Featured Research

from universities, journals, and other organizations

Researchers At Cedars-Sinai Medical Center Participate In Study To Assess Effects Of Soy-Based Supplement On Symptoms Of Menopause

Date:
November 2, 1999
Source:
Cedars-Sinai Medical Center
Summary:
Scientists at Cedars-Sinai Medical Center are seeking women who experience "hot flushes" and other symptoms associated with the onset of menopause. The medical center's Center for Women's Health is one of about 17 sites nationwide conducting a clinical study of the ability of soy-based "phytoestrogens" to moderate the unpleasant symptoms many women experience as their menstrual cycles become less regular.

LOS ANGELES (October 28, 1999) - Scientists at Cedars-Sinai Medical Center are seeking women who experience "hot flushes" and other symptoms associated with the onset of menopause.

The medical center's Center for Women's Health is one of about 17 sites nationwide conducting a clinical study of the ability of soy-based "phytoestrogens" to moderate the unpleasant symptoms many women experience as their menstrual cycles become less regular.

Phytoestrogens, compounds that exist in many plants that are used for food, mimic the effects of the hormone estrogen. As women near menopause, production of their natural estrogen declines, resulting in a variety of symptoms, including insomnia, vaginal dryness, mood swings, night sweats and hot flushes - a sense of warmth that begins on the face and radiates to the neck and chest.

These symptoms often are treated with estrogen replacement therapy but increased levels of estrogen can result in an overgrowth of the cells of the endometrium - the lining of the uterus - and this condition is a known risk factor for the later development of endometrial cancer. The effects of estrogen are sometimes controlled by the addition of progestin, another hormone. But progestin can bring about other unpleasant side effects, such as menstrual-like bleeding.

It appears that phytoestrogens may be helpful in the treatment of menopausal symptoms without these side effects, although the amount of benefit has varied in previous clinical trials. Soybeans, chickpeas, lentils, clovers and certain other plants have high concentrations of a specific type of phytoestrogen called isoflavones. The soy-based phytoestrogen being tested is already on the market as an over-the-counter supplement but two new dosage levels are now being studied.

Elaine S. Revis, a research scientist at the Center for Women's Health who has a doctoral degree in clinical psychology, said the study will provide general evaluations of "quality of life issues" - such as mood, sexual functioning, and outlook - although the focus is on "vasomotor symptoms," or hot flushes, which are often referred to as hot flashes.

"Hot 'flashes' is clearly the term that most people are comfortable with, although 'flushes' is more technically correct," she said. "It is what actually happens. Women get a vasomotor flush, a dilation of blood vessels. The result is a hot sensation and a red flush in skin color."

Scientists have in recent years begun to evaluate the role of phytoestrogens in the diet. It has been noted, for example, that the prevalence of menopausal symptoms seems to be lower in some parts of the world in which the diet is high in phytoestrogens.

"We know that estrogen levels get very unstable as women approach menopause," said Dr. Revis. "As they go up and down, hot flushes and other symptoms occur. The supplementation of soy-based phytoestrogens is intended to help stabilize those hormonal levels."

Women interested in participating in the four-month study may contact Dr. Revis at 310-423-0526 for details.

# # #

For media information and to arrange an interview, please e-mail sandy@vancommunications.com or call 1-800-396-1002.


Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Researchers At Cedars-Sinai Medical Center Participate In Study To Assess Effects Of Soy-Based Supplement On Symptoms Of Menopause." ScienceDaily. ScienceDaily, 2 November 1999. <www.sciencedaily.com/releases/1999/11/991101153327.htm>.
Cedars-Sinai Medical Center. (1999, November 2). Researchers At Cedars-Sinai Medical Center Participate In Study To Assess Effects Of Soy-Based Supplement On Symptoms Of Menopause. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/1999/11/991101153327.htm
Cedars-Sinai Medical Center. "Researchers At Cedars-Sinai Medical Center Participate In Study To Assess Effects Of Soy-Based Supplement On Symptoms Of Menopause." ScienceDaily. www.sciencedaily.com/releases/1999/11/991101153327.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com
Raw: Elephant Undergoes Surgery in Tbilisi Zoo

Raw: Elephant Undergoes Surgery in Tbilisi Zoo

AP (Sep. 18, 2014) Grand the elephant has successfully undergone surgery to remove a portion of infected tusk at Tbilisi Zoo in Georgia. British veterinary surgeons used an electric drill to extract the infected piece. (Sept. 18) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins