Pharmacology News
February 11, 2016

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updated 2:31pm EST

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February 11, 2016

New Treatment Option for the Acute Phase of the Rare Disease TTP

Feb. 11, 2016 — Thrombotic Thrombocytopenic Purpura (TTP) is a rare disorder caused by an enzyme deficiency. This can be heriditary or can be acquired as an autoimmune condition. Due to the associated excessive ... read more

'LIGHTSABR,' a Cheap, Portable Drug-Discovery System Developed

Feb. 10, 2016 — A device that can do the functional equivalent of high-throughput compound screening on an ultra-miniaturized scale has been developed by ... read more

Scientists Write Document Explaining Zika Virus, Urge Vigilance

Feb. 10, 2016 — Public concerns about Zika have triggered scientists to write a new Extension document to explain the virus. Meanwhile, state mosquito control agencies and the Florida Department of Health monitor ... read more

Feb. 10, 2016 — Newly patented compounds show significant improvements over existing treatments, showing low toxicity and, consequently, fewer side-effects. Infectious tropical diseases mainly affect people living ... read more

Feb. 9, 2016 — The first robotically driven experimentation system to determine the effects of a large number of drugs on many proteins, reducing the number of necessary experiments by 70 percent, has been created ... read more

Injury Deaths, Life-Expectancy Gap Between US and Other High-Income Countries

Feb. 9, 2016 — The contribution of three causes of injury death to the gap in life expectancy between the United States and 12 comparable countries in 2012 has been estimated in a new study. The researchers focused ... read more

Study Shows Promising Safety Results for Anti-Aging Drug

Feb. 9, 2016 — Minimal metabolic side effects have been documented after continuous, long-term treatment with encapsulated rapamycin in a marmoset (monkey) model. Results lead to new research grant to study ... read more

Renal Denervation Helps to Bring Drug-Resistant Hypertension Under Control, Rat Study Shows

Feb. 9, 2016 — Most clinical studies have shown that renal denervation—a procedure that disrupts the nerves in the kidneys and prevents them from relaying signals—can treat drug-resistant hypertension, although ... read more

Some Heart Drugs, Antibiotics Show Effective in Fighting Cancer

Feb. 9, 2016 — Drugs that showed promising perspectives in treating cancers have been identified by researchers, according to a recent study. These drugs are normally used to treat other diseases, such as heart ... read more

Feb. 9, 2016 — In contrast to enduring stories about extraordinarily high rates of alcohol misuse among Native Americans, researchers have found that Native Americans' binge and heavy drinking rates actually ... read more

Conversion of Head and Neck Cancer Cells Into Radiation-Resistant Cancer Stem Cells Depends on HPV Status, Study Finds

Feb. 9, 2016 — Head and neck cancers that test positive for the human papilloma virus (HPV) are known to respond more favorably to radiation therapy than those that test HPV-negative, but an explanation for these ... read more

Device Hits Pancreatic Tumors Hard With Toxic 4-Drug Cocktail, Sparing the Body

Feb. 8, 2016 — An implantable device can deliver a particularly toxic cocktail of drugs directly to pancreatic tumors to stunt their growth or in some cases, shrink them -- all while showing signs that the rest of ... read more

Diabetes Drug Shown to Help Body Rebuild After Heart Attack

Feb. 8, 2016 — New light has been shed on how a common diabetes drug can be used to aid recovery from a heart attack. Metformin is a cost-efficient drug usually used as a first-line treatment in Type 2 diabetes as ... read more

Newer Pain Management Strategies Can Lead to Quicker, Shorter Recovery After Total Knee Replacement

Feb. 8, 2016 — According to a new literature review , a team-based care approach (consisting of the patient, family members, the orthopaedic surgeon and other medical practitioners) on total knee replacement (TKR) ... read more

Feb. 8, 2016 — A team led by engineers has 3-D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and ... read more

Feb. 8, 2016 — Using a model blood vessel system built on a polymer microchip, researchers have shown that the relative softness of white blood cells determines whether they remain in a dormant state along vessel ... read more

Gut Environment Could Reduce Severity of Malaria

Feb. 8, 2016 — Microorganisms in the gut could play a role in reducing the severity of malaria, according to a new study. Malaria is a mosquito-borne disease, and those with the illness often experience fever, ... read more

Restricting Ketamine Would Have 'Dire Consequences' for Surgery in Low-Resource Countries, Anesthesiologists Warn

Feb. 8, 2016 — Proposals to restrict access to ketamine by making it a "Schedule I" drug would have a major impact on the availability of anesthesia and surgery in low- to middle-income countries ... read more

Using Medical Marijuana to Stop Seizures in Kids

Feb. 8, 2016 — Desperate for relief, parents are taking unusual steps to help children plagued with seizures. The relief, however, comes in a most unlikely form: ... read more

Feb. 8, 2016 — An experimental nanoparticle therapy that combines low-density lipoproteins (LDL) and fish oil preferentially kills primary liver cancer cells without harming healthy cells, researchers ... read more

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