Pharmacology News
February 5, 2016

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updated 10:30pm EST

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February 5, 2016

C. Diff Study Provides Insight Into Antibiotic Resistance and Risks for Infection

Feb. 4, 2016 — Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new ... read more

Improvised Naloxone Nasal Sprays Lack Evidence of Absorption and Effect

Feb. 4, 2016 — Naloxone hydrochloride is a medication that can reverse the effects of an opioid overdose. Recently, the US Food and Drug Administration (FDA) approved a nasal naloxone product to replace those ... read more

Feb. 4, 2016 — Scientists have captured atomic images of the virus that causes cold sores in action. Structural details reveal that the virus inserts itself into another protein, jamming an important immune system ... read more

New Insights Into the Function of the Main Class of Drug Targets

Feb. 3, 2016 — About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors. Researchers has now ... read more

What's the Impact of New Marijuana Laws? The Data So Far

Feb. 3, 2016 — How has new legislation affected marijuana use in the United States? The best available data suggest that marijuana use is increasing in adults but not teens, with a decrease in marijuana-related ... read more

Feb. 3, 2016 — For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds ... read more

Use of and Barriers to Access to Opioid Analgesics Worldwide

Feb. 3, 2016 — Use of common opioid painkillers such as codeine, morphine and oxycodone has more than quadrupled in Australia over the past decade and doubled worldwide over the same period. Yet at the same time ... read more

Feb. 3, 2016 — A materials scientist has discovered a way to grow a crystal ball in a lab. Not the kind that soothsayers use to predict the future, but a microscopic version that could be used to encapsulate ... read more

Drug Prevents Key Age-Related Brain Change in Rats

Feb. 2, 2016 — New findings shed light on the mechanisms of cognitive decline and identify potential strategies to stem ... read more

Feb. 2, 2016 — A faulty signaling pathway has been identified that, when corrected, in mice ameliorates the symptoms of Rett syndrome, a devastating neurological condition. The findings could lead to the discovery ... read more

Sstudy Identifies Mechanism for Drug Target to Help Block HIV's Ability to Spread

Feb. 2, 2016 — A new study identifies how RNA-based drug 5-aza-C blocks HIV's ability to spread by converting to DNA before infiltrating the virus. Because RNA drugs are more cost-effective, the findings could ... read more

Adenosine Deaminase May Help the Immune System Fight HIV on Its Own

Feb. 2, 2016 — A new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug, new research shows. The drug, an enzyme called adenosine deaminase, or ADA, ultimately may be ... read more

Antiseptic Baths to Prevent Infections Deemed Effective for Long-Term Use

Feb. 2, 2016 — Long-term use antiseptic soap in bathing critically ill patients to prevent healthcare-associated infections (HAIs) did not cause high levels of resistance in bacteria on the patients' skin, ... read more

Effects on HIV and Ebola

Feb. 2, 2016 — Extracts of the medicinal plant Cistus incanus (Ci) prevent human immunodeficiency viruses from infecting cells, new research shows. Active antiviral ingredients in the extracts inhibit docking of ... read more

Feb. 2, 2016 — Stopping the growth of blood vessels in tumors is a key target for glioblastoma therapies, and imaging methods are essential for initial diagnosis and monitoring the effects of treatments. A team of ... read more

Turning Down the Volume on Cancer

Feb. 2, 2016 — When the audio on your television set is too loud, you simply turn down the volume. What if we could do the same for signaling in our bodies that essentially causes normal cells to turn cancerous? ... read more

Study May Offer Answers for Treating Depression in Alcoholics

Feb. 2, 2016 — A new study is offering a glimmer of hope to alcoholics who find it hard to remain sober because their abstinence is hounded by stubborn, difficult-to-treat ... read more

Experts Cite Multiple Contacts for Hepatitis C Virus Exposure in Ghana

Feb. 1, 2016 — West African residents have frequent opportunities for exposure to the hepatitis C virus, according to a new comprehensive ... read more

Feb. 1, 2016 — A new drug with the potential to aid in vaccine development has been identified by researchers. The drug appears safe, and boosts immunity in mice, say the ... read more

Potential Targeted Therapy for Lung Cancer Identified Using Fly Model

Feb. 1, 2016 — A drug approved by the Food and Drug Administration (FDA) for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small ... read more

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