Pharmacology News
August 31, 2015

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updated 11:58pm EDT

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August 31, 2015

Medication Treatment for Opioid Use Disorders in Primary Care Increases Patient Access

Aug. 31, 2015 — Expanding the number of sites offering office-based opioid treatment with buprenorphine utilizing addiction nurse care managers, trainings and technical support resulted in more physicians becoming ... read more

Prasugrel Associated With Increased Major Bleeding in High-Risk Patients With Stable Coronary Artery Disease

Aug. 31, 2015 — Prasugrel-based dual antiplatelet therapy is associated with increased major bleeding after stent implantation for high-risk patients with stable coronary artery disease, according to a secondary ... read more

Ticagrelor Administered in the Ambulance Reduces Ischaemic Events 24 Hours After PCI

Aug. 31, 2015 — Ticagrelor administered in the ambulance reduces ischaemic events 24 hours after primary percutaneous coronary intervention (PCI), according to new ... read more

New Analysis Adds Heart Failure Data for Sitagliptin

Aug. 31, 2015 — Patients with type-2 diabetes and cardiovascular disease can safely take the antihyperglycemic drug sitagliptin without an increased risk of cardiovascular complications - even if they have a history ... read more

Close Friendships in Adolescence Predict Health in Adulthood

Aug. 31, 2015 — Teens are often warned to beware the undue influence of peer pressure, but new research suggests that following the pack in adolescence may have some unexpected benefits for physical health in early ... read more

Food May Be Addictive: Food Craving May Be 'Hard-Wired' in the Brain

Aug. 31, 2015 — An international group of researchers have found that food craving activates different brain networks between obese and normal weight patients. This indicates that the tendency to want food may be ... read more

A Single Cocaine Dose Lowers Perceptions of Sadness and Anger

Aug. 30, 2015 — A single dose of cocaine can interfere with the ability to recognize negative emotions such as anger and sadness, according to new ... read more

New Synthetic Tumor Environments Make Cancer Research More Realistic

Aug. 28, 2015 — Tumors are notoriously difficult to study in their natural habitat -- body tissues -- but a new synthetic tissue environment may give cancer researchers the next-best look at tumor growth and ... read more

Medicinal Marijuana: Patients Battle Stigma and Misunderstanding

Aug. 28, 2015 — New research examines the experiences of California residents who have been prescribed medical marijuana and the stigma they experience from public opinion.  The findings indicate that the stigma of ... read more

Brain Scans Predict Response to Antipsychotic Medications

Aug. 28, 2015 — Investigators have discovered that brain scans can be used to predict patients' response to antipsychotic drug ... read more

Aug. 27, 2015 — Scientists have identified how mutations in the IKZF1 gene contribute to a high-risk leukemia subtype and drugs that may enhance the effectiveness of targeted ... read more

Interrupting Sitting With Walking Breaks Improves Children's Blood Sugar

Aug. 27, 2015 — Taking 3-minute breaks to walk in the middle of a TV marathon or other sedentary activity can improve children's blood sugar compared to continuously sitting, according to a new ... read more

Researchers Thwart Cancer Cells by Triggering 'Virus Alert'

Aug. 27, 2015 — Working with human cancer cell lines and mice, researchers have found a way to trigger a type of immune system 'virus alert' that may one day boost cancer patients' response to ... read more

Viral Infection in Colon Cancer Stem Cells Mimicked; Druggable Target Identified

Aug. 27, 2015 — Researchers targeting colorectal cancer stem cells – the root cause of disease, resistance to treatment and relapse – have discovered a mechanism to mimic a virus and potentially trigger an ... read more

Parkinson’s Disease Brain Cells at Risk of Burnout, Like an Overheating Motor

Aug. 27, 2015 — The death of brain cells in Parkinson’s disease may be caused by a form of cellular energy crisis in neurons that require unusually high quantities of energy to carry out their job of regulating ... read more

Cause of Resilience to Tinnitus and Potential Drug Therapy Identified

Aug. 27, 2015 — Researchers have identified in an animal model the molecular mechanisms behind resilience to noise-induced tinnitus and a possible drug therapy that could reduce susceptibility to this chronic and ... read more

Framework for Value-Based Pricing of Cancer Drugs

Aug. 27, 2015 — At a time when cancer drug prices are rising rapidly, an innovative new study provides the framework for establishing value-based pricing for all new oncology drugs entering the ... read more

Probiotics Show No Impact Preventing Gastrointestinal Colonization With Drug-Resistant Bugs in ICU

Aug. 27, 2015 — Probiotics show no benefit for preventing or eliminating gastrointestinal colonization with drug-resistant organisms in patients in the intensive care unit compared to standard care, according to new ... read more

Health Workers Wasting Expensive Malaria Drugs in Nigeria

Aug. 27, 2015 — Health providers trained to perform malaria rapid diagnostic tests are still prescribing valuable malaria medicines to patients who do not have malaria, according to new ... read more

Exploding the Drug Deadlock: Repurposing Nitroglycerin for Anti-Cancer Treatments

Aug. 27, 2015 — For over a century, nitroglycerin has been used medically – particularly in the treatment of angina, or chest pain. It is a safe, cheap and effective treatment. Now, researchers have found that ... read more

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