Featured Research

from universities, journals, and other organizations

Jefferson Neuroscientists Find Evidence Of Lead Exposure Affecting Recovery From Brain Injury

Date:
October 28, 2004
Source:
Thomas Jefferson University
Summary:
Lead exposure at a young age can hurt the brain’s development and cause learning and behavioral problems. It may also interfere with recovery from a brain injury. A new study by scientists at Jefferson Medical College shows that young rats exposed to low levels of lead take significantly longer to recover from a brain injury than those animals that weren’t lead-exposed.

Lead exposure at a young age can hurt the brain’s development and cause learning and behavioral problems. It may also interfere with recovery from a brain injury. A new study by scientists at Jefferson Medical College shows that young rats exposed to low levels of lead take significantly longer to recover from a brain injury than those animals that weren’t lead-exposed.

Related Articles


According to Jay Schneider, Ph.D., professor of pathology, anatomy and cell biology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, even low levels of lead exposure can have profound effects on the structure and function of the developing nervous system and cause attention, memory, learning, emotional and other behavioral problems that persist into adulthood.

Dr. Schneider says that it isn’t uncommon for children to have brain injuries. At the same time, the young brain is extremely “plastic,” and has a tremendous capacity to try to repair itself and recover. Yet, no one has looked at the effects of lead exposure early in life on the response of the brain to a later injury.

In an experiment, Dr. Schneider and his co-workers injured a specific part of the rat’s brain that controls the hind limbs in two groups of animals: one that had been exposed to lead and one that had not. They found that while there was some recovery of function in both groups, the lead-exposed rats did not recover as much or as quickly as did the unexposed animals.

Dr. Schneider presents his group’s findings Oct. 25, 2004, at the Society for Neuroscience’s annual meeting in San Diego.

In one test, they compared the animals’ abilities to walk across a narrow beam. Normally, rats can navigate the beam with few mistakes, he says.

“When we create the brain damage, initially, all of the animals make errors,” he says. “The control animals very quickly recover and make far fewer mistakes in the next week. The lead-poisoned animals take longer to improve, and improve much less.

“These results potentially add one more item to the long list of reasons why preventing lead exposure early in life is so important,” he says.

Next, the researchers want to examine the effects of lead poisoning on recovery from brain injury over a longer period of time. One question, says Dr. Schneider, is whether or not lead-poisoned animals eventually recover to the same degree as the unexposed animals. They also plan to try to determine if there is a threshold for lead exposure and its effects of the brain’s ability to recover following a brain injury.


Story Source:

The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.


Cite This Page:

Thomas Jefferson University. "Jefferson Neuroscientists Find Evidence Of Lead Exposure Affecting Recovery From Brain Injury." ScienceDaily. ScienceDaily, 28 October 2004. <www.sciencedaily.com/releases/2004/10/041027144351.htm>.
Thomas Jefferson University. (2004, October 28). Jefferson Neuroscientists Find Evidence Of Lead Exposure Affecting Recovery From Brain Injury. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2004/10/041027144351.htm
Thomas Jefferson University. "Jefferson Neuroscientists Find Evidence Of Lead Exposure Affecting Recovery From Brain Injury." ScienceDaily. www.sciencedaily.com/releases/2004/10/041027144351.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins