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Nanofibrillar cellulose film to ease performing medical tests

Date:
October 23, 2012
Source:
Aalto University
Summary:
Researchers have succeeded in developing a durable and affordable nanofibrillar cellulose film platform to support medical testing. New environmentally friendly, reliable nanofibrillar cellulose (NFC) platforms are more diverse than plastic films. New film can be made, for instance, hydrophobic, hydrophilic and the electric charge can be changed. This will enhance the possibility of conducting thousands of different medical tests at home or in physicians’ receptions instead of waiting for results from laboratories.

New nanofibrillar cellulose film platforms are durable and affordable.
Credit: Image courtesy of Aalto University

Researchers at Aalto University in Finland have succeeded in developing a durable and affordable nanofibrillar cellulose film platform to support medical testing. New environmentally friendly, reliable nanofibrillar cellulose (NFC) platforms are more diverse than plastic films. New film can be made, for instance, hydrophobic, hydrophilic and the electric charge can be changed. This will enhance the possibility of conducting thousands of different medical tests at home or in physicians' receptions instead of waiting for results from laboratories.

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A platform is coated with the new film in the factory. The film is injected with substances that will react to the tested substance. At the place of testing, blood, water or another test material will be applied on to the film. The antibody injected onto the film will absorb the sample, depending on whether it contains substances causing allergic reactions, or bacteria, for example. Then the test result is visualised with the help of colour‑changing chemistry, for example.

"Thanks to the new film, various tests can be conducted faster without compromising reliability. It will now be easier to detect microbes that cause illnesses in the physician's reception, or to monitor allergens at home. In addition to medical diagnostics, the film can be utilised to study water purity, for example," says doctoral candidate Hannes Orelma at Aalto University.

Previous attempts to produce a nanofibrillar cellulose platform have failed when the porous plate absorbed part of the sample. Now researchers have developed a method of producing a water‑proof nanofibrillar cellulose gel that will not absorb samples. They have also made great efforts to ensure sufficient film durability.


Story Source:

The above story is based on materials provided by Aalto University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hannes Orelma, Ilari Filpponen, Leena-Sisko Johansson, Monika Φsterberg, Orlando J. Rojas, Janne Laine. Surface Functionalized Nanofibrillar Cellulose (NFC) Film as a Platform for Immunoassays and Diagnostics. Biointerphases, 2012; 7 (1-4) DOI: 10.1007/s13758-012-0061-7

Cite This Page:

Aalto University. "Nanofibrillar cellulose film to ease performing medical tests." ScienceDaily. ScienceDaily, 23 October 2012. <www.sciencedaily.com/releases/2012/10/121023112356.htm>.
Aalto University. (2012, October 23). Nanofibrillar cellulose film to ease performing medical tests. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2012/10/121023112356.htm
Aalto University. "Nanofibrillar cellulose film to ease performing medical tests." ScienceDaily. www.sciencedaily.com/releases/2012/10/121023112356.htm (accessed October 31, 2014).

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