Pharmacology News
May 27, 2015

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updated 3:57am EDT

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May 27, 2015

New Findings About Mechanisms Underlying Chronic Pain Reveal Novel Therapeutic Strategies

May 26, 2015 — A critical role for a class of cells present in the brain and spinal cord, called microglia, has been discovered for those in pain. Researchers have found microglia to neuron signaling to be crucial ... read more

New UK Research 'Challenges the Assumption That Arthritis Patients Take Their Medication Regularly'

May 26, 2015 — 40% of UK arthritis patients scored low on an adherence questionnaire at least once during their time in a recent study, indicating that they might not be taking their expensive biological therapies ... read more

New Research Leads to FDA Approval of First Drug to Treat Radiation Sickness

May 22, 2015 — New research has led to FDA approval of the use of a drug to treat the effects of radiation exposure following a nuclear incident. The drug, Neupogen, is the first ever approved for the treatment of ... read more

Low Stent Thrombosis Rates With Primary PCI, Regardless of Antithrombotic Choice

May 21, 2015 — Stent thrombosis following urgent angioplasty for acute heart attack occurred in less than 1 percent of patients in a large, 'real-world' registry, regardless of whether the antithrombotic ... read more

Anti-Stroke Drug Effective Treatment for Middle-Ear Infections, Researchers Say

May 21, 2015 — An existing anti-stroke drug is an effective treatment for middle-ear infections, showing the ability to suppress mucus overproduction, improve bacterial clearance and reduce hearing loss, according ... read more

Best and Safest Blood Pressure Treatments in Kidney, Diabetes Patients Compiled

May 22, 2015 — The first definitive summary of the best and safest blood pressure lowering treatments for kidney disease and diabetes patients has been compiled by clinicians. Diabetes and high blood pressure are ... read more

Ledipasvir Plus Sofosbuvir: Hint of Added Benefit in Further Patient Group

May 22, 2015 — Documents subsequently submitted by the manufacturer show an advantage in sustained virologic response also for hepatitis C infection of genotype 1 with HIV coinfection without cirrhosis of the ... read more

How a Schizophrenia Risk Gene Affects the Brain

May 22, 2015 — Brain imaging studies have already revealed that mental illnesses involve alterations in both the structure and connectivity of the brain. Scientists have now, for the first time, shown how the ... read more

May 21, 2015 — A new chemical technology uses cancer cells' own protein-degrading machinery to destroy, rather than merely inhibit, cancer proteins. Researchers developed the strategy as a way to develop ... read more

Novel Drug Combo Improves Function of Cystic Fibrosis Protein

May 20, 2015 — A novel two-drug combination has the potential to target and restore a defective protein underlying cystic fibrosis (CF), according to two phase III clinical trials conducted at 187 medical centers ... read more

Cholesterol Drugs Associated With 30 Percent Lower Stroke Risk in Healthy Older Adults

May 19, 2015 — Use of cholesterol lowering drugs is associated with a one third lower risk of stroke in older adults without previous disease, finds a study. If replicated, the study results suggest that lipid ... read more

Researchers Discover Molecular Approach to Promote Cancer Cell Death

May 21, 2015 — Lung cancer researchers have discovered a novel strategy to exploit apoptosis, a form of programmed cell death, for the treatment of lung cancer. The protein Bcl-2 is a known target for cancer ... read more

May 21, 2015 — An extract from the thunder god vine, which has a long history of use in traditional Chinese medicine, reduces food intake and causes up to a 45 percent decrease in body weight in obese mice. The ... read more

Scientists Unveil Prostate Cancer's 'Rosetta Stone'

May 21, 2015 — Almost 90 percent of men with advanced prostate cancer carry genetic mutations in their tumors that could be targeted by either existing or new cancer drugs, a landmark new study reveals. Scientists ... read more

Compound Has Potential for Treating Rheumatoid Arthritis

May 21, 2015 — A new study outlines a chemical compound with potential for treating rheumatoid arthritis. Rheumatoid arthritis is a chronic autoimmune disorder that affects an estimated 1.3 million people in the ... read more

'Imperfect Drug Penetration' Speeds Pathogens' Resistance, Study Finds

May 18, 2015 — Prescribing patients two or more drugs that do not reach the same parts of the body could accelerate a pathogen's resistance to all of the drugs being used in treatment, according to new ... read more

Adolescents, Drugs and Dancing

May 18, 2015 — A new study is the first to examine the sociodemographic correlates of rave attendance and relationships between rave attendance and recent (12-month) use of various drugs in a representative US ... read more

Novel Insights in MET-Proto-Oncogene Might Lead to Optimizing Cancer Treatment

May 18, 2015 — The MET-proto-oncogene is involved in the pathogenesis of several tumors and therefore represents an interesting target for future therapies currently tested in dozens of clinical trials. Researchers ... read more

Major Breakthrough Against Rare Kidney Disease

May 21, 2015 — A significant breakthrough has been made in the fight against Membranous Nephropathy (MN) -- a rare kidney disease which can lead to kidney failure -- scientists report in a new ... read more

May 21, 2015 — Antimicrobial resistance in bacteria poses a global threat to public health. Common antibiotics are often ineffective in treating infectious diseases because pathogens acquire resistance genes. These ... read more

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