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Transplanted Human Stem Cells Develop into Broad Range of Tissues, Persist over a Year in Research at The Children's Hospital of Philadelphia

Date:
November 1, 2000
Source:
The Children's Hospital of Philadelphia
Summary:
Adult human mesenchymal stem cells, taken from bone marrow, have been induced to develop into a wide range of normal tissue after transplantation into fetal sheep. The transplanted cells have persisted over a year without immune system rejection, in research with potential implications for tissue engineering in diseases such as muscular dystrophy.

Philadelphia, Pa. — Adult human stem cells taken from bone marrow have been induced to develop into a wide range of normal tissues, including bone, cartilage, fat, tendon and muscle, when transplanted into fetal sheep. The transplanted human cells have persisted in various sheep tissues for over one year without rejection by the sheep’s immune system. The study offers promise that in the future these cells may be useful for tissue repair or regeneration and for treatment of degenerative diseases such as muscular dystrophy.


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The above story is based on materials provided by The Children's Hospital of Philadelphia. Note: Materials may be edited for content and length.


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The Children's Hospital of Philadelphia. "Transplanted Human Stem Cells Develop into Broad Range of Tissues, Persist over a Year in Research at The Children's Hospital of Philadelphia." ScienceDaily. ScienceDaily, 1 November 2000. <www.sciencedaily.com/releases/2000/10/001030164628.htm>.
The Children's Hospital of Philadelphia. (2000, November 1). Transplanted Human Stem Cells Develop into Broad Range of Tissues, Persist over a Year in Research at The Children's Hospital of Philadelphia. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2000/10/001030164628.htm
The Children's Hospital of Philadelphia. "Transplanted Human Stem Cells Develop into Broad Range of Tissues, Persist over a Year in Research at The Children's Hospital of Philadelphia." ScienceDaily. www.sciencedaily.com/releases/2000/10/001030164628.htm (accessed April 19, 2014).

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