Featured Research

from universities, journals, and other organizations

Argonne Researchers Create Powerful Stem Cells From Blood; May Revolutionize Medical Research And Transplantation

Date:
February 26, 2003
Source:
Argonne National Laboratory
Summary:
The particularly powerful – and very scarce – flexible forms of stem cells needed for medical research and treatment may now be both plentiful and simple to produce, with a new technology developed at the U.S. Department of Energy’s Argonne National Laboratory – and the source is as close as your own bloodstream.

The particularly powerful – and very scarce – flexible forms of stem cells needed for medical research and treatment may now be both plentiful and simple to produce, with a new technology developed at the U.S. Department of Energy’s Argonne National Laboratory – and the source is as close as your own bloodstream.

These flexible stem cells, able to morph into a variety of cell types, are called “pluripotent,” and before this Argonne research, they have been found only in fetal tissue, which is limited, and in bone marrow, which is difficult to collect. Pluripotent stem cells are important because they can generate all types of tissues found in the body, and the Argonne-developed technology can produce them from adult blood cells.

The finding may eventually offer researchers a practical alternative to the use of embryonic stem cells for research, drug discovery, and transplantation.

Argonne scientist Eliezer Huberman and his colleagues, Yong Zhao and David Greene, examined adult monocytes, a type of white blood cells that act as precursors to macrophages. The researchers found that when monocytes were exposed to a growth factor, they created a set of pluripotent stem cells. After cultivating the stem cells, the scientists were able to make the cells “differentiate” into nerve, liver, and immune system tissue by delivering more growth factors.

“Because of its great promise in medicine, I’m prouder of this work than of anything else I’ve done,” Huberman said.

The research is being published in the Proceedings of the National Academy of Sciences.

Storing the precursor cells in liquid nitrogen had no effect on their differentiation later. Because monocytes can be easily gathered from a patient's own blood supply, the researchers suggest that treating disease with a genetic match to prevent rejection may be possible in the future.

This means that the material should produce valuable candidates for transplantation therapy, useful to replenish immune cells that have been eradicated by cancer therapy or to replace neuronal tissue damaged during spinal cord injury, stroke, Alzheimer’s or Parkinson’s disease.

Funding for the research is from the National Institutes of Health. The researchers have applied for a patent on the new technology.

###

The nation’s first national laboratory, Argonne National Laboratory conducts basic and applied scientific research across a wide spectrum of disciplines, ranging from high-energy physics to climatology and biotechnology. The University of Chicago operates Argonne as part of the U.S. Department of Energy’s national laboratory system.


Story Source:

The above story is based on materials provided by Argonne National Laboratory. Note: Materials may be edited for content and length.


Cite This Page:

Argonne National Laboratory. "Argonne Researchers Create Powerful Stem Cells From Blood; May Revolutionize Medical Research And Transplantation." ScienceDaily. ScienceDaily, 26 February 2003. <www.sciencedaily.com/releases/2003/02/030225065929.htm>.
Argonne National Laboratory. (2003, February 26). Argonne Researchers Create Powerful Stem Cells From Blood; May Revolutionize Medical Research And Transplantation. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2003/02/030225065929.htm
Argonne National Laboratory. "Argonne Researchers Create Powerful Stem Cells From Blood; May Revolutionize Medical Research And Transplantation." ScienceDaily. www.sciencedaily.com/releases/2003/02/030225065929.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins