Featured Research

from universities, journals, and other organizations

Study Suggests Diabetics Can Use Light To Measure Glucose

Date:
July 26, 2000
Source:
Ohio University
Summary:
Scientists at Ohio University and the University of Iowa have edged one step closer to the development of a glucose measuring device that uses light instead of a blood sample. Such a diagnostic tool would offer millions of diabetics a painless option for keeping their disease in check.

Contacts: Gary Small, Ohio University, (740) 593-1748; [email protected]

Related Articles


Mark Arnold, University of Iowa (319) 335-1368; [email protected]

ATHENS, Ohio – Scientists have edged one step closer to the development of a glucose measuring device that uses light instead of a blood sample. Sucha diagnostic tool would offer millions of diabetics a painless option forkeeping their disease in check.

People with diabetes must diligently monitor the amount of glucose intheir blood, which requires patients to apply needles to fingertips asoften as a half-dozen times a day. The routine is painful and inconvenient,two factors doctors say often deter healthy maintenance of the disease.

But a new study by chemists at Ohio University and the University of Iowasuggests that a technique that passes infrared light through the skin canaccurately measure blood glucose, research that one day could eliminate theneed for a blood sample test.

"Most people feel that if you have a test that is noninvasive, diabeticswould use it more often and probably do a better job of managing theirdisease," says Gary Small, a professor of chemistry at Ohio University whoco-authored the new study with Mark Arnold, professor of chemistry at theUniversity of Iowa. The research appears in the latest issue of the journalDiabetes Technology and Therapeutics.

In a small clinical trial involving five people with Type I, orinsulin-dependent, diabetes, researchers used light to measure bloodglucose up to six times a day for 39 days. Researchers shot a beam ofinfrared light through the tongue, which has a good blood supply.

Glucose and other molecules in the blood absorb specific frequencies oflight. As the researchers couldn't see this happening in the tissue, theyanalyzed the light emerging from the tongue. By measuring the degree towhich each light frequency was absorbed by the tongue, the researchers wereable to determine how much glucose was in the blood.

Although the apparatus designed for these studies is expensive andimpractical for home use, researchers envision a light-based glucosemonitor that would be about the size of a portable CD player and probablycost around $500. Ohio University and the University of Iowa share two U.S.patents on the data analysis techniques used in the researchers' studies,including a method that would allow the instrument used in the clinicaltrials to be simplified and made potentially cheaper, smaller and morerugged. But the target of such a commercial device wouldn't be the tongue.

"The tongue makes a great place for measuring glucose in our tests, but aterrible place for a home monitor," Arnold says. "Eventually, we'd want tobe able to make the measurements on a fingertip or ear lobe."

This isn't the first study to suggest infrared light can be used tomeasure blood glucose. Other researchers have presented data that suggestedthe theory had merit. But a 1998 article by Small and Arnold in the journalAnalytical Chemistry argued that those earlier studies were done on tissuetoo thin to contain enough glucose for an accurate reading. The paper alsoquestioned the credibility of previous experimental protocols. Anycorrelation between the amount of infrared light detected through tissueand glucose levels, they argued, was coincidental.

"Our new findings represent what we feel is the first comprehensivedemonstration that noninvasive measurements can be made with infraredlight," Small says.

Now that they know the technique works, the research team plans to improvethe performance of the method. Small estimates the technique could be readyfor commercial use in three to five years.

The research was also co-authored by Jason Burmeister at the University ofIowa and was supported by the National Institutes of Health and InvernessMedical Technology. Small holds an appointment in the College of Arts andSciences.

- 30 -

Written by Kelli Whitlock.


Story Source:

The above story is based on materials provided by Ohio University. Note: Materials may be edited for content and length.


Cite This Page:

Ohio University. "Study Suggests Diabetics Can Use Light To Measure Glucose." ScienceDaily. ScienceDaily, 26 July 2000. <www.sciencedaily.com/releases/2000/07/000724094958.htm>.
Ohio University. (2000, July 26). Study Suggests Diabetics Can Use Light To Measure Glucose. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2000/07/000724094958.htm
Ohio University. "Study Suggests Diabetics Can Use Light To Measure Glucose." ScienceDaily. www.sciencedaily.com/releases/2000/07/000724094958.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins