Featured Research

from universities, journals, and other organizations

Depression A Risk Factor For Coronary Artery Disease In Men

Date:
July 15, 1998
Source:
Johns Hopkins Medical Institutions
Summary:
Men with clinical depression are more than twice as likely to develop coronary artery disease (CAD) as their non-depressed counterparts, a Johns Hopkins study has shown.

The Head-Heart Connection

Men with clinical depression are more than twice as likely to develop coronary artery disease (CAD) as their non-depressed counterparts, a Johns Hopkins study has shown.

"Clinical depression appears to be an independent risk factor for coronary artery disease, even several decades after the first episode," says Daniel E. Ford, M.D., M.P.H., lead author of the study and an associate professor of medicine, epidemiology and health policy and management at Hopkins. "When we accounted for traditional risk factors for CAD, such as high cholesterol, cigarette smoking, hypertension and diabetes, depression remained a statistically significant cause."

Results of the study, supported by the National Institute of Aging, were published in the July 13 issue of the Archives of Internal Medicine.

Ford and his colleagues analyzed data from the Johns Hopkins Precursors Study, a long-term investigation of 1,190 male medical students who were enrolled at Hopkins between 1948 and 1964 and who continue to be followed. In medical school and through the follow-up period, information on family history, health behaviors and clinical depression was collected.

After 40 years of follow-up, 12 percent of the former students reported suffering at least one episode of clinical depression. Those who reported clinical depression were 2.12 times more likely to develop coronary artery disease or suffer a heart attack than their non-depressed counterparts. On average, symptoms of CAD appeared about 15 years after the first episode of depression.

The men who developed clinical depression drank more coffee at the study's outset than those who did not but did not differ from their counterparts in terms of blood pressure, cholesterol, cigarette smoking, physical activity, obesity or family history of CAD.

A minority (23 percent) reported no treatment for clinical depression, with 33 percent reporting use of antidepressant medications and 44 percent reporting psychotherapy with or without use of benzodiazepines or other sedatives. Treatment for depression did not necessarily lower the men's risk of developing CAD, Ford says, but those who were treated may have been more severely depressed initially.

During follow-up, participants with clinical depression were more likely to continue smoking, but this did not account for the increased risk of CAD. For the small number of women in the study, clinical depression also was a risk factor for CAD.

The study's other authors were Lucy A. Mead, Sc.M.; Patricia P. Chang, M.D.; Lisa Cooper-Patrick, M.D., M.P.H.; Nae-Yuh Wang, M.S.; and Michael J. Klag, M.D., M.P.H. All faculty members of The Johns Hopkins University schools of Medicine or Public Health, they work together in Hopkins' Welch Center for Prevention, Epidemiology and Clinical Research.

###Johns Hopkins Medical Institutions' news releases are available on a PRE-EMBARGOED basis on EurekAlert at http://www.eurekalert.org, Newswise at http://www.newswise.com and from the Office of Communications and Public Affairs' direct e-mail news release service. To enroll, call 410-955-4288 or send e-mail to bsimpkin@welchlink.welch.jhu.edu.

On a POST-EMBARGOED basis find them at http://hopkins.med.jhu.edu, Quadnet at http://www.quad-net.com and ScienceDaily at http://www.sciencedaily.com.


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Depression A Risk Factor For Coronary Artery Disease In Men." ScienceDaily. ScienceDaily, 15 July 1998. <www.sciencedaily.com/releases/1998/07/980715083720.htm>.
Johns Hopkins Medical Institutions. (1998, July 15). Depression A Risk Factor For Coronary Artery Disease In Men. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/1998/07/980715083720.htm
Johns Hopkins Medical Institutions. "Depression A Risk Factor For Coronary Artery Disease In Men." ScienceDaily. www.sciencedaily.com/releases/1998/07/980715083720.htm (accessed September 30, 2014).

Share This



More Mind & Brain News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Do Video Games Trump Brain Training For Cognitive Boosts?

Do Video Games Trump Brain Training For Cognitive Boosts?

Newsy (Sep. 29, 2014) More and more studies are showing positive benefits to playing video games, but the jury is still out on brain training programs. Video provided by Newsy
Powered by NewsLook.com
Your Spouse's Personality May Influence Your Earnings

Your Spouse's Personality May Influence Your Earnings

Newsy (Sep. 26, 2014) Research from Washington University suggest people with conscientious spouses have greater career success. Video provided by Newsy
Powered by NewsLook.com
Can A Blood Test Predict Psychosis Risk?

Can A Blood Test Predict Psychosis Risk?

Newsy (Sep. 26, 2014) Researchers say certain markers in the blood can predict risk of psychosis later in the life. The test can aid in early treatment for the condition. Video provided by Newsy
Powered by NewsLook.com
Harpist Soothes Gorillas, Orangutans With Music

Harpist Soothes Gorillas, Orangutans With Music

AP (Sep. 25, 2014) Teri Tacheny, a harpist, has a loyal following of fans who appreciate her soothing music. Every month, gorillas, orangutans and monkeys amble down to hear her play at the Como Park Zoo in Minnesota. (Sept. 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins