Leukemia News
May 3, 2015

Latest Headlines
updated 2:52pm EDT

More Leukemia News
May 3, 2015

Mar. 30, 2015 — A new drug that shows potential in laboratory studies against a rare type of acute leukemia has been developed by scientists. And additional studies suggest the same compound could play a role in ... read more

Researchers Effectively, Safely Overcome Radiation Resistance in Leukemia With an Engineered Precision Medicine

Mar. 26, 2015 — Improved survival rates have been demonstrated in mouse models of aggressive human leukemia using leukemia cells taken directly from patients, according to a new ... read more

Like Angelina Jolie, Study Pinpoints Genetic Cause of Increased Leukemia Risk

Mar. 25, 2015 — A newly-discovered, heritable genetic cause of acute lymphoblastic leukemia (ALL), namely mutation of the gene ETV6, has been discovered by researchers. "These people are born with a broken gene ... read more

Genetic Origins of Myelodysplastic Syndrome Discovered Using Stem Cells

Mar. 25, 2015 — Induced pluripotent stem cells (iPSCs) -- adult cells reprogrammed back to an embryonic stem cell-like state--may better model the genetic contributions to each patient's particular disease. In ... read more

Promising Drug a 'New Paradigm' for Treating Leukemia

Mar. 25, 2015 — A compound that delays leukemia in mice and effectively kills leukemia cells in human tissue samples has been developed by researchers, raising hopes that the drug could lead to improved treatments ... read more

Mar. 25, 2015 — Leukemia cells from patients suffering from chronic myeloid leukemia, especially in the advanced stage, lack one of the proteins: the famous BRCA1. Importantly, the protein is not present even if the ... read more

Enzyme Discovered That Keeps Blood Stem Cells Functional to Prevent Anemia

Mar. 23, 2015 — Stem cells can generate any type of cell in the body, but they are inactive most of the time—and for good reason. When stem cells become too active and divide too often, they risk acquiring cell ... read more

Measuring Treatment Response Proves to Be a Powerful Tool for Guiding Leukemia Treatment

Mar. 20, 2015 — Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with ... read more

Scientists Trace Genomic Evolution of High-Risk Leukemia

Mar. 19, 2015 — By genomic sequencing of leukemia cells from relapsed patients at different stages, scientists have discovered key details of how acute lymphoblastic leukemia (ALL) cells mutate to survive ... read more

Microenvironment Provides Growth Factor for Metastasis

Mar. 17, 2015 — When a person has cancer that spreads to the bone and bone marrow, the tissue becomes increasingly fragile, often leading to increased bone resorption. In a surprising discovery, investigators ... read more

Genetically Engineered Immunotoxin Shows Early Promise in Patients With B-Cell Malignancies

Mar. 13, 2015 — DT2219, a new bispecific ligand-directed diphtheria toxin, was found to be safe and clinically effective in a small group of patients with relapsed/refractory B-cell malignancies, according to phase ... read more

Childhood Leukemia Study Reveals Disease Subtypes, New Treatment Option

Mar. 9, 2015 — A new study of acute lymphoblastic leukemia (ALL), a blood cancer that primarily affects young children, has revealed that the disease has two distinct subtypes, and provides preliminary evidence ... read more

Chromosomal Rearrangement Is Key to Progress Against Aggressive Infant Leukemia

Mar. 6, 2015 — A highly aggressive form of leukemia in infants has surprisingly few mutations beyond the chromosomal rearrangement that affects the MLL gene, researchers have found. The findings suggest that ... read more

Reasons for Ibrutinib Therapy Discontinuation in CLL

Feb. 27, 2015 — About 10 percent of patients with chronic lymphocytic leukemia discontinued therapy with the Bruton tyrosine kinase inhibitor drug ibrutinib because of disease progression during clinical trials, ... read more

Experts Warn of Stem Cell Underuse as Transplants Reach One Million Worldwide

Feb. 27, 2015 — Findings of a new reveal striking variations between countries and regions in the use of this lifesaving stem cell transplantation, and high unmet need due to a chronic shortage of resources and ... read more

New Approach to Assessing Effectiveness of Anti-Cancer Drugs

Feb. 27, 2015 — Scientists have a developed a new method to monitor the effect of anti-cancer drugs on very rare leukemia stem cells. The approach potentially allows doctors to screen patients and personalize their ... read more

Leukemia-Associated Mutations Almost Inevitable as We Age

Feb. 26, 2015 — It's almost inevitable that we'll develop mutations associated with leukemia as we age, according to new research. These mutations are more common than previously thought and their numbers ... read more

Reasons for Ibrutinib Therapy Discontinuation in Patients With Chronic Lymphocytic Leukemia

Feb. 26, 2015 — About 10 percent of patients with chronic lymphocytic leukemia discontinued therapy with the Bruton tyrosine kinase inhibitor drug ibrutinib because of disease progression during clinical trials, ... read more

Feb. 24, 2015 — Researchers have identified the first genetic variation that is associated with increased risk and severity of peripheral neuropathy following treatment with a widely used anti-cancer drug. ... read more

Gene Variant, Risk, Severity of Nerve Disorder Linked to Cancer Drug

Feb. 24, 2015 — Children with acute lymphoblastic leukemia who had a certain gene variant experienced a higher incidence and severity of peripheral neuropathy after receiving treatment with the cancer drug ... read more

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