Featured Research

from universities, journals, and other organizations

PBBs In Fire Retardant Associated With Early Menstruation In Michigan Girls Whose Mothers Were Exposed In 1973

Date:
December 14, 2000
Source:
NIH/National Institute Of Environmental Health Sciences
Summary:
Foods that were contaminated in Michigan in 1973, when a fire retardant containing the chemical polybrominated biphenyl PBB was accidentally mixed with animal feed, have been associated with an early onset of menstruation and pubic hair in some daughters of the women exposed, scientists reported in the journal Epidemiology.

Foods that were contaminated in Michigan in 1973, when a fire retardant containing the chemical polybrominated biphenyl PBB was accidentally mixed with animal feed, have been associated with an early onset of menstruation and pubic hair in some daughters of the women exposed, scientists reported in the journal Epidemiology (Nov. 2000, Vol. 11, No. 6.)

Related Articles


The daughters of the most highly exposed women began menstruation, on average, before they reached their twelfth birthdays.

The study by scientists at Emory University and the Centers for Disease Control and Prevention in Atlanta, and the Michigan Department of Community Health, was funded by the National Institute of Environmental Health Sciences, part of the National Institutes of Health, and by the U.S. Environmental Protection Agency's Office of Research and Development.

In 1973, a fire retardant containing PBBs, was mistakenly mixed with cattle feed in place of a feed additive. The contamination was eventually discovered when milk production went down and calves were stillborn or born with hoof deformities. By the time the source of the PBBs was identified, at least 4,000 people had been exposed through contaminated meat and dairy products. PBB accumulates in fatty tissue in the body and is stored for years.

In the current study, researchers contacted female offspring, 5 to 24 years of age, born after the Michigan PBB incident to mothers listed as exposed to PBB in the Michigan PBB registry. Those with earliest menstruation were daughters of mothers with the highest estimated serum levels of PBBs during pregnancy, who had also nursed their infant daughters, giving them both prenatal and breast milk exposures. In the PBB study, the most highly exposed girls were a year ahead in starting their periods, at 11.6 years compared to 12.7 years for less-exposed girls. "This study lends support to the hypothesis that events associated with puberty may be affected by pre- and postnatal exposure to PBB's," Michele Marcus, Ph.D., principal investigator of the study.

This is the second study to associate early puberty with exposure to a specific chemical. The first study, by Ivelisse Colon and co-authors, appearing in the NIEHS journal Environmental Health Perspectives in September (Vol. 108, Number 9) associated precocious puberty in young girls in Puerto Rico with the plasticizer chemicals called phthalates.

The largest study to date to determine the incidence of precocious puberty in the United States was published by Marcia Herman-Giddens in the journal Pediatrics in 1997, and with a sample size of 17,000 showed that 1 in every 7 Caucasian girls and 1 out of every 2 African American girls develop breasts or pubic hair before the age of 8. In the current study, the girls who were most highly exposed to PBBs had pubic hair at an earlier age than less-exposed girls. However there were no differences found in timing of breast development.


Story Source:

The above story is based on materials provided by NIH/National Institute Of Environmental Health Sciences. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute Of Environmental Health Sciences. "PBBs In Fire Retardant Associated With Early Menstruation In Michigan Girls Whose Mothers Were Exposed In 1973." ScienceDaily. ScienceDaily, 14 December 2000. <www.sciencedaily.com/releases/2000/12/001214082240.htm>.
NIH/National Institute Of Environmental Health Sciences. (2000, December 14). PBBs In Fire Retardant Associated With Early Menstruation In Michigan Girls Whose Mothers Were Exposed In 1973. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2000/12/001214082240.htm
NIH/National Institute Of Environmental Health Sciences. "PBBs In Fire Retardant Associated With Early Menstruation In Michigan Girls Whose Mothers Were Exposed In 1973." ScienceDaily. www.sciencedaily.com/releases/2000/12/001214082240.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins