Pharmacology News
September 4, 2015

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September 4, 2015

Surgery Achieves Better Long-Term Control of Type 2 Diabetes Than Standard Therapy

Sep. 3, 2015 — Metabolic or bariatric surgery may be more effective than standard medical treatments for the long-term control of type 2 diabetes in obese patients, according to a new study. The study is the first ... read more

Genetic Factors Drive Roles of Gut Bacteria in Diabetes, Obesity

Sep. 3, 2015 — One strain of mice that were genetically prone to become obese became resistant to excess weight gain after their populations of gut microbiota were transformed simply by an sharing an environment ... read more

One Step Closer to Cheaper Antivenom

Sep. 3, 2015 — Researchers involved in an international collaboration across six institutions have successfully identified the exact composition of sea snake venom, which makes the future development of synthetic ... read more

Acupuncture Reduces Hot Flashes in Breast Cancer Survivors

Sep. 3, 2015 — Acupuncture may be a viable treatment for women experiencing hot flashes as a result of estrogen-targeting therapies to treat breast cancer, according to a new study. Hot flashes are particularly ... read more

Targeting Newly Discovered Pathway Sensitizes Tumors to Radiation and Chemotherapy

Sep. 3, 2015 — In some patients, aggressive cancers can become resistant to chemotherapy and radiation treatments. In a new paper, researchers identified a pathway that causes the resistance and a new therapeutic ... read more

Sep. 3, 2015 — The multifunctional ubiquitin tweaks the activity of newly made proteins, which can influence DNA damage repair via BRCA1 and anti-inflammatory responses, scientists report. One enzyme in particular, ... read more

Health Risks of Saturated Fats Aggravated by Immune Response

Sep. 3, 2015 — High levels of saturated fat in the blood could make an individual more prone to inflammation and tissue damage, a new study suggests. The new research shows that the presence of saturated fats ... read more

Drug for Fungal Infections in Lung Transplant Recipients Increases Risk for Cancer, Death

Sep. 3, 2015 — Voriconazole, a prescription drug commonly used to treat fungal infections in lung transplant recipients, significantly increases the risk for skin cancer and even death, according to a new ... read more

Needle Exchange Program Prevented 120 New Cases of HIV in Two Years, Study Suggests

Sep. 3, 2015 — The District of Columbia's needle exchange program prevented 120 new cases of HIV infection and saved an estimated $44 million over just a two-year period, according to a first-of-a-kind ... read more

Long-Term Study Links Common Psychiatric Disorders With Increased Risk of Violent Reoffending in Ex-Prisoners

Sep. 2, 2015 — Ex-prisoners with common psychiatric disorders such as bipolar disorder (manic-depressive disorder) and alcohol and drug abuse are substantially more likely to commit a violent crime after release ... read more

Sep. 2, 2015 — New research may help explain why drug treatments for addiction and depression don't work for some patients. The conditions are linked to reward and aversion responses in the brain. And the ... read more

Telomerase Targeting Drug Demonstrates Benefit in Myelofibrosis Treatment

Sep. 2, 2015 — Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a new ... read more

Researchers Identify a New Approach for Lowering Harmful Lipids

Sep. 2, 2015 — A new approach for lowering 'bad' lipids in blood circulation has been identified by researchers, a critical means to combat devastating cardiovascular diseases such as ... read more

Researchers Report Long-Term Remissions in First Personalized Cell Therapy Trial

Sep. 2, 2015 — Eight of 14 patients in the first trial of a personalized cellular therapy for chronic lymphocytic leukemia (CLL) responded to the therapy, with some complete remissions continuing past four and a ... read more

Cellular Recycling Complexes May Hold Key to Chemotherapy Resistance

Sep. 2, 2015 — Upsetting the balance between protein synthesis, misfolding, and degradation drives cancer and neurodegeneration. Recent cancer treatments take advantage of this knowledge with a class of drugs that ... read more

Sep. 2, 2015 — Bacteria's ability to become resistant to antibiotics is a growing issue in health care: Resistant strains result in prolonged illnesses and higher mortality rates. One way to combat this is to ... read more

Antipsychotics Inappropriately Prescribed to People With Intellectual Disabilities

Sep. 1, 2015 — Large numbers of people with intellectual disabilities in the UK are being inappropriately prescribed antipsychotic drugs, finds a new study. Intellectual disability is a lifelong condition that ... read more

Sep. 1, 2015 — New technology that transforms a cell phone into a powerful, mobile microscope could significantly improve malaria diagnoses and treatment in developing countries that often lack the resources to ... read more

Researchers Develop a Likely New Combo Treatment for the Deadliest Form of Brain Cancer

Sep. 1, 2015 — Scientists have developed a potentially promising new combination therapy for glioblastoma, the deadliest form of brain cancer. Glioblastoma, also known as grade IV glioma, is the most aggressive ... read more

Another Way Urate May Protect Against Parkinson's Disease

Sep. 1, 2015 — A study from members of the research team investigating whether increasing blood levels of the antioxidant urate can slow the progression of Parkinson's disease has found that the ... read more

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