Personalized Medicine News
July 30, 2015

Latest Headlines
updated 10:30am EDT

More Personalized Medicine News
July 30, 2015

Race, Institutional Factors Play an Important Role in Pharmacogenomic Trial Participation

July 28, 2015 — The participation rate of patients in pharmacogenomic trials has been the focus of recent study. The research has concluded that there are a number of factors at the patient, physician, institution ... read more

Clinical Validation for LOXO-101 Against TRK Fusion Cancer

July 27, 2015 — The first imaging studies of TRK fusion cancer conducted post-treatment have confirmed that stage IV patient's tumors had substantially regressed. With four months of treatment, additional CT ... read more

Liquid Biopsy Identifies Mutations in Colorectal Cancer Undetected in Tissue Biopsy

July 13, 2015 — The CORRECT study is one of the largest trials to date comparing data provided by liquid versus tissue biopsy in metastatic colorectal cancer patients. According to the study, liquid biopsy (BEAMing ... read more

Study Advances Potential of Tumor Genome Sequencing and DNA-Based Blood Tests in Precision Treatment

July 9, 2015 — In a genome-sequencing study of pancreatic cancers and blood in 101 patients, scientists say they found at least one-third of the patients' tumors have genetic mutations that may someday help ... read more

Scientists Lead Consensus Guidelines for Thyroid Cancer Molecular Tests

July 6, 2015 — National guidelines for thyroid cancer testing have been revised to reflect newly available tests that better incorporate personalized medicine into diagnosing the condition. The clinical explanation ... read more

Discovery Could Lead to Personalized Colon Cancer Treatment Approach

June 29, 2015 — Researchers report their findings of just how a certain tumor-suppressing protein helps prevent colon cancer. With this discovery, researchers believe they’ve found a possible drug target for colon ... read more

Analyzing Genes According to Evolutionary Profile

June 25, 2015 — Scientists have developed a new Internet tool that will allow any investigator, physician or patient to analyze genes according to their evolutionary profile and find associated genes. The tool ... read more

E2F4 Signature Can Predict Progression of Bladder Cancer

June 25, 2015 — Investigators harnessed genomic data to discover that the previously identified E2F4 signature in breast cancer can be utilized to predict prognosis and response to therapy in bladder ... read more

Future Physicians More Inclined to Embrace Genomic Medicine Than Practicing Physicians

June 24, 2015 — Medical students showed a greater acceptance of using approaches in genomic medicine, a key element in the practice of precision medicine, to treat patients as compared to physicians currently in ... read more

Mapping Genetic Mutations in Skin Cancer

June 18, 2015 — A study by The Cancer Genome Atlas network of researchers refined and revealed molecular sub-groups of patients with cutaneous melanoma who could potentially benefit from targeted treatments based on ... read more

Genomic Discovery of Skin Cancer Subtypes Provides Potential 'Signpost' for Drug Targets

June 18, 2015 — Cutaneous melanoma, the most deadly form of skin cancer, is now believed to be divided into four distinct genomic subtypes, say researchers, a finding that could prove valuable in the ever-increasing ... read more

Scientists Find Genetic Variants Key to Understanding Origins of Ovarian Cancer

June 15, 2015 — New research is bringing the origins of ovarian cancer into sharper focus.The study highlights the discovery of three genetic variants associated with mucinous ovarian carcinomas (MOCs), offering the ... read more

June 11, 2015 — The rise of health apps has made it possible to chart your steps, heartbeat, and sleep patterns, but the availability of this constant stream of information has yet to reach patient electronic health ... read more

Establishing Definitions to Increase Survival After Blood/marrow Transplant

June 9, 2015 — Blood and Marrow Transplantation (BMT) is a potentially curative treatment for patients with leukemia or other life-threating blood diseases. With a goal of increasing survival rates, a research team ... read more

June 8, 2015 — A new approach for studying the cancer genome has been described by researchers who say that it will let scientists account for both the individual tiles and the whole mosaic. It enables researchers ... read more

Theranostic PET Takes on Both Ovarian and Prostate Cancer

June 8, 2015 — A first-in-human study shows how a powerful new drug finds and attaches itself to the ovarian and prostate cancer cells for both imaging and personalized cancer ... read more

Researchers Develop Models for Targeted Cancer Therapy

June 8, 2015 — The results of a recent study on targeted therapy of a specific type of brain cancer show specific progress in cancer treatment. Diffuse intrinsic pontine glioma may be one of the lesser-known forms ... read more

Available Genetic Data Could Help Doctors Make Better Use of Cardiovascular Drugs

June 1, 2015 — Few heart specialists make use of published information about interactions between drugs used to treat cardiovascular disease and the genetic variations that affect how patients respond to them, ... read more

Researcher Discovers Metabolite of Prostate Cancer Drug More Effective at Treating Aggressive Tumors

June 1, 2015 — A metabolite of an FDA-approved drug for metastatic prostate cancer, abiraterone, has more anti-cancer properties than its precursor, researchers have discovered for the first time. Prostate cancer ... read more

Possible New Combination Chemotherapy for Patients With Advanced Prostate Cancer

May 31, 2015 — A role for combination therapy using two or more chemotherapy agents at the same time has not been well studied. This week, however, results of a clinical trial may change the perspective on a role ... read more

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