Featured Research

from universities, journals, and other organizations

Role of fat in assessing breast cancer risk

Date:
December 8, 2011
Source:
BioMed Central
Summary:
It is known that a high proportion of dense breast tissue, as seen with a mammogram, is associated with a high risk of breast cancer. But the role of non-dense fat tissue in the breast is less clear. New research separates the breast cancer risks associated with dense, fibroglandular tissue, and fat, and shows that large areas of either are independently associated with an increased risk.

It is known that a high proportion of dense breast tissue, as seen with a mammogram, is associated with a high risk of breast cancer. But the role of non-dense fat tissue in the breast is less clear. New research published in BioMed Central's open access journal Breast Cancer Research separates the breast cancer risks associated with dense, fibroglandular tissue, and fat, and shows that large areas of either are independently associated with an increased risk.

Related Articles


The mammograms of postmenopausal women with breast cancer were compared to controls without cancer. The study used sophisticated computer software to read the films to reduce reader error (or intuition). The software simply compared dense versus non-dense tissue and was not looking for specific irregularities.

Not surprisingly older women and women with a higher BMI have a higher percentage of non-dense tissue. The women with breast cancer tended to have a larger area of dense tissue and a larger area of non-dense tissue so that the biggest risk was for women with the largest areas of both. However this is not necessarily reflected in breast size because the risk associated with fat, though significant, is lower than the risk associated with fibroglandular tissue. Consequently women with a smaller amount of dense tissue have a lower risk than those with more dense tissue for the same breast size.

Dr Carla van Gils, from the University Medical Centre Utrecht, who lead the research explained, "Fat tissue is known to produce the hormones such as oestrogen which are known to promote the growth of ER positive cancer. However it seems that it is the local fat tissue which is important to breast cancer risk at not just general body fat (as measured using BMI). Consequently it may be important to consider both types of tissue when assessing breast cancer risk."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mariëtte Lokate, Petra H.M. Peeters, Linda M. Peelen, Gerco Haars, Wouter B. Veldhuis and Carla H. van Gils. Mammographic density and breast cancer risk: the role of the fat surrounding the fibroglandular tissue. Breast Cancer Research, 2011; (in press) [link]

Cite This Page:

BioMed Central. "Role of fat in assessing breast cancer risk." ScienceDaily. ScienceDaily, 8 December 2011. <www.sciencedaily.com/releases/2011/10/111025210910.htm>.
BioMed Central. (2011, December 8). Role of fat in assessing breast cancer risk. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2011/10/111025210910.htm
BioMed Central. "Role of fat in assessing breast cancer risk." ScienceDaily. www.sciencedaily.com/releases/2011/10/111025210910.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) — Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) — Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) — AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com
Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) — Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins