Pharmacology News
October 4, 2015

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updated 3:59pm EDT

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October 4, 2015

High Opioid Use in Older People With COPD Raises Safety Concerns

Oct. 2, 2015 — Researchers are raising safety concerns about high rates of new opioid use among older adults with COPD, according to a study. Opioids, such as codeine, oxycodone and morphine might be prescribed ... read more

New Study Removes Cancer Doubt for Multiple Sclerosis Drug

Oct. 1, 2015 — Researchers are calling on the medical community to reconsider developing a known drug to treat people with relapsing multiple sclerosis (MS) after new evidence shows it does not increase the risk of ... read more

Preclinical Drug Developed to Prevent Gastrointestinal Side Effects of Type 1 Diabetes

Oct. 1, 2015 — Up to 80 percent of individuals living with long-term type 1 diabetes experience gastrointestinal symptoms such as abdominal distension, irritable bowel syndrome, and fecal incontinence. A study ... read more

Search Engine for More Accurate, Fast Recognition of Metabolites

Oct. 1, 2015 — Metabolites are small molecules, such as sugars, fatty acids and amino acids that, among other things, serve as sources of energy in the cells and as building materials for cell walls. For ... read more

What Is the Cost of Lung Cancer in Germany?

Oct. 1, 2015 — With more than 50,000 newly diagnosed cases each year, lung cancer is one of the most common types of cancer in Germany. As yet, however, very few statistics are available on the care situation of ... read more

Screening for Mental Health Issues in a Pediatric Emergency Department

Oct. 1, 2015 — Investigators piloted a brief mental health screening tool to be used with patients accessing the emergency department for medical complaints who might be at risk for mental health problems. Of the ... read more

Divorcing Drugs and Violence Is Key to Saving U.S. Drug Policy, Research Shows

Oct. 1, 2015 — New research is being used in public policy discussions surrounding changes to mandatory minimum sentences involving nonviolent drug offenders through the Smarter Sentencing ... read more

Doctors Trained to Be Confidantes for Risk-Taking Teenagers

Oct. 1, 2015 — Doctors have successfully reduced risk-taking behavior in teenagers and young people, in a world-first trial, say authors of a new report. The researchers recommend trainee doctors should be taught ... read more

Aspects of Patient/physician Interaction May Help Alleviate Heartburn Symptoms

Oct. 1, 2015 — The results of a small study of patients being treated for chronic heartburn suggest that the longer, more comprehensive interaction that is typical of visits with complementary and integrative ... read more

Scientific Literature Overstates Psychotherapy's Effectiveness in Treating Depression

Oct. 1, 2015 — The scientific literature paints an overly rosy picture of the efficacy of psychotherapy for depression comparable to the bias previously found in reports of treatments with antidepressant ... read more

Scientists Identify Key Receptor as Potential Target for Treatment of Autism

Oct. 1, 2015 — Scientists have uncovered a significant -- and potentially treatable -- relationship between a chemical that helps transmit signals in the brain and genetic mutations present in a subset of ... read more

Proof-of-Concept for Low-Cost Drug Made in Lettuce

Oct. 1, 2015 — Scientists have used a plant-based system to make shelf-stable drugs. The researchers confirmed the viability of their method for FDA approval and human use, producing an effective drug that promotes ... read more

Scientists Discover How to Trap Cancer Cells Before They Spread

Oct. 1, 2015 — A new way has been found to potentially 'fence in' a tumor and help stop cancer cells spreading, according to a study. The research team behind the results showed that adding experimental ... read more

Human Tumor 'Avatars' Reveal New Genetic Sources of Drug Response in Late-Stage Colorectal Cancer Therapy

Sep. 30, 2015 — Using pieces of human tumors grafted into mice, a team of researchers has identified new mutations in six genes related to drug resistance and sensitivity in late-stage colorectal ... read more

Experimental Cancer Drug Shows Therapeutic Promise in Mouse Models of Multiple Sclerosis

Sep. 30, 2015 — An experimental drug originally identified in a National Cancer Institute library of chemical compounds as a potential therapy for brain and basal cell cancers improves the symptoms of mice with a ... read more

DNA-Based Vaccine Clears Nearly Half of Precancerous Cervical Lesions in Clinical Trial

Sep. 30, 2015 — Using a novel synthetic platform for creating vaccines a team of researchers has successfully eradicated precancerous cervical lesions in nearly half of the women who received an investigational ... read more

Insight on How a New Class of Antidepressants Works

Sep. 30, 2015 — The experimental drugs target brain cells’ ability to respond to the chemical messenger glutamate, however, it has been unclear how they work. The recent discovery of a molecular amplification ... read more

Study's Message to Recovering Alcoholics: Quit Smoking to Stay Sober

Sep. 30, 2015 — Adult smokers with a history of problem drinking who continue smoking are at a greater risk of relapsing three years later compared with adults who do not smoke. While treatments for alcohol abuse ... read more

Sep. 30, 2015 — When it comes to treating depression, how well a person responds to a fake medicine may determine how well they'll respond to a real one, new research finds. Those who can muster their ... read more

Scientists Pioneer 3-D-Printed Drug Delivering Micro-Needles

Sep. 29, 2015 — Researchers have developed a new technique to produce a 3-D 'micro-printed' array of needles capable of drug delivery. The technique would offer a pain-free drug delivery device that would ... read more

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