researchers also found that bloodstream infections caused by MRSA and third-generation cephalosporin-resistant E. coli contributed an excess of 255,683 and 120,065 extra bed-days respectively. This translated to an estimated extra cost of 62.0 million Euros (92.8 million international dollars) attributable to these infections.

By looking at trends in their analyses they also estimate that 97,000 resistant bloodstream infections and 17,000 associated deaths could occur in 2015, with associated increases in hospital stay and costs. They finish by saying that 'Forecasts about changes in the coming years are disturbing; despite anticipated gains in the control of MRSA, the persistently increasing number of infections caused by third-generation cephalosporin-resistant Gram-negative pathogens is likely to outweigh this achievement soon.'

This work was funded by DG-Sanco (grant number 2005203), University Medical Centre Groningen, and the Netherlands National Institute for Public Health and the Environment.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Marlieke E. A. de Kraker, Peter G. Davey, Hajo Grundmann. Mortality and Hospital Stay Associated with Resistant Staphylococcus aureus and Escherichia coli Bacteremia: Estimating the Burden of Antibiotic Resistance in Europe. PLoS Medicine, 2011; 8 (10): e1001104 DOI: 10.1371/journal.pmed.1001104

Cite This Page:

Public Library of Science. "Burden of antibiotic resistance in Europe." ScienceDaily. ScienceDaily, 11 October 2011. <www.sciencedaily.com/releases/2011/10/111011171544.htm>.
Public Library of Science. (2011, October 11). Burden of antibiotic resistance in Europe. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2011/10/111011171544.htm
Public Library of Science. "Burden of antibiotic resistance in Europe." ScienceDaily. www.sciencedaily.com/releases/2011/10/111011171544.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins