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On The Trail Of A Targeted Therapy For Blood Cancers
Researchers are examining a
family of blood proteins
that they hope holds a key
to decreasing the toxic
effects of chemotherapy in
children and adults. Their
... > full story
Bone Marrow Transplants: Cancer Drug Shows Promise Against Graft Vs. Host Disease
A study in mice suggests the
drug SAHA, a new antitumor
drug, is also able to reduce
the effects of
graft-versus-host disease, a
... > full story
Tumor-inhibiting Protein Could Be Effective In Treating Leukemia
Angiocidin, a
tumor-inhibiting novel
protein, may also have a
role as a new therapeutic
application in treating
... > full story
New Drug Combination Kills Leukemia Cells By Shutting Down Their Energy Source
Researchers have discovered
a drug combination that
kills leukemia cells by
shutting down their energy
source and hastening cell
... > full story
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Key Proteins In Blood Stem Cell Replication Pinpointed
October 11, 2008 — A discovery from Stanford researchers is the first to directly link the notorious members of the retinoblastoma family of proteins to the cellular production factories responsible for churning out ... > full story -
New Leukemia Signal Could Point Way To Better Treatment
September 18, 2008 — Cancer researchers have discovered a promising new chemotherapy target for a deadly form of leukemia. Their discovery hinges on a novel "double agent" role for a molecular signal that regulates cell ... > full story -
Embryonic Stem Cells Might Help Reduce Transplantation Rejection
September 17, 2008 — Researchers have shown that immune-defense cells influenced by embryonic stem cell-derived cells can help prevent the rejection of hearts transplanted into mice, all without the use of ... > full story -
Novel Clinical Study For Lymphoma Patients Beginning
September 2, 2008 — The Virginia Commonwealth University Massey Cancer Center recently opened a National Cancer Institute-sponsored, phase II clinical study for certain sub-types of non-Hodgkin's ... > full story -
Deletion Of Chromatin Remodeling Genes Leads To Leukemia In Mice
August 27, 2008 — Mice lacking both copies of the Arid4A gene and one copy of the Arid4B gene develop acute myeloid leukemia (AML) and may provide an important animal model for preleukemic and leukemic conditions, ... > full story -
Inhibitors Of The Molecule PI3K Throw One Form Of Leukemia A CurveB-ALL
August 26, 2008 — Some cases of a form of leukemia known as pre-B cell acute lymphoblastic leukemia (pre-B-ALL) are caused by a genetic event that leads to the generation of a rogue chromosome known as the ... > full story -
Enzyme New Potential Target In Treating Blood Cancer
August 24, 2008 — A discovery by researchers in Sweden may lead to new treatments for blood cancer and other diseases. By stopping the production of a specific enzyme, ICMT, researchers were able to alleviate disease ... > full story -
New Insights Into The Regulation Of PTEN Tumor Suppression Function
August 23, 2008 — New findings define a pathway that maintains PTEN in the nucleus and offer a novel target for enhancing this gene's tumor suppressive ... > full story -
Landmark Sickle Cell Disease Trial To Investigate Unrelated Donor Marrow And Umbilical Cord Blood Transplants
August 19, 2008 — More than 20 institutions are taking part in a first-ever Phase II clinical trial of unrelated donor marrow and umbilical cord blood transplants for severe sickle cell disease. If successful, the ... > full story -
Sequential Doxorubicin And Zoledronic Acid Have Powerful Anti-Tumor Effect In Vivo
August 15, 2008 — The use of doxorubicin followed by zoledronic acid reduced tumor size substantially in a mouse model of breast cancer that does not have bone ... > full story
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