Featured Research

from universities, journals, and other organizations

Dual Sensor Could Provide More Information, Earlier Warning For Diabetics

Date:
January 31, 2001
Source:
American Chemical Society
Summary:
Diabetics could benefit from data provided by a new device that monitors glucose and insulin levels simultaneously, allowing better management of the disease. In the laboratory, researchers created the electronic framework for a tiny sensor that could be implanted in the human body.

Diabetics could benefit from data provided by a new device that monitors glucose and insulin levels simultaneously, allowing better management of the disease. The findings are reported in the February 15 issue of Analytical Chemistry, a peer-reviewed journal of the American Chemical Society, the world's largest scientific society.

In the laboratory, researchers created the electronic framework for a tiny sensor that could be implanted in the human body. The first device of its kind to measure the glucose-insulin ratio, it could help predict changes leading to high or low blood sugar levels, according to Joseph Wang, an author of the paper and professor at New Mexico State University in Las Cruces, N.M.

Tracking insulin levels along with glucose could identify trends and concentrations sooner than is now possible, Wang said. Earlier warning of trouble signs could help diabetics stave off fatigue and more serious complications such as kidney failure and heart disease, he continued.

Insulin is the hormone that allows glucose (blood sugar) to enter cells and convert foods into energy to sustain life. When insulin fails to "unlock" cells, glucose builds up in the blood and cells die. Hazardous conditions can occur when blood contains either too little or too much glucose.

Glucose sensors and insulin pumps have been used for nearly a decade to measure and remedy imbalances in blood sugar levels. The sensor detects excess glucose while the pump acts as an artificial pancreas - the organ that produces insulin in the body. Another device known as an insulin detector estimates the amount of the hormone in the blood.

Combining two types of sensors in such a small device was a complicated task, Wang said. Glucose is measured in the milli-molar range, while insulin is tracked on even smaller nano-molar levels - a fivefold difference in magnitude. In addition, each must send an electrical signal without interference to a minicomputer that, ideally, can calculate, store and display information, he added.

"The nice thing is that this is two different concepts," Wang said. "Despite the fact that they are completely different principles, we have found that they can be integrated and work independently."

Employing methods similar to those used to create existing implants, the researchers designed a needle-shaped sensor that can be implanted in the body where it won't cause problems. The next step is testing the device in animals. The researchers hope to halve the size of the sensor, reducing it to the thickness of 26-gauge wire (about the size of a hypodermic needle).

More than 15 million people in the United States have diabetes and approximately 800,000 are diagnosed with the disease each year, according to the American Diabetes Association. Nearly 95 percent of those have type 2, or adult-onset, diabetes in which the body does not make enough, or properly use insulin. The rest have type 1 diabetes, in which the body produces no insulin; this necessitates daily insulin shots. Both forms of the life-threatening disease can cause blindness, nerve degeneration and stroke.

The research cited above was funded by a research grant from the National Institutes of Health.

Joseph Wang, Ph.D., is a professor in the department of chemistry and biochemistry at New Mexico State University in Las Cruces, N.M.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Dual Sensor Could Provide More Information, Earlier Warning For Diabetics." ScienceDaily. ScienceDaily, 31 January 2001. <www.sciencedaily.com/releases/2001/01/010131074731.htm>.
American Chemical Society. (2001, January 31). Dual Sensor Could Provide More Information, Earlier Warning For Diabetics. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2001/01/010131074731.htm
American Chemical Society. "Dual Sensor Could Provide More Information, Earlier Warning For Diabetics." ScienceDaily. www.sciencedaily.com/releases/2001/01/010131074731.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Fauci: Ebola Protocols to Focus on Training

Fauci: Ebola Protocols to Focus on Training

AP (Oct. 20, 2014) Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, says he expects revised CDC protocols on Ebola to focus on training, observation and ensuring health care workers are more protected. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins