Featured Research

from universities, journals, and other organizations

The Jury's Still Out On Soy

Date:
November 22, 2000
Source:
Mayo Clinic
Summary:
Despite studies that indicate benefits of soy isoflavones, a report published by Mayo Clinic physicians in the November edition of Mayo Clinic Proceedings finds insufficient data to draw any definitive conclusions in the use of soy isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women.

ROCHESTER, MINN -- Despite studies that indicate benefits of soy isoflavones, a report published by Mayo Clinic physicians in the November edition of Mayo Clinic Proceedings finds insufficient data to draw any definitive conclusions in the use of soy isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women.

Recent interest in natural products with specific health claims has increased interest in soy proteins and their potential estrogen-like effects. Soybeans are a staple in the diet of East Asian countries. In these areas with soy-enriched diets, epidemiological studies reveal lower incidences of hormone-dependent diseases such as breast and ovarian cancer along with coronary artery disease.

The soy phytoestrogens, specifically isoflavones, have been postulated to be partly responsible for this protection. As a result, there has been intense interest in the isoflavones as "substitutes" for estrogen for postmenopausal women.

Isoflavones have emerged as the most interesting class of phytoestrogens as they have potential estrogenic activity and an extensive range of biological actions.

The authors of the Mayo Clinic report looked at various studies about isoflavones and the effects they have on coronary artery disease, breast cancer prevention, bone loss, the central nervous system, the endometrium, hormonal effects, attenuation of hot flashes and the skin.

The authors concluded, "The data we have thus far are insufficient, and it is premature to draw definitive conclusions regarding the use of isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women. Appropriate dosage studies with the widely available isolated isoflavones have yet to be done. Long-term benefits of isoflavones with regard to fracture prevention, prevention of hormone-dependent cancers, attenuation of memory loss, and prevention of cardiovascular disease are currently unknown. Although epidemiological and basic laboratory studies allude to the possible protective effects of soy isoflavones on specific target tissues, randomized, placebo-controlled clinical trials are necessary to address these important issues."

To date, the article states, no adverse effects of short-or long-term use of soy proteins have been reported in humans. The only adverse effects known are reported in animals.

Mayo Clinic Proceedings is a peer-reviewed and indexed general/internal medicine journal, published for 75 years by Mayo Foundation, with a circulation of 120,000 nationally and internationally.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "The Jury's Still Out On Soy." ScienceDaily. ScienceDaily, 22 November 2000. <www.sciencedaily.com/releases/2000/11/001120074049.htm>.
Mayo Clinic. (2000, November 22). The Jury's Still Out On Soy. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2000/11/001120074049.htm
Mayo Clinic. "The Jury's Still Out On Soy." ScienceDaily. www.sciencedaily.com/releases/2000/11/001120074049.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins