Pharmacology News
February 9, 2016

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updated 4:30am EST

More Pharmacology News
February 9, 2016

Feb. 5, 2016 — First-ever interlaboratory study of four versions of a therapeutic protein drug -- all manufactured from living cells -- reports that an established analytical tool akin to magnetic resonance imaging ... read more

Single-Lesion Biopsy May Be Insufficient to Choose Therapy Targeting Resistance Mutations

Feb. 5, 2016 — When metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug, the usual practice is to test a single metastatic lesion for new mutations that can ... read more

New Method for Rapid Detection of Infection in Wounds

Feb. 5, 2016 — A new method for detection of infection in wounds could take physicians less than a minute to complete, rather than the current 24 hours it takes for ... read more

New Assay Detects Persistent Disease in Leukemia Patients Thought to Be in Remission

Feb. 5, 2016 — A new study describes a new personalized DNA-based digital assay that detects persistent chronic myeloid leukemia in 81 percent of samples taken from a group of patients thought to be in ... read more

Feb. 4, 2016 — Using a special profiling technique, researchers have determined the mechanism of action of a potent antibiotic, known as tropodithietic acid, leading them to uncover its hidden ability as a ... read more

Better Quality of Care May Reduce Risk of Death for Patients on Opioid Painkillers

Feb. 4, 2016 — Better quality of care may reduce the risk of death for patients who are prescribed opioid painkillers for chronic pain, say Yale researchers. Their study offers evidence that supports ... read more

Feb. 4, 2016 — In a new study, researchers show that a particular protein found in the brains of both male and female mice is present at higher levels in females, which offers them stronger protection against one ... read more

C. Diff Study Provides Insight Into Antibiotic Resistance and Risks for Infection

Feb. 4, 2016 — Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new ... read more

Dogs Accelerate the Advance of New Cancer Treatments for Both Pets and People

Feb. 4, 2016 — A new review suggests integrating dogs with naturally occurring cancers into studies of new drug therapeutics could result in better treatments for our four-legged friends while helping inform ... read more

Patients With Macular Degeneration Show Improvement With High-Dose Statin Treatment

Feb. 4, 2016 — A phase I/II clinical trial has found that some patients taking high doses of atorvastatin (cholesterol-lowering medication) had complete resolution of lipid deposits in the dry form of age-related ... read more

Feb. 4, 2016 — Scientists have made an exciting discovery that could provide a new way to prevent bacterial infections in both humans and plants without triggering multi-drug resistance in ... read more

Feb. 4, 2016 — A new study reports that a new antiviral drug protects mice against a range of influenza virus strains. The compound seems to act superior to oseltamivir (Tamiflu) and independent of the host immune ... read more

Smart Contact Lens Helps Predict Disease Progression in Glaucoma Patients

Feb. 4, 2016 — A contact lens with a built-in sensor could help determine which glaucoma patients have a higher risk of disease progression, according to a new study. Researchers found certain patterns of ... read more

Functional MRI May Help Identify New, Effective Painkillers for Chronic Pain Sufferers

Feb. 4, 2016 — New research may allow new, more effective and safer pain medications to reach patients who suffer from chronic pain ... read more

Natural Protein Points to New Inflammation Treatment

Feb. 4, 2016 — Increasing the level of a naturally-produced protein, called tristetraprolin (TTP), significantly reduced or protected mice from inflammation, according to researchers. The results suggest that ... read more

Using Steroids Before Late Preterm Delivery Reduces Neonatal Respiratory Problems

Feb. 4, 2016 — Using corticosteroids in mothers at risk for late preterm delivery reduced the incidence of severe respiratory complications in their babies, new research indicates. The new study enrolled more than ... read more

For Pregnant Women With Flu, the Earlier the Better for Antiviral Treatment

Feb. 4, 2016 — Pregnant women are at higher risk for serious illness and complications, including death, from influenza. For expectant mothers hospitalized with flu, early treatment with the influenza antiviral ... read more

Improvised Naloxone Nasal Sprays Lack Evidence of Absorption and Effect

Feb. 4, 2016 — Naloxone hydrochloride is a medication that can reverse the effects of an opioid overdose. Recently, the US Food and Drug Administration (FDA) approved a nasal naloxone product to replace those ... read more

Feb. 4, 2016 — Scientists have captured atomic images of the virus that causes cold sores in action. Structural details reveal that the virus inserts itself into another protein, jamming an important immune system ... read more

Investigation Casts Doubt Over Trial Used to Support Top-Selling Anti-Clotting Drug

Feb. 4, 2016 — An investigation raises new concerns about the top-selling anti-clotting drug, rivaroxaban (Xarelto). The trial compared rivaroxaban with the older anti-clotting drug warfarin for preventing strokes ... read more

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