Pharmacology News
August 30, 2015

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August 30, 2015

Probiotics Show No Impact Preventing Gastrointestinal Colonization With Drug-Resistant Bugs in ICU

Aug. 27, 2015 — Probiotics show no benefit for preventing or eliminating gastrointestinal colonization with drug-resistant organisms in patients in the intensive care unit compared to standard care, according to new ... read more

Health Workers Wasting Expensive Malaria Drugs in Nigeria

Aug. 27, 2015 — Health providers trained to perform malaria rapid diagnostic tests are still prescribing valuable malaria medicines to patients who do not have malaria, according to new ... read more

Exploding the Drug Deadlock: Repurposing Nitroglycerin for Anti-Cancer Treatments

Aug. 27, 2015 — For over a century, nitroglycerin has been used medically – particularly in the treatment of angina, or chest pain. It is a safe, cheap and effective treatment. Now, researchers have found that ... read more

CanDL Database Shines Light on Clinically Important Cancer Gene Mutations

Aug. 27, 2015 — To help molecular pathologists, laboratory directors, bioinformaticians and oncologists identify key mutations that drive tumor growth in tissues obtained during cancer clinical studies, researchers ... read more

Aug. 27, 2015 — Researchers have developed a dual catalyst system that directly installs alkyl groups -- fragments containing singly bonded carbon and hydrogen atoms that have extremely useful properties for drug ... read more

Immunotherapy Agent Benefits Patients With Drug-Resistant Multiple Myeloma

Aug. 26, 2015 — In its first clinical trial, a breakthrough antibody therapy produced at least partial remissions in a third of patients with multiple myeloma who had exhausted multiple prior treatments, ... read more

New Approach to Tackling Uncontrolled High Blood Pressure Shows Significant Results

Aug. 26, 2015 — Scientists have successfully improved blood pressure control among patients with severe intolerance to antihypertensive medication -- by using medicines in unconventional ways and treating patients ... read more

Aug. 26, 2015 — Compounds found in purple potatoes may help kill colon cancer stem cells and limit the spread of the cancer, according to a team of ... read more

Aug. 26, 2015 — Researchers say they have discovered some of the first steps in how a very common gene mutation causes the brain damage associated with both amyotrophic lateral sclerosis (ALS) and frontotemporal ... read more

Cannabis and the Brain

Aug. 26, 2015 — Two new studies examine associations between cannabis use and the ... read more

High Use of Alternative Medicine in Senior Oncology Patients

Aug. 26, 2015 — Many seniors with cancer are also using complementary or alternative medicines that could interfere with their cancer ... read more

Depression: Evidence of Serotonin Signal Transduction Disturbances

Aug. 26, 2015 — Depression and anxiety disorders are the most common psychiatric disorders. Over the last few years, molecular brain imaging using Positron Emission Tomography (PET) has helped us to identify ... read more

Experimental Post-Exposure Antiviral Treatment May Protect Humans from Ebola Virus

Aug. 25, 2015 — For the first time, physicians have demonstrated that antiviral-based therapies have the potential to protect humans from the deadly Ebola virus. The report describes a case-series of eight British ... read more

Opioid Receptor Gene Variations Associated With Neonatal Abstinence Syndrome Severity

Aug. 25, 2015 — A new study indicates that variations in opioid receptor genes are associated with more severe neonatal abstinence syndrome (NAS) in newborn babies. The findings could help lead to the development of ... read more

Aug. 25, 2015 — Scientists have caught a glimpse of the elusive toxic form of the Alzheimer's molecule, during its attempt to bore into the outer covering of a cell decoy, using a new method involving laser ... read more

Aug. 25, 2015 — Pancreatic cancer is extremely deadly and often has a poor prognosis. Researchers are on a mission to develop drugs that will allow physicians to prolong patient survival and, possibly, even ... read more

Mental Visual Imaging Training Improves Multiple Sclerosis Patients' Well-Being

Aug. 25, 2015 — Patients with relapsing-remitting multiple sclerosis (RR-MS), the most common form of the disease, often have deficits in two neuropsychological functions, autobiographical memory (AM) and episodic ... read more

Delay in Administration of Adrenaline and Survival for Children With Cardiac Arrest

Aug. 25, 2015 — Among children with in-hospital cardiac arrest with an initial nonshockable heart rhythm who received epinephrine (adrenaline), delay in administration of epinephrine was associated with a decreased ... read more

Aug. 25, 2015 — New research shows that a modification to the Valsalva maneuver, used to treat people with an abnormally high heart rate, can increase its effectiveness by more than a ... read more

Structural Discoveries Could Aid in Better Drug Design

Aug. 25, 2015 — Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output. These new findings could aid future drug design by giving ... read more

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