Pharmacology News
July 31, 2015

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July 31, 2015

New Cancer Marker Identified; Possible Therapeutic Target for Breast Cancer

July 31, 2015 — Basal-like breast cancer (BLBC) is an aggressive form of breast cancer and is often referred to as "triple negative," which means it is not responsive to the common medical therapeutics. ... read more

July 31, 2015 — A synthetic membrane that self assembles and is easily produced may lead to better gas separation, water purification, drug delivery and DNA recognition, according to an international team of ... read more

Hospital Penalties Based on Total Number of Blood Clots May Be Unfairly Imposed, Study Shows

July 29, 2015 — Researchers say their review of 128 medical case histories suggests that financial penalties imposed on Maryland hospitals based solely on the total number of patients who suffer blood clots in the ... read more

July 29, 2015 — The formation of G protein-coupled receptors (GPCRs), which allows understanding the unexpected behavior of some antagonists that block physiological responses, has been the focus of recent ... read more

Overcoming Why a New Treatment Is Resisted by Lung Cancer

July 29, 2015 — A promising agent for the treatment of cancer has so far had little effect on the most common lung tumours, but new research has suggested how this resistance might be ... read more

Naturally Occurring Protein Fragment Found in the Brain Inhibits Key Enzyme Implicated in Alzheimer's Disease

July 29, 2015 — A natural protein fragment produced in the brain can act as an inhibitor of a key enzyme implicated in the onset of Alzheimer's disease, researchers have discovered for the first time. This is a ... read more

Scientists Discover Link Between Common Medications and Serious Falls in Older Men

July 28, 2015 — A significant link between serious falls causing injury in older men and a particular group of commonly used medicines has been identified by a group of researchers. Many medicines which are commonly ... read more

New Tool Uses 'Drug Spillover' to Match Cancer Patients With Treatments

July 28, 2015 — A new article describes a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker predicts what genetics are truly driving the cancer in any population of cells and ... read more

Big Data Gives New Insight Into Blood Pressure Reduction Role of Commonly Prescribed Drug

July 28, 2015 — A drug commonly prescribed to conserve potassium in the blood also significantly lowers blood pressure when taken in conjunction with a diuretic frequently prescribed to patients with hypertension, a ... read more

Sleepy Fruitflies Get Mellow

July 28, 2015 — Whether you're a human, a mouse, or even a fruitfly, losing sleep is a bad thing, leading to physiological effects and behavioral changes. Researchers used fruitflies to probe deeper into the ... read more

Anti-Inflammatory Drug Acts Against Ovarian Cancer, Scientists Find

July 28, 2015 — A non-steroidal anti-inflammatory drug (NSAID) called ketorolac helped women with ovarian cancer to survive longer, researchers report. Ketorolac, marketed as Toradol®, is approved for clinical use ... read more

July 28, 2015 — Pharmaceutical firms 'underinvest' in long-term research to develop new cancer-fighting drugs due to the greater time and cost required to conduct such research, according to a newly ... read more

National Study of Deep Brain Stimulation for Depression Fails to Demonstrate Efficacy

July 28, 2015 — Depression is a leading cause of disability worldwide, and treatment-resistant symptoms of depression have a terrible personal and societal cost. They can devastate lives, careers, and families. Some ... read more

Pharmacy Expenditures for Children With Serious Chronic Illness

July 28, 2015 — In an analysis of expenditures for outpatient pharmacy products used by publicly insured children with serious chronic illness in California, treating hemophilia accounted for about 40 percent of ... read more

Race, Institutional Factors Play an Important Role in Pharmacogenomic Trial Participation

July 28, 2015 — The participation rate of patients in pharmacogenomic trials has been the focus of recent study. The research has concluded that there are a number of factors at the patient, physician, institution ... read more

Stress Hormone Reduces Heroin Cravings

July 28, 2015 — Every addiction is characterized by a strong desire for a certain addictive substance, be it nicotine, alcohol or other drug. Researchers recently conducted a study on heroin addiction and ... read more

July 28, 2015 — Hepatitis B infections are among the most common infectious diseases worldwide. In the scope of an international study, scientists have determined how often the chronic infection occurs in different ... read more

Metagenome-Wide Association Study on Oral Microbiome Uncovered Markers for Rheumatoid Arthritis

July 28, 2015 — Researchers have reported their study on the oral and gut microbiome in rheumatoid arthritis (RA). The results show that the gut and oral microbiome are involved in the pathophysiology and management ... read more

Researchers Create Promising New Mouse Model for Lung Injury Repair

July 28, 2015 — Researchers have created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the origins of lung disease and provide a system by which new therapies can ... read more

New Drug for Blood Cancers Now in Five Phase II Clinical Trials

July 28, 2015 — The safety and dosing of a new drug for treating blood cancers has now been established by a group of scientists. The drug is a small molecule inhibitor that suppresses the activity of a signaling ... read more

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