Featured Research

from universities, journals, and other organizations

Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease

Date:
September 4, 2000
Source:
University Of Maine
Summary:
Strong evidence that cognitive tests may be useful for signaling Alzheimer’s Disease years before other symptoms appear has been reported by Merrill F. "Pete" Elias, UMaine professor of psychology, and colleagues in the June issue of the Archives of Neurology.

ORONO, Maine -- Strong evidence that cognitive tests may be useful for signaling Alzheimer’s Disease years before other symptoms appear has been reported by Merrill F. "Pete" Elias, UMaine professor of psychology, and colleagues in the June issue of the Archives of Neurology. While earlier studies have reached the same conclusion, the new report expands it with a larger group of subjects followed over a longer period of time.

Elias and his colleagues based their findings on an analysis of cognitive tests given to 1,076 participants in the Framingham Heart Study. Between 1975 and 1979, neuropsychologists administered a battery of tests measuring new learning and immediate recall, visual reproduction from memory, verbal associations and abstract reasoning and other functions.

All subjects were free of Alzheimer’s Disease, other forms of dementia and stroke at the initial baseline test. They were then neurologically assessed for Alzheimer’s Disease for the next 22 years. Lower test performance at the baseline testing was associated with development of Alzheimer’s at some time during that 22-year follow-up period. Lowered retention for verbal material and lower abstract reasoning at baseline were the strongest predictors of the disease.

Collaborating on the study were Alexa Beiser, Philip A. Wolf, Rhoda Au, and Ralph B. D’Augostino, all of Boston University, and Roberta F. White of the Boston Department of Veterans Affairs and Odense University in Denmark.

The research was supported by grants from the National Institute on Aging and the National Heart, Lung and Blood Institute of the National Institutes of Health.

The results suggest that a pre-clinical phase of Alzheimer’s Disease can precede the appearance of the disease by many years and that this phase can be detected by appropriate neuropsychological tests.

In an editorial in the same issue of the journal, Richard Mayeux of Columbia University notes that "the investigation by Elias et al has extremely important implications for those developing treatments for AD and for those investigating its cause."

He emphasizes that the report does not distinguish between factors that may pre-dispose an individual to Alzheimer’s and physiological changes in the brain. Moreover, not all older adults who suffer memory loss progress to dementia or Alzheimer’s Disease.

-30-

Contact: Merrill F. "Pete" Elias, Dept. of Psychology, 207-244-9674, mfelias@aol.com

Nick Houtman, Dept. of Public Affairs, 207-581-3777, houtman@maine.edu

Note: This and other science news can be seen on the MaineSci web site, http://www.umaine.edu/mainesci.


Story Source:

The above story is based on materials provided by University Of Maine. Note: Materials may be edited for content and length.


Cite This Page:

University Of Maine. "Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease." ScienceDaily. ScienceDaily, 4 September 2000. <www.sciencedaily.com/releases/2000/07/000720092258.htm>.
University Of Maine. (2000, September 4). Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2000/07/000720092258.htm
University Of Maine. "Lower Cognitive Performance Linked to Later Diagnosis Of Alzheimer’s Disease." ScienceDaily. www.sciencedaily.com/releases/2000/07/000720092258.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins