Pharmacology News
February 8, 2016

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updated 5:00am EST

More Pharmacology News
February 8, 2016

Feb. 5, 2016 — First-ever interlaboratory study of four versions of a therapeutic protein drug -- all manufactured from living cells -- reports that an established analytical tool akin to magnetic resonance imaging ... read more

Single-Lesion Biopsy May Be Insufficient to Choose Therapy Targeting Resistance Mutations

Feb. 5, 2016 — When metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug, the usual practice is to test a single metastatic lesion for new mutations that can ... read more

New Method for Rapid Detection of Infection in Wounds

Feb. 5, 2016 — A new method for detection of infection in wounds could take physicians less than a minute to complete, rather than the current 24 hours it takes for ... read more

Feb. 4, 2016 — Using a special profiling technique, researchers have determined the mechanism of action of a potent antibiotic, known as tropodithietic acid, leading them to uncover its hidden ability as a ... read more

Feb. 4, 2016 — In a new study, researchers show that a particular protein found in the brains of both male and female mice is present at higher levels in females, which offers them stronger protection against one ... read more

C. Diff Study Provides Insight Into Antibiotic Resistance and Risks for Infection

Feb. 4, 2016 — Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new ... read more

Dogs Accelerate the Advance of New Cancer Treatments for Both Pets and People

Feb. 4, 2016 — A new review suggests integrating dogs with naturally occurring cancers into studies of new drug therapeutics could result in better treatments for our four-legged friends while helping inform ... read more

Functional MRI May Help Identify New, Effective Painkillers for Chronic Pain Sufferers

Feb. 4, 2016 — New research may allow new, more effective and safer pain medications to reach patients who suffer from chronic pain ... read more

Using Steroids Before Late Preterm Delivery Reduces Neonatal Respiratory Problems

Feb. 4, 2016 — Using corticosteroids in mothers at risk for late preterm delivery reduced the incidence of severe respiratory complications in their babies, new research indicates. The new study enrolled more than ... read more

For Pregnant Women With Flu, the Earlier the Better for Antiviral Treatment

Feb. 4, 2016 — Pregnant women are at higher risk for serious illness and complications, including death, from influenza. For expectant mothers hospitalized with flu, early treatment with the influenza antiviral ... read more

Improvised Naloxone Nasal Sprays Lack Evidence of Absorption and Effect

Feb. 4, 2016 — Naloxone hydrochloride is a medication that can reverse the effects of an opioid overdose. Recently, the US Food and Drug Administration (FDA) approved a nasal naloxone product to replace those ... read more

Feb. 4, 2016 — Scientists have captured atomic images of the virus that causes cold sores in action. Structural details reveal that the virus inserts itself into another protein, jamming an important immune system ... read more

Investigation Casts Doubt Over Trial Used to Support Top-Selling Anti-Clotting Drug

Feb. 4, 2016 — An investigation raises new concerns about the top-selling anti-clotting drug, rivaroxaban (Xarelto). The trial compared rivaroxaban with the older anti-clotting drug warfarin for preventing strokes ... read more

Feb. 3, 2016 — The greedy metabolism of cancer cells to target kidney cell carcinomas, which kill more than 100,000 Americans each year, has been exploited by researchers. The team showed that the majority of renal ... read more

Model Helps Decide Drug Dose for Clinical Testing

Feb. 3, 2016 — A mathematical model may offer a valuable tool for selecting the proper dose of antiviral drugs for further testing in clinical ... read more

New Insights Into the Function of the Main Class of Drug Targets

Feb. 3, 2016 — About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors. Researchers has now ... read more

What's the Impact of New Marijuana Laws? The Data So Far

Feb. 3, 2016 — How has new legislation affected marijuana use in the United States? The best available data suggest that marijuana use is increasing in adults but not teens, with a decrease in marijuana-related ... read more

Feb. 3, 2016 — For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds ... read more

Investigating Potential Fetal Exposure to Antidepressants

Feb. 3, 2016 — Depression is a serious issue for expecting mothers. Left untreated, depression could have implications for a fetus's health. But treating the disease during pregnancy may carry health risks for ... read more

Use of and Barriers to Access to Opioid Analgesics Worldwide

Feb. 3, 2016 — Use of common opioid painkillers such as codeine, morphine and oxycodone has more than quadrupled in Australia over the past decade and doubled worldwide over the same period. Yet at the same time ... read more

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