Pharmacology News
September 2, 2015

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updated 2:28am EDT

More Pharmacology News
September 2, 2015

Another Way Urate May Protect Against Parkinson's Disease

Sep. 1, 2015 — A study from members of the research team investigating whether increasing blood levels of the antioxidant urate can slow the progression of Parkinson's disease has found that the ... read more

Injection Drug Use Limits Benefits of Surgery for Treatment of Heart Lining Infection

Sep. 1, 2015 — Injection drug users who undergo surgery for infective endocarditis (IE) have a significantly higher risk of reoperation or death between 3 and 6 months after surgery compared to patients who develop ... read more

Medication Treatment for Opioid Use Disorders in Primary Care Increases Patient Access

Aug. 31, 2015 — Expanding the number of sites offering office-based opioid treatment with buprenorphine utilizing addiction nurse care managers, trainings and technical support resulted in more physicians becoming ... read more

Fatal Bleeding Rare With Extended Dual Antiplatelet Therapy

Aug. 31, 2015 — Fatal bleeding is rare with extended dual antiplatelet therapy, according to a secondary analysis of the DAPT Study. Bleeding-related mortality accounted for a minority of deaths in patients treated ... read more

Prasugrel Associated With Increased Major Bleeding in High-Risk Patients With Stable Coronary Artery Disease

Aug. 31, 2015 — Prasugrel-based dual antiplatelet therapy is associated with increased major bleeding after stent implantation for high-risk patients with stable coronary artery disease, according to a secondary ... read more

Ticagrelor Administered in the Ambulance Reduces Ischaemic Events 24 Hours After PCI

Aug. 31, 2015 — Ticagrelor administered in the ambulance reduces ischaemic events 24 hours after primary percutaneous coronary intervention (PCI), according to new ... read more

Research Team Creates Model to Predict Cellular Evolution

Aug. 31, 2015 — Scientists have not been able to understand and predict how cells evolve in our bodies, and this process is important because evolving cell populations are at the core of drug-resistant infections ... read more

Half-Dose Combo of Common Diuretics a 'Win-Win' for Hypertension

Aug. 31, 2015 — The combination of two commonly used diuretics, each at half dose, can significantly reduce blood pressure without the side-effects caused by full doses of either alone, researchers have ... read more

Spironolactone 'a Clear Winner' for Resistant Hypertension

Aug. 31, 2015 — In patients with poor blood pressure control despite treatment with a combination of three drugs (‘resistant hypertension’), addition of the diuretic spironolactone was significantly more ... read more

Lcz696 Targets Blood Pressure and Arterial Stiffness

Aug. 31, 2015 — The combination drug valsartan/sacubitril known as LCZ696 significantly reduced aortic systolic blood pressure and pulse pressure compared to the standard angiotensin receptor blocker (ARB) ... read more

New Analysis Adds Heart Failure Data for Sitagliptin

Aug. 31, 2015 — Patients with type-2 diabetes and cardiovascular disease can safely take the antihyperglycemic drug sitagliptin without an increased risk of cardiovascular complications - even if they have a history ... read more

Study Quells Concerns About NAID Safety

Aug. 31, 2015 — In older patients with arthritis and no history of cardiovascular disease, chronic use of any non-steroidal anti-inflammatory drug appears safe from a cardiovascular and gastrointestinal stand-point, ... read more

Close Friendships in Adolescence Predict Health in Adulthood

Aug. 31, 2015 — Teens are often warned to beware the undue influence of peer pressure, but new research suggests that following the pack in adolescence may have some unexpected benefits for physical health in early ... read more

Food May Be Addictive: Food Craving May Be 'Hard-Wired' in the Brain

Aug. 31, 2015 — An international group of researchers have found that food craving activates different brain networks between obese and normal weight patients. This indicates that the tendency to want food may be ... read more

A Single Cocaine Dose Lowers Perceptions of Sadness and Anger

Aug. 30, 2015 — A single dose of cocaine can interfere with the ability to recognize negative emotions such as anger and sadness, according to new ... read more

New Synthetic Tumor Environments Make Cancer Research More Realistic

Aug. 28, 2015 — Tumors are notoriously difficult to study in their natural habitat -- body tissues -- but a new synthetic tissue environment may give cancer researchers the next-best look at tumor growth and ... read more

Medicinal Marijuana: Patients Battle Stigma and Misunderstanding

Aug. 28, 2015 — New research examines the experiences of California residents who have been prescribed medical marijuana and the stigma they experience from public opinion.  The findings indicate that the stigma of ... read more

Brain Scans Predict Response to Antipsychotic Medications

Aug. 28, 2015 — Investigators have discovered that brain scans can be used to predict patients' response to antipsychotic drug ... read more

Aug. 27, 2015 — Scientists have identified how mutations in the IKZF1 gene contribute to a high-risk leukemia subtype and drugs that may enhance the effectiveness of targeted ... read more

Interrupting Sitting With Walking Breaks Improves Children's Blood Sugar

Aug. 27, 2015 — Taking 3-minute breaks to walk in the middle of a TV marathon or other sedentary activity can improve children's blood sugar compared to continuously sitting, according to a new ... read more

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