Pharmacology News
September 3, 2015

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updated 4:58am EDT

More Pharmacology News
September 3, 2015

Sep. 2, 2015 — New research may help explain why drug treatments for addiction and depression don't work for some patients. The conditions are linked to reward and aversion responses in the brain. And the ... read more

Telomerase Targeting Drug Demonstrates Benefit in Myelofibrosis Treatment

Sep. 2, 2015 — Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a new ... read more

Sep. 2, 2015 — Scientists have pinpointed a population of neurons in the brain that influences whether one drink leads to two, which could ultimately lead to a cure for alcoholism and other addictions. Their study ... read more

Another Way Urate May Protect Against Parkinson's Disease

Sep. 1, 2015 — A study from members of the research team investigating whether increasing blood levels of the antioxidant urate can slow the progression of Parkinson's disease has found that the ... read more

Injection Drug Use Limits Benefits of Surgery for Treatment of Heart Lining Infection

Sep. 1, 2015 — Injection drug users who undergo surgery for infective endocarditis (IE) have a significantly higher risk of reoperation or death between 3 and 6 months after surgery compared to patients who develop ... read more

With Tobacco, What You Don't Know Can Kill You Sooner

Aug. 31, 2015 — The public shows “considerable lack of knowledge” about the risk associated with different types of tobacco products, researchers say. What people can benefit from is knowing the varying levels ... read more

Aug. 31, 2015 — Working with mice, researchers have added to evidence that a commonly prescribed antidepressant called fluoxetine helps stroke victims improve movement and coordination, and possibly ... read more

Medication Treatment for Opioid Use Disorders in Primary Care Increases Patient Access

Aug. 31, 2015 — Expanding the number of sites offering office-based opioid treatment with buprenorphine utilizing addiction nurse care managers, trainings and technical support resulted in more physicians becoming ... read more

Closer to a Treatment for 'Asthma of the Esophagus'

Aug. 31, 2015 — Scientists have elucidated the chemical process behind a mysterious gastrointestinal disease that is becoming more frequent every day: the eosinophilic esophagitis (EoE), also known as the ... read more

Fatal Bleeding Rare With Extended Dual Antiplatelet Therapy

Aug. 31, 2015 — Fatal bleeding is rare with extended dual antiplatelet therapy, according to a secondary analysis of the DAPT Study. Bleeding-related mortality accounted for a minority of deaths in patients treated ... read more

Prasugrel Associated With Increased Major Bleeding in High-Risk Patients With Stable Coronary Artery Disease

Aug. 31, 2015 — Prasugrel-based dual antiplatelet therapy is associated with increased major bleeding after stent implantation for high-risk patients with stable coronary artery disease, according to a secondary ... read more

Ticagrelor Administered in the Ambulance Reduces Ischaemic Events 24 Hours After PCI

Aug. 31, 2015 — Ticagrelor administered in the ambulance reduces ischaemic events 24 hours after primary percutaneous coronary intervention (PCI), according to new ... read more

Aug. 31, 2015 — Cancer cells survive the stressful environment inside a tumor in part through autophagy, the controlled digestion and recycling of damaged components. However, blocking the process doesn't kill ... read more

Research Team Creates Model to Predict Cellular Evolution

Aug. 31, 2015 — Scientists have not been able to understand and predict how cells evolve in our bodies, and this process is important because evolving cell populations are at the core of drug-resistant infections ... read more

Half-Dose Combo of Common Diuretics a 'Win-Win' for Hypertension

Aug. 31, 2015 — The combination of two commonly used diuretics, each at half dose, can significantly reduce blood pressure without the side-effects caused by full doses of either alone, researchers have ... read more

Spironolactone 'a Clear Winner' for Resistant Hypertension

Aug. 31, 2015 — In patients with poor blood pressure control despite treatment with a combination of three drugs (‘resistant hypertension’), addition of the diuretic spironolactone was significantly more ... read more

Lcz696 Targets Blood Pressure and Arterial Stiffness

Aug. 31, 2015 — The combination drug valsartan/sacubitril known as LCZ696 significantly reduced aortic systolic blood pressure and pulse pressure compared to the standard angiotensin receptor blocker (ARB) ... read more

New Analysis Adds Heart Failure Data for Sitagliptin

Aug. 31, 2015 — Patients with type-2 diabetes and cardiovascular disease can safely take the antihyperglycemic drug sitagliptin without an increased risk of cardiovascular complications - even if they have a history ... read more

Study Quells Concerns About NAID Safety

Aug. 31, 2015 — In older patients with arthritis and no history of cardiovascular disease, chronic use of any non-steroidal anti-inflammatory drug appears safe from a cardiovascular and gastrointestinal stand-point, ... read more

Close Friendships in Adolescence Predict Health in Adulthood

Aug. 31, 2015 — Teens are often warned to beware the undue influence of peer pressure, but new research suggests that following the pack in adolescence may have some unexpected benefits for physical health in early ... read more

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