Featured Research

from universities, journals, and other organizations

New, more accurate way of imaging lung cancer tumors

Date:
May 2, 2013
Source:
Moffitt Cancer Center
Summary:
Scientists have devised a new computational method for assessing lung cancer tumors using CT, PET or MRI diagnostic technologies. The method, called single click ensemble segmentation (SCES), uses a new computer algorithm developed by the researchers to help segment and extract features of a tumor. The new approach not only improves diagnosis and prognosis assessments, but also saves time and health care dollars.

Moffitt Cancer Center and the University of South Florida have collaborated with researchers in China, the United Kingdom, the Netherlands and Germany to devise a new computational method for assessing lung cancer tumors using CT, PET or MRI diagnostic technologies. The method, called single click ensemble segmentation (SCES), uses a new computer algorithm developed by the researchers to help segment and extract features of a tumor. The new approach not only improves diagnosis and prognosis assessments, but also saves time and health care dollars.

Their study appeared in the March issue of Pattern Recognition.

Lung cancer is the deadliest cancer in men and women. According to the National Institutes of Health, the five-year survival rate (16.3 percent) is worse than many other cancers, such as colon (65.2 percent), breast (90.0 percent) and prostate (99.9 percent). More accurate tumor imaging, in terms of tumor feature extraction, could improve diagnostic and predictive accuracy

“The new method we developed will improve diagnostic accuracy and make more individualized cancer care possible,” said study senior author Robert J. Gillies, Ph.D., chair of the Department of Cancer Imaging and Metabolism at Moffitt. “It will improve our ability to quantify changes in cancer and respond appropriately with therapy.”

Tumor segmentation was previously a difficult task because of the diverse composition of cancer lesions when compared to normal tissues. The new segmentation method marks a great improvement over a previously used manual method, said the researchers.

“A common approach to delineate lung cancer tumors is for the radiologist or radiation oncologist to manually draw the boundary of the tumor,” explained Gillies. “This method is variable and operator-dependent. A highly automatic, accurate and reproducible lung tumor delineation algorithm would offer a significant advance.”

Their development of SCES offers that advancement, and because the process is automated, it requires less time and effort.

“A big advantage with single click ensemble segmentation is that it only requires one human interaction – the manual seed input. This is when the radiologist or radiation oncologist places the seed points in the tumor area,” Gillies said. “With SCES, lesion delineation was accurate and consistent, and the lung segmentations workload was greatly reduced.”

The new algorithm uses the original by incorporating the original seed point to define an area within which multiple seed points are automatically generated. Ensemble segmentation can then be obtained from the multiple regions.

According to the researchers, the measurement can be used to determine if the tumor is increasing or decreasing in size, as well as describe features such as shape and texture.

“With this method, all the radiologist has to do is click their mouse on a tumor and the program will automatically perform an accurate measurement,” explained Hall. “We also demonstrated that this approach reduces inter-observer variability with significantly fewer operator interactions when compared with the original algorithm.”

The capabilities of the new algorithm were successfully tested on a large patient tumor imaging data set.

Their work was funded by National Institutes of Health Grant 1U01 CA 143062-01


Story Source:

The above story is based on materials provided by Moffitt Cancer Center. Note: Materials may be edited for content and length.


Cite This Page:

Moffitt Cancer Center. "New, more accurate way of imaging lung cancer tumors." ScienceDaily. ScienceDaily, 2 May 2013. <www.sciencedaily.com/releases/2013/05/130502115527.htm>.
Moffitt Cancer Center. (2013, May 2). New, more accurate way of imaging lung cancer tumors. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2013/05/130502115527.htm
Moffitt Cancer Center. "New, more accurate way of imaging lung cancer tumors." ScienceDaily. www.sciencedaily.com/releases/2013/05/130502115527.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins