Featured Research

from universities, journals, and other organizations

Use Of Novel Antipsychotic Shows Decreased Rehospitalization Rates, Lower Cost

Date:
December 12, 1997
Source:
University Of Maryland At Baltimore
Summary:
New findings by researchers from the University of Maryland show that patients treated with lower doses of the novel antipsychotic risperidone were rehospitalized less frequently than patients who received conventional antipsychotic treatment, thereby improving results and lowering costs.

Long-term outcomes for patients with schizophrenia have been disappointing. Treatment using conventional antipsychotics show high rates of recidivism which, in turn, is costly for the system. However, new findings by researchers from the University of Maryland show that patients treated with the novel antipsychotic risperidone (brand name Risperdalฎ) experienced a lower readmission rate than patients who received conventional antipsychotic treatment.

Related Articles


The study team, lead by Dr. Robert Conley, assistant professor of psychiatry at the University of Maryland School of Medicine, along with Dr. Raymond Love, director of the Mental Health Program at the University of Maryland School of Pharmacy, and Dr. Deanna Kelly, instructor at the School of Medicine, found that after one year, the rehospitalization rate for patients treated with risperidone for schizophrenia or schizoaffective disorder was 17 percent, which compares favorably to previously published rates of as high as 50 percent using conventional antipsychotics.

"This study shows that in a real-world setting, the benefits of novel antipsychotics include improvements in the patients’ quality of life and potential monetary savings," said Conley. "This evidence suggests that the higher cost of these novel agents can be made up for in terms of dollar savings from fewer readmissions."

In a separate but related study, Dr. Conley’s team analyzed risperidone dosing trends in schizophrenia patients within the Maryland Mental Health System between 1994 and 1996, the first such study in a large population. They determined that patients successfully discharged on risperidone were treated with significantly lower doses than those who remained hospitalized.

"The importance of establishing effective dosing regimens cannot be overstated," said Conley. "Patients who are under dosed or who receive excessive doses may fail to respond or could experience negative side-effects, which, in turn, could lead to drug discontinuation by clinicians or noncompliance by patients. Higher doses also may mean higher costs."

Love pointed out that another benefit of using lower doses of risperidone may be a decrease in costs per patient treated. In 1996, the cost for a patient receiving the average discharge dose of risperidone was approximately $1,900 compared to $2,450 for a patient receiving the average dose reported for those who remained hospitalized. Recent reports from Maryland’s Statewide Pharmacy and Therapeutics Committee show that the average daily dose of the antipsychotic olanzapine (brand name Zyprexaฎ) was $3,350 for discharged patients and $4,000 for those who remained hospitalized.

"Although the availability of a newer generation of antipsychotics has resulted in savings by reducing hospitalization, the higher costs of these medications may offset some of those savings," said Love. "This study shows that at least for risperidone, use of lower doses may produce better outcomes as well as reduce costs."


Story Source:

The above story is based on materials provided by University Of Maryland At Baltimore. Note: Materials may be edited for content and length.


Cite This Page:

University Of Maryland At Baltimore. "Use Of Novel Antipsychotic Shows Decreased Rehospitalization Rates, Lower Cost." ScienceDaily. ScienceDaily, 12 December 1997. <www.sciencedaily.com/releases/1997/12/971212094857.htm>.
University Of Maryland At Baltimore. (1997, December 12). Use Of Novel Antipsychotic Shows Decreased Rehospitalization Rates, Lower Cost. ScienceDaily. Retrieved April 24, 2015 from www.sciencedaily.com/releases/1997/12/971212094857.htm
University Of Maryland At Baltimore. "Use Of Novel Antipsychotic Shows Decreased Rehospitalization Rates, Lower Cost." ScienceDaily. www.sciencedaily.com/releases/1997/12/971212094857.htm (accessed April 24, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, April 24, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

85 Killed in Niger by Meningitis Since Start of Year

85 Killed in Niger by Meningitis Since Start of Year

AFP (Apr. 24, 2015) — A meningitis outbreak in Niger has killed 85 people since the start of the year prompting authorities to close schools in the capital Niamey until Monday. Video provided by AFP
Powered by NewsLook.com
C-Section Births a Trend in Brazil

C-Section Births a Trend in Brazil

AFP (Apr. 24, 2015) — More than half of Brazil&apos;s babies are born via cesarean section, as mothers and doctors opt for a faster and less painful experience despite the health risks. Duration: 02:02 Video provided by AFP
Powered by NewsLook.com
Anti-Malaria Jab Hope

Anti-Malaria Jab Hope

Reuters - News Video Online (Apr. 24, 2015) — The world&apos;s first anti-malaria vaccine could get the go-ahead for use in Africa from October if approved by international regulators. Paul Chapman reports. Video provided by Reuters
Powered by NewsLook.com
3D Food Printing: The Meal of the Future?

3D Food Printing: The Meal of the Future?

AP (Apr. 23, 2015) — Developers of 3D food printing hope the culinary technology will revolutionize the way we cook and eat. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins