Pharmacology News
November 26, 2015

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November 26, 2015

New Gene Map Reveals Cancer's Achilles Heel

Nov. 25, 2015 — Scientists have mapped out the genes that keep our cells alive, creating a long-awaited foothold for understanding how our genome works and which genes are crucial in disease like ... read more

Researchers Assess Use of Drug-Susceptible Parasites to Fight Drug Resistance

Nov. 25, 2015 — A new model for evaluating a potential new strategy in the fight against drug-resistant diseases has been developed by experts. The strategy would take advantage of parasite refugia--host populations ... read more

Antibody-Drug Compounds and Immunotherapy to Treat Breast Cancer

Nov. 25, 2015 — To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years. ... read more

Anticancer Agent FL118 More Potent Than Its Analogs, Not Prone to Typical Channels of Resistance

Nov. 25, 2015 — A new synthetic form of camptothecin appears to have greater potency, longer efficacy and fewer adverse side effects than irinotecan and topotecan, report ... read more

Nov. 24, 2015 — A metal-free process has been developed for the rapid synthesis of elusive small-molecule catalysts that promise to speed the making of novel chemicals, including ... read more

Tuberculosis: Daily Antibiotics Recommended to Prevent Resistant Strains

Nov. 23, 2015 — A computer model of tuberculosis has shown that approved treatments prescribing antibiotic doses once or twice a week are more likely to lead to drug resistant strains than are daily antibiotic ... read more

Common Cause for Complications After Kidney Transplantation Identified

Nov. 23, 2015 — The BK polyomavirus often causes complications after kidney transplantation. A research group has now been able to show, that the immunosuppressive drug Tacrolimus directly activates the replication ... read more

Nov. 23, 2015 — The liver's cannabinoid receptors could be targeted to fight liver cancer in some patients, new research suggests. This work offers a way to predict what treatments have the best chance of ... read more

Pembrolizumab in Advanced Melanoma: Added Benefit for Certain Patients

Nov. 23, 2015 — Certain adults with pretreatment have fewer side effects under pembrolizumab. Treatment-naive patients without tumor mutation survive longer and have better social participation, report ... read more

Nov. 23, 2015 — A new technology that uses an oscillating electric field to easily and quickly isolate drug-delivery nanoparticles from blood has been developed by a team of engineers. The technology could serve as ... read more

Identification of Barrier That Prevents Progression of Benign Kidney Tumors to Malignant Disease

Nov. 20, 2015 — The inner workings of a rare benign kidney tumor has been studied. Researchers have now revealed a mechanism to prevent this type of tumor from becoming ... read more

Tumor-Suppressor P53 Regulates Protein That Stifles Immune Attack on Cancer

Nov. 20, 2015 — A crucial tumor-thwarting gene protects an immune attack against lung cancer by blocking the key to an off switch on T cells, the customized warriors of the immune system, a team of researchers ... read more

Nov. 20, 2015 — Fungi in the mucus of patients with cystic fibrosis has been examined by researchers who have discovered how one particularly cunning fungal species has evolved to defend itself against neighboring ... read more

Nov. 20, 2015 — A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow ... read more

Diabetes Drug Could Be Used to Combat Fatty Liver Disease, Research Shows

Nov. 19, 2015 — Findings from a new study present the possibility of new therapies for patients with non-alcoholic fatty liver disease, for which there is no current licensed treatment. The trial was the first of ... read more

Treatment for Sickle Cell Disease May Help Protect Patients' Kidney Function

Nov. 19, 2015 — After six months of treatment with hydroxyurea, sickle cell disease patients' kidney function, as measured by the urinary albumin/creatine ratio, improved significantly, report investigators at ... read more

Nov. 19, 2015 — This National Diabetes Month, there is some good news for people with eye complications from diabetes. A network of researchers has found that the drug Lucentis (ranibizumab) can be highly effective ... read more

Vision Test Gives Insight Into the Effect of Prenatal Exposure to Recreational Drugs

Nov. 19, 2015 — Children exposed to marijuana in the womb show a significant improvement in their ability to track moving objects at age four, according to new vision research. But researchers are warning that the ... read more

Nov. 19, 2015 — A new family of nanocarriers, called '3HM,' has been developed and meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment ... read more

'Orphan Drug' Loophole Needs Closing, Researchers Say

Nov. 19, 2015 — Health experts are calling on lawmakers and regulators to close loopholes in the Orphan Drug Act they claim give drug companies millions of dollars in unintended and misplaced subsidies and tax ... read more

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