Pharmacology News
September 4, 2015

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September 4, 2015

Inexpensive Drug Saves Blood and Money, Study Shows

Sep. 4, 2015 — Using an inexpensive drug for every hip or knee replacement has helped one hospital reduce its number of red blood cell transfusions performed during these surgeries by more than 40 percent without ... read more

Rapid Testing for TB Aims to Reduce Drug Resistance, Lower Mortality Rate

Sep. 3, 2015 — Researchers have documented the accuracies of three new tests for more rapidly diagnosing drug-resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, ... read more

Drug for Fungal Infections in Lung Transplant Recipients Increases Risk for Cancer, Death

Sep. 3, 2015 — Voriconazole, a prescription drug commonly used to treat fungal infections in lung transplant recipients, significantly increases the risk for skin cancer and even death, according to a new ... read more

Needle Exchange Program Prevented 120 New Cases of HIV in Two Years, Study Suggests

Sep. 3, 2015 — The District of Columbia's needle exchange program prevented 120 new cases of HIV infection and saved an estimated $44 million over just a two-year period, according to a first-of-a-kind ... read more

Long-Term Study Links Common Psychiatric Disorders With Increased Risk of Violent Reoffending in Ex-Prisoners

Sep. 2, 2015 — Ex-prisoners with common psychiatric disorders such as bipolar disorder (manic-depressive disorder) and alcohol and drug abuse are substantially more likely to commit a violent crime after release ... read more

Sep. 2, 2015 — New research may help explain why drug treatments for addiction and depression don't work for some patients. The conditions are linked to reward and aversion responses in the brain. And the ... read more

Telomerase Targeting Drug Demonstrates Benefit in Myelofibrosis Treatment

Sep. 2, 2015 — Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a new ... read more

Cellular Recycling Complexes May Hold Key to Chemotherapy Resistance

Sep. 2, 2015 — Upsetting the balance between protein synthesis, misfolding, and degradation drives cancer and neurodegeneration. Recent cancer treatments take advantage of this knowledge with a class of drugs that ... read more

Sep. 2, 2015 — Bacteria's ability to become resistant to antibiotics is a growing issue in health care: Resistant strains result in prolonged illnesses and higher mortality rates. One way to combat this is to ... read more

Common Diabetes Drug Could Be Used to Prevent Hemorrhage, Fatal Blood Loss

Sep. 1, 2015 — Massive blood loss often leads to death, and when blood transfusions are unavailable, drugs are currently being tested that can keep people alive until they get to hospital. Understanding how these ... read more

Antipsychotics Inappropriately Prescribed to People With Intellectual Disabilities

Sep. 1, 2015 — Large numbers of people with intellectual disabilities in the UK are being inappropriately prescribed antipsychotic drugs, finds a new study. Intellectual disability is a lifelong condition that ... read more

Sep. 1, 2015 — New technology that transforms a cell phone into a powerful, mobile microscope could significantly improve malaria diagnoses and treatment in developing countries that often lack the resources to ... read more

When Stroke Patients Undergo Surgery to Remove Blood Clots, What Anesthesia Works Best?

Sep. 1, 2015 — As more stroke patients undergo minimally invasive procedures to stop strokes in progress, physicians are debating the best way to anesthetize patients -- general anesthesia or conscious ... read more

Researchers Develop a Likely New Combo Treatment for the Deadliest Form of Brain Cancer

Sep. 1, 2015 — Scientists have developed a potentially promising new combination therapy for glioblastoma, the deadliest form of brain cancer. Glioblastoma, also known as grade IV glioma, is the most aggressive ... read more

Another Way Urate May Protect Against Parkinson's Disease

Sep. 1, 2015 — A study from members of the research team investigating whether increasing blood levels of the antioxidant urate can slow the progression of Parkinson's disease has found that the ... read more

Sep. 1, 2015 — Statins are a popular and easy-to-swallow option for people looking to lower their cholesterol. But for a quarter of patients, statins come with muscle pain, stiffness, cramps, or weakness without ... read more

Medication Improves Measure of Kidney Disease in Patients With Diabetes

Sep. 1, 2015 — Among patients with diabetes and kidney disease, most receiving an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker, the addition of the medication finerenone compared with ... read more

Which Blood Thinner Works Better During Stent Placement? It's Still a Toss-Up

Sep. 1, 2015 — A large, ambitious contrast of blood-thinning medications used during cardiac stent placement suggests that a very expensive drug offers no clear safety benefits over a much more affordable option, ... read more

Daily Marijuana Use Among U.S. College Students Highest Since 1980

Sep. 1, 2015 — Daily marijuana use among the nation's college students is on the rise, surpassing daily cigarette smoking for the first time in ... read more

Injection Drug Use Limits Benefits of Surgery for Treatment of Heart Lining Infection

Sep. 1, 2015 — Injection drug users who undergo surgery for infective endocarditis (IE) have a significantly higher risk of reoperation or death between 3 and 6 months after surgery compared to patients who develop ... read more

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