Pharmacology News
December 1, 2015

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updated 8:00am EST

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December 1, 2015

New Gene Map Reveals Cancer's Achilles Heel

Nov. 25, 2015 — Scientists have mapped out the genes that keep our cells alive, creating a long-awaited foothold for understanding how our genome works and which genes are crucial in disease like ... read more

Researchers Assess Use of Drug-Susceptible Parasites to Fight Drug Resistance

Nov. 25, 2015 — A new model for evaluating a potential new strategy in the fight against drug-resistant diseases has been developed by experts. The strategy would take advantage of parasite refugia--host populations ... read more

Antibody-Drug Compounds and Immunotherapy to Treat Breast Cancer

Nov. 25, 2015 — To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years. ... read more

Immunotherapy for Type 1 Diabetes Deemed Safe in First US Trial

Nov. 25, 2015 — Patients experienced no serious adverse reactions after receiving infusions of as many as 2.6 billion cells that had been specially selected to protect the body's ability to produce insulin, ... read more

New Technology Promises Fast, Accurate Stroke Diagnosis

Nov. 25, 2015 — A new approach to identifying biomarkers in blood has proven successful in helping diagnose stroke, and the technology could be expanded to diagnose such conditions as concussion, some forms of ... read more

Discovery Could Open Door to Frozen Preservation of Tissues, Whole Organs

Nov. 25, 2015 — A new approach to 'vitrification,' or ice-free cryopreservation, has been discovered, which could ultimately allow a much wider use of extreme cold to preserve tissues and even organs for ... read more

Anticancer Agent FL118 More Potent Than Its Analogs, Not Prone to Typical Channels of Resistance

Nov. 25, 2015 — A new synthetic form of camptothecin appears to have greater potency, longer efficacy and fewer adverse side effects than irinotecan and topotecan, report ... read more

Nov. 25, 2015 — What doesn't kill you could cure you. A growing interest in the therapeutic value of animal venom has led data scientists to create the first catalog of known animal toxins and their ... read more

Nov. 25, 2015 — The burst of energy and hyperactivity that comes with a cocaine high is a rather accurate reflection of what's going on in the brain of its users, finds a study. Through experiments conducted in ... read more

Nov. 25, 2015 — Researchers are studying whether plant sterols can be used as a natural alternative to drug therapy for pregnant women who have high cholesterol. While it’s normal for a woman’s cholesterol to ... read more

Promising Drug Combination for Advanced Prostate Cancer

Nov. 25, 2015 — A new drug combination may be effective in treating men with metastatic prostate cancer. Preliminary results of this new approach are encouraging and have led to an ongoing international study being ... read more

Combination Therapy Can Prevent Cytostatic Resistance

Nov. 25, 2015 — Researchers have found a new way of preventing resistance to cytostatics used in the treatment of cancers such as medulloblastoma, the most common form of malignant brain tumor in children. The ... read more

New Diet Provides Hope for Treating Patients With Drug Resistant Epilepsy

Nov. 25, 2015 — A specific diet can be used to help treat patients with uncontrolled epilepsy, a new study indicates. The findings reveal how the ketogenic diet acts to block seizures in patients with drug-resistant ... read more

Nov. 24, 2015 — A metal-free process has been developed for the rapid synthesis of elusive small-molecule catalysts that promise to speed the making of novel chemicals, including ... read more

Investigational Drug May Prevent Life-Threatening Muscle Loss in Advanced Cancers

Nov. 24, 2015 — New data describes how an experimental drug can stop life-threatening muscle wasting (cachexia) associated with advanced cancers and restore muscle health. The experimental agent, known as AR-42 ... read more

Immune-Disorder Treatment in Mice Holds Potential for Multiple Sclerosis Patients

Nov. 24, 2015 — A simple, rapid way to treat an immune-related disorder in mice has been identified by researchers, an approach that could eventually help multiple sclerosis patients after further ... read more

Pre-Travel Advice Does Not Reduce the Risk of Falling Ill While Traveling

Nov. 24, 2015 — Traveling abroad involves risk of illnesses and carriage of antibiotic resistant bacteria, especially among students. Illnesses such as travelers’ diarrhea and respiratory tract infections are most ... read more

Children Who Take ADHD Medicines Have Trouble Sleeping, New Study Shows

Nov. 23, 2015 — Children given ADHD stimulant medications take significantly longer to fall asleep, have poorer quality sleep and sleep for shorter periods, shows new ... read more

Adults Aged 50-59 Now Largest Age Group in Opioid Treatment Programs

Nov. 23, 2015 — Researchers found a pronounced age trend in those utilizing opioid treatment programs from 1996 to 2012, with adults aged 50 and older becoming the majority treatment population in New York City, ... read more

Expensive Drugs That Cure Hepatitis C Are Worth the Cost, Even at Early Stages of Liver Fibrosis

Nov. 23, 2015 — It is cost effective to give patients expensive new hepatitis C drugs much earlier than some insurers now pay for them. Researchers were surprised by these findings, since the drugs can cost up to ... read more

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