Featured Research

from universities, journals, and other organizations

Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease

Date:
September 4, 2000
Source:
University Of Maine
Summary:
Strong evidence that cognitive tests may be useful for signaling Alzheimer’s Disease years before other symptoms appear has been reported by Merrill F. "Pete" Elias, UMaine professor of psychology, and colleagues in the June issue of the Archives of Neurology.

ORONO, Maine -- Strong evidence that cognitive tests may be useful for signaling Alzheimer’s Disease years before other symptoms appear has been reported by Merrill F. "Pete" Elias, UMaine professor of psychology, and colleagues in the June issue of the Archives of Neurology. While earlier studies have reached the same conclusion, the new report expands it with a larger group of subjects followed over a longer period of time.

Elias and his colleagues based their findings on an analysis of cognitive tests given to 1,076 participants in the Framingham Heart Study. Between 1975 and 1979, neuropsychologists administered a battery of tests measuring new learning and immediate recall, visual reproduction from memory, verbal associations and abstract reasoning and other functions.

All subjects were free of Alzheimer’s Disease, other forms of dementia and stroke at the initial baseline test. They were then neurologically assessed for Alzheimer’s Disease for the next 22 years. Lower test performance at the baseline testing was associated with development of Alzheimer’s at some time during that 22-year follow-up period. Lowered retention for verbal material and lower abstract reasoning at baseline were the strongest predictors of the disease.

Collaborating on the study were Alexa Beiser, Philip A. Wolf, Rhoda Au, and Ralph B. D’Augostino, all of Boston University, and Roberta F. White of the Boston Department of Veterans Affairs and Odense University in Denmark.

The research was supported by grants from the National Institute on Aging and the National Heart, Lung and Blood Institute of the National Institutes of Health.

The results suggest that a pre-clinical phase of Alzheimer’s Disease can precede the appearance of the disease by many years and that this phase can be detected by appropriate neuropsychological tests.

In an editorial in the same issue of the journal, Richard Mayeux of Columbia University notes that "the investigation by Elias et al has extremely important implications for those developing treatments for AD and for those investigating its cause."

He emphasizes that the report does not distinguish between factors that may pre-dispose an individual to Alzheimer’s and physiological changes in the brain. Moreover, not all older adults who suffer memory loss progress to dementia or Alzheimer’s Disease.

-30-

Contact: Merrill F. "Pete" Elias, Dept. of Psychology, 207-244-9674, mfelias@aol.com

Nick Houtman, Dept. of Public Affairs, 207-581-3777, houtman@maine.edu

Note: This and other science news can be seen on the MaineSci web site, http://www.umaine.edu/mainesci.


Story Source:

The above story is based on materials provided by University Of Maine. Note: Materials may be edited for content and length.


Cite This Page:

University Of Maine. "Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease." ScienceDaily. ScienceDaily, 4 September 2000. <www.sciencedaily.com/releases/2000/07/000720092258.htm>.
University Of Maine. (2000, September 4). Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2000/07/000720092258.htm
University Of Maine. "Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease." ScienceDaily. www.sciencedaily.com/releases/2000/07/000720092258.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins